• 대한치과의사협회지
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• 제13권11호
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• pp.1021-1024
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• 1975

Bo-sung dental gold alloy was tested an physical properties, tarnish and corrosion restistance. The results were as follows : 1. No differences beween physical properties of Bo-Sung dental gold alloy and American Dental Association Specification No. 5. 2. Tarnish and Corrosion resistance of Bo-Sung dental gold alloy were favorable of dental uses. 3. Bo-Sung dental gold alloys showed equiaxed grain structure in microstructures.

• 한국의사학회지
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• 제13권2호
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• pp.93-107
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• 2000

To generalize how early-Chosun medical achievements represented by "Hyang Yak Jib Sung Bang" and "Eui Bang Yoo Chui" influenced the publishment of "Dong Eui Bo Gam", and what academic achievements of "Dong Eui Bo Gam" are, I have compared the compositions of "Dong Eui Bo Gam" to two representative medical literature of early-Chosun era and examined the changes in organizations, and I was able to find deep connections among "Dong Eui Bo Gam", "Hyang Yak Jib Sung Bang" and "Eui Bang Yoo Chui".

• 한국의사학회지
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• 제13권2호
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• pp.131-139
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• 2000

Through studies on "Dong Eui Bo Gam", I have found out that 'Yang Saing' theroy in "Dong Eui Bo Gam" is based on 'Cha Eum Ron' and "I Ching" has much influenced on "Dong Eui Bo Gam".

• 한국산학기술학회논문지
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• 제18권1호
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• pp.295-301
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• 2017

보툴리눔 신경독소는 콜린성 신경말단(부)을 선택적으로 공격하여 신경마비를 일으키는 신경독소로서, 그람양성을 띠고 내성포자를 형성하는 절대혐기성 세균인 보툴리눔 균(Clostridium botulinum)이 만들어낸다. 이 중 보툴리눔 A형 독소(BoNT/A)는 음식물과 물을 오염시킬 수 있으며 생물 무기나 생물 협박물질로 사용될 수도 있다. 이 때문에 독성을 탐지할 수 있는 예민한 분석방법과 중독을 치료할 수 있는 효능 있는 항독소를 개발해낼 필요성이 제기되어 왔다. 본 연구에서는 BoNT/A를 중화할 수 있는 단일클론 항체(mAb)를 생산하기 위하여 BoNT/A로 면역된 토끼의 항혈청에서 유래한 scFv 라이브러리를 인간 IgG와 융합시켰다. 그렇게 재조합된 scFvIgG 항체 단백질을 안정된 세포주에서 발현시켰고 항체 친화 크로마토그래피를 사용하여 scFvIgG mAb 단백질을 정제하였다. ELISA로 정제된 scFvIgG mAb 단백질의 효율성을 확인하였고, in vivo 실험으로 BoNT/A에 대한 중화능을 시험하였다. 독성 중화능 실험은 마우스를 사용하여 수행하였는데, 그 결과 scFvIgG 항체(10 ug)는 BoNT/A(100,000 $LD_{50}$)의 독성이 주입된 마우스를 완전히 방어하지는 못하지만 마우스의 생존 기간을 현격하게 연장시키는 것이 확인되었다. 이러한 결과들은 이 scFvIgG mAb가 BoNT/A를 중화하는 효능을 가지고 있다는 점을 제시한다.

• Journal of Electrical Engineering and Technology
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• 제9권6호
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• pp.2025-2035
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• 2014

The read range of UHF mobile readers can be extended by a booster for mobile RFID readers (BoMR). But in an environment where multiple BoMRs are installed, the read success rate may be decreased due to signal interference. This paper proposes three arbitration methods based on interference estimation with the purpose of enhancing the read success rate. A central arbitration server manages global information in centralized arbitration method (CAM) without broadcast/multicast communication facility. In fully distributed arbitration method (FDAM), all the arbitration messages are broadcasted from a BoMR to every BoMR, and each BoMR decides with broadcasted global information. Events in FDAM are serialized naturally with broadcasted messages. Cluster Distributed Arbitration Method (CDAM) forms clusters with multicasted BoMRs and a selected BoMR acts as an arbiter in the cluster. Such effects as lengthened read range, improved the read success rates of readers can be obtained by the proposed methods without any hardware modification. In order to evaluate the arbitration methods, the RFID system is modeled by using the DEVS formalism and simulated by using the DEVSim++.

• 한국의사학회지
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• 제19권2호
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• pp.119-143
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• 2006

Man-Byeong-Hoi-Chun(萬病回春) is a representative writing of Gong Zhongxian. It was generally used by Koreans in Joseon(朝鮮) era and issued many times in the latter period of Joseon dynasty. We investigated the Jeung-Bo-Man-Byeong-Hoi-Chun (增補萬病回春, An enlarged edition of the Man-Byeong-Hoi-Chun), which is published in the 17th century, coming to a conclusion like the followings. 1. In Joseon(朝鮮), there was the J eung-Bo-Man-Byeong-Hoi-Chun which was made through revision and enlargement of the Man-Byeong-Hoi-Chun written by Gong Zhongxian of China. 2. There are two versions of the Jeung-Bo-Man-Byeong-Hoi-Chun pressed in Joseon, which are written by Kim Yuk(金堉) in 1656 and by Kim Seok-ju(金錫胄) in 1679. 3. The representative medical books of Joseon such as Eui-Rim-Chual-Yo-Sok-J ip (醫林撮要續集), Dong-Eui-Bo-Gam (東醫寶鑑), J e-Jung-Sin-Pyeon(濟衆新編) contained quotations from the J eung-Bo-Man-Byeong-Hoi-Chun(增補萬病回春), not from the Man-Byeong-Hoi-Chun (萬病回春). 4. The Jeung-Bo-Man-Byeong-Hoi-Chun(增補萬病回春) contained not only the essence of the Chinese medicine but also new medical systems reflecting actual circumstances of Joseon at that time. So, it can be recognized as the foundation of the Joseon medicine in the latter period of the dynasty.

