• Tuberculosis and Respiratory Diseases
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• 제42권4호
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• pp.600-604
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• 1995

저지들은 캐나다 방문당시 복부 팽만감을 주소로 그곳 병원을 림프관평활근 종증을 진단받고 귀국 후 본 병원에서 매달 Depo provera를 근주하고 매달 폐기능 검사등을 실시하여 추적관찰하고 있는 폐와 후복강에 발생한 림프관평활근종증의 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Advances in pediatric surgery
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• 제2권1호
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• pp.17-25
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• 1996

Acute pancreatitis(AP) in children is not common but can be associated with severe morbidity rates and its diagnosis is often delayed. Thus, reported mortality rates range from 0 to 78%. We have treated 26 patients with AP from 5 to 17 years of age over the past 17 years. We are intended to assess the relevance of the prognostic criteria used to assess severity of adult AP and to review the etiology, clilical presentation, diagnosis, and management of AP in children. The authors retrospectively reviewed 26 children with AP managed in Kyung Hee University Hospital from 1978 to 1995. Among 26 patients with AP, male were 12, and female were 14. And the mean age of patients was 11.8 years. In 9(34.6%), no definitive cause was identified. Common causes of AP were trauma(23.1%) and biliary tract disease(23.1%). Other etiologies were viral infection(15.4%) and post ERCP(3.8%). The presenting features were abdominal pain(92.3%), vomiting(61.5%), fever(19.2%), submandibular pain(11.5%), and abdominal mass(7.6%). Back pain was rare(3.8%). Abdominal ultrasonographic findings were abnormal in 10 of 16 patients(62.5%) and abdominal CT findings were abnormal for 9 of 9 patients(100%). Seventeen patients(65.3%) were managed conservatively, and nine patients(34.6%) required surgical treatment. There was no mortality. To evaluate the severity of disease, we used the Imrie prognostic criteria used to assess the severity in adult AP. The number of positive criteria was correlated to the duration of hospitalization(r2=0.91) but statistically insignificant(p>0.05). But, the number of positive criteria was correlated to the operative incidence(r2=0.93) and statistically significant(p<0.05). The common causes of AP in children were unknown origin(34.6%), trauma(23.1%), and biliary tract disease(23.1%). Ultrasonography and computed tomography were useful imaging tools of AP in children. The Imrie criteria used to evaluate the severity in adult AP were suspected to be valuable to assess the severity of AP in children.

• 대한한방부인과학회지
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• 제18권3호
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• pp.51-66
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• 2005

Purpose : Investigate the effects of Haeganjeon water extract (HGJ) on immobilization-stress or cold-stress in C57BL/6J mice. Methods : Male C57BL/6J 30 mice of weighting 18${\pm}$2g, were divided into sixs groups including the immobilization-stress group(5heads), after immobilization-stress HGJ oral administration(500mg/kg) groups(5heads), cold-stress group(5heads) and after cold-stress HGJ oral administration(500mg/kg) groups(5heads). then we observed changes in the serum histamine and corticosterone level and changes immune system. Results : HGJ decreased the serum level of histamine and corticosterone increased by immobilization-stress or cold-stress. HGJ inhibited the release of histamine from mast cells. In addition, HGJ enhanced the cell viability of thymocytes decreased by immobilization-stress or cold-stress and decreased DNA fragmentation of thymocytes increased by immobilization- stress or cold-stress. Also, HGJ increased the cell viability of splenocytes decreased by cold-stress and decreased DNA fragmentation of splenocytes increased by cold-stress. HGJ decreased the population of thymic CD4+ cells increased by immobolization-stress. HGJ increased the population of B220+ cells decreased by immobilization-stress and decreased the population of Thy1+ cells increased by immobilization-stress. Also, HGJ decreased the population of splenic CD4+ cells increased by immobolization-stress. HGJ enhanced the production of ${\gamma}-interferon$ decreased by immobilization-stress or cold-stress and increased the production of interleukin-4 decreased by immobilization-stress. Furthermore, HGJ enhanced the phagocytic activity decreased by immobilization-stress or cold-stress and enhanced the level of nitric oxide decreased by immobilization-stress or cold-stress. Conclusion : HGJ may be useful for the prevention and treatment of stress via suppression of serum histamine and corticosterone level and enhancement of immune response.

