The purpose of this study was to investigate the obesity and state of dietary intake of 216 young Korean females, and the influence of $\beta$-II, III Adrenergic receptor (AR) gene polymorphism upon obesity and dietary intake. The average weight, height and BMI of the subjects were 160 cm, 54 kg, and 20.9 kg/$m^2$, respectively. The average triceps skinfold thickness, waist circumference, hip circumference and WHR were 21.7mm, 73.1cm, 93.3cm and 0.78, respectively. The results of body composition measurement using bioimpedance method, average body fluid, body protein, mineral mass and body fat were 29.271, 7.22 kg, 6.79 kg and 19.16 kg, respectively. A dietary survey was conducted using 24-hour recall method. Average calorie intake was 1621 ㎉, which is 81% of Korean RDA. We detected 182 (84.3%) Gln27 (QQ) homozygotes and 34 (15.7%) Gln27Glu (QE) heterozygotes for $\beta$-II AR polymorphism. For $\beta$-III AR polymorphism, we detected 163 (75.5%) Trp64 (WW) and 53 (24.5%) Trp 64Arg (WR). The results of comparing of obesity by $\beta$-II AR gene polymorphism, obesity index and BMI of QE type were slightly higher than those of the QQ type. For $\beta$-III AR gene polymorphism, the mean BMI, obesity index, fat mass and percent body fat (%) of the WR type were significantly higher than those of the WW type (p < 0.05). These findings suggest that genetic variability in the human $\beta$-III AR is associated with obesity among young Korean females. We also evaluated the effect of the simultaneous presence of the $\beta$-II AR and $\beta$-III AR polymorphism on obesity. We found that the BMI and obesity index of the mutant type in both $\beta$-II AR and $\beta$-III AR were significantly higher than those of the type that has only one gene mutation or has no mutation (p < 0.05), indicating a synergistic effect of $\beta$-II AR and $\beta$-III AR polymorphism on obesity. No association was found between $\beta$-II Ad or $\beta$-III AR polymorphism and dietary intake.
Jang, Gook Chan;Kim, Eun Young;Rho, Young Il;Moon, Kyung Rye;Park, Sang Kee
Clinical and Experimental Pediatrics
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v.50
no.5
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pp.484-488
/
2007
Purpose : The purpose of this study was to determine the incidence and potential predictors of weight gain in older children and teens treated with valproate (VPA) for epilepsy. Methods : Sixty-five subjects aged 8 to 17 years of age, who began VPA treatment between January 1, 2001, and December 31, 2004, and who had documented weight and height measurements at medication initiation and at least one follow-up visit were retrospectively identified. Exclusion criteria were follow-up <6 months, discontinuation of VPA within 6 months, and concurrent therapy with medication known to affect weight (such as topiramate, carbamazepin). Body mass index (BMI) was calculated at initiation and either discontinuation of VPA or last follow-up and stratified into four categories: group 1, underweight <5%; group 2, appropriate 5-85%; group 3, potentially overweight 85-95%; group 4, overweight >95%. Results : Twenty-eight subjects (77.8%) remained within their same category and eight (22.2%) moved up at least one category. Weight gain (increase in BMI difference) was observed in 72.2% of the 36 subjects treated with VPA. Three factors, neurocognitive status (P=0.017), seizure type (P=0.001) and duration of VPA treatment (P=0.035) were identified to be significant predictors of BMI difference. Conclusion : VPA induces weight gain in children and teens with epilepsy. These factors which are normal neurocognitive status, primary generalized type and duration of VPA treatment over the 12 months were predictors for an increase of weight gain. Therefore potential weight gain should be discussed with patients before the initiation of therapy and BMI should be monitored closely.
