• 한국전산구조공학회논문집
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• 제24권4호
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• pp.449-455
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• 2011

최근 가압중수형 원전 격납건물의 내압능력 및 비선형 거동에 관한 실증실험과 해석코드에 대한 검증을 위하여 인도의 BARC 주관으로 가압중수형 격납건물 1/4 축소모델을 건설하였고, 내압성능평가를 위한 국제공동연구가 수행되었다. 이 논문은 가압중수형 1/4 축소모델 격납건물에 대한 내압성능과 비선형 거동을 예측하기 위하여 유한요소해석을 수행하였고 그 결과를 도출하였다. 대상 격납건물은 기초매트와 원통형 벽체 및 돔으로 구성되어 있고, 수평 텐던의 정착을 위하여 4개의 부벽(buttress)을 가지고 있다. 유한요소해석을 위하여 ABAQUS를 이용하였고 콘크리트, 철근 및 텐던에 대한 유한요소 모델을 작성하여 극한내압해석을 수행하였다. 유한요소해석결과 콘크리트의 초기 균열은 $1.6P_d$(design pressure)에서 발생하였고, 철근의 항복은 $3.36P_d$ 그리고 극한내압능력은 $4.0P_d$ 수준으로 나타났다.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2007년도 춘계학술발표회 초록집
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• pp.71-72
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• 2007

In this study, we investigated the fabrication of MLR (multi-layer resist) with a very thin diamond-like carbon (DLC) layer. ArF PR/$SiO_2$/DLC MLR structure was investigated and etching characteristics of the DLC layer was patterned using $SiO_2$ hard-mask by varying the process parameters such as different high-frequency/low-frequency combination ($f_{LF}/f_{HF}$), HF/LF power ratio ($P_{HF}/P_{LF}$), $O_2$ flow and $N_2$ flow rate in $O_2/N_2$/Ar plasmas. The results indicated an increased etch rate of DLC for the higher $f_{LF}/f_{HF}$ combination and for the increased low-frequency power ($P_{LF}$). And the etch rate of DLC was decreased with increasing the $N_2$ flow rate in $O_2/N_2$/Ar plasmas. In order to confirm the application of DLC MLR for the etching process of silicon oxide, the stack of ArF PR/BARC/$SiO_2$/DLC/TEOS/Si was investigated.

• Journal of Plant Biotechnology
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• 제49권1호
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• pp.61-73
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• 2022

In this study, we developed a reliable and efficient Agrobacterium-mediated genetic transformation system by applying sonication and vacuum infiltration to six chickpea cultivars (ICCV2, ICCV10, ICCV92944, ICCV37, JAKI9218, and JG11) using embryo axis explants. Wounded explants were precultured for 3 days in shoot induction medium (SIM) before sonication and vacuum infiltration with an Agrobacterium suspension and co-cultivated for 3 days in co-cultivation medium containing 100 µM/l of acetosyringone and 200 mg/l of L-cysteine. Responsive explants with putatively transformed shoots were selected using a gradual increase in kanamycin from 25 mg/l to 100 mg/l in selection medium to eliminate escapes. Results showed optimal transformation efficiency at a bacterial density of 1.0, an optical density at 600 nm wavelength (OD₆₀₀), and an infection duration of 30 min. The presence and stable integration of the β-glucuronidase (gusA) gene into the chickpea genome were confirmed using GUS histochemical assay and polymerase chain reaction. A high transformation efficiency was achieved among the different factors tested using embryo axis explants of cv. JAKI 9218. Of the six chickpea cultivars tested, JAKI9218 showed the highest transformation efficiency of 8.6%, followed by JG11 (7.2%), ICCV92944 (6.8%), ICCV37 (5.4%), ICCV2 (4.8%), and ICCV10 (4.6%). These findings showed that the Agrobacterium-mediated genetic transformation system will help transfer novel candidate genes into chickpea.

