• Title/Summary/Keyword: BIG KINDS

Search Result 305, Processing Time 0.028 seconds

The Assessment of Ultrasensitive HBsAg kit's Sensitivity level and Performance in Detection of Mutant Forms (Ultra-sensitive HBsAg IRMA 키트의 민감도 및 변이형 검출능 평가)

  • Ha, Dong-Hyuk;Min, Kyung-Sun;Noh, Gyeong-Woon;Kim, Hyun-Ju
    • The Korean Journal of Nuclear Medicine Technology
    • /
    • v.15 no.1
    • /
    • pp.121-125
    • /
    • 2011
  • Purpose: The DNA-type virus HBV, discovered by D. Dane and others in 1976, is approximately 42nm big and known as the main cause of liver-related diseases around the world. HBsAg has 4 kinds of subtypes including adw, adr, ayw and ayr and besides common antigen factor a, there are d, y, r, w. From the methods of serologically testing HBV, IRMA, EIA and CLIa were developed for testing HBsAg and are being used in examining the surface antigen of HBV. In this study, among the methods for testing HBV, the recently developed RIAKEY Ultrasensitive HBsAg IRMA kit's sensitivity level and performance in detection of mutant forms were measured and compared with CLIA. Materials and methods: Two certified reference materials, which are WHO 1st International Standard 1985(80/549) and WHO 2nd International Standard 2003(00/588. subtype adw2, genotypeA), were used in the examination and the sensitivity level was measured by diluting these materials from 0.08 IU/ml to 0.005 IU/ml. The materials for examining the detection of mutant forms included 9 kinds of subtype 'ad' and one kind of subtype 'ay' purchased from DSI company. Also, with the use of positive and negative samples, they was compared with CLIA. Result: Ultrasensitive HBsAg kit based on IRMA method showed the detection of up to 0.01 IU/ml not only for WHO 1st International Standard 1985(80/549) but also for WHO 2nd International Standard 2003(00/588. subtype adw2, genotypeA) and the sensitivity level was measured as 0.01 IU/ml by WHO standard. In testing the performance for detection of mutant forms, the 9 kinds of subtype 'ad' and one kind of subtype 'ay' mutant materials were detected, demonstrating the capacity of detecting various types of mutant forms. Conclusions: With the clinical importance of sensitivity level and performance in detection of mutant forms increasing in the field of HBsAg diagnosis, the examination of IRMA's effectiveness using RIA method in the aspects of the sensitivity level and performance in detection of mutant forms was carried out and its result is as follows. The sensitivity level was measured as 0.01 IU/ml by WHO standard and it was possible to measure various types of mutant forms with high sensitivity. Thus it is suggested that more speedy and accurate reports could be produced from a nuclear medicine laboratory for clinical practitioners requiring results of various situations.

  • PDF

The Study on Compilation Consciousness and Aspect of Personage Adoption of "Ilsayusa" (『일사유사(逸士遺事)』의 편찬 의식과 인물 수록 양상)

  • Cho, Jihyoung
    • (The)Study of the Eastern Classic
    • /
    • no.70
    • /
    • pp.495-524
    • /
    • 2018
  • This study investigated the literary theory of Jang Jiyeon and his compilation consciousness of the historical biography, and based on this, the study examined the aspect and characteristic of the personage adoption of "Ilsayusa". To figure out the characteristic of "Ilsayusa", this study attempted to investigate the Jang Jiyeon's cognition on epic literature first. Jang Jiyeon had interest in the historical biography in his early days. But he clearly expressed the negative position about the novels which had been handed down from old times, mentioning about their harmful effect, even though they were in a big popularity. The good readings he thought was supposed to be helpful for person's work, study, personality and even the custom, so it is thought that the compilation of "Ilsayusa" was planned as a part of a usefulness to help readers' actual lives by summarizing Jang Jiyeon's philosophy as the form of a historical biography of personages who had actually existed. The direct motivation and the awareness of the problem to compile "Ilsayusa" could be confirmed by the postscript he left. Pointing that Joseon's policy of appointing persons of ability resulted in the loss of the nation, Jang Jiyeon paid attention to the classical scholars from low class, people from under middle class and the local figures in Hamgyeongdo and Pyeongando in the process of compiling "Ilsayusa". Along with this, a kind of a sense of duty that the old heritage must be examined by descendents was manifested as the compilation of "Ilsayusa". Through this, Jang Jiyeon tried to show the good model to the readers of "Ilsayusa" what the way of living would be for raising their volition and keeping the fundamentals. The tendency and characteristic of compiling personages in "Ilsayusa" could be sorted in a few ways as written below. First, it includes all kinds of all actually existed episodes while he was collecting various historical biographies published before. Second, it includes the new kinds of personages paying particular attention to figures of middle class and commoners. Third, it compiled the female figures in a great volume and described new model of woman. Fourth, for areas, it has episodes of all areas in the nation including Pyeongando and Hamgyeongdo. Thinking about all the discussion above, we could estimate that "Ilsayusa" is the definitive edition of these kinds of books which inherited all performances of the biographical literature in better way, which had been accomplished in 19th century.

