• Title/Summary/Keyword: BCR

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A study on the food clean room system observing the regulations of HACCP (HACCP의 환경 최적화를 위한 식품 클린룸 설계에 관한 연구)

  • Won, Young-Jae;Suh, Kee-Won
    • Proceedings of the SAREK Conference
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    • 2009.06a
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    • pp.520-526
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    • 2009
  • This study proposed the optimum design values for the biological clean room system observing the regulations of Hazard Analysis Critical Control Point (HACCP). Even though the standard for industrial clean room system has been well established, the basis for biological food clean room system is the first stage. In order to prevent the contaminations in advance for food storages, processes, and distributions, the criterion of Hazard Analysis Critical Control Point is positively required. This study also suggested the possible ways of how to avoid the hazardous contaminations.

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HACCP의 환경 최적화를 위한 식품 클린룸 설계에 관한 연구

  • Won, Yeong-Jae
    • Air Cleaning Technology
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    • v.23 no.3
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    • pp.1-9
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    • 2010
  • This study proposed the optimum design values for the biological clean room system observing the regulations of Hazard Analysis Critical Control Point (HACCP). Even though the standard for industrial clean room system has been well established, the basis for biological food clean room system is the first stage. In order to prevent the contaminations in advance for food storages, processes, and distributions, the criterion of Hazard Analysis Critical Control Point is positively required. This study also suggested the possible ways of how to avoid the hazardous contaminations.

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A study on bus voltage stabilization of PCU (Power Control Unit) for GEO (Geosynchorous Earth Orbit) satellite (정지궤도위성용 전력제어 조절기의 버스전압 안정화에 관한 연구)

  • Choe, Hyun-Su;Gil, Yong-Man;Ahn, Tae-Young;Yoo, Seung-Hee;Woo, Hyuk-Jae;Pack, Sung-Woo;Koo, Ja-Chun
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.946-947
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    • 2015
  • 정지궤도 복합위성용 전력조절장치는 위성의 전력버스에 필요한 전력을 조절하고 배터리의 충전과 방전을 제어하고 관리한다. 전력조절장치의 용량은 1kw로 하고 태양 전지의 어레이는 4개의 패널로 구성되며 S3R(Sequential Switching Shunt Regulator)을 이용하여 조절된 버스전압은 완전조절 50Vdc으로 한다. 변환된 전력은 위성부하에 필요한 전력을 분배하는 PDM(Power Distribution Module)에 공급된다. 남은 전력은 BCR(Battery Charge Regulator)를 통해 배터리에 전력을 충전하고 전력이 부족할 때 BDR(Battery Discharge Regulator)를 통해 방전을 하여 버스전압에 전력을 공급한다.

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Chemical kinomics: a powerful strategy for target deconvolution

  • Kim, Do-Hee;Sim, Tae-Bo
    • BMB Reports
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    • v.43 no.11
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    • pp.711-719
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    • 2010
  • Kinomics is an emerging and promising approach for deciphering kinomes. Chemical kinomics is a discipline of chemical genomics that is also referred to as "chemogenomics", which is derived from chemistry and biology. Chemical kinomics has become a powerful approach to decipher complicated phosphorylation-based cellular signaling networks with the aid of small molecules that modulate kinase functions. Moreover, chemical kinomics has played a pivotal role in the field of kinase drug discovery as it enables identification of new molecular targets of small molecule kinase modulators and/or exploitation of novel functions of known kinases and has also provided novel chemical entities as hit/lead compounds. In this short review, contemporary chemical kinomics technologies such as activity-based protein profiling, T7 kinasetagged phages, kinobeads, three-hybrid systems, fluorescenttagged kinase binding assays, and chemical genomic profiling are discussed along with a novel allosteric Bcr-Abl kinase inhibitor (GNF-2/GNF-5) as a successful application of chemical kinomics approaches.

Analysis on Renewable Energy Aid to North Korea (AHP 방법론을 이용한 대북지원 최적 신재생에너지원 선정 연구)

  • Yi, Sul-Ki;Sin, Hwa-Young;Kim, Ji-Hyo;Heo, Eun-Nyeong
    • 한국신재생에너지학회:학술대회논문집
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    • 2009.11a
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    • pp.293-296
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    • 2009
  • 지속가능한 대북 에너지 지원체제 정립을 위한 논의의 일환으로서 대북지원 최적 신재생에너지원을 선정하기 위하여 AHP 방법론을 이용한 분석을 수행하였다. BCR을 이용하여 속성을 구성하였으며, 정책전문가, 기술전문가, 외국인 및 내국인 등 15인의 전문가들을 대상으로 설문조사를 실시하였다. 분석 결과 풍력에너지가 가장 적합한 에너지원이라는 결론이 도출되었다. 또한 응답자들의 특징에 따라 그룹을 설정하여 분석한 결과 기술전문가들은 태양열에너지를, 정책전문가들은 풍력에너지를 최적의 대안으로 평가했으며, 정책전문가들 중 국내 전문가들은 소수력에너지, 국외 전문가들은 풍력에너지가 최적 대안인 것으로 평가하였다.

