• 한방안이비인후피부과학회지
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• 제19권2호
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• pp.59-70
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• 2006

Objective : This study was performed to investigate the Anti-Inflammatory Effects of WooBangHaeGiTang on the Allergic Contact dermatitis. Method : Contact hypersensitivity assay, video microscope, WBC count, RBU count, neutrophil ratio, lymphpcyte ratio and GOT & GPT were measurd. Result : 1. At Contact hypersensitivity Aasay, at 24 hours after Control group & Sample group showed appreciably more ear swelling than Normal group, at 48 hours after Control group showed more ear swelling than Normal group & Sample group, at 72 hours after Control group & Sample group showed more ear swelling than Normal group 2. Regarding the number of WBC, at 24 or 48 hours after There are no significant difference among Normal group, Control group. Sample group, at 72 hours after Sample group showed more WBC than Control group. 3. Regarding the number of RBC, at 24 hours after Control group showed more RBC than Normal group, at 48 hours after Control group & Sample group showed more RBC than Normal group. at 72 hours after Control group showed more RBC than Normal group. 4. Regarding the percentage of neutrophil in WBC, at 24 & 48 hours after Control group & Sample group showed higher percentage than Normal group. 5. Regarding the percentage of Lymphocyte in WBC, at 24 hours after Sample group showed lower percentage than Normal group, at 48 hours after Sample group & Control group showed lower percentage than Normal group. 6. Regarding the GOT & GPT in blood, the GOT & GPT are in Normal scale, so there are no Hepatotoxicity in Normal group, Control group, Sample group. Conclusions : According to above experiments, WooBangHaeGiTang have some anti allergy effects on allergic contact dermatitis.

• 대한기계학회논문집A
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• 제20권1호
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• pp.115-126
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• 1996

In the time optimal control problem, bang-bang control has been used becaese it is the theoretical time minimum solution. However, to improve tracking speed performance in the time optimal control, it is important to select a switching point accurately which makes the velocity zero near the target track. But it is not easy to select the swiching point accurately because of the damping coefficient variation and uncertainties of modeling an actual system. The Adaptive model following control(AMFC) is implemented to relieve the difficulty and inconvenience of this task. The AMFC and make the controlled plant follow as closely as possible to a desired reference model whose switching point can be calculated easily and accurately, assuring the error between the states of the reference model and those of the controlled plant appoaches zero. The hybrid control method composed of AMFC and PID is applied to a tracking actuator of the magneto optical disk drive(MODD) in random access devices to improve its slow tracking performance. According to the simulaion and experimental results, the average tracking time as small as 20ms is obtained for a 3.5 magneto-optical disk drive. The AMFC also can be applied for other random access devices to improve the average tracking performance.

• 대한한방내과학회지
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• 제31권2호
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• pp.331-345
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• 2010

Objectives : This study was designed to investigate the effects of Saenggantanggami-bang (SG) on nonalcoholic fatty liver disease. Methods : HepG2 cells were used in an in vitro model. HepG2 cells were divided into three groups. The Normal group was incubated with no fatty acid. The Control group was incubated with 1mM palmitic acid to introduce fat overloading. The PA-SG group was incubated with 1mM palmitic acid and various concentrations of Saenggantanggami-bang (SG). Cell viability and cytotoxicity were analyzed by MTT assay and LDH assay. Intracellular triglyceride (TG) levels, reactive oxygen species (ROS) levels, ATP amount, and GST activity were measured. Cell death pattern and protective effect of SG on cell death were studied by DNA fragmentation and caspase-3 intensity (western blot). Results : Compared with the Control group, cell viability of the PA-SG group significantly increased (P<0.01), cytotoxicity of the PA-SG group decreased (P<0.01), and intracellular TG levels and ROS levels of the PA-SG group decreased (P<0.05). In DNA fragmentation assay, necrotic pattern was observed and DNA fragment decreased in the PA-SG group. In western blot, apoptotic pattern was observed, caspase-3 intensity of the PA-SG group was reduced significantly, but there were no significant differences in intracellular ATP amount and GST activity between the control group and the PA-SG group. Conclusion : The results suggest that Saenggantanggami-bang can be a potential candidate for the clinical treatment of nonalcoholic fatty liver disease.