• Wind and Structures
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• 제34권1호
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• pp.59-72
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• 2022

In this work the numerical results of the flow around a 5:1 rectangular cylinder at Reynolds numbers 3 000 and 40 000, zero angle of attack and smooth incoming flow condition are presented. Implicit Large Eddy Simulations (ILES) have been performed with a high-order accurate spatial scheme and an implicit high-order accurate time integration method. The spatial approximation is based on a discontinuous Galerkin (dG) method, while the time integration exploits a linearly-implicit Rosenbrock-type Runge-Kutta scheme. The aim of this work is to show the feasibility of high-fidelity flow simulations with a moderate number of DOFs and large time step sizes. Moreover, the effect of different parameters, i.e., dimension of the computational domain, mesh type, grid resolution, boundary conditions, time step size and polynomial approximation, on the results accuracy is investigated. Our best dG result at Re=3 000 perfectly agrees with a reference DNS obtained using Nek5000 and about 40 times more degrees of freedom. The Re=40 000 computations, which are strongly under-resolved, show a reasonable correspondence with the experimental data of Mannini et al. (2017) and the LES of Zhang and Xu (2020).

• Wind and Structures
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• 제34권1호
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• pp.15-27
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• 2022

This work comes within the framework of the "Benchmark on the Aerodynamics of a Rectangular Cylinder" that investigates a rectangular cylinder of length-to-depth ratio equal to 5. The present study reports and discusses velocity fields acquired using planar Particle Image Velocitmetry for several angles of attack and Reynolds numbers. In particular, for a cylinder depth-based Reynolds number of 2 × 10⁴ and zero incidence angle, the flow features along the lateral (parallel to the freestream) upper and lower surfaces of the cylinder are reported. Using first and second order statistics of the velocity field, the main flow features are discussed, especially the size and location of the time-averaged flow structures and the distribution of the Reynolds stresses. The variation of the flow features with the incidence is also studied considering angles of attack up to 6°. It is shown that the time-averaged flow is fully detached for incidence higher than 2°. For an angle of attack of 0°, the effects of the Reynolds number varying between 5 × 10³ and 2 × 10⁴ are investigated looking at flow statistics. It is shown that the time-averaged location of the reattachment point and the shape and position of the time-averaged main vortex are mostly constant with the Reynolds number. However, the size of the inner region located below the time-averaged shear layer and just downstream the leading edge corner appears to be strongly dependent on the Reynolds number.

• Korean Circulation Journal
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• 제54권4호
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• pp.189-200
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• 2024

Background and Objectives: Concerns remain that early aspirin cessation may be associated with potential harm in subsets at high risk of ischemic events. This study aimed to assess the effects of P2Y12 inhibitor monotherapy after 3-month dual antiplatelet therapy (DAPT) vs. prolonged DAPT (12-month or longer) based on the ischemic risk stratification, the CHADS-P2A2RC, after percutaneous coronary intervention (PCI). Methods: This was a sub-study of the SMART-CHOICE trial. The effect of the randomized antiplatelet strategies was assessed across 3 CHADS-P2A2RC risk score categories. The primary outcome was a major adverse cardiac and cerebral event (MACCE), a composite of all-cause death, myocardial infarction, or stroke. Results: Up to 3 years, the high CHADS-P2A2RC risk score group had the highest incidence of MACCE (105 [12.1%], adjusted hazard ratio [HR], 2.927; 95% confidence interval [CI], 1.358-6.309; p=0.006) followed by moderate-risk (40 [1.4%], adjusted HR, 1.786; 95% CI, 0.868-3.674; p=0.115) and low-risk (9 [0.5%], reference). In secondary analyses, P2Y12 inhibitor monotherapy reduced the Bleeding Academic Research Consortium (BARC) types 2, 3, or 5 bleeding without increasing the risk of MACCE as compared with prolonged DAPT across the 3 CHADS-P2A2RC risk strata without significant interaction term (interaction p for MACCE=0.705 and interaction p for BARC types 2, 3, or 5 bleeding=0.055). Conclusions: The CHADS-P2A2RC risk score is valuable in discriminating high-ischemic-risk patients. Even in such patients with a high risk of ischemic events, P2Y12 inhibitor monotherapy was associated with a lower incidence of bleeding without increased risk of ischemic events compared with prolonged DAPT.