Background: The role of obesity in prostate cancer etiology remains controversial. The aim of this study was to evaluate the relationship between obesity and prostate cancer risk. Materials and methods: Between January 2000 and June 2005, 286 patients suspected of having prostate cancer underwent prostate biopsy. The clinical records of the 286 study patients were retrospectively reviewed with regard to age, Body Mass Index (BMI), serum PSA, TRUS, and prostate biopsy results. They were stratified by BMI into three groups according to the cutoffs recommended for Asian populations: normal, BMI less than 23 $kg/m^2$; overweight, BMI 23 to 25 $kg/m^2$; and obese, BMI greater than 25 $kg/m^2$. Results: As for BMIs, 132 (46.2%) were normal, 95 (33.2%) overweight and 59 (20.6%) were obese. A total of 99 (34.6%) patients were diagnosed as having prostate cancer. In multivariate logistic regression analyses, no significant association was observed between BMI and prostate cancer detection. Conclusion: We initially hypothesized that obesity may be biologically associated with increased prostate cancer development. However, our study did not show a significant association between BMI and prostate cancer.
This study examined BMI distributions among older adults in three different countries: the U.S., Japan, and Korea. The paper also explored differences in the factors predicting BMI in the three countries using three data sets: the U.S. Longitudinal Study of Aging (LSOA II, 8,589 persons), the Nihon University Japanese Longitudinal Study of Aging (NUJLSOA, 2,888 persons), and the Korean Longitudinal Study of Ageing (KLoSA, 2,397 persons). Descriptive analysis and multiple regression were performed. Japanese older adults were somewhat lighter than Koreans with fewer people at the upper end of the BMI distribution. Distributions of BMI among both Koreans and Japanese are shifted leftward relative to Americans. There is less dispersion in the distribution of BMI for Koreans and Japanese than among Americans. The association between socioeconomic variables and BMI is stronger in the U.S. and Japan than in Korea. Demographic variables are strong predictors of BMI in Korea. In Japan, all health behaviors have significant effects on BMI. It is concluded that the relationships between behavioral, demographical, and socioeconomic factors and BMI are not the same across countries. Results have policy implications for the involvement of health practitioners in helping older adults to control weight.
The purpose of this research is to provide useable data for application in American and Korean apparel company. This data was developed by analyzing information of Korean and American body sizes obtained from "Size USA Project" and "Size Korea Project". The Subjects were 6,306 American females and 1,988 Korean females over 18 years old. 30 measurements and 14 computed values were chosen that were considered critical in making garments. And descriptive analysis, percentile analysis and t-test were used as statistical methods for analyzing measurements and computed value between the two countries. The results were as follows. It was determined that American women were larger and bigger than Korean women in all measurements and computed values, except for Shoulder Slope. Based on BMI values, we determined that American women had a distinct tendency towards being overweight. Through the comparison of drop values (i.e. the difference between Hip and Bust Girths or Hip and Waist Girths), ratio values (i.e. waist height divided by height) and Body Mass Index (BMI) between the two countries, we determined that American women's figures were shapelier than Korean women's. American women had higher hip heights and longer leg lengths for their height compared to Korean woman. Furthermore, the back shapes of Korean women were flatter than American women and BMI values indicated American women were relatively more overweight than Korean women.
This study was carried out to find the factors which are related to the weight gain during pregnancy of women and infant birth weight. The information of the general characteristics and pregnancy outcomes of the 506 women who had a delivery during Jan to Dec, 1997 in a hospital at Taegu area were collected from the medical records. The results are as follows. The mean age of the subjects was 29 years old and the average prepregnancy weight was 52.75kg. They gained 13.51kg of weight during the pregnancy. The weight gain during pregnancy was higher in prepregnancy BMI<20kg/m$^2$, the infant weight was heavier in groups that had over 14kg of weight gain during the pregnancy than other groups. The prepregnancy BMI was negatively correlated to weight gain during pregnancy(r=0.2825), and positively correlated to number of pregnancy(r=0.2146), number of living delivery(r=0.1409), and infant weight(r=0.1250). The baby weight was Positively correlated to weight gain during pregnancy(r=0.1392) and Apgar score(r=0.1627). The results showed that the prepregnancy BMI and weight gain during pregnancy may be the influential factors on the infant weight, thus we need to develop the specific nutritional management program according to the status of prepregnancy weight.
