• The Journal of Korean Obstetrics and Gynecology
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• v.34 no.2
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• pp.62-81
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• 2021

Objectives: The purpose of this study is to review clinical studies and evaluate effectiveness of intravaginal administration of oriental medicine on vaginal atrophy in menopausal women. Methods: 'postmenopause', 'menopause', 'vaginal atrophy', 'atrophic vaginitis', 'vaginal cream', 'vaginal gel', 'pessary', 'suppository' were searched on 3 online databases (Pubmed, Cochrane Library, OASIS). The risk of bias was assessed by using Cochrane risk of bias (RoB) 2.0 tool. Results: 9 randominized controlled trials (RCTs) were selected among 489 articles. The types of intervention were intravaginal administration of oriental medicine. 6 studies showed that treatment group was better than placebo control group or both treatment group and western medicine control group improved similarly. 2 studies were not significant effective in some results and 1 study was not statistically significant. Conclusions: Intravaginal administration of oriental medicine can be an effective option in treating menopausal women with vaginal atrophy. but considering the small number and low quality of studies, further well-designed studies are needed to confirm the effectiveness of this treatment.

• International Journal of Knowledge Content Development & Technology
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• v.12 no.2
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• pp.57-75
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• 2022

Currently, it is not easy for most domestic public libraries to collect and provide reliable health information services on their own. Health information is distributed or professional, making it inconvenient for users to use. Based on the implications derived from the case study, the Library Health Information Integration Service Model was proposed as a specialized information service. The model consists of a composition shared by librarians, health and medical experts, and users, focusing on library websites that provide integrated health information integration services, and has the following features. First, it provides health and medical information on a specialized subject. Second, it provides integrated health and medical information services provided in various ways. Third, librarians and health and medical experts work together to provide information services. Fourth, users can freely use health information integration services online and offline. The model presented in this study means that libraries can play a leading role in health information integration services to increase the utilization rate of public libraries and further contribute to librarians serving as experts in health information services.

• Transactions of the Korean hydrogen and new energy society
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• v.33 no.6
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• pp.684-691
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• 2022

Hydrogen fuel cell electric vehicles are typically refueled at a wide range of temperatures (-40℃ to 85℃) in the hydrogen refueling station in accordance with the worldwide accepted standard. Currently, there is no traceable method by which to verify and calibrate the hydrogen flowmeters to be used at hydrogen refueling stations except for a water calibration process as a conventional method. KRISS hydrogen field test standard based on the gravimetric principle was developed to verify the measurement accuracy of the mass flowmeter to be used at hydrogen refueling stations for the first time in Korea.

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.07a
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• pp.289-291
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• 2021

최근 삶의 질이 향상된 것과는 다르게 만성질환을 겪게 되는 사람의 수는 점점 증가하고 있으며 만성질환은 꾸준히 관리해야 하는 질병이지만 일반 사람들이 스스로 모든 것을 관리하면서 꾸준하게 동기를 부여하기에는 쉽지 않다. 본 논문은, 이에 관해 관심을 가지며 사람들이 항상 사용하는 핸드폰에서 쉽게 개선을 할 수 있는 식습관을 계획하고 실천할 수 있는 동기를 부여하며 최종적으로 사람들의 식습관을 개선함과 동시에 건강개선도 할 수 있는 애플리케이션을 제작했다.

• Biotechnology and Bioprocess Engineering:BBE
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• v.9 no.2
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• pp.143-146
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• 2004

A surface plasmon resonance (SPR) imaging system was constructed and used to detect the hexahistidine-ubiquitin-tagged human parathyroid hormone fragment (His$\sub$6/-Ub-hPTHF(1-34)) expressed in Escherichia coli. The hexahistidine-specific antibody was immobilized on a thin gold film coated with ProLinker$\^$TM/ B, a novel calixcrown derivative with a bifunctional coupling property that permits efficient immobilizaton of capture proteins on solid matrices. The soluble and insoluble fractions of an E. coli cell lysate were spotted onto the antibody-coated gold chip, which was then washed with buffer (pH 7.4) solution and dried. SPR imaging measurements were carried out to detect the expressed His$\sub$6/-Ub-hPTHF(1-34). There was no discernible protein image in the uninduced cell lysate, indicating that non-specific binding of contaminant proteins did not occur on the gold chip surface. It is expected that the approach used here to detect affinity-tagged recombinant proteins using an SPR imaging technique could be used as a powerful tool for the analyses of a number of proteins in a high-throughput mode.

