• 동아시아식생활학회지
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• 제7권1호
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• pp.1-11
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• 1997

The purpose of this study was to describe the protein nutritional status of female collegians between nonvegetarian diet groups(14) and vegetarian diet groups(19). Daily intake, protein were calculated from food direct measurement. Urea/creatinine, muscle mass, fatique conditions and hematological parameter were calculated. Blood samples were analyzed for total protein, albumin ammonia, urea, uric acid, creatinine, BUN contents. The results obtained are summarized as following : 1) On total dietary intake, especially Fe, vitamin C, niacin intake, vegetarian groups were higher than non vegetarian groups. 2) On composition of EAA(essential amino acids), vegetarians were highter than non vegetarian of leucine contents, but were lower lysine and threonine contents. 3) On urea / creatinine excretion, vegetarians were higher than non begetarians. Muscle mass were non signicant, fatique condition, vegetarians were normal state. 4) Non vegetarians were increased serum albumin total protein, uric acid, ammonia but vegetarians were decreased BUN, ammonia after experimental diet intake. 5) In process of time after meal, non vegetarians were increased serum albumin total protein, BUN, but vegetarians were decreased ammonia.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2009년도 하계학술발표대회 논문집
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• pp.1272-1276
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• 2009

The purpose of this study is to introduce wasted heat recovery heat exchanger for different kind of material in HVAC systems in field. For the purpose of estimating the large volume rotary heat exchanger and cross flow plate heat exchanger in heat recovery ventilator.

• 대한한방내과학회지
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• 제38권5호
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• pp.592-599
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• 2017

Objectives: The purpose of this study was to report the improvement of dyspepsia in a patient with liver cirrhosis and pancytopenia following traditional Korean medical treatment. Methods: A patient who suffered from dyspepsia with liver cirrhosis and pancytopenia was treated with herbal medicine, acupuncture, cupping, and moxibustion. The effect of treatment was measured with a visual analogue scale (VAS). Results: After treatment, the symptoms of dyspepsia improved and VAS score decreased. Conclusions: Traditional Korean medicine (TKM) could be effective for treatment of dyspepsia in patients with liver cirrhosis.

• Journal of Pharmaceutical Investigation
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• 제25권3호
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• pp.265-270
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• 1995

The pharmacokinetics of norfloxacin (100 mg/kg, oral) in renal failure rabbits was studied. Renal failure rabbits were induced by the i.v. injection of folate (50,100 and 150 mg/kg). These produced significant increases of serum creatinine concentration $(S_{cr})$ and blood urea nitrogen (BUN). Plasma concentration and AUC of norfloxacin significantly increased. Elimination rate constant $(K_{el})$ of norfloxacin significantly decreased, and half-life $(t_{1/2})$ of norfloxacin significantly increased. Correlation between serum creatinine concentration $(S_{cr})$ and half-life $(t_{1/2})$ of norfloxacin, and correlation between BUN and AUC of norfloxacin have linear relationship respectively. These results suggest that adjustment or the dosage regimen of norfloxacin is desirable, and serum creatinine concentration $(S_{cr})$ as well as BUN can be used an index for adjusting the dosage regimen of norfloxacin in renal failure.

• 한국동물위생학회지
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• 제45권4호
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• pp.337-342
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• 2022

Calf diarrhea is a major health concern in the livestock industry that requires accurate analysis for appropriate treatment. Dehydration and electrolyte imbalance are the most significant consequences of diarrhea in calves. Until now, the reference values of blood analysis of Hanwoo neonatal calves have not been well known. Recently, portable blood analyzers have made it possible to immediately analyze blood in the farm and provide suitable treatment for the patients. We analyzed electrolytes, blood urea nitrogen (BUN) and glucose in the blood of 179 Hanwoo neonatal calves, including 79 with diarrhea. These 179 calves were divided into 3 groups based on their age. Values of sodium (Na⁺ ) and glucose were significantly lower in diarrheic calves (1~30 days), while potassium (K⁺ ) and chloride (Cl^- ) values were higher in diarrheic calves (1~30 days). BUN values, which are closely related to dehydration due to diarrhea, increased in diarrheic calves of all ages. Therefore, these data can be used as reference values for blood analysis and treatment of healthy or diarrheic Hanwoo neonatal calves within 30 days of age.