• 동의신경정신과학회지
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• 제17권3호
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• pp.21-43
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• 2006

This study was designed to assess Effects of jingansikpungtanggagam-bang on Central Nerve System. Method : jingansikpungtanggagam-bang, a Korean traditional prescription, was evaluated for its anticonvulsant effect, hypnotic activity, analgesic action, anxiolytic effect, memory enhancement, and MAO inhibitory activity and detennined the content of neurotransmitter in brain by HPLC method. Result : 1. The extract increased potently anticonvulsant effect at 1g/kg by 5.6-fold extention of onset time against control group. 2. The extract increased hvrmsis at 500mg/kg by over twofold length of sleeping time compared to control. 3. The extract showed a significant analgesic effect with 86.0% inhibition on writhing frequency at 500mg/kg by phenylquinone-induced writhing test. 4. The extract inhibited dose-dependently the activity of monoamine oxidase in vitro. 5. This prescription increased the brain levels of serotonin and 5-hydroxyindoleacetic acid by 3.3% and 1.4%, respectively. 6. the extract exhibited the anxiolytic effect with 21.3% decrease of the immobility duration against control group. 7. the extract enhanced memory recovery on scopolamine-induced impairment of passive avoidance performance at 1g/kg pretreatment with 20.2% increase of latency time. Conclusion : The result sugguest that jiugansikpungtanggagam-bang can be used effectively as a sedative prescription in Korean traditional medicine.

• 한국항공우주학회지
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• 제38권9호
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• pp.882-889
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• 2010

수동형 진동제어 방식과 같이 시스템이 안정되며, 수동형에 비해 높은 제진 효과가 기대되는 반능동 진동제어 방식은 시스템의 안정화가 요구되는 우주구조물의 제진방법에 유효한 진동제어 방식중 하나이다. On-Off 제어방식에 근거한 반능동 제어는 On-Off 스위칭 시에 전달력의 불연속성으로 인한 chattering을 발생시킬 수 있으며, 이는 탑재체 구조물의 고유진동수와의 커플링으로 인하여 지향성능을 저하시키는 원인으로 작용할 수 있다. 본 논문에서는 chattering 영향 최소화를 통한 지향성능향상을 목적으로 LQ(Linear Quadratic)이론에 기반한 가변 감쇠형 반능동 제어기법을 제안하였다. 시뮬레이션 결과는 본 논문에서 제안한 반능동 제어기법은 기존의 skyhook와 LQ를 기반으로 하는 Bang-Bang 반능동 제어기법과 비교하여 높은 진동절연 성능을 나타내고 있다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1987년도 정기총회 및 창립40주년기념 학술대회 학회본부
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• pp.45-48
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• 1987

In applications of step-motor, the requirements of small-size and strong-power gave birth to feed-back drive to the maximum efficiency and complete damping. In this paper, a new scheme that determines switching times from sensed values of position and speed is presented for simple bang-bang type drive circuit. The optimal values of each phase switching times are obtained using conjugate gradient method.

• 혜화의학회지
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• 제22권2호
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• pp.57-66
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• 2014

Objectives : Features of military medicine and war pattern at the time Methods : "Haeng Gun Bang Pyeon Pyeon Bang", military medicine literature, that allows pattern of ancient war to be inferred was considered. First, background of this literature formation was examined, and the contents included were arranged based on table of contents. Lastly, pattern of war at the time and role of military medicine were studied through the meaning of times and medicine in this book. Results : This book was written by Naseyo(羅世瑤, of an unidentifiable period), an intellectual of Qing Period(淸代) in the 2nd year of Emperor Xianfeng(咸豊 2, 1852). It was composed of total 3 volumes and a book, and 684 prescriptions were written under 6 large sections(大門). Conclusions : This book was written in the middle of spirit of the times of national prosperity and military power caused by defeat in the Opium War and popular publication in a series, an academic current of the times. Though there were many treatments about external wound in this book, thoughts of armed forces and combat by people of the time were reflected, including drying method(乾法) making portable foods, drinking control method(戒酒法) to resolve drinking(飮酒) problem in the armed forces, treatment method of infectious disease, information collection method from enemy troops by confession, and various treatments for diseases of military horse. It is expected that this book will be good material for studies in the field of military medicine and used as material for diverse combination studies such as history and military science.