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Dehydriding Kinetics of the Mg2NiHx by Isothermal Thermogravimetry Analysis (등온 열중량 분석에 의한 Mg2NiHx 탈수소화 반응속도 연구)

  • Hong, Tae Whan;Kim, Young Jig
    • Transactions of the Korean hydrogen and new energy society
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    • v.11 no.1
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    • pp.11-18
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    • 2000
  • In order to investigate the dehydriding properties of the $Mg_2NiH_x$ formed by hydrogen induced mechanical alloying, we performed isothermal thermogravimetry analysis at 453, 463, 473, 483, 493, 503 and 513K for 1 hours. Dehydrogenation kinetics were dependant strongly on the MA conditions which determine the In other words, kinds of synthesized hydrides phases and the crystal microstructures. The MA condition, 66:1 BCR(balls to chips mass ratio), especially 96h milling time, revealed the hydride phases of nano-/ amorphous state and the dehydriding activation energy of $43.4{\pm}3.6kJ/mole$.

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An Analysis on the Economic Validity of the Establishment of R&D Supreme Academy (R&D 인력 재교육 전문기관의 경제적 타당성 분석)

  • Lim, Chang-Joo;Kim, Sang-Yung;Baek, Nak-Ki;Oh, Sea-Hong;Seo, Jong-Hyen
    • Journal of the Korea Safety Management & Science
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    • v.11 no.3
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    • pp.181-188
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    • 2009
  • This paper presents the economic validity with the cost/benefit analysis on establishing R&D Supreme Academy. To evaluate the profitability of R&D Supreme Academy, willingness to pay (WTP) is measured by contingent valuation method (CVM) and then the net present value (NPV), internal rate of return (IRR) and benefit/cost ratio(BCR) are calculated. The results of economic evaluation verified that the establishment of R&D Supreme Academy is timely and effective in an economic perspective.

Specific Cell-Signal Targets for Cancer Chemotherapy

  • Aszalos, Adorjan
    • Archives of Pharmacal Research
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    • v.25 no.1
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    • pp.1-10
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    • 2002
  • Attempts to develop drugs, specific for cancer cells, are dealt here according to the intended cell-target. While many target specific drugs were developed, they reach only moderate successes in clinics for reasons, such as, delivery problem, lack of in vivo efficacy or toxicity. However, recent efforts focusing on the diversity of tyrosine kinases, participating in cell-signal transduction, brought fruit. The first such drug, Givec, approved by the USFDA recently, is used in clinics with great success to threat CML. The drug inhibits tyrosin kinase of bcr-abl, c-abl and v-abl. Work is progressing on other tyrosin kinase inhibitors and on other type of specific cancer cell signal protein inhibitors. These efforts are hoped to yield better cures for cancer in the near future.

A Prediction Model on DC Distribution using Scenario Analysis (시나리오 분석을 통한 DC 배전시장 예측 모델의 적용)

  • Yeo, Seo-Hyun;Sun, Hwi-il;Park, Jin-Wook;Yoo, Dong-Wook;Song, Sung-Geun;Park, Sung-Jun
    • Proceedings of the KIPE Conference
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    • 2017.07a
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    • pp.475-476
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    • 2017
  • 본 논문은 다수의 국외 시장 전망 보고서를 기반으로 최근 해외 도입 및 국내 구축 예정인 DC 배전 시장 동향과 경제적 효율성을 분석하였다. 분석 방법은 3가지 시나리오에 따라 2030년까지의 시장 규모 추이를 예측하고, DC 배전을 구성하는 배전용 전력기기의 시장 규모를 도출하였다. 또한 시장점유율, 부가가치율, 온실가스 감축 등의 요소를 적용하여, 세계 시장에 대한 국내 기업 점유율에 따른 DC 배전의 편익을 계산하였다. 그 결과 2030년 기준 DC 배전 시장 규모의 긍정적 확장성을 예측할 수 있었으며, DC 배전용 전력기기 시장 규모와 이에 따른 경제적 편익을 확인하였다. 추후 연구에서는 DC 배전 시장을 구성하는 각 부문들의 규모 추이를 파악하고, 국내 DC 배전용 전력기기 개발 실데이터를 적용하여 비용편익비(BCR)를 도출하고자 한다.

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Antipruritic Effect of Black Colored Rice

  • Han, Sang-Jun;Trinh, Hien Trung;Hong, Seong-Sig;Ryu, Su-Noh;Kim, Dong-Hyun
    • Natural Product Sciences
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    • v.13 no.4
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    • pp.373-377
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    • 2007
  • Antiscratching behavioral effects of the water extract of two black colored rice (BCR) varieties [Oryza sativa L. cv. Heugjinjubyeo (HJ) and Josaengheugchalbyeo (JH)], major pigment of which is cyanindin 3-glucoside, were investigated. Orally administered BCRs' extracts exhibited potent inhibitory activity against scratching behaviors which were induced by compound 48/80 and histamine. The inhibitory effect of Josaengheugchalbyeo in vivo and in vitro were more potent than those of Heugjinjubyeo. These finding suggest that black colored rice, especially Josaengheugchalbyeo, may inhibit scratching behaviors and anaphylaxis reaction by stabilizing membrane.