• Journal of Forest and Environmental Science
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• 제36권3호
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• pp.207-218
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• 2020

Ashwagandha is an important ancient medicinal crops, being affected with many diseases, among which leaf blight caused by Alternaria alternata has become the constraint resulting in huge yield losses. Continuous usage of chemical methods leads to environment, soil and water pollution. Whereas biological control of diseases is long lasting, inexpensive, eco-friendly and harmless to target organisms. In this context, it is aimed to evaluate five Trichoderma strains viz. Trichoderma virens IMI-392430, T. pseudokoningii IMI-392431, T. harzianum IMI-392432, T. harzianum IMI-392433 and T. harzianum IMI-392434 as bio-control efficacy against A. alternata and growth promoting effect in Ashwagandha. All the Trichoderma strains had varied antagonistic effects against the pathogen. In dual culture technique, the strain T. harzianum IMI-392433 showed maximum percentage inhibition of mycelial growth (54.89%) followed by T. harzianum IMI-392432 (53.83%), T. harzianum IMI-392434 (48.94%) and T. virens IMI-392430, (43.62%) against the pathogen, while the least inhibition percentage was observed with the T. pseudokoningii IMI-392431 (36.60%). The culture filtrate of the Trichoderma strain, T. harzianum IMI-392433 recorded highest inhibition on the mycelial growth (39.05%) and spore germination (80.77%) of pathogen and the lowest was recorded in T. pseudokoningii IMI-392431 (20.45 and 50%). Moreover, seeds treated with spore suspension of the strain T. harzianum IMI-392433 reduced the percentages of disease severity index significantly. The strain T. harzianum IMI-392433 also significantly increased seed germination %, seedling vigor and growth of Ashwagandha. The correlation matrix showed that root yield per plant of Ashwagandha had significant and positive correlation with plant height (r=0.726^⁎⁎), number of leaf (r=0.514^⁎⁎), number of primary branch (r=0.820^⁎⁎), number of secondary branch (r=0.829^⁎⁎), fresh plant weight (r=0.887^⁎⁎), plant dry weight (r=0.613^⁎⁎), root length (r=0.824^⁎⁎), root diameter (r=0.786^⁎⁎), root dry weight (r=0.739^⁎⁎) and fresh root weight (r=0.731^⁎⁎). The significant and negative correlation (r=-0.336^⁎⁎) was observed with the root yield and percentages of disease severity index. The study recognized that the T. harzianum IMI-392433 strain performed well in inhibiting the mycelial growth and reduced the percentages of disease severity index of pathogen as well as increased the plant growth in Ashwagandha.

• 대한핵의학회지
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• 제25권1호
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• pp.46-52
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• 1991

Radioaerosol inhalation imaging (RII) has been used in radionuclide pulmonary studies for the past 20 years. The method is well accepted for assessing regional ventilation because of its usefulness, easy fabrication and simple application system. To evaluate its clinical utility in the study of impaired regional ventilation in bronchial asthma, we obtained and analysed RIIs in 31 patients (16 women and 15 men; age ranging 21-76 years) with typical bronchial asthma at the Department of Radiology, Kangnam St. Mary's Hospital, Catholic University Medical college, from January, 1988 to August, 1989. Scintiscans were obtained with radioaerosol produced by a BARC(Bhabha Atomic Reserch Center, India) nebulizer with 15 mCi of $^{99m}Tc-phytate$. The scanning was peformed in anterior, posterior and lateral projections following 5-minute inhalation of radioaerosol on sitting position. The scans were analyzed and correlated with the results of pulmonary function study and the findings of chest radiography. Fifteen patients had concomitant lung perfusion image with $^{99m}Tc-MAA$. Follow-up scans were obtained in 5 patients after bronchodilator therapy. The patients were divided into (1) attack type (4 patients), (2) resistant type (5 patients), (3) remittent type (10 patients) and (4) bronchitic type (12 patients). Chest radiography showed hyperinflation, altered pulmonary vascularity, thickening of the bronchial wall and accentuation of basal interstitial markings in 26 of the 31 patients. Chest radiographs were norma! in the remaining 5 patients. Regardless of type, the findings of RII were basically the same, and characterized by the deposition of radioaerosol in the central parts or in the main respiratory air ways along with mottled nonsegmental ventilation defects in the periphery. Peripheral parenchymal defects were more extensive than that of expected findings from clinical symptoms, pulmonary function test and chest radiograph. Broomstick sign was present in 17 patients. The abnormality of RII was poorly correlated with perfusion scans. In all 5 patients treated with bronchodilators, follow-up study demonstrated a decrease in the degree of radioaerosol deposition in the central air way with improved ventilation defects. This study indicates that RII is a useful technique for the evaluation of regional ventilation abnormality and the effect of treatment with bronchodilators in patients with bronchial asthma.