• Korean Journal of Acupuncture
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• 제24권4호
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• pp.163-180
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• 2007

Objective : Oriental medicines have been applied to Membranous nephropathy(MN) for the purpose on increasing renal blood flow and modulating immune activity in according to Oriental medicine theories. Magsungsinyeom-bang (MSSYB) is one of the prescription which is known to show positive results in clinic with lack of laboratorial evidence. Thus, this study was aimed to evaluate the effects of MSSYB and partially investigate the mechanisms of it. Methods : The effect of MSSYB was evaluated by the morphology for the GBM thickening, protein excretion in urine and biochemical parameters in serum using cBSA-induced MN mice model. Mice were administered with MSSYB(250 or 500 mg/kg) or PBS for control group from experimental week 3 for 4 weeks. Results : 24 hrs proteinuria and the concentrations BUN was significantly decreased in the MS groups compared to the control group while the concentrations of serum albumin was higher in the MS groups than control group. MSSYB didn't affect the ratio of CD3e+/CD or 19CD4+/CD8 in the spleen and kidney, but inhibit the expression of IL-1${\beta}$, TNF-${\alpha}$, IL-6, and production of IgG and IgM. In histological analysis of kidney tissue, thickening of GBM was significantly decreased in the MS group compared to control group. Conclusions : MSSYB showed the positive results on the cBSA-induced membranous nephropathy in mice, thus, it could be a useful candidate for oriental drug for treating the membranous nephropathy in clinic.

• 생물환경조절학회지
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• 제18권1호
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• pp.60-66
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• 2009

나물로 이용되는 방아풀, 쑥부쟁이 및 씀바귀의 효율적인 건조방법을 구명하고자 건조방법을 달리하여 건조한 후 메탄올을 용매로 한 추출액 $1,000mg{\cdot}L^{-1}$ 생리활성을 조사하였다. 총 페놀 함량은 방아풀과 쑥부쟁이는 동결건조 한 것에서 각각 65.1 및 $60.2mg{\cdot}L^{-1}$로, 씀바귀는 오븐에서 건조한 것에서 $51.2mg{\cdot}L^{-1}$로 가장 많았다. 총 플라보노이드 함량은 방아풀은 오븐건조 처리구에서 $70.6mg{\cdot}L^{-1}$로, 쑥부쟁이와 씀바귀는 동결건조 처리구에서 각각 53.9 및 $35.8mg{\cdot}L^{-1}$로 가장 많았다. 전자 공여능은 방아물의 경우동결건조 한 것에서 78.8%로 가장 높았으며, 쑥부쟁이는 $89.8{\sim}90.9%$로 유의성을 나타내지 않았다. 씀바귀 추출물의 전자 공여능은 오븐으로 건조한 것(91.9%), 자연건조 한 것(91.0%), 동결건조 한 것(90.9%) 순으로 높았다. 아질산염 소거능은 방아풀과 쑥부쟁이는 자연건조 한 것에서 각각 73.3및 78.2%로 높았으며, 씀바귀는 동결건조 한 것에서 75.1%로 가장 높았다.

• 소음진동
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• 제7권1호
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• pp.161-168
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• 1997

The present paper describes the vibration control experiment of composite plates with bonded piezoelectric sensor and actuator. The system is modeled as two degree-of-freedom system using modal coordinates and the system parameters are obtained from vibration tests. Kalman filter is adopted for extracting modal coordinates from sensor signal, and control algorithms applied to the system are Linear Quadratic Gaussian(LQG) control, Bang-Bang Control (BBC), Negative Velocity Feedback(NVF), Proportional Derivative Control(PDC). From observation of the spillover and control perfomance, it is concluded that a higher order control algorithm such as LQG rather than BBG, NVF, PDC is suitable for efficient simultaneous control of both bending and twisting modes of composite plates.