• 동의생리병리학회지
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• 제21권4호
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• pp.835-841
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• 2007

The followings are concluded from the treatment of headache in Hyungsang medicine, focussed on 11 kinds of headaches in Donguibogam. Headache is classified into overall headache and migraine according to the affected region. The causes are divided into exogenous affection and internal injury; The former brings on headache due to Wind-Cold and headache due to Damp-Heat. The latter, reversal headache, headache due to adverse rising of phlegm, headache due to regurgitation of Gi, headache due to excessive Heat, headache due to excessive Damp, true headache, and alcoholic headache. Headache due to internal injury generally tends to show deficiency syndrome with external affection. Headache due to exogenous affections is common to those who have big head or white skin and to Bangkwang type, and woman. The primary causes are Wind-Cold and Wind-Heat. When the body is observed in the perspective of eight phases, Damp-Heat is to be produced in the front, and Dry-Damp, in the back. Headache due to Damp-Heat is susceptible to Yangmyeong meridian type whose body develops more in the front and to woman. In the perspective of the upper and the lower, Yangdu(that is, head) is related to Eumdu(that is, glans of penis). Headache is also caused by the problems of Eumdu ,such as deficiency of Essence in man, pathologic change of uterus in women, and San syndrome in lower abdomen. In the case of man, headache is frequently severe and difficult to treat because head is a root for man. Disharmony of Gi and blood between the right and the left brings out migraine and headache due to regurgitation of Gi. Migraine is usually accompanied by symptoms of exogenous affection and often afflicts Gi-type, Shin-type, Soyang meridian type, deer type, and Dam-type. Headache due to regurgitation of Gi is brought by Gi deficiency or blood deficiency so that symptoms of exogenous affection do not show. It is mainly common with old people and those who have sunken eyes induced by deficiency of stomach Gi. In the perspective of the upper, the middle, and the lower, the pathologic change of head, chest and abdomen also bring about headache. The pathologic cause of head is Wind-Heat ,which triggers overall headache, migraine, headache due to Wind-Cold, headache due to excessive Heat, The pathogen of chest is phlegm-Fire and brings out headache due to Damp-Heat and headache due to adverse rising of phlegm. The pathologic factor in abdomen is Cold-Damp and produces headache due to adverse rising of phlegm and headache due to excessive Damp. In case of women, headache is generally caused by phlegm-Fire and retention of undigested food.

• 한국정보전자통신기술학회논문지
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• 제13권3호
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• pp.219-225
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• 2020

인구고령화에 따라 노인의 근골격계질환의 유병률이 계속해서 증가하고 있다. 또한 근골격계질환은 2015년 기준으로 산재보험 보상급여에서 업무상질병 중 상위 세 번째로 사회 및 경제적 손실을 초래한 질환으로서 근로자들에게도 많이 발생하는 질병이다. 본 연구에서는 허리의 근골격계질환의 예방과 치료에 보조할 수 있는 조끼를 제작하여 실험을 통해 그 효과의 유무를 확인하고자 한다. 허리부분의 질환은 코어근육과 밀접한 연관이 있다. 따라서 제작한 조끼는 코어근육을 지지해 주는 형태로 제작하였다. 효과 검증을 위해 조끼의 착용 전과 후에 허리 신전 운동인 멕켄지 운동을 10회 실시하면서 코어근육에 해당되는 배속빗근(내복사근, Internal oblique), 배곧은근(복직근, Rectus abdominis), 척추세움근(척추기립근, Erector spinae)의 근전도 데이터를 수집하고 수집한 데이터를 근전도 분석 프로그램인RM-3를 통해 분석하여 각 근육의 10회 측정 시 RMS값을 구하고 그 평균값을 비교하는 실험을 진행했다. 데이터비교 이후 유의성 검증을 위해 PASW ver18.0을 통해 측정결과의 기술통계치 산출과 평균차를 검증하고, 실험 결과치에 대응표본 T검정을 시행하여 통계 처리를 했다. 통계분석의 유의 수준은 α=.05로 설정하고 통계처리를 진행하였다.

• Applied Microscopy
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• 제39권3호
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• pp.253-260
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• 2009

상처치유는 growth factor와 cytokine들의 복합적인 작용에 의해 일어나는 과정이다. GM-CSF는 호중구와 대식세포를 분화시키고 각질세포를 증식시키는 다면발현성 사이토카인으로 여러 세포에서 재조합되어 사용되고 있다. (주)핸슨바이오텍에서 개발한 rice cell 유래의 재조합 rrhGM-CSF는 다른 세포에서 유래된 GM-CSF들보다 탄수화물 측쇄가 많은 것이 특징이다. rrhGM-CSF의 창상치유효과를 알아보기 위하여 햄스터에 만성 당뇨를 유도하여 상처치유가 어려운 동물모델을 만든 후, 등쪽에 인위적으로 피부 전 층을 제거하여 창상을 유발하였다. 실험군에는 rrhGM-CSF가 포함된 연고를 적용하고, 대조군에는 base cream만을 적용하여 재상피화되는 과정과 피부조직의 구조 및 PCNA 반응을 통한 세포증식 정도를 비교하였다. 육안 및 조직학적 관찰 결과, rrhGM-CSF를 적용한 그룹의 재상피화 속도가 더 빨랐으며, PCNA 면역조직화학적 조사에서도 증식하는 각질세포의 수가 대조군보다 상대적으로 많은 것으로 나타남으로써, rrhGM-CSF에 의한 피부상처 치유 효과를 관찰할 수 있었다. 이러한 결과들로 미루어 보아 벼세포 유래의 rrhGM-CSF는 국소적인 피부 창상 치유에 효과적인 것으로 보이며, rrhGM-CSF의 풍부한 당화 사슬은 이 단백질이 상처부위에 안정된 상태로 기능을 나타냄으로써 효과를 오랫동안 지속시킬 수 있었던 것으로 사료된다.

