• Title/Summary/Keyword: BTX-A

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BTX Treatment of a Petrochemical Plant by Sliding Arc Plasma (Sliding Arc Plasma를 이용한 석유공장에서의 BTX 처리효율에 관한 연구)

  • Kwon, Woo-Taeg;Kwon, Lee-Seung;Lee, Woo-Sik
    • Fire Science and Engineering
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    • v.29 no.6
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    • pp.65-70
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    • 2015
  • This research examines the removal efficiency of benzene, toluene, xylene (BTX) and total volatile organic compounds (TVOCs) by flowing VOCs, which are generated at a petrochemical complex in the Ulsan area, in a sliding arc plasma (SAP) reactor. The SAP reactor process is composed of 5 steps and the analysis was conducted using a BTX detector and TVOC measuring instrument. The removal efficiency of BTX was better at high concentration than at low concentration and the emitted TVOC concentration increased in later steps of the reactor. In addition, the removal efficiency improved, as the flow velocity increased. The maximum permissible concentration of TVOCs in the first step was about 481 ppm and showed over 94.83% efficiency when it was operated in the 2nd step at concentrations beyond 481 ppm. Therefore, there are many factors for improving the removal efficiency of SAP reactors at low concentration and measures should be prepared according to the application method for the various types of industrial reactors.

Nocturnal Bruxism and Botulinum Toxin Effect on the Subjects with Masseteric Hypertrophy (야간 이갈이와 교근비대 환자의 보툴리눔 독소 주사 효과)

  • Sohn, Seung-Mahn;Chung, Gi-Chung;Kim, Mee-Eun;Kim, Ki-Suk
    • Journal of Oral Medicine and Pain
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    • v.32 no.3
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    • pp.337-346
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    • 2007
  • This study aimed to evaluate a relation of bruxism with clinical effects of botulinum toxin type A(BTX-A) injection. 5 bruxers and 5 nonbruxers with bilateral masseter hypertrophy were participated in this study. After injecting 25 unit of BTX-A(Allergen Inc, $Botox^{(R)}$) into each masseter muscle, the thickness of masseter(Mm) and anterior temporalis(Ta) muscles was measured by ultrasonography and the maximum bite force was evaluated during a 9-month period. Self-estimation on the recovery of occlusal force during mastication was done as well. Regardless of presence of bruxsim, all subjects showed significantly reduced Ms thickness(p<0.001) and maximum bite force at $1^{st}$ molars(p=0.027) with their peak at 3 months after injection, which then started to return. No significant difference was observed in Ta thickness and the bite force at the central incisors. While self-estimated occlusal force was the least at 2 weeks after injection and then rapidly returned to the baseline level with full recovery at the time of 6 to 9 months after injection, the maximum bite force measured by bite force recorder did not recover the original value, particularly in the nonbruxer group. It is assumed that nocturnal bruxism can influence recovery of atrophic masseter and decreased occlusal force due to BTX-A injection. These findings suggest a need of occlusal appliance to control bruxism or clenching habit for longer clinical effect of BTX-A injection.

Correction of post-traumatic anterior open bite by injection of botulinum toxin type A into the anterior belly of the digastric muscle: case report

  • Seok, Hyun;Park, Yong-Tae;Kim, Seong-Gon;Park, Young-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.39 no.4
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    • pp.188-192
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    • 2013
  • Post-traumatic anterior open bite can occur as a result of broken balance among the masticatory muscles. The superior hyoid muscle group retracts the mandible downward and contributes to the anterior open bite. Denervation of the digastric muscle by injection of botulinum toxin type A (BTX-A) can reduce the power of the digastric muscle and help to resolve the post-traumatic anterior open bite. A patient with a bilateral angle fracture had an anterior open bite even after undergoing three operations under general anesthesia and rubber traction. Although the open bite showed some improvement by the repeated operation, the occlusion was still unstable six weeks after the initial treatment. To eliminate the residual anterior open bite, BTX-A was injected into the anterior belly of the digastric muscle. Following injection of BTX-A, the anterior open bite showed immediate improvement. Complication and relapse were not observed during follow-up. Long-standing post-traumatic open bite could be successfully corrected by injection of BTX-A into the anterior belly of the digastric muscle without complication.

The role of botulinum toxin type A related axon transport in neuropathic pain induced by chronic constriction injury

  • Bu, Huilian;Jiao, Pengfei;Fan, Xiaochong;Gao, Yan;Zhang, Lirong;Guo, Haiming
    • The Korean Journal of Pain
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    • v.35 no.4
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    • pp.391-402
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    • 2022
  • Background: The mechanism of peripheral axon transport in neuropathic pain is still unclear. Chemokine ligand 13 (CXCL13) and its receptor (C-X-C chemokine receptor type 5, CXCR5) as well as GABA transporter 1 (GAT-1) play an important role in the development of pain. The aim of this study was to explore the axonal transport of CXCL13/CXCR5 and GAT-1 with the aid of the analgesic effect of botulinum toxin type A (BTX-A) in rats. Methods: Chronic constriction injury (CCI) rat models were established. BTX-A was administered to rats through subcutaneous injection in the hind paw. The pain behaviors in CCI rats were measured by paw withdrawal threshold and paw withdrawal latencies. The levels of CXCL13/CXCR5 and GAT-1 were measured by western blots. Results: The subcutaneous injection of BTX-A relieved the mechanical allodynia and heat hyperalgesia induced by CCI surgery and reversed the overexpression of CXCL13/CXCR5 and GAT-1 in the spinal cord, dorsal root ganglia (DRG), sciatic nerve, and plantar skin in CCI rats. After 10 mmol/L colchicine blocked the axon transport of sciatic nerve, the inhibitory effect of BTX-A disappeared, and the levels of CXCL13/CXCR5 and GAT-1 in the spinal cord and DRG were reduced in CCI rats. Conclusions: BTX-A regulated the levels of CXCL13/CXCR5 and GAT-1 in the spine and DRG through axonal transport. Chemokines (such as CXCL13) may be transported from the injury site to the spine or DRG through axonal transport. Axon molecular transport may be a target to enhance pain management in neuropathic pain.