A study on the shape of popular container that the university girl students with different lifestyles are interested in - Focused on basic cosmetic cases - (중국 여대생의 라이프스타일 유형별에 따른 선호 용기 형태디자인 특성에 관한 연구 - 기초화장품을 중심으로 -)

  • Sun, Sheng;Chung, Sung-Whan;Hong, Jung-Pyo;Hyoung, Sung-Eun
    • Science of Emotion and Sensibility
    • /
    • v.11 no.4
    • /
    • pp.531-540
    • /
    • 2008
  • This study, based on the college life style and the courage to make that the purpose of the design process of finding out the correlation. Chinese students study the life style can be categorized into 4 kinds. The courage to top a crowded bottom with a broad form of courage prefer to be brought down, getting smaller and smaller. Regular and relevant inclination stores are independent of trust. 2 as a whole are crowded with smooth curves and the courage to the asymmetric shape is preferred. Active investment, emphasis on foreign languages, tends to prefer shopping on the Internet were related.3 outstanding courage, just a little crowded in the cylindrical form is preferred. Trust the big stores, stores see the taste, his taste for products that are relevant to the tendency of pursuing said. 4, a lot of the colony gradient technique Protruding prefer to be in the form of courage. Home will, that tends to emphasize the brand and design were related. Home will, that tends to emphasize the brand and design were related. To recap the contents of the consumer lifestyle, based on the characteristics of their favorite cosmetics containers vary designs. Different forms, depending on their courage to feel emotions that can see the image. Therefore, the design in courage cosmetics on the characteristics of these granular for consumer research, the granular form of product research and the relationship between the elements in their care are made. The marketing strategy is in the consumer market, but needs more fine-grained analysis methods that can tell people.

  • PDF

Effect of Nano Particles on the Hathcing rate of Artemia sp. Cyst Zooplankton (나노입자가 알테미아(Artemia sp.) Cyst 부화율에 미치는 영향)

  • Jeong, Yeon-Kyu;Lee, Byeong-Woo;Park, Chan-Il;Choi, Kwang-Soo;Kim, Mu-Chan
    • Journal of the Korean Society for Marine Environment & Energy
    • /
    • v.12 no.4
    • /
    • pp.302-306
    • /
    • 2009
  • 9 kinds of nanoparticle used for this study was a particle with the size of less than 100 nm of diameter, and Artemia sp. cyst examined what kind of influence to have upon the process hatched out in nauplius. 82% hatched in nauplius at the opposition ward where a nanoparticle wasn't added after 24 time course. AGZ020, Nano silver, P-25, Sb and SnO nanoparticle showed hatching rate of 18%, 20%, 13%, 50% and 0% respectively by the 20mg/L density, and it became clear that a harmful effect is big, but I had a harmful effect compared with the opposition ward by 75%, 60%, 73% and 73% respectively by Ag-$TiO_2$, In, Sn and Zn nanoparticle, but a feeble thing was known relatively compared with AGZ020, Nano silver, P-25, Sb and SnO nanoparticle. The difference has caused this with the ingredient a nanoparticle has. Ag is included 2 % and AGZ020, Nano silver and P-25 nanoparticle are used widely as anti-fungus agent, and the SnO nanoparticle which became combination is a light catalyst pill, and oxygen is used for a Sn particle. This and others, a possibility that use is generalized and flows into aquatic environment in sequence the home electronics, functionality cosmetics, anti-fungus agent and a light catalyst pill at present becomes high for nanoparticles and others. The anxiety which has an influence on the ecology world in the water with this can be generated, so I'd have to study the potential danger a nanoparticle has continuously.

  • PDF

The Effect of Thatch Decomposing by Application with Composted Liquid Manure and Microorganism Medium in Golf Course Soil (배양미생물과 가축분뇨발효액비의 시비가 골프코스 토양 중 대취분해에 미치는 영향)

  • Ham, Suon Kyu;Lim, Ji Yeon;Lee, Yeong Min
    • Weed & Turfgrass Science
    • /
    • v.3 no.4
    • /
    • pp.342-346
    • /
    • 2014
  • The purpose of this experiment is for investigating how much the amino acid liquid fertilizer and composted liquid manure, culture microorganism effect on the breeding of grasses and knowing the extent of the thatch content through an analysis of the soil. For testing about soil chemical, the quality of grasses, and the extent of the thatch content in the soil, we cultivated 6 kinds of microorganisms having the effect of thatch dissolution and sprayed these 6 microorganisms with composted liquid manure and the amino acid liquid fertilizer on the place Creeping bentgrass have planted. This conduction started from June to October, 2012 and 2013 (The interval: 2 weeks). In the result of the turf growth, there is no big difference between soil chemical and trace element. And we can know Leaf Color Index, Chlorophyll Index and Root Length are almost same as among treatment. In conclusion, the mixing fertilization of culture microorganism and composted liquid manure is better effective than the traditional fertilization. And it can be expected the effect of the quality of grass and Thatch decomposition in soil.