• Journal of Animal Science and Technology
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• 제50권3호
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• pp.363-372
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• 2008

본 연구는 거세한우 비육시 섬유질배합사료의 급여가 발육, 사료이용성 및 도체특성에 미치는 효과를 구명하고, 기존의 분리급여 방법과의 경제성을 비교검토코자 실시하였다. 생후 약 6개월령(평균체중 153kg 내외)의 거세 한우 60두를 공시하였으며, 사양시험은 생후 6개월령부터 28개월령까지 약 22개월간 실시하였다. 시험설계는 배합사료와 볏짚 분리급여구(Control), 습식 섬유질배합사료 급여구(TMRⅠ), 맥강 20%(TMRⅡ) 및 40%(TMRⅢ) 함유 건식 섬유질배합사료 급여구 등 4처리로 하여 각 처리당 15두씩 완전 임의배치하였다. 일당증체량은 맥강 20%를 첨가한 건식 섬유질배합사료구가 0.70kg으로 모든 처리구에서 가장 높았으나 처리간에 유의적인 차이는 없었다(p>0.05). 전기간 kg 증체당 사료요구량은 대조구가 11.63kg 이었고, 섬유질배합사료 급여구인 TMRⅠ, TMRⅡ 및 TMRⅢ구는 각각 9.29, 10.46 및 10.71kg 이었다. 도체율과 거래정육율은 모든 처리구가 각각 59% 및 63% 내외로 처리간 유의적인 차이가 없었으며(p> 0.05), 배최장근 단면적, 등지방 두께, 육색 및 지방색 역시 처리간 차이가 없었다(p>0.05). 근내지방도는 TMRⅠ구가 5.0으로 분리급여구의 3.4보다 유의적으로 높았고(p<0.05), 육질 1등급 이상 출현율은 TMRⅠ구와 TMRⅡ구에서 높게 나타났다. 경제성 분석 결과 분리급여구에 비해 TMRⅡ구가 사료비는 25% 정도 절감되었고, 소득은 19% 정도 향상되는 것으로 나타났다. 이상의 결과로 보아 거세한우 비육시 섬유질배합사료 급여가 비육우의 생산성 및 도체특성 개선과 생산비 절감에 효과가 있을 것으로 사료된다.

• 대한의료기공학회지
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• 제2권2호
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• pp.185-199
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• 1998

Going back to long chinese medical history, there were many different methods of treatment according to the origin of local chinese areas, such as Bian-Shi(?石) from east, herbal therapy from west, acupuncturing from south, moxibustion from north, and mainpulating therapy from middle china. In the midst of these therapies, acupuncture needling had developed very much both in theories, shapes, usages and also in theraputic boundray. Historical books dealing with acupuncture had introduced and used Jiu-Zhen as a tool for acupuncture needling in common. But there are some differences between each texts about in shape, use, and there are also another different point of view about the interrelationship between Bian-Shi and Ji-Zhen. So the author, in this research, tried to look for how Jiu-Zhen had took on its real kinds, adaptive usages, theraputic boundaries, many different skills of needing. By researching over ${\ulcorner}$ Ling-Shu, Jiu-Zhen(靈樞,九鍼)${\lrcorner}$, ${\ulcorner}$ Ling-Shu, Jiu-Zhen-Shi- Yi-Yuan(靈樞,九鍼十二原)${\lrcorner}$, ${\ulcorner}$ Ling-Shu, Guan-Zhen(靈樞,官鍼)${\lrcorner}$, and by compar- ing them with the contents of Jiu-Zhen in ${\ulcorner}$ Zhen-Jiu-Yi-Jing(鍼灸甲乙經)${\lrcorner}$ ${\ulcorner}$Zhen-Jiu-Da-Cheng (鍼灸大成)${\lrcorner}$, the author discovered small conclusions such as following. 1. Taking Jiu-Zhen in a narrow sense, it only repesents nine different needle used in different cases. But in large sense, this means nine different deedling methods using each different needles which is represented in the form of Wu-Ci ( 五剌 ), Shi-Yi-Ci ( 十二剌 ) in ${\ulcorner}$ Ling-Shu, Guan-Zhen ${\lrcorner}$ 2. Jin-Zhen has been first originated from stone age as a substitute for Bian-Shi and through bronze and iron age, it followed a process of it's own shape and applicating functions. As an example, the moxibustional therapies shown in ${\ulcorner}$ Zu-Bi-Shi-Yi-Mai- Jiu-Jing ( 足臂十一脈灸經 )${\lrcorner}$ ${\ulcorner}$ Yin-Yang-Shi-Yi-Mai-Jiu-Jing ( 陰陽十一脈灸經)${\lrcorner}$ in ahead of ${\ulcorner}$ Nei-Jing ( 內經 )${\lrcorner}$ era, was relationship in acupuncturing skills and shape. So Jiu-Zhen had been originated on the base of Bian-Shi in ancient times to develop into delicate shape, skill, and theraputic foundation of modern oriental medicine.

