• Journal of Korean Neurosurgical Society
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• 제53권2호
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• pp.77-82
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• 2013

Objective : Sudden major cerebral artery occlusion often resists recanalization with currently available techniques or can results in massive symptomatic intracranial hemorrhage (sICH) after thrombolytic therapy. The purpose of this study was to examine mechanical recanalization with a retrievable self-expanding stent and balloon in acute intracranial artery occlusions. Methods : Twenty-eight consecutive patients with acute intracranial artery occlusions were treated with a Solitaire retrievable stent. Balloon angioplasty was added if successful recanalization was not achieved after stent retrieval. The angiographic outcome was assessed by Thrombolysis in Cerebral Infarction (TICI) and the clinical outcomes were assessed by the National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS). Results : At baseline, mean age was 69.4 years and mean initial NIHSS score was 12.5. A recanalization to TICI 2 or 3 was achieved in 24 patients (85%) after stent retrieval. Successful recanalization was achieved after additional balloon angioplasty in 4 patients. At 90-day follow-up, 24 patients (85%) had a NIHSS improvement of ${\geq}4$ and 17 patients (60%) had a good outcome (mRS ${\leq}2$). Although there was sICH, there was one death associated with the procedure. Conclusion : Mechanical thromboembolectomy with a retrievable stent followed by additional balloon angioplasty is a safe and effective first-line therapy for acute intracranial artery occlusions especially in case of unsuccessful recanalization after stent thrombectomy.

• Journal of Korean Neurosurgical Society
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• 제45권6호
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• pp.360-368
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• 2009

Objective : The objectives of this study were to analyze the recanalization rates and outcomes of multimodal therapy that consisted of sequential intravenous (IV)/intra-arterial (IA) thrombolysis, mechanical thrombolysis including mechanical clot disruption using microcatheters and microwires, balloon angioplasty, and stenting for acute ischemic stroke, and to evaluate the prognostic factors related to the outcome. Methods : Fifty patients who were admitted to the hospital within 8 hours from ischemic symptom onset were retrospectively analyzed. Initial IV thrombolysis and subsequent cerebral angiography were performed in all patients. If successful recanalization was not achieved by IV thrombolysis, additional IA thrombolysis with mechanical thrombolysis, including balloon angioplasty and stenting, were performed. The outcomes were assessed by the National Institute of Health Stroke Scale (NIHSS) change and modified Rankin scale (mRS) and prognostic factors were analyzed. Results : Successful recanalization was achieved in 42 (84%) of 50 patients, which consisted of 8 patients after IV thrombolysis, 19 patients after IA thrombolysis with mechanical clot disruption, and 15 patients after balloon angioplasty or stenting. Symptomatic hemorrhage occurred in 4 (8%) patients. Good outcomes were achieved in 76% and 70% of patients upon discharge, and 93% and 84% of patients after 3 months according to the NIHSS change and mRS. The initial clinical status, recanalization achievement, and presence of symptomatic hemorrhage were statistically related to the outcomes. Conclusion : Multimodal therapy may be an effective and safe treatment modality for acute ischemic stroke. Balloon angioplasty and stenting is effective for acute thrombolysis, and produce higher recanalization rates with better outcomes.

• 대한핵의학회지
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• 제33권2호
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• pp.163-171
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• 1999

목적 : 혈관 재협착을 막기 위하여 풍선에 용액 형태의 베타 방출 핵종을 넣어 사용하는 방법이 연구되고 있다. 이 연구에서는 Re-188-DTPA를 풍선에 넣어 사용하는 경우 주위 혈관에 대한 에너지 분포와 용액이 풍선에서 누출되는 경우 주요 장기와 전신에의 흡수 선량을 계산하였다. 대상 및 방법: 전자와 광자의 물에서의 운반은 몬테카를로 EGS4 코드를 사용하였으며 풍선은 직경 3 mm, 길이 20 mm의 원기둥으로 대체하였다. 개에게 Re-188-DTPA 370MBq를 주사하여 감마카메라로 영상을 얻어 주요장기의 잔류 시간을 구하였고 전신과 주요 장기에의 흡수 선량은 MIRDOSE3와 ICRP Dynamic Bladder모델을 사용하여 계산하였다. 결과: 3,700 MBq/1ml을 100초 동안 조사하였을 때 풍선 표면에 전달된 에너지는 17.6 Gy, 표면으로부터 0.5 mm 떨어진 곳에서 9.5 Gy이었다. 풍선에서 용액이 누출되었을 경우 전신에 0.005 mGy/MBq, 방광에 2.39 mGy/MBq의 흡수 선량이 전달되었다. 결론: 관상동맥 풍선 성형술용 풍선에 Re-188-DTPA를 주입하여 사용하는 방법이 목표선량을 조사하는 데 적절하고 방사선 안전의 관점에서 사용 가능한 방법이라고 생각한다.