This study investigated a mechanism of naming a disease, as examining how obesity attain a status of disease. WHO(World Health Organization) warned 'The obesity is definitely a disease to need medical treatment' in 1996 and 1997. However, before then, obesity was classified as unusual or nonstandard body status but it was not categorized as a disease. In order to examine a mechanism how obesity attain the status of disease, this study examined the historical process of construction to obesity in discourse of disease and ontological reality of pathological epidemiological to obesity. As a result of this research, it was found that the medical community manipulated BMI(Body Mass Index) and deliberately narrowed the range of person's normal weight, and institutionalized sizism. Especially, it was found that as the medical community associated the body state of obesity with high blood pressure, diabetes, and etc that causes burden of medical expenses to patients, that was fatphobia. And it tried to from a medical control mechanism to assign obesity to an independent status of a disease. Based on this examination, this study found an entailment: the noninfectious disease such as obesity attains the status of disease not because of the pathologic reason but because of cultural or socio-economical reason which han nothing to do with any medical source.
The purpose of this study was to investigate the association of obesity with medical care use and costs according to overall diseases, cerebrovascular diseases (CVD), ischemic heart disease (IHD), hypertension (HTN) and diabetes mellitus (DM). The final sample was a group of persons who were free of diseases mentioned above and were not underweight. Their baseline screening program data and health insurance contribution data were connected with a 7-year medical claim database. The participants were classified according to their baseline BMI into normal, overweight, obese, and severely obese groups. Given the disease type, the total costs of DM showed the largest difference in each obesity group in both males and females. Also, the pharmacy costs for DM were more relevant than any other type of service to the obesity level. Considering the high prevalence of obesity and the relevantly increased medical care use and costs, there is a need for reduction in medical costs through obesity prevention efforts.
The purpose of this study was to investigate weight control and the relative influence of individual variables affecting children's attempts to control weight. The study subjects were 319 elementary school children. First, the average body height and weight of the children who participated in this study was somewhat larger in boys and similar in girls, as compared with the normal body shape of Korean children. More boys were classified as overweight than girls, based on BMI. Both boys and girls were dissatisfied with their body shape, and especially the girls showed higher dissatisfaction rate than the boys did. Almost half of the children were concerned about weight control and girls had higher concern than boys. Of the children, 38.8% had controlled their weight; however there was no difference between their sexes. There were significant differences between children who had and had not experienced weight control in the following variables: stress caused by obesity, body satisfaction, BMI, subjective body shape perception and concern about weight control. Therefore, discriminant function analysis was performed to determine the discrimination of these variables between the two groups. From the analysis results, the most critical factor was BMI in the boys and concern about weight control in the girls. This finding should be reflected in the design of weight control programs for children i.e., boys should be encouraged to perceive correctly their own body shape and to control weight by maintaining a well-balanced diet and moderate exercise over a long period of time, rather than by skipping meals, while girls should be inspired with sound values and attitudes regarding their body shape, rather than provided with the concrete information on how to control weight.
Park, Hyeok;Kim, Daeyeol;Kim, Dohyeong;Kuk, Doohong;Cho, Sungchae;Kim, Seokhwan;Kim, DongHyun
Journal of the Korea Academia-Industrial cooperation Society
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v.20
no.11
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pp.56-65
/
2019
This study examined effects of 12 weeks of body weight based combined exercise training (resistance training for 30 min, aerobic training for 30min) on body composition (% body fat, lean body mass, fat mass and BMI (body mass index)) and cardiovascular factors (ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV)) in elderly women. A total of 32 subjects participated in this study, and were randomly divided into either exercise group (n = 16, EG) or control group (n = 16, CG). All variables at pre-test were analyzed by independent t-test for baseline test, and all data post the study period were analyzed by two-way repeated measures ANOVA with contrast testing (α = 0.05). Our results indicate that body composition (% body fat, lean body mass, fat mass and BMI) in both EG and CG do not differ significantly. However, the right and left sides of baPWV in EG was significantly reduced, as compared to CG. Taken together, these results indicate that combined exercise training for 12 weeks positively influences the cardiovascular factors, and may prevent cardiovascular diseases in elderly females (over 65 years), thereby resulting in increased quality of life for the elderly.
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