• Korean Journal of Environmental Agriculture
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• v.30 no.1
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• pp.31-36
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• 2011

BACKGROUND: Disposal of slurry animal manure produced by an anaerobic slurry-type barn method is not easy since the animal slurry contain high moisture content which makes solid-liquid separation a difficult process. However, recently, the interest about anaerobic digestion process as an environment-friendly waste disposal method has gained a wide interest because it can treat highly organic matter contained by the piggery slurry, decrease the odor after treatment, and enable the effective recovery of the methane gas which is a valuable energy resource. The objectives of this study were to identify the solubilization characteristics and to improve the anaerobic digestion efficiency of piggery slurry through full-scale anaerobic digestion experiments. METHODS AND RESULTS: In a full-scale continuous anaerobic digestion operation, the adaptability of single anaerobic digestion and its digestion efficiency were also evaluated in the farm field. The actual pH range and alkalinity concentration of piggery slurry used during the operation were comparatively higher than the concentrations of pH and alkalinity in the digestion tank which were stable at 7.5~8.0, 4,008 mg/L (as$CaCO_3$), respectively. The removal efficiency of organic matter (TCOD) by anaerobic digestion was 75~90% and methane gas production amount was at 0.33 L/L/day, a little higher than that of ordinary animal manure. CONCLUSION(s): Our findings showed higher recovery of highly purified methane and greater efficiency of anaerobic tank digestion since its methane gas content was at 65~70%.

• Journal of the Korean Society of Food Science and Nutrition
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• v.39 no.1
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• pp.8-13
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• 2010

The angiotensin converting enzyme (ACE) inhibition effect of soybean protein isolate hydrolysate was studied using protease. Soybean protein isolate was hydrolysed by seven enzymes (Alcalase 2.4 L, Flavourzyme 500 MG, GC 106, Multifect Neutral, Neutrase 0.8 L, Papain 30,000 and Protamex), enzyme concentrations (0, 0.5, 1.0 and 1.5%), at various hydrolysis times (0, 1, 2, 3, 4, 5 and 6 hr) and suspension concentrations (1, 5, 7, 10 and 15%). Absorbance at 280 nm, brix and ACE inhibitory activity of soybean protein isolate hydrolysates were investigated. Absorbance at 280 nm and brix of Alcalase 2.4 L treatment were higher than other enzyme treatments. The optimum condition of hydrolysis was Alcalase 2.4 L, 1% enzyme concentration, 5% suspension concentration for 4 hr. $IC_{50}$ value of ACE inhibitory activity of soybean protein isolate hydrolysate was $79.94 {\mu}g/mL$. These results suggest that soybean isolate protein hydrolysate from Alcalase 2.4 L may be of benefit for developing antihypertensive therapeutics.

• Proceedings of the KAIS Fall Conference
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• 2010.11a
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• pp.115-116
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• 2010

