• 제목/요약/키워드: BL13

검색결과 289건 처리시간 0.02초

Morphological Changes in Adipose and Liver Tissues by 17$\beta$-estradiol in Female Ovariectomized C57BL/6J Mice

  • Jeong, Sun-Hyo;Choi, Hyung-Kyu;Yoon, Mi-Chung
    • 대한의생명과학회지
    • /
    • 제13권2호
    • /
    • pp.99-104
    • /
    • 2007
  • To determine whether 17$\beta$-estradiol induces the morphological changes in adipose and liver tissues, we measured the effects of 17$\beta$-estradiol on adipose tissue mass, adipocyte histology and hepatic lipid accumulation in female ovariectomized (OVX) C57BL/6J mice. Compared to vehicle-treated control mice, 17$\beta$-estradiol-treated mice decreased adipose tissue mass and the size of adipocytes, and concomitantly increased the number of adipocytes in a dose-dependent manner. In addition, the administration of 17$\beta$-estradiol resulted in reduced hepatic lipid accumulation in a dose-dependent manner. These results suggest that estrogen may regulate adipocyte development and lipid metabolism in female OVX C57BL/6J mice.

  • PDF

Anti-inflammatory Activities of Cinanamomum burmanni Bl

  • Khatib, Alfi;Kim, Mi-Yeon;Chung, Shin-Kyo
    • Food Science and Biotechnology
    • /
    • 제14권2호
    • /
    • pp.223-227
    • /
    • 2005
  • Anti-inflammatory assay was conducted on 20 kinds of traditional Indonesian medicinal herbs using soybean lipoxygenase (SLO) and hyaluronidase (HAse). Cinnamomun burmanni Bl showed highest anti-inflammatory activity. Ethyl acetate fraction from methanol extract of C. burmanni Bl bark showing high SLO inhibitory activity was isolated using silica gel-60 column chromatography. Two compounds were isolated and purified through preparative HPLC. Through analyses of UV, $^1H-NMR$, $^{13}C-NMR$, EI-MS and $FAB^+-MS$, compounds 1 and 2 were identified as coumarin and 2-hydroxy cinnamaldehyde, respectively, among which 2-hydroxy cinnamaldehyde showed SLO inhibitory activity of $IC_{50}\;=\;60\;{\mu}M$. Both compounds did not exhibit HAse inhibitory activity.

Light Curve of BL Cam using KASINICS

  • 한장희;손정주;성현일;전영범
    • 천문학회보
    • /
    • 제36권2호
    • /
    • pp.149.1-149.1
    • /
    • 2011
  • 보현산 천문대의 근적외선 카메라시스템인 KASINICS(KASI Near Infrared Camera System)를 사용하여 다주기 변광성 BL Cam을 관측하였다. BL Cam(${\alpha}=03^h47^m19^s$, ${\delta}=+63^{\circ}22'7"$[J2000.0], V=13.10, ${\Delta}V$=0.33mag)은 광학적 쌍성으로 SX Pheoenics 변광성 중 하나이며 0.03 - 0.08day의 짧은 주기를 갖는 다주기 변광성으로 알려져 있다. 대상 천체의 적외선 관측을 위하여 한국천문연구원에서 개발한 지상 망원경용 근적외선 카메라 시스템 KASINICS를 사용해 J, H, Ks filter로 시계열 관측을 하였다. 대상 천체의 가시광 파장대에서의 관측 자료와 적외선 파장대에서의 관측 자료를 비교 분석함으로써 천체의 외곽층에서 발생하는 상호작용에 대해 알아볼 수 있다.

  • PDF

고 에너지 이온 주입된 CMOS 쌍 우물 구조의 레치업 면역성 예측을 위한 TCAD 모의실험 연구 (A Study on the TCAD Simulation to Predict the Latchup Immunity of High Energy Ion Implanted CMOS Twin Well Structures)

  • 송한정;김종민;곽계달
    • 한국전기전자재료학회논문지
    • /
    • 제13권2호
    • /
    • pp.106-113
    • /
    • 2000
  • This study describes how a properly calibrated simulation method could be used to investigate the latchup immunity characteristics among the various high energy ion implanted CMOS twin well (retro-grade/BILLI/BL) structures. To obtain the accurate quantitative simulation analysis of retrograde well, a global tuning procedure and a set of grid specifications for simulation accuracy and computational efficiency are carried out. The latchup characteristics of BILLI and BL structures are well predicted by applying a calibrated simulation method for retrograde well. By exploring the potential contour, current flow lines, and electron/hole current densities at the holding condition, we have observed that the holding voltage of BL structure is more sensitive to the well design rule (p+to well edge space /n +to well edge space) than to the retrograde well itself.