(Development of Ring Core Auto-Classifier by Multi-Motor Control) (여러 개의 모터에 의하여 제어되는 링-코어 자동 선별기 개발)

  • Park, In-Gyu
    • Journal of the Institute of Electronics Engineers of Korea SC
    • /
    • v.39 no.2
    • /
    • pp.104-115
    • /
    • 2002
  • Core is the main component of inductor. This core should be classified into around 10 classes according to the value of inductance and Q. The coil should be winded with the outer-boundary of this core by different number of turns. Theses kind of precise inductors would be required in the future environment which PCs and communication devices demand more high speed and lower voltage level. It would be quite unefficient that only one core is classified once a time. There, it will be developed so that 10 cores are classified simultaneously. For the operation of classifying 10 cores once in a time, suppose 10 test instruments could be used. In this case, it would take much cost since a test instrument Is expensive. So, by using only one test instrument, it is really more desirable that this system is developed. Each core classified by 10 different classes is to be stored into the corresponding box through the corresponding rubber hose. 10 cores are passed on a serial line and are placed on each testing slot. Here, each core located at each slot is tested, and then the bowl located on the top of a step motor is moved into the corresponding spot by rotating step motor with some angles. Each bowl connected with the corresponding box through rubber hose. Actually 100 hoses are connected, 10 step motors are rotated at 10 different angles, so the size is really so big, the shape of connecting 100 hoses is so complicated. Therefore it is anticipated that the system would be going to be easily out of ordered. In this paper the main purpose is to make several suggestions to be able to work well in these kinds of being affected by the abnormal operation of motors and the flow of cores.

Antioxidant and Anticancer Activities of Traditional Kochujang Added with Garlic Porridge (마늘죽 첨가 고추장의 항산화 및 항암효과)

  • Song, Ho-Su;Kim, Young-Mog;Lee, Keun-Tai
    • Journal of Life Science
    • /
    • v.18 no.8
    • /
    • pp.1140-1146
    • /
    • 2008
  • In order to improve the functional properties of kochujang, garic porridge was added to traditional kochujang during manufacturing. Changes in physiochemical properties of kochujang by garic porridge addition were then investigated. No big differences in general chemical compositions was observed between three kinds of kochujangs tested in this study, general kochujang purchased from a market (GK), kochujang added with raw garlic (RGK) and kochujang added with garlic porridge (GPK). However, GPK showed higher level of antioxidant and anticancer activities than those of others. The methanolic extract of GPK showed 66.38% of DPPH radical scavenging activity, while the extracts of GK and RGK exhibited 38.44% and 50.97%, respectively. Also, the effects of three different extracts of kochujangs on cell proliferation of stomach cancer cell (MKN 45), colon cancer cell (HCT116), and lung cancer cell (NCI-H460) were investigated using MTT assay. All of three extracts exhibited the highest anti-proliferative activity against stomach cancer cell, even though the proliferation of colon cancer cell and lung cancer cell were also inhibited. Among them, the extract of GPK showed the highest anti-proliferative activity (62.35%) against stomach cancer cell. From the results obtained in the present study, we concluded that the antioxidant and anticancer activity of GPK mainly originated from garlic because GPK was consisted of 23% garlic (w/w) compared to 10% (w/w) of RGK.

The amendment tendency analysis of the Korean Infectious Disease Prevention Act and a recommendation for the next amendment (전염병관리 관련법령의 변화 추이분석 및 향후 개정방향에 관한 연구)