광역상수도의 경우 수자원공사 및 지방상수도 사업자들에 의해 전문적으로 수질을 관리하고 음용수를 보급하고 있으나 소규모 수도시설의 경우 전문능력을 갖춘 관리자가 아닌 마을의 대표자가 맡아 관리함에 따라 안정성 및 유지관리의 어려움이 자주 제기되고 있다.[1] 또한 소규모 수도시설의 경우 취수원으로 지하수나 계곡수를 이용하여 여과나 염소소독을 거쳐 음용수로 이용함에 따라 중금속 및 무기이온 등 각종 오염물질이 효과적으로 제거되지 않아 이를 사용하는 주민들이 불편함을 겪고 있는 실정이다. 환경부의 법정 수질 검사에 따르면 부적합 판정을 받은 곳의 대부분은 마을상수도와 소규모 급수시설인 것으로 나타났으며 초과 항목으로는 무기이온 중 특히 불소와 질산성질소 인 것으로 나타났다.[2] 이러한 문제점을 해결하고자 기존의 고도 정수처리 시설인 막여과, 오존처리, 활성탄 흡착 공정 등을[3-5] 적용하고 있으나 소규모 수도시설에 적용하기에는 유지관리, 규모, 경제적 측면 등 여러 한계점을 지니고 있다. 따라서 본 연구에서는 이러한 문제점을 해결하기 위한 방안으로 전기응집기술을 이용하여 음용수 수질기준을 초과하는 무기이온 중 불소와 질산성 질소를 제거하고자 하였다. 전기응집기술은 제거효율이 높고, 운전이 용이하며 부가적인 화학약품의 첨가가 불필요하다.[6,7] 또한 기존의 고도정수처리 기술에 비해 전기응집 공정은 처리효율과 경제적인 측면 모두를 만족시키고 있어 소규모 수도시설의 불소와 질산성질소를 효과적으로 제거할 수 있는 방안으로 판단된다. 본 연구에 사용된 실험장치는 직류전원공급장치 (DC power supply), 반응조, 전극으로 구성되어 있다. 직류전원공급장치는 최대전압 30 Volt, 최대 전류 30 Amper 까지 조절 가능하였으며 반응조의 크기는 14.5cm(w) ${\times}$ 9cm(L) ${\times}$ 22cm(H) 이고 실용적 1.5L이다. 반응조의 상부에는 전극이 고정될 수 있도록 0.5cm 간격의 홈을 만들어 제작 하였다. 전극은 가용성 전극인 알루미늄 (Al), 스테인레스스틸(SUS304)를 이용하였다. 이를 통해 전류밀도, 전극간격 등의 변수를 두어 최적의 전기응집 운전 조건을 파악하였으며 이는 소규모 수도시설의 수질개선 향상에 도움이 될 수 있을 것으로 판단된다.

• Herbal Formula Science
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• v.25 no.4
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• pp.509-526
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• 2017

Background and objectives : Soeumin Bojungykgi-tang (seBYTE) has been used to supplement qi in Korean medicine. It has been demonstrated to possess various biological functions such as anti-cancer, anti-aging and anti-inflammatory effects. The present study evaluated the protective roles of seBYTE in hepatotoxic in vitro and in vivo model. Methods : To investigate cytoprotective effect of seBYTE, HepG2 cells were pretreated with seBYTE and then subsequently exposed to $10{\mu}m$ AA for 12 h, followed by $5{\mu}m$ iron. Cell viability was examined by MTT assay, and expression of apoptosis-related proteins was evaluated by immunoblot analysis. For responsible molecular mechanisms, ROS production, GSH contents, and mitochondrial membrane potential were measured. In addition, hepatoprotective effect of seBYTE in vivo was assessed in $CCl_4$-induced animal model. Results : seBYTE prevented AA + iron-induced cytotoxicity in concentration dependent manner. In addition, ROS production, GSH depletion, and mitochondrial dysfunction induced by AA + iron were significantly reduced by seBYTE pretreatment. Furthermore, seBYTE recovered expression of the pro-apoptotic proteins such as PARP and pro-caspase-3. In animal experiment, plasma ALT and AST levels were significantly elevated in $CCl_4$ treatment, but seBYTE significantly decreased the ALT and AST levels. Moreover, seBYTE alleviated the numbers of histological activity index, percentages of degenerative regions, degenerated hepatocytes, infiltrated inflammatory cells, nitrotyrosine- and 4-hydroxynonenal-positive cells in liver. Conclusions : These results showed that hepatoprotective effect of seBYTE against on $CCl_4$-induced hepatic damages is partly due to antioxidative and anti-apoptotic process.