• Reproductive and Developmental Biology
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• 제34권3호
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• pp.201-205
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• 2010

The objective of this study was investigate the superovulation treatment and to relate concentrations of blood urea nitrogen(BUN) in Hanwoo donors. Thirty six, at random stages of the estrous cycle, received a CIDR. Four days later, the animals were superovulated with a total of 28AU FSH (Antorin, 2AU=1 ml) administered twice daily in constant doses over 4 days. On the 3th administration of FSH, CIDR was withdrawn and 25 mg $PGF_2a$ was administered. Cows were artificially inseminated twice after estrous detection at 12 hr intervals. The cows received $100\;{\mu}g$ GnRH at the time of 1st insemination. Embryos were recovered 7 or 8 days after the 1st insemination. Cows with BUN <10, 11~18 and ${\geq}$19 mg/dl had return of estrus of 34.6, 30.5 and 30.4 days respectively. Return of estrus after superovulation treatment was not significantly lower for cows with blood urea nitrogen (BUN) above 10 mg/dl than for cows with BUN below 10 mg/dl. Cows with BUN <10, 11~18 and ${\geq}$19 mg/dl had number of transferable embryos of $3.2{\pm}1.2$, $5.4{\pm}1.9$ and $4.1{\pm}2.1$ respectively.

• 대한예방한의학회지
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• 제3권1호
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• pp.36-36
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• 1999

From January 1994 to April 1997, there was 15 survivals who was admitted to the department of internal medicine, Wonkwang Oriental Medicine' Hospital in Cheun-ju, after ingestion of paraquat, and treated with Oriental and western medicine therapy. For the patients, I investigated clinical symptoms, gastroduodenoscopy, intake by oral and parenteral route, and output by urine and stool, serum ALP, AST. ALT, Bilirubin, BUN, Creatinine level and urine analysis. On admission day, the LFT level was as follows. The serum mean ALP, AST, ALT, Total Bilirubin and Direct Bilirubin was 10.05${\pm}$2.75 KAU, 66.67${\pm}$9.88 IU／L, 43.80${\pm}$7.74 IU／L, 1.89${\pm}$1.22 ㎎／dl and 1.10${\pm}$1.14 ㎎／dl respectively. After that day, administered Gamdutang and checked the mean LFT level regullary. Until the 3rd day, the mean ALP, AST, ALT, Total Bilirubin and Direct Bilirubin level was 11.0l${\pm}$3.16 KAU, 56.47${\pm}$7.19 IU／L, 59.00${\pm}$7.57 IU／L, 2.54${\pm}$1.78 ㎎／dl, 1.64${\pm}$1.59 ㎎／dl respectively. From 4th day to 7th day, the mean ALP; AST, ALT, Total Bilirubin and Direct Bilirubin level was 12.51${\pm}$3.49 KAU, 77.85${\pm}$7.17 IU／L, 58.00${\pm}$9.09 IU／L, 2.54${\pm}$1.97 ㎎／dl, and 1.80${\pm}$1.81 ㎎／dl respectively. From 8th day to 10th day, the mean ALP, AST, ALT, Total Bilirubin and Direct Bilirubin level was 12.43${\pm}$3.14 KAU, 41.13${\pm}$6.49 IU／L, 50.40${\pm}$7.17 IU／L, 1.66${\pm}$1.90 ㎎／dl and 1.14${\pm}$1.50 ㎎／dl respectively. From 11th day to 14th day, the mean ALP, AST, ALT, Total Bilirubin and Direct Bilirubin level was 12.30${\pm}$3.25 KAU, 31.07${\pm}$3.85 IU／L, 43.33${\pm}$5.49 IU／L, 1.62${\pm}$1.95 ㎎／dl, 1.17${\pm}$1.71 ㎎／dl respectvely. On admission day, the mean RFT level as follows. Serum BUN and Creatinine level was 28.73${\pm}$5.19 ㎎／dl and 1.82${\pm}$1.27 ㎎／dl respectively. After that day, administered Gamdutang and checked the mean RFT level regullary. Until the 3rd day, the mean BUN and Creatinine level was 32.12${\pm}$5.65 ㎎／dl and 2.31${\pm}$0.45 ㎎／dl respectively. From 4th day to 7th day, the mean BUN and Creatinine level was 31.07${\pm}$5.47 ㎎／dl and 1.92${\pm}$0.79 ㎎／dl respectively. From 7th day to 10th day, the mean BUN and Creatinine level was 17.47${\pm}$3.57 ㎎／dl and 1.33${\pm}$0.59 ㎎／dl respectively. From 11th day to 14th day, the mean BUN and Creatinine level was 11,93${\pm}$3.16 ㎎／dl, 1.27${\pm}$0.38 ㎎／dl respectively.

