• 제목/요약/키워드: BE0623

검색결과 4건 처리시간 0.013초

Properties of BE0623 to serve as a growth factor of Bifidobacterium

  • Cho, Young Hoon;Sim, Jae Young;Nam, Myoung Soo
    • 농업과학연구
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    • 제47권3호
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    • pp.445-457
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    • 2020
  • Prebiotics are defined as "Nondigestible food ingredients that beneficially affect the host by selectively stimulating the growth and activity of bacteria in the intestine" and as defined improve host health. This study was carried out to investigate the effects of bifidobacteria (Bifidobacterium lactis BB12 and Bifidobacterium longum BB536) growth enhancer (BE0623) supplement as a prebiotic. The addition of BE0623, a growth promoting material for bifidobacteria, significantly increased bifidobacteria viable cells counts in fermented milk by about 45 to 75 times compared to the non-added control group. In addition, microscopic observation showed a significant effect on proliferation of bifidobacteria in fermented milk with added BE0623. The viable cell counts in bifidobacteria also increased roughly 102-fold compared to the control group (non-added BE0623) and was higher than that of commercial growth promoters. Each fraction obtained though the purification of BE0623 influenced the increase of bifidobacteria growth. Culturing bifidobacteria with a combination of fractions of BE0623 had a synergistic effect compared to culturing bifidobacteria with each fraction individually. When any of the fractions were not added, the effect of the growth enhancer on bifidobacteria was reduced. These results indicate that all fractions contain substances that promote the growth of bifidobacteria. Therefore, BE0623 is considered to be available as a growth promoting material for bifidobacterium.

Effect of yoghurt with a Bifidobacteria enhancer and dietary fiber on irritable bowel syndrome

  • Cho, Young Hoon;Bae, Hyoung Churl;Nam, Myoung Soo
    • 농업과학연구
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    • 제48권3호
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    • pp.575-587
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    • 2021
  • This study was carried out to investigate the effects of supplementation with a Bifidobacteria enhanced yogurt (BE0623 yogurt), which includes Bifidobacterium lactis BB12, Lactobacillus acidophilus, Streptococcus thermophilus, and Bifidobacterium lactis, in the management of irritable bowel syndrome (IBS) using animal models and clinical trials. In a rat study, a loperamide-treated group (LOP) showed reduced water content in fecal pellets but showed an increased number of fecal pellets in the distal colon. In addition, the BE0623 yogurt (L-BE0623Y) group had the fewest fecal pellets in the distal colon. Regarding the serum lipid parameters, the LOP group had a high-density lipoprotein (HDL)/total cholesterol ratio that was 43% lower than that of a normal water group (NOR), but the outcome for the L-BE0623Y group was 27% lower than the NOR group. In a human study, 116 adults with IBS were sampled as subjects and fed 300 mL of yogurt per day for an eight week period. There was an IBS improvement in the L-BE0623Y and commercial yogurt (L-CY) groups, though flatulence, stool consistency and frequency of defecation outcomes were also noted. Specifically, the L-BE0623Y treatment group showed significant effects with regard to defecation duration and urgency after the consumption of the yogurt used in this study. These results suggest that the Bifidobacteria-enhanced yogurt has superior effects with regard to relieving loperamide-induced constipation in rats and that regular consumption of L-BE0623Y is effective to improve IBS in humans.

Characteristics of fermented milk containing Bifidobacterium growth promoter (BE0623) and dietary fiber

  • Cho, Young Hoon;Sim, Jae Young;Nam, Myoung Soo
    • 농업과학연구
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    • 제48권2호
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    • pp.209-218
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    • 2021
  • This study was carried out to investigate the effects of Bifidobacteria growth promoter BE0623 and a dietary fiber supplement, which included Bifidobacterium lactis BB12, Lactobacillus acidophilus, Streptococcus thermophilus, and Bifidobacterium lactis. In fermented milk containing BE0623, the viable cell count of Bifidobacteria significantly increased by about 45 to 75 times compared to the control, and the titratable acidity increased, whereas the pH decreased. All fractions obtained by isolating BE0623 had Bifidobacteria growth effect. Acacia dietary fiber is a pale yellow powder. It has a viscosity of 60 to 100 cPs and a pH between 4.1 and 5.0. Its general components are less than 10% moisture, more than 90% dietary fiber, and less than 4% ash. The optimal addition ratio of Bifidobacteria growth promoting material was determined to be 0.05%. The general components of the manufactured fermented milk were carbohydrate 17.85%, protein 3.63%, fat 3.00%, and dietary fiber 2.95%. During storage of the fermented milk for 24 days, its titratable acidity, viscosity, and sugar content all met the criteria. In addition, the viable cell counts of Bifidobacteria and lactic acid bacteria in the fermented milk were 1.7 × 108 CFU·mL-1 and 1.5 × 107 CFU·mL-1, respectively, and Escherichia coli was negative. There was no significant difference between the control group and the treatment group in the sensory evaluation of sweet, sour, weight, and flavor, and the preference for the treatment group was excellent. The acceptability of the fermented milk of the treated group according to the storage period was excellent in terms of color, flavor, and appearance.

국내 건설기업의 아시아 계약실적 구조 분석 (Analyzing the Market Structure of Asian Construction Contracts : A Perspective on Korean Construction Firms)

  • 이강욱
    • 대한토목학회논문집
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    • 제39권5호
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    • pp.623-630
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    • 2019
  • 아시아 건설시장의 전략적 중요성이 높아지면서 기업 간 경쟁이 더욱 치열해지고 있다. 기존의 아시아 건설시장에 대한 연구는 주요 국가로의 진출전략 도출, 분야별 리스크 평가에 대한 정성적 접근이 주류를 이루었던 반면, 다수 기업의 역동적인 경쟁구도를 정량적으로 설명한 연구는 드물었다. 이에 본 연구는 국내 건설기업이 2009년부터 2017년까지 계약을 체결한 3,996건의 프로젝트 정보를 바탕으로 아시아 지역의 계약실적 구조를 분석하였다. 정태적 분석에는 시장 집중도, 동태적 분석에는 시장 이동성 및 불안정성 개념을 각각 활용하였으며, 이에 대한 수학적 모델을 소개하였다. 분석 결과, 정태적 측면에서는 아시아 건설시장에서 국내 상위 기업군의 시장 점유율 집중 현상이 나타나고 있으며, 동태적 측면에서는 산업설비 공종을 제외한 대부분의 경우 시장 지위가 약하고 안정성이 떨어지는 것으로 밝혀졌다. 본 연구에서 제시한 분석 방법론과 결과는 산업 차원의 실적에 대한 체계적 진단을 가능케 하며, 향후 경쟁전략 수립을 위한 기초자료를 제공하였다는 점에서 의의가 있다.