  • Whang, Chang-Yong;Ohrr, Hee-Choul;Lee, Duk-Hyoung;Park, Ki-Dong;Lee, Jong-Koo
    • Journal of Preventive Medicine and Public Health
    • /
    • v.31 no.3 s.62
    • /
    • pp.540-563
    • /
    • 1998
  • This Study has been carried out to make a recommendation for the next amendment of the Infectious Disease Prevention Act with a specific focus on the kind of notifyable disease. Korean, Japanese, German, U.S, English and French acts on infectious diseases prevention were reviewed, compared with and analized in regards of numbers and kinds of notifyable infectious diseases and their tendency of amendments. An criteria was designed to assess the level of validity of diseases to be designated in the act. Four items, the fatality (greater than 10% or not), the possibility to make a big epidemic, the availability of efficient vaccination and the usefulness of isolation, are used in the assessment. This index is applied to the diseases in Korean and other countries' Infectious Disease Prevention Acts. Results are as follows: 1. The Korean Infectious Disease Preventon Act has a unique way of classifying the notifyable infectious disease, that is, the first, the second and the third class. But the author cannot find the basis of classification. No other countries reviewed have the similar classification. 2. The ten diseases, cholera, plague, yellow fever, diphtheria, typhoid fever, poliomyelitis, rabies, tetanus, malaria, and meningococcal meningitis are designated as the notifyable diseases not only in Korea but also in Japan, Germany, United States, England and france. 3. Thirty seven diseases including small pox, Lassa fever, anthrax, influenza, German measles, Legionellosis, infection with E. coli O157:H7, Q-fever, brucellosis, Lyme disease are designated as legal disease at least one of the above mentioned countries. 4. The Korea has been coped with the change of the infectious disease occurrence for last fifty years in amendment of the Infectious Disease Prevention Act. 5. Japan has a special infectious surveillance system composed of 3,880 clinics throughout the whole country. 6. Germany has classified infectious diseases in five categories which are based on seriousness of disease. Any confirmed death, cases and suspected cases in class I should be reported within 24 hours. But only confirmed death and cases in class II, but not suspected cases, are reportable in Germarny. 7. Plague, bacillary dysentery, pertussis, mumps, Japanese encephaltis and Korean hemorrhagic fevers are diseases with high credits validity index among Korean legal disease. 8. German measles, anthrax, E. coli O157 : H7 infection, Lassa fever, Q-fever, brucellosis are high in validity index among those which are not designated in Korea but designated in other countries. In conclusion, the Korean Infectious Disease Prevention Act has well been coped with the changes of infectious disease occurrence for last fifty years, but the classification basis and the validity of diseases to be designated as legal diseases is worth reevaluating.

  • PDF

A Study on the Effective VTS Communications Analysis by the Method of VCDF in Busan Port (VCDF 방식을 통한 효율적인 VTS 통신 데이터 분석에 관한 연구 - 부산항을 대상으로 -)

  • Kim, Bong-Hyun;Park, Young-Soo
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.22 no.4
    • /
    • pp.311-318
    • /
    • 2016
  • The VTS concept was located as a principal methods of maritime safety administration in world's major harbors and expected to become the pivotal role for the future of the maritime and harbor society with e-Navigation epoch. If recent limelight concept of big-data has been included in aspect of information gathering and analysis with various studies, it's required advanced studies to improve the information analysis capability and application range of the data that can be mining by the VTS. In this study, contrast to other studies that aimed quantitative analysis as communication number, it can be mining the time information and each of the communication VTS for the target vessel, including qualitative analysis, such as the purpose or the type of communication. This comparison across multiple items of the collected information, and presenting the VTS data mining model (VCDF) that can be analyzed for the purpose of analyzing way, type and number of communication by ship's type, also number of violations through VTS communication. First, In Busan port case, it shows frequently information service and shows frequently communicating with particular types of vessels. Second, Passive VTS carried out notwithstanding many kinds of traffic violations due to communication congestion. This arranged information can be used as data for the analysis, as possible the level of traffic for VTSO situational awareness, which pointed to the 'workloads' in 'IALA Guideline' and could be used as a database for future research of e-Navigation.

A Study on the Buckling Strength of Perforated Plates for 60M Twin-hull Car-ferry (60M급 쌍동형 카페리 구조의 유공판 좌굴강도 연구)

  • Seo, Kwang-Cheol;Oh, Jungmo
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.24 no.1
    • /
    • pp.126-132
    • /
    • 2018
  • This paper discusses about results of advanced buckling strength design for several kinds of perforated plated in the twin-hull car-ferry. For medium / small sized high speed vessels with a length of more than 50 meters and a length / width ratio of more than 12, such as car-ferries, it is highly possible that the buckling strength becomes weak due to the relatively thin thickness and the use of low strength capacity such as mild steel. Especially, it becomes big problem about weak buckling rigidity around the opening to access purpose in the perforated. As regarding safety design point of view for perforated plate, it is necessary to clarify buckling strength and ultimate strength by the distribution of in-plane load distribution around the opening. In this study, nonlinear series analysis using ANSYS was performed to clarify the influence of parameters such as aspect ratio, opening ratio and opening shape affecting the buckling and ultimate strength characteristics of the perforated plate under axial compression and we are derived the optimum design as buckling strength point of view. Based on these results, the governing factor determining the buckling strength of the perforated plate was the opening ratio, and the aspect ratio and the shape of the hole were not influenced.