  • PDF

골절에 침 치료를 적용한 2013년 이후 증례보고 문헌고찰 (A Review of Case Reports on the Application of Acupuncture as a Treatment for Fracture since 2013)

  • 백승원;남경호;최승관;이정한;한윤희
    • 한방재활의학과학회지
    • /
    • 제31권4호
    • /
    • pp.49-63
    • /
    • 2021
  • Objectives This study aimed to investigate the trend in treating fracture with acupuncture and to evaluate the quality of case reports. Methods All case reports of fractures treated with acupuncture were extracted from four Korean web databases. We classified these studies by five fracture sites and investigated frequently used meridian and acupoint, outcome measurements, treatment period. And we assessed the quality of the case reports by the STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) guidelines. Results A total of 33 case reports were included. The outcome measurements were divided into six categories, and the outcome measurements used in more than three studies showed improvement in patient symptoms. The mainly used meridians for each fracture site were as follows: chest and abdomen (GB, LR, CV), back (BL, GB), upper limb (LI, TE), lower Limb (GB, ST, BL, SP). The most commonly used acupoints for each fracture site were as follows: chest and abdomen (Ashi points, GB24, GB25, GB26, LR13, LR14, CV16, CV17, CV18, CV19), back (BL23, BL24, BL25, BL26, BL40, BL51, BL52, BL60, GB34), upper limb (LI4, LI10, LI11, TE3), lower limb (GB34, GB40). According to the STRICTA guidelines, more than 54.54% of the reports were found to be 'not reported' or 'not sufficient' in the following categories: 'response sought', 'description of participating acupuncturist', and 'number of needle insertions per subject per session'. Conclusions The meridians and acupuncture points frequently used for acupuncture treatment of fractures were near the fracture site. Future clinical studies involving acupuncture must be reported in accordance with the STRICTA guidelines to improve transparency and uniformity.

체외생산된 소 배반포강 내의 아미노산 농도 (Amino Acid Concentrations in the Blastocoelic Fluid of In Vitro-Produced Bovine Blastocysts)

  • 정연길;;윤종택
    • 한국수정란이식학회지
    • /
    • 제13권3호
    • /
    • pp.251-259
    • /
    • 1998
  • 체외생산된 소 배반포 및 탈출 배반포강 내의 유리 아미노산 농도를 측정하였다. 체외 배양은 소 혈청알부민이 함유된 합성난관배양액(synthetic oviduct fluid; SOF)에서 실시하였으며 수정 후 180시간의 배반포 및 216시간 후의 탈출 배반포를 실험에 공여하였다 아미노산 측정은 알부민 대신 Polyvinyl alcohol이 함유된 SOF 미소적에 수정란을 분주하고 미세조작기를 이용하여 배반포강 내의 액을 추출하여 20종류의 아미노산을 측정하였다. 탈출 배반포는 isoleucine, leucine 및 methionine 농도가 배반포보다 유의적(p〈0.05)으로 높게 나타났으며, glutamate, aspartate는 두 군간에 차이를 나타내지 알았다. 반면 alanine 및 threamine (p〈0.01)과 cystine을 제외한 나머지 12종류의 아미노산(p〈0.001)은 배반포가 탈출 배반포에 비해서 유의적으로 높은 측정치를 나타내었다. 비록 glutamine의 경우 배양액 내에 첨가되지 않았으나 두 군, 특히 배반포 내에서 높은 측정치를 보였다. 본 연구결과로 보아 체외생산된 배반포 및 탈출 배반포는 내강에 필수 및 비필수 아미노산을 각기 다른 농도로 함유하고 있는 것으로 사료된다.

  • PDF

좌섬요통에 대한 BU 약침의 효과 (The Effects of BU Herbal Acupuncture on Low Back Pain of Sprain)

  • 서보명;이윤경;최성훈;김경운;윤종석;임성철;정태영;한상원;서정철
    • 대한약침학회지
    • /
    • 제8권2호
    • /
    • pp.5-10
    • /
    • 2005
  • Objectives : This study was designed to estimate the effects of BU herbal acupuncture theraphy on low back pain of sprain patients by using Visual Analogue Scale(VAS) and pressure algometer. Methods : 13 volunteers were applied to BU herbal acupuncture stimulation on the BL23, BL24, BL25 and BL26 acupoints. The degree of improvement of low back pain of sprain was evaluated by VAS and pain pressure threshold(at the points of BL23 and BL24 before treatment, before 3rd treatment(after herbal acupuncture). Results : In VAS scores, there were significant differences between before and after herbal acupuncture stimulation. But there was no significant difference between before and after herbal acupuncture stimulation in pain threshold. Conclusions : The effectiveness of BU herbal acupuncture theraphy on low back pain of sprain was shown through VAS and pressure algometer. These imply that BU herbal acupuncture theraphy may be useful for low back pain of sprain. Further study is needed about BU herbal acupuncture.