• Journal of the Korean Society of Marine Environment & Safety
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• v.26 no.3
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• pp.242-253
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• 2020

This study examined the ef ects of freshwater discharge by artificial dikes from the Kanwol and Bunam lakes on the dynamics in the Chunsu Bay, Yellow Sea, Korea, during the summer season based on three-dimensional numerical modeling experiments. Model performances were evaluated in terms of skill scores for tidal elevation, velocity, temperature, and salinity and these scores mostly exceeded 90 %. The variability in residual currents before and after the freshwater discharge was examined. The large amount of lake water discharge through artificial dikes may result in a dramatically changed density field in the Chunsu Bay, leading to an estuarine circulation system. The density-driven current formed as a result of the freshwater inflow through the artificial dikes (Kanwol/Bunam) caused a partial change in the tidal circulation and a change in the scale and location of paired residual eddies. The stratification formed by strengthened static stability following the freshwater discharge led to a dramatic increase in the Richardson number and lasted for a few weeks. The strong stratification suppressed the vertical flux and inhibited surface aerated water mixing with bottom water. This phenomenon would have direct and indirect impacts on the marine environment such as hypoxia/anoxia formation at the bottom.

• Journal of the Korean Association of Geographic Information Studies
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• v.12 no.1
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• pp.26-35
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• 2009

This paper will propose the efficient method that should be designed to utilize the design pattern of GoF(Gang of Four) for implementation of LBS(Location Based Service) mobile system. The design method proposed by this paper can design and implement system interface using creational patterns, structural patterns and behavioral patterns of design pattern from the user and mobile system viewpoint. The design method using design pattern can show increasing reusability of module and software, abridging the development time, minimizing the maintenance and decreasing the efficiency of memory of system to software development. Therefore, we used a design pattern in order to change the middleware applying geographic information system from mobile environment. Finally, the mobile system applied to design pattern shall contribute to showing high stability and reliability, improving reusability and scalability of module and software and developing efficient LBS mobile system.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.6
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• pp.850-858
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• 2002

The present study investigates in detail the combined effects of the Coriolis force and centrifugal force on the development of turbulent flows in a square-sectioned U-bend rotating about an axis parallel to the center of bend curvature. When a viscous fluid flows through a curved region of U-bend, two types of secondary flow occur. One is caused by the Coriolis force due to the rotation of U-bend and the other by the centrifugal force due to the curvature of U-bend. For positive rotation, where the rotation is in the same direction as that of the main flow, both the Coriolis force and the centrifugal force act radially outwards. Therefore, the flow structure is qualitatively similar to that observed in a stationary curved duct. On the other hand, under negative rotation, where these two forces act in opposite direction, more complex flow fields can be observed depending on the relative magnitudes of the forces. Under the condition that the value of Rossby number and curvature ratio is large, the flow field in a rotating U-bend can be represented by two dimensionless parameters : $K_{TC}$ =Re $\sfrac{1}{4}$√λand a body force ratio F=λ/Ro. Here, $K_{TC}$ has the same dynamical meaning as $K_{TC}$ =Re√λ for laminar flow.

• Fire Science and Engineering
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• v.29 no.3
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• pp.6-12
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• 2015

Indoor hydrant facilities are used to fight initial fires before more intense fire extinguishing activities. Fire extinguishing facilities should ensure good fire extinguishing performance and the safety of users. Indoor hydrant facilities are mostly installed in buildings and facilities, and users must manipulate valves, hoses, and nozzles manually. When the discharge pressure is higher than 0.70 MPa, there is a high possibility that problems with manipulation and hose breakdown can occur. To prevent these problems, a method to attach orifice-type decompression valves to the angle valves of indoor hydrant discharge outlets has frequently been used for decompression methods. However, the decompression performance was reduced due to structural problems of the decompression valves over time. Accordingly, based on three-stage initial pressures, applicable pressure ranges were selected by measuring the decompression performance according to the diameter of the decompression orifices. Based on the data, stable decompression valve models are proposed. These models have the lowest decrease in decompression performance, regardless of time.

• Korean Journal of Medicinal Crop Science
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• v.26 no.1
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• pp.32-41
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• 2018

Background: To obtain useful safflower resources for breeding and research of functional materials, the present study was conducted to determine fatty acid compositions and antioxidant activities of 281 safflower accessions collected from East Asia including South Korea. Methods and Results: Lipid contents and fatty acids compositions were evaluated using soxhlet extraction and gas chromatography, respectively. A antioxidant activities were analyzed using a spectrophotometer. The evaluation range of safflower accessions showed very wide variation. In terms of lipid contents, the China accessions were higher than the collection from other regions, whereas antioxidant activities did not differ among regions. The result of the principal component analysis showed that the first and second principal component cumulatively explained 90.6% of the total variation. In clustering the safflower accessions, the tree showed four major clades. Group II (16 accessions) was high in lipid content, oleic acid and linoleic acid, whereas group III (50 accessions) exhibited higher antioxidant activities than other groups. Conclusions: It was recommended that the China collections be utilized as a useful resource for research on functional oil materials. These results provided valuable information for safflower breeders and researchers of functional food.