• 한국의사학회지
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• 제15권1호
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• pp.147-182
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• 2002

By studing the congestion theory of Choo Dan-kyei mentioned in "DongEuiBoGam", I have reached following conclusions. 1. Dan-kyei's congestion theory influenced greatly on "DongEuiBoGam". The congestion theory of "DongEuiBoGam" is built up with several theories centering round on Dan-kyei's theory and Huh-Jun's own opinion in addition. 2. Dan-kyei's congestion theory has given theoretical foundation to the classification and diagnosis of congestion reported in "DongEuiBoGam"-Congestion Chapter. 3. Dan-kyei's congestion theory offers many examples of symptoms reported in "DongEuiBoGam"-Congestion Chapter. It's shown well through outer symptoms, several congestion disease, congestion mass, and "congestion never sudden death", etc. 4. Dan-kyei's congestion theory has influenced greatly on treatment of congestion reported in "DongEuiBoGam"-Congestion Chapter, and it's well shown through spewing method, grand method in congestion treatment and common medicine of congestion, etc. 5. Dan-kyei's congestion theory offers variety of treating methods to symptoms caused by congestion reported in "DongEuiBoGam". It's shown variously through upper stomachache, stomachache, back pain, side pain, "San", joint pain, Summer disease, internal injury, cough and morning sickness, etc.. 6. Dan-kyei's congestion theory has factors that could be operated to common diseases of mordern people. They can be classified as food congestion, alcohol congestion, obstruction congestion and Qi congestion, and they are clinically very efficient.

• 대한가정학회지
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• 제34권2호
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• pp.129-142
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• 1996

This paper pursues a comparative study on the design and function of the ready-made Bo-Son and the Bo-Son Pattern based on teaching and learning materials. It intends to investigate whether the Bo-Son is designed to suit to Kinetics of foot or to give the ease of wearing and taking off. The following results came out through trial wearing. 1) The Bo-Son pattern suggested in teaching materials can not satisfy the wearers with partial modification due to design problem. On the other hand, the ready-made Bo-Son can satisfy them with partial modification. 2) The important factor in designing the pattern of Bo-Son is the posture of foot when putting on it, that is, the height of the heel of the foot from the floor, the length of the heel, the length of toe and the bending angle of toe. 3) As a result of this study, in the design of the improved Bo-Son pattern, it is most suitable when the size of foot is 230mm, the height of the heel of the foot is 12.5cm, and and angle of the front toe of a sock is 35$^{\circ}C$.

• 대한한의학회지
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• 제22권3호
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• pp.51-62
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• 2001

Objectives : In Oriental Medicine, the improvement of constipation is very important for patients at the acute stage of cerebrovascular accident. For constipation, oral medicine has usually been used but is not available to stroke patients with dysphagia and mental disorder, and may bring about side effects on the gastrointestinal tract. In such cases, general enema has been used for assistant therapy, We needed to develop a more effective enema technique on constipation of stroke patients. Methods : Sixty-three patients were researched. We treated 29 patients with Bo-Ryu enema and 34 patients with general enema. To compare the effect of the Bo-Ryu enema group with that of the general enema group, we analyzed general characteristics, bowel movement, abdominal examination and related symptoms. Results : Sixty-three patients comprised the Bo-Ryu (n=29) and general (n=34) enema groups. Between the Bo-Ryu and general enema groups, the Bo-Ryu enema was more effective than the general enema in the number of bowel movements, total and corrected amount of stool, tonus of rectus abdominis muscle and abdominal discomfort. However, there were not significant differences in the power of abdominal muscle, digestion and physical power. Among the subgroups, Bo-Ryu enema group was most effective in the number of bowel movements, total amount of stool and tonus of rectus abdominis muscle, and Bo-Ryu enema group was best in the corrected amount of stool and abdominal discomfort. Conclusions : Bo-Ryu enema should be considered as an effective and safe treatment for patients with constipation during the acute stage of cerebrovascular accident.

• The Korean Journal of Physiology and Pharmacology
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• 제19권4호
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• pp.349-355
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• 2015

We examined the effects of peripherally or centrally administered botulinum neurotoxin type A (BoNT-A) on orofacial inflammatory pain to evaluate the antinociceptive effect of BoNT-A and its underlying mechanisms. The experiments were carried out on male Sprague-Dawley rats. Subcutaneous (3 U/kg) or intracisternal (0.3 or 1 U/kg) administration of BoNT-A significantly inhibited the formalin-induced nociceptive response in the second phase. Both subcutaneous (1 or 3 U/kg) and intracisternal (0.3 or 1 U/kg) injection of BoNT-A increased the latency of head withdrawal response in the complete Freund's adjuvant (CFA)-treated rats. Intracisternal administration of N-methyl-D-aspartate (NMDA) evoked nociceptive behavior via the activation of trigeminal neurons, which was attenuated by the subcutaneous or intracisternal injection of BoNT-A. Intracisternal injection of NMDA up-regulated c-Fos expression in the trigeminal neurons of the medullary dorsal horn. Subcutaneous (3 U/kg) or intracisternal (1 U/kg) administration of BoNT-A significantly reduced the number of c-Fos immunoreactive neurons in the NMDA-treated rats. These results suggest that the central antinociceptive effects the peripherally or centrally administered BoNT-A are mediated by transcytosed BoNT-A or direct inhibition of trigeminal neurons. Our data suggest that central targets of BoNT-A might provide a new therapeutic tool for the treatment of orofacial chronic pain conditions.