• Journal of Chest Surgery
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• v.31 no.3
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• pp.279-285
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• 1998

Exessive sweating of the palms and soles, is a psychologically and occupationally distressing and sometimes disabling condition. Hyperhidrosis is one of the common abnormalities in autonomic nervous system. There were no specific treatment on hyperhidrosis, so invasive thoracic sympathectomy via axillary thoracotomy or cervical approach had been used. Video-assisted thoracic surgery(VATS) is now mostly performed for treating of the palmar and axillary hyperhidrosis. From March 1996 to March 1997, 15 patients with bilateral palmar hyperhidrosis had been treated by the bilateral thoracic sympathectomy(T2, T3, T4) with thoracoscopic resection. The patient were evaluated preoperative and postoperative Digital Infrared Thermographic Imaging (DITI) at Kyung-Hee University Hospital. There were no case of the thoracotomy conversion. There were 3 complications ; pulmonary edema in 1 case, Horner's syndrome in 1 case, and gustatory hyperhidrosis in 1 case. More than half of the patients also had compensatory sweating in the lower abdomen, the buttocks, the back and the thighs. In conclusion, most of the patients were satisfied with the postoperative results of the thoracoscopic sympathectomy, including no more palmar and axillary sweating, less pain, better cosmetic appearances, decreased sweating of the face and soles. In addition, intraoperative temperature monitoring of the hands could estimate the successful thoracoscopic sympathectomy and the preoperative and postoperative Digital infrared thermographic imaging(DITI) could especially be the technique for the objective manifestation of the successful results of the thoracoscopic sympathectomy.

• Journal of Korean Society of Environmental Engineers
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• v.33 no.8
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• pp.583-590
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• 2011

The effect of the physical parameters in the reactor (aeration depth, bubble size, and surface area) and the alkalinity of the solution on the ammonia stripping by bubbling were evaluated. When an airflow of 30 L/min was bubbled below the solution surface in the range 6-53 cm, the ammonia removal rate were observed to be the same regardless of the bubbling depths. At pH 10.0 and a temperature of $30^{\circ}C$, the average rate constant and the standard deviation were $0.178h^{-1}$ and 0.004. No appreciable changes in the ammonia removal rate were also observed with varying the bubble size and the air-contacting surface area. Alkalinity of the solution was found to affect the ammonia removal rate indirectly. This is expected because the pH of the solution would vary with dissolution of gaseous $CO_2$ by air bubbling. The real wastewaters from landfill site and domestic wastewater treatment plant were tested. In the case of domestic wastewater (pH = 7.1, alkalinity = 75 mg/L), the ammonia removal rate was poor even with the control of pH to 9.3. The raw landfill leachate (pH = 8.0, alkalinity = 6,525 mg/L), however, showed the appreciable removal rate with increasing pH during aeration. When the initial pH of the leachate was adjusted 9.4, the removal rate was significantly increased without changing the pH during aeration.

• Journal of Conservation Science
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• v.30 no.2
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• pp.111-122
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• 2014

In Bongseon-ri site, the central type and the local type of the Baekje tombs co-exist together. Many swords with ring pommel which to regional leaders in Seocheon the Beekje government granted are excavated from these tombs. These represent that the regional leaders were controlled by the Baekje government gradually. Four swords with ring pommel and one simple sword are investigated metallurgically and we seek what swords have a function of weapon or what sword produce for grave goods. The simple sword is made by solid carburizing technology and quenching of heat treatment so it's possibly used as a weapon. In contrast, four swords with ring pommel has little chance of weapon because the blade of swords consists of microstructure that have low hardness and the back of swords don't have microstructure can absorb the shock. The most identical characteristic of the simple sword and swords with ring pommel is that they are possible to classify clearly into practical/non-practical tools. Additionally, according to non-metallic inclusion analysis result of these swords, w$\ddot{u}$stite and glass phase are found together. Thus, it is able to say that reduction method in low temperature is applied during smelting process.