• Childhood Kidney Diseases
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• 제12권1호
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• pp.99-104
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• 2008

현미경적 다발성 동맥염은 폐출혈과 급속 진행성 사구체심염을 특징으로 하는 전신성 혈관염의 일종으로 소아에서는 매우 드문 질환이다. 저자들은 폐출혈과 급성 신부전을 동반한 7세 여아에서 신장조직검사와 p-ANCA 검사로 현미경적 다발성 동백염으로 진단 후 5년 뒤 2차 신장조직검사와 경구 ACE inhibitor, angiotensin II receptor blocker와 저용량의 cyclophosphamide를 투여 받은 환아를 7년간 추적관찰하였다. 발병당시에는 BUN 117 mg/dL, Cr 2.3 mg/dL이었으나, 퇴원시 BUN 20.8 mg/dL, Cr 1.6 mg/dL이었고, 최근 검사에서는 BUN 51.7 mg/dL, Cr 3.2 mg/dL으로 만성 신병증 소견을 보이고 있으며, 외래 추적 관찰 지속 중에 있다. 이에 문헌 고찰과 함께 증례 보고하는 바이다.

• 한국임상수의학회지
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• 제29권5호
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• pp.372-376
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• 2012

급성신손상은 높은 이환율과 치사율을 나타내는 심각한 질환이며, 허혈-재관류에 의한 신손상은 급성신손상의 중요한 원인이 된다. 본 연구는 미니돼지에서 급성신손상을 진단하는데 임상적으로 유용한 바이오마커를 찾아내기 위해 실시되었다. 세 마리의 미니돼지에서 60분간 신동맥을 결찰하여 양측성 신허혈을 유도하였다. 각 미니돼지에서 결찰 전, 결찰 후 0, 1, 3, 5일에 혈액 및 뇨 검체를 채취하였다. 혈청 및 뇨 검체에서 BUN, creatinine, 나트륨 및 요산을 측정한 후 나트륨 및 요산의 분획배설율($FE_{Na}$, $FE_{UA}$)을 산출하였다. 또한 IL-6, IL-18, L-FABA 및 GST를 Western immunoblotting을 실시하여 측정하였다. 결과에서 세 마리 미니돼지 모두 혈청 BUN과 creatinine 농도는 결찰 후 1일째에 유의적으로 증가하였다. 그러나 $FE_{Na}$와 $FE_{UA}$는 현저한 개체차를 보였다. 수술 전과 후를 비교했을 때 허혈 이후의 뇨 검체에서는 IL-6, IL-18, L-FABP 및 GST의 농도가 유의적으로 증가하였다. 결론적으로, $FE_{Na}$와 $FE_{UA}$에 대해서는 추가적인 연구가 필요하다고 생각되며, 혈청 BUN, creatinine과 뇨 IL-6, IL-18, L-FABP 및 GST는 돼지의 허혈-재관류 모델에서 다른 바이오마커와 함께 급성신손상을 진단하는 민감한 바이오마커가 될 수 있을 것이라 생각된다.

• 한국수정란이식학회지
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• 제18권3호
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• pp.203-213
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• 2003

혈액성분과 경제형질들 간의 상관관계를 규명하는 일은 한우의 능력을 예측하고 예견되는 능력에 맞추어 사양관리와 판매처를 결정할 수 있고, 기존의 종축선발 체계와 결합시킴으로서 선발의 정확도를 향상시킬 수 있는 효과를 기대할 수 있으므로 나름대로 중요한 의미를 갖는다. 본 연구는 축산기술연구소에서 사육하고 있는 한우 866두의 혈액 중 호르몬과 대사물질을 분석하여 혈액성분과 경제형질과의 표현형 상관관계를 분석하고 혈액 내 유용한 생리적인 형질을 발굴하여 능력이 우수한 개체의 조기선발 가능성 구명과 선발 기술을 개발하여 한우개량에 또 다른 방법을 제시 하고자 실시하였다. 혈청성분들과 경제형질들 간의 표현형 상관계수를 거세우와 비거세우로 구분하여 추정한 결과 혈청성분들과 도체형질들 간의 주요 상관은 다음과 같다. 24개월 출하체중과 상관도가 높은 혈청은 거세우에서는 BUN이었고 비거세우에서는 albumin과 IGF-1이었으며, 비육말기 21∼24개월령의 일당증체량과 상관도가 높은 혈청은 거세우에서는 cal-cium이었고 비거세우에서는 albumin으로 증체와 관련 있는 혈청은 거세우에서는 calcium 비거세우에서는 albumin으로 나타났다. 육질과 관련 있는 등지방 두께 및 지방교잡도와 상관도가 가장 높은 혈청은 거세우와 비거세우 모두 BUN이었고, 육량등급의 근간이 되는 육량지수와 상관도가 높은 혈청은 거세우에서는 calcium이었으며 비거세우에서는 testosterone이었으나 육질과 상관이 높은 BUN은 거세우와 비거세우 모두가 육량지수와는 음의 상관을 나타내었다.