• Journal of Chest Surgery
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• 제54권6호
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• pp.500-508
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• 2021

Background: The major limitation of arteriovenous graft access is the high incidence of thrombotic occlusion. This study investigated the outcomes of our salvage strategy for thrombosed hemodialysis arteriovenous grafts (including surgical thrombectomy with balloon angioplasty) and evaluated the efficacy of intragraft curettage. Methods: Salvage operations were performed for 290 thrombotic occluded arteriovenous grafts with clinical stenotic lesions from 2010 to 2018. Of these, 117 grafts received surgical thrombectomy and balloon angioplasty from 2010 to 2012 (group A), and 173 grafts received surgical thrombectomy and balloon angioplasty, with an additional salvage procedure using a curette and a graft thrombectomy catheter, from 2013 to 2018 (group B). Outcomes were described in terms of post-intervention primary patency and secondary patency rates. Results: The post-intervention primary patency rates in groups A and B were 44.2% and 66.1% at 6 months and 23.0% and 38.3% at 12 months, respectively (p=0.003). The post-intervention secondary patency rates were 87.6% and 92.6% at 6 months and 79.7% and 85.0% at 12 months, respectively (p=0.623). Multivariate Cox regression analysis demonstrated that intragraft curettage was a positive predictor of post-intervention primary patency (hazard ratio, 0.700; 95% confidence interval, 0.519-0.943; p=0.019). Conclusion: Surgical thrombectomy and balloon angioplasty showed acceptable outcomes concerning post-intervention primary and secondary patency rates. Additionally, intragraft curettage may offer better patency to salvage thrombotic occluded arteriovenous grafts with intragraft stenosis.

• 대한영상의학회지
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• 제84권5호
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• pp.1185-1190
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• 2023

가성동맥류는 경피적 풍선성형술의 가장 심각한 합병증 중의 하나이다. 가성동맥류의 파열은 드물게 발생하지만, 발생할 경우 환자의 죽음을 초래할 수 있기 때문이 조기 발견과 적절한 치료가 매우 중요하다. 저자들은 3개월 전 실시한 경피적 풍선성형술의 합병증으로 발생된 증상을 동반한 좌측 슬와동맥 거대 가성동맥류를 가진 34세 말기신부전 남자 환자의 증례를 보고한다. 가성동맥류는 인터벤션 치료를 통하여 성공적으로 치료되었고, 환자는 추적기간 동안 다른 합병증 없이 잘 회복되었다.

• Journal of Chest Surgery
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• 제48권2호
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• pp.120-125
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• 2015

Background: The purpose of this study was to evaluate the use of a Fogarty arterial embolectomy catheter (Fogarty catheter) in intraoperative balloon angioplasty of the cephalic vein, in order to determine its effect on the patency of arteriovenous fistulas (AVFs) created for hemodialysis access. Methods: A total of 156 patients who underwent creation of an AVF were divided into two groups, based whether a Fogarty catheter was used during AVF creation. Group A (89 patients) comprised the patients who underwent balloon angioplasty with a Fogarty catheter during the operation. Group B (67 patients) included the patients in whom a Fogarty catheter was not used during the operation. Patient records were reviewed retrospectively and documented. The patency rate was determined by the Kaplan-Meier method. Results: The records of 156 patients who underwent the creation of an AVF from January 2007 to October 2011 were included. The mean follow-up duration was $40.2{\pm}19.4$ months (range, 1 to 97 months). The patency rates in group A at 12, 36, and 72 months were $83.9%{\pm}3.9%$, $78.3%{\pm}4.6%$, and $76.3%{\pm}4.9%$, respectively, while the corresponding patency rates in group B were $92.5%{\pm}3.2%$, $82.8%{\pm}0.5%$, and $79.9%{\pm}5.7%$, respectively. The patency rates in group B were found to be slightly higher than those in group A, but the difference was not statistically significant (p=0.356). Conclusion: Intraoperative balloon angioplasty of the cephalic vein using the Fogarty catheter is a simple and easily reproducible procedure, and it can be helpful in increasing AVF patency in cases of insufficient runoff or a suboptimal cephalic vein.