• 대한의료기공학회지
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• 제19권1호
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• pp.1-24
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• 2019

Objective : The purpose of this study is to understand a medical Gigong's view of the human body through the analysis of medical Gigong techniques, and to understand the concept and treatment principle of Whidam's Su-Gi therapy as the Angyo(按蹻) Method of Doin Angyo(導引 按蹻) Methods : Among Medical Gigong, Sojucheon practice, Moosim-Gigong Riding stance, Moosim-Gigong Doinbeop, Hwalinsimbang Doinbeop and Donguibogam Jang-Bu Doinbeop were selected to analyze the practice method. The medical Gigong's views of the human body are organized into overviews and pathological perspective. The main concepts and clinical techniques of Whidam's Su-Gi therapy were summarized. Discussion : Understanding the principles of medical Gigong is necessary in order to understand the Angyo method of Doin Angyo. The principle of medical Gigong is to circulate around Three-Danjeon(丹田) on the human belly and Three-Gwan(關) on the human back by practicing medical Gigong, and to strengthen the life force by activating the viscera function by communicating between the limbs and the body. If there are Jeokchwi(積聚) and deviation, Whidam's Su-Gi therapy eliminates the Jeokchwi and adjusts the deviation. Conclusions : 1. The Angyo method of Doin Angyo originates from the practice of training to establish Danjeon for the right body and the right flow of air. 2. The principles of medical Gigong obtained through the analysis of Sojucheon(小周天) practice, Moosim-Gigong Riding stance, Moosim-Gigong Doinbeop, Hwalinsimbang Doinbeop and Donguibogam Jang-Bu Doinbeop are the medical Gigong's view of the human body and pathological perspective. 3. Whidam's Su-Gi therapy, which focuses on the elimination of Jeokchwi and the adjustment of deviation based on the medical Gigong's view of the human body, is a manual therapy that inherits the principle of the Angyo Method of Doin Angyo.

• 한국가금학회지
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• 제20권3호
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• pp.151-159
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• 1993

본 연구는 항콕시듐 제제로 광범위하게 쓰이고 있는 nicarbazin이 닭의 고온 스트레스에 미치는 영향을 조사하고자 16수의 SCWL 수탉 성계를 사용하여 실시하였다. 옥수수-대두박 위주의 사료에 두 수준(0 및 125ppm)의 rucarbazin을 첨가하여, 두 처리의 환경온도(21 와 35~$36^{\circ}C$)하에서 4일간의 예비실험 기간을 거친 후, 2일 동안의 시료 및 자료 수집기간을 가졌다. 건물 섭취량과 건물 배설량은 고온 스트레스에 의하여 유의한 영향을 받지 않았으나, ricarbazin 첨가에 의하여 증가하였다. 그러나 건물 대사율은 nicarbazin첨가에 의하여 유의하게 감소하였다. 고온 스트레스는 또한 음수량과 증발에 의한 수분 손실을 증가시켰고, nicarbazin은 이러한 효과를 더욱 심화시켰다. 혈액 pH는 고온하에서 nicarbazin 첨가에 의해 증가되었으며, p$CO_2$는 고온하에서 nicarbazin에 의해 감소되었다. 고온 스트레스는 또한 체온을 상승시켰으며 nicarbazin 첨가는 이러한 효과를 심화시켰다. 이상의 결과를 종합하면, 닭이 고온 스트레스를 받으면 체온이 상승하게 된다. 따라서 닭은 체온 상승을 억제하기 위하여 호흡수를 증가시켜(panting) 수분 증발을 통한 체열 방출을 많게 한다. 그러나 nicarbazin 첨가는 고온하의 수탉 체온 상승 폭을 워낙 크게 하므로, panting에 의한 체열 방출량 증가만으로는 정상 체온을 유지하기가 어렵게 되는 것으로 풀이된다