부항자극에 대한 체표 경락.경혈의 생체에너지 변화 분석 (Analysis of Meridians Energy change by Cupping Stimulation)

  • 김수병;이나라;김영대;임종현;송길수;정병조;이용흠
    • Korean Journal of Acupuncture
    • /
    • 제27권4호
    • /
    • pp.49-57
    • /
    • 2010
  • Objectives : The aim of this study is evaluation for significance of skin meridian-acupoints energy measurement system, and is verification of principle to measure the bio-ion charge on acupoints. Methods : To check a correlation between the MEP(Meridian Energy Potential) and bio-electric charge condition, ten acupoints(left/right BL meridian : BL13, BL15, BL18, BL20, BL23) were chosen. Based on basic theory concerning the upward trend of the bio-electric charge by cupping therapy, we measured MEP change before and after 600mmHg(80kPa) Negative pressure stimulation using cupping. Results : We could identify the correlation between MEP and the condition of bio-electric charge in acupoints. Also, we checked the balance or imbalance of left/right the MEP and unusual cases. Conclusions : We confirmed significance of proposed principle and meridian energy measurement system.

Ensiled Banana Wastes with Molasses or Whey for Lactating Buffaloes during Early Lactation

  • Khattab, H.M.;Kholif, A.M.;EI-Alamy, H.A.;Salem, F.A.;EI-Shewy, A.A.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제13권5호
    • /
    • pp.619-624
    • /
    • 2000
  • Low-quality roughages [banana wastes (B), wheat straw (WS) and dried broiler litter (BL)] were ensiled using either sweet whey (W) or diluted molasses (M) as rehydration media to study their effects on milk yield, milk composition and some parameters of blood plasma. The feeding trial involved 25 lactating buffaloes in five groups (five animals each). Buffaloes as control animals received diets of concentrate feed mixture, rice straw and wastelages (70:30:00). In the other 4 treatments, the wastelages replaced 50% of rice straw in the control diets. The wastelages were BL:B:M(3:2:10) (T1), BL:WS:M (3:2:10) (T2), BL:B:W (3:2:10) (T3) and BL:WS:W (3:2:10) (T4) on a fresh matter basis, during the 1st 17 weeks of lactation period. Results indicated that feeding lactating buffaloes on wastelages resulted in slightly higher (p>0.05) milk yield, 4% fat-corrected-milk yield and feed efficiency, and slightly lowered (p>0.05) contents of milk total solids, fat and protein. Wastelages, especially BL-B-M, increased (p<0.05) milk non-protein-nitrogen and ash contents and plasma urea, GOT and GPT. The results demonstrate that banana plant wastes with some additives in silage form may be good untraditional roughage for lactating buffaloes without any adverse effect on milk production.

Estimation of bioluminescence intensity of the dinoflagellates Noctiluca scintillans, Polykrikos kofoidii, and Alexandrium mediterraneum populations in Korean waters using cell abundance and water temperature

  • Sang Ah Park;Hae Jin Jeong;Jin Hee Ok;Hee Chang Kang;Ji Hyun You;Se Hee Eom;Yeong Du Yoo;Moo Joon Lee
    • ALGAE
    • /
    • 제39권1호
    • /
    • pp.1-16
    • /
    • 2024
  • Many dinoflagellates produce bioluminescence. To estimate the intensity of bioluminescence produced by populations of the heterotrophic dinoflagellates Noctiluca scintillans and Polykrikos kofoidii and autotrophic dinoflagellate Alexandrium mediterraneum in Korean waters, we measured cellular bioluminescence intensity as a function of water temperature and calculated population bioluminescence intensity with cell abundances and water temperature. The mean 200-second-integrated bioluminescence intensity per cell (BLcell) of N. scintillans satiated with the chlorophyte Dunaliella salina decreased continuously with increasing water temperature from 5 to 25℃. However, the BLcell of P. kofoidii satiated with the mixotrophic dinoflagellate Alexandrium minutum continuously increased from 5 to 15℃ but decreased at temperatures exceeding this (to 30℃). Similarly, the BLcell of A. mediterraneum continuously increased from 10 to 20℃ but decreased between 20 and 30℃. The difference between highest and lowest BLcell of N. scintillans, P. kofoidii, and A. mediterraneum at the tested water temperatures was 3.5, 11.8, and 21.0 times, respectively, indicating that water temperature clearly affected BLcell. The highest estimated population bioluminescence intensity (BLpopul) of N. scintillans in Korean waters in 1998-2022 was 4.22 × 1013 relative light unit per liter (RLU L-1), which was 1,850 and 554,000 times greater than that of P. kofoidii and A. mediterraneum, respectively. This indicates that N. scintillans populations produced much brighter bioluminescence in Korean waters than the populations of P. kofoidii or A. mediterraneum.