• Journal of Animal Science and Technology
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• v.49 no.1
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• pp.51-58
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• 2007

Twenty Hanwoo steers (average body weight=440.8±32.4kg) were used to investigate the effects of fish oil supplementation on growth performance, fatty acid composition of longissimus muscle and carcass characteristics. The experiment was done with two treatment groups; FO-0, without fish oil and FO-3, supplemented with 3% fish oil. Total gain and average daily gain (ADG) of steers were similar between two groups. Fish oil supplementation had no effects on contents of protein, ether extract and ash in longissimus muscle. Contents of isoleucine and glycine in longissimus muscle were decreased by fish oil supplementation (p<0.05), but content of cystein was increased by fish oil supplementation (p<0.05). Fish oil supplementation decreased contents of myristic acid and eicosenoic acid in longissimus muscle (p<0.05), but increased contents of oleic acid and arachidonic acid in longissimus muscle (p<0.05). Contents of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in longissimus muscle were increased by fish oil supplementation p<0.05). Carcass weight, back fat thickness, rib-eye area, yield index and yield grade were similar between two groups. Meat color was improved by fish oil supplementation (p<0.05), Ratio of quality grade ‘1 or over’ increased by fish oil supplementation. Therefore, the present study indicating that fish oil supplementation had positive effects on content of oleic acids in relation to flavor of beef, contents of EPA and DHA in relation to human health and ratio of quality grade ‘1 or over’.

• The Journal of Korean Society for Radiation Therapy
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• v.24 no.2
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• pp.175-181
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• 2012

Purpose: This study aimed to analyze the influence of aquaplastic mask which is used for the radiotherapy for patients with head and neck cancer on patient positioning by analyzing the results of 2D/2D matching with the use of Exactrac 6D couch system. Materials and Methods: 2D/2D matching-based Image guidance was performed with the use of Exactrac 6D couch system on a total of 14 patients with head and neck cancer who received radiotherapy at this hospital in a period from June 2010 to June 2011. The adjusted 6D values obtained after the image guidance were classified into values related with patients and values not related with patients as to the correlation between the results. Results: In the analysis of the relation of each adjusted value to patients, the coefficient of determination ($R^2$) of longitudinal and pitch direction was 0.76, of longitudinal and yaw direction was 0.48, and of pitch and yaw direction was 0.42 although the coefficient of determination for above factors was 0.03 or less when the dependency of patients was excluded. Conclusion: It was demonstrated that intrinsic factors of aquaplastic mask had influence on the immobilization of patients by aquaplastic mask although various factors related with patients had influence on the immobilization of patients. It is believed that if these factors are adjusted, the treatment of patients with head and neck cancer can be more accurate.

• Korean Journal of Head & Neck Oncology
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• v.17 no.2
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• pp.190-193
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• 2001

Background and Objectives: Reliable and versatile free flap has become a mainstay in reconstruction of the head and neck. But until now pectoralis major myocutaneous flap (PMMCF) as workhorse is useful and has some advantages such as good viability, one-stage reconstruction and carotid protection. The objective of this study was to review the role and indication of PMMCF in this era of potent free flaps for head and neck reconstruction. Patients and Methods: Sixty one PMMCF and one hundred forty six free flaps used for head and neck reconstruction between 1991 and 2001 were reviewed retrospectively. We compared the applied sites of flap, the flap failure rate and complications. Results: Contrary to the free flap, use of PMMCF has gradually decreased after the middle of 1990s. PMMCF were mainly used for mucosal defect(33cases, 54.1%) and cervical skin defect(22cases, 36.1%) and free flap were mainly used for mucosal defect(129cases, 88.4%). In point of use of PMMCF according to years, from 1991 to 1997, 30cases(70%) are used to reconstruct mucosal defect and 12cases(29%) are used to reconstruct skin defect. But from 1998 to 2001, only 2cases(10.5%) are used to reconstruct mucosal defect and 13cases(68.4%) are used to reconstruct neck skin defect. In case of free flap, from 1991 to 1997, 41cases (87%) are used to reconstruct mucosal defect and from 1998 to 2001 88cases(89%) are used as same purpose. Three major necrosis (more than 50%) deveolped in 61 PMMCF (4.9%) and three major necrosis developed in 146 free flaps(2.1%). Conclusion: PMMCF is no longer flap of choice for primary reconstruction but it is a still one of a good tool in some head and neck reconstruction such as covering single wide defect of face or neck skin, back-up procedure of free flap, postoperative status, treatment of pharyngocutaneous fistula and covering vital structure.