Screening for variations in anterior digastric musculature prior to correction of post-traumatic anterior open bite by injection of botulinum toxin type A: a technical note

  • Zdilla, Matthew J.
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.41 no.3
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    • pp.165-167
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    • 2015
  • It has recently been reported that long-standing post-traumatic open bite can be successfully corrected with botulinum toxin type A (BTX-A) injection into the anterior belly of the digastric muscle (ABDM). The report documented an individual with bilaterally symmetrical and otherwise unremarkable anterior digastric musculature. However, the existence of variant anterior digastric musculature is common and may complicate the management of anterior open bite with BTX-A injection. Screening for variant ABDM can be accomplished via ultrasound, computed tomography, and magnetic resonance imaging. Screening for variant ABDM should be performed prior to BTX-A injection in order to account for musculature that may exert undesired forces, such as inferolateral deviation, on the anterior mandible in patients with anterior open bite.

Application of botulinum toxin in maxillofacial field: Part II. Wrinkle, intraoral ulcer, and cranio-maxillofacial pain

  • Kwon, Kyung-Hwan;Shin, Kyung Su;Yeon, Sung Hee;Kwon, Dae Gun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.41
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    • pp.42.1-42.15
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    • 2019
  • Botulinum toxin (BTX) is used in various ways such as temporarily resolving muscular problems in musculoskeletal temporomandibular disorders, inducing a decrease in bruxism through a change in muscular patterns in a patient's bruxism, and solving problems in patients with tension headache. And also, BTX is widely used in cosmetic applications for the treatment of facial wrinkles after local injection, but conditions such as temporomandibular joint disorders, headache, and neuropathic facial pain could be treated with this drug. In this report, we will discuss the clinical use of BTX for facial wrinkle, intraoral ulcer, and cranio-maxillofacial pain with previous studies and share our case.

Suggestions for Energy Utilization Improvement of Fractionation and Hydrodealkylation Units Based on Exergy Analysis (엑서지 해석에 근거한 분별증류 및 수소첨가알킬제거 공정의 에너지 이용 개선 방안)

  • Chung, Yonsoo
    • Clean Technology
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    • v.12 no.2
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    • pp.95-100
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    • 2006
  • Fractionation and hydrodealkylation (HDA) units, subparts of BTX plant, were thermodynamically analyzed using the notion of exergy. Exergy values were calculated as the sum of physical and chemical exergies due to the existence of chemical reactions. The analysis was based on the simulation results with the aid of real operating data. Driving and material exergy losses were separately defined and quantified. Locations and the reason of major exergy losses were identified and improvement strategies were suggested. It was noted that the exergy analysis could provide a sound base for adopting the concept of industrial ecology and developing loss prevention schemes.

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The study to measure of the BTX concentration using ANN (인공신경망을 이용한 BTX 농도 측정에 관한 연구)

  • 정영창;김동진;홍철호;이장훈;권혁구
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.5 no.1
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    • pp.1-6
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    • 2004
  • Air qualify monitoring if a primary activity for industrial and social environment. Especially, the VOCs(Volatile Organic Compounds) are very harmful for human and environment. Throughout this research. we designed sensor array with various kinds of gas sensor, and the recognition algorithm with ANN(Artificial Neural Network : BP), respectively. We have designed system to recognize various kinds and quantities of VOCs, such as benzene, tolylene, and xylene.

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The Development of the VOCs Measurement System using Sensor Array (센서 어레이를 이용한 휘발성유기화합물 측정기기 개발)

  • Hong Chol-Ho;Kim Dong-Jin;Lee Jang-Hun;Kwon Hyuk-Ku
    • Environmental Analysis Health and Toxicology
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    • v.19 no.1
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    • pp.41-47
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    • 2004
  • Air quality monitoring is a primary activity for industrial and social environment. The government push for pollutants that must be monitored. Especially, the VOCs (Volatile Organic Compounds), which are very harmful for human and environment, should be controlled under the government policy. We have been developed a VOCs measurement system which recognize various kinds and quantities of VOCs, such as benzene, toluene, and xylene (BTX). Especially, we designed sensor array with various kinds of gas sensor and ANN (Artificial Neural Network) algorithm. The measured values for BTX have errors of-4ppm.

Formation of humus-bound residues in the course of BTX biodegradation in soil

  • Song, Hong-Gyu
    • Journal of Microbiology
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    • v.35 no.1
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    • pp.47-52
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    • 1997
  • To examine whether the xylene component of BTX (benzene, toluene, xylene) mixture is cometabolized and residues are produced in soil, $\^$14/C-labeled-0-xylene was added to sandy loam in combination with unlabeled benzene and toluene. After 4 weeks of incubation in a sealed system connected to an oxygen reservoir, 55.1% of the radiocarbon was converted to $\^$14/CO$\sub$2/, 3.0% was to 95.8% radiocarbon recovery. Biomass incorporation of o-xylene radiocarbon which was detected by fumigation/extraction was usually low (5.6%), but 32.1% radiocarbon became associated with soil humus. Most of the numus-bound radiocarbon was found in humin fraction. In addition to o-xylene, p-xylene and toluene also showed similar results. The evidence shows that some of their reactive methylcatechol biodegradation intermediates attach to the humic metrix in soil in preference to mineralization and biomass incorporation.

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