• Journal of Trauma and Injury
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• 제27권4호
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• pp.196-200
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• 2014

Budd-Chiari syndrome is an uncommon condition characterized by hepatic outflow obstruction. Direct suture of the injured Inferior vena cava in a patient with blunt hepatic trauma also may cause an equivalent condition. However, early diagnosis is possible with common symptoms and radiologic evaluation. Moreover, a transluminal approach with balloon angioplasty could prevent long-term complications of Budd-Chiari syndrome without repeated abdominal surgery.

• Journal of Yeungnam Medical Science
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• 제22권1호
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• pp.90-95
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• 2005

관상동맥파열은 중재시술시 간헐적으로 발생하는 합병증이지만 급성 심장눌림증으로 진행하여 치명적일 수 있다. 일반적으로 중재시술시 사용하는 유도철선에 의한 천공은 자연방누되는 경우가 많으나 본 예와 같이 풍선이나 죽상판 제거술 등으로 인한 천공은 매우 급격히 진행하여 생명이 위험할 수 있다. 과거에는 젤라틴이나 자가혈전을 이용하여 파열된 부위를 막거나 수술적 교정을 하였으나 시술이 매우 복잡하고 시술지연에 따른 문제가 많이 발생한다. 이식판 그물망은 동맥류의 치료를 위해 개발되어 유용하게 이용되어 지고 있다. 본 예와 같이 관동맥 성형술 중에 관동맥이 천공되어 위급한 경우에도 이식판 그물망은 유용한 치료법으로 이용될 수 있다.

• Journal of Korean Neurosurgical Society
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• 제49권3호
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• pp.157-162
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• 2011

Objective : Vasospasm of cerebral vessels remains a major source of morbidity and mortality after an aneurysmal subarachnoid hemorrhage (SAH). The purpose of this study was to evaluate the safety and efficacy of transluminal balloon angioplasty (TBA) for SAH-induced vasospasm. Methods : Eleven patients with an angiographically confirmed significant vasospasm (>50% vessel narrowing and clinical deterioration) were studied. A total of 54 vessel segments with significant vasospasm were treated by TBA. Digital subtraction angiography was used to confirm the presence of vasospasm, and TBA was performed to dilate vasospastic arteries. Medical and angiographic reports were reviewed to determine technical efficacy and for procedural complications. Results : TBA using Hyper-Glide or Hyper-Form balloons (MicroTherapeutics, Irvine, CA) was successfully accomplished in 88.9% vasospastic segments (48 of 54), namely, in the distal internal carotid artery (100%, n=7), the middle cerebral artery (100%), including the M1 (n=10), M2 (n=10), and M3 segments (n=4), in the vertebral artery (100%, n=2), basilar artery (100%, n=1), and in the anterior cerebral artery (ACA), including the A1 (66%), A2 (66%), and A3 segments (100%). Vessel diameters significantly increased after TBA. There were no cases of vessel rupture or thromboembolic complications. GCS at one day after TBA showed an improvement in all patients except one. Conclusion : This study suggests that TBA using Hyper-Glide or Hyper-Form balloons is a safe and effective treatment for subarachnoid hemorrhage-induced cerebral vasospasm.

• 대한의생명과학회지
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• 제11권1호
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• pp.23-29
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• 2005

Molecular imaging with targeted contrast agents enables tissues to be distinguished by detecting specific cell-surface receptors. In the present study, a ligand-targeted acoustic nanoparticle system is used to identify angioplasty-induced expression of tissue factor by smooth muscle cell within carotid arteries. Pig carotid arteries were overstretched with balloon catheters, treated with tissue factor-targeted or a control nanoparticle system, and imaged with intravascular ultrasound before and after treatment. Tissue factor-targeted emulsion bound and increased the echogenicity and gray-scale levels of overstretched smooth muscle cell within the tunica media, versus no change in contralateral control arteries. Expression of stretch-induced tissue factor in carotid artery media was confirmed by immunohistochemistry. The potential for abnormal thrombogenicity of balloon-injured arteries, as reflected by smooth muscle expression of tissue factor, was imaged using a novel, targeted, nanoparticulate ultrasonic contrast agent.