• 대한핵의학회지
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• 제24권2호
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• pp.229-236
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• 1990

Perfusion and ventilaion imagings of the lung are well established procedure for diagnosing pulmonary embolism, differentiation it from chronic obstructive lung disease, and making an early detection of chronic obstructive lung disease. To evaluate the usefulness of radioaerosol inhalation imaging (RII) in chronic obstructive lung disease, especially pulmonary emphysema, we analyzed RIIs of five normal adult non-smokers, five asymptomatic smokers (age 25-42 years with the mean 36), and 21 patients with pulmonry emphysema (age 59-78 years with the mean 67). Scintigrams were obtained with radioaerosol produced by a BARC nebulizer with 15 mCi of Tc-99m-phytate. Scanning was performed in the anterior, posterior, and lateral projections after five to 10-minute inhalation of the radioaerosol on sitting position. The scans were analyzed and correlated with the results of pulmonary function studies and chest radiographs. Also lung perfusion scan with $^{99m}Tc-MAA$ was performed in 12 patients. In five patients, we performed follow-up scans for the evaluation of the effects of a bronchodilator. Based on the X-ray findings and clinical symptoms, pulmonary emphysema was classified into four types: centrilobular (3 patients), panlobular (4 patients), intermediate (10 patients), and combined (4 patients). RII findings were patternized according to the type, extent, and intensity of the aerosol deposition in the central bronchial and bronchopulmonary system and lung parenchyma. 10 controls, normal five non-smokers and three asymptomatic smokers revealed homogeneous parenchymal deposition in the entire lung fields without central bronchial deposition. The remaining two of asymptomatic smokers revealed mild central airway deposition. The great majority of the patients showed either central (9/21) or combined type (10/21) of bronchopulmonary deposition and the remaining two patients peripheral bronchopulmonary deposition. Parenchymal aerosol deposition in pulmonary emphysema was diffuse (6/21), discrete(6/21), intermediate (3/21), or combined (6/21). In 12 patients studied also with perfusion scans, perfusion defects matched closely with ventilation defects in location and configuration. But the size of the ventilation defects was generally larger than the perfusion defects. In all four patients treated with bronchodilators, the follow-up study demonstrated decrease in abnormal of radioaerosol deposition in the central airway with improvement of ventilation defects. RII was useful technique for the evaluation of regional ventilatory abnormality and the effects of treatment with bronchodilators in pulmonary emphysema.

• 농업과학연구
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• 제35권1호
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• pp.85-100
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• 2008

미국 농무성은 방글라데시의 Pirganj군과 Kurigram군에 작물재배기술을 보급하여 농민들의 소득을 향상시키고 작물의 수량을 제고하여 농민들의 식량을 자급 할 수 있도록 하기 위하여 2008년부터 2012년까지 4개년간 기술지원기금US$ 571,270을 제공할 계획이다. 이 사업의 주목적은 948ha, 임야개간 52ha 및 유휴지 345ha를 개발하고 농업생산기술을 지도 보급함으로써 농산물의 생산성을 제고시키고 가난한 1,059농가와 5,305명의 농촌농민들의 사회 경제적 생활조건을 개선시키는 것이다. 이 사업을 위하여 방글라데시의 미작연구소, 방글라데시 농업연구위원회, Rangpur Dinajpur 농촌 서비스 센터 및 농민단체들이 참여 하고 있다. 본 연구의 목적은 (1) 미곡, 밀, 옥수수, 엽연초 및 사탕수수의 생산성을 구명하고, (2) 작물 별 생산비와 소득을 추정하며, (3) 투입 산출물간의 상호관계를 구명하여 (3) 본 사업의 총 수익과 총 사업비를 비교함으로써 본 사업의 재무적 타당성 지표인 FIRR,NPV,B/C Ratio를 구명해 보고자 한다. 본 사업의 연간 순기대총편익은 US$ 33,028이다. 농산물 생산액의 총 증가액은 US$ 219,959이며 총 생산비증가액은 US$186,931로 추정되었다. 본 사업의 재무수익률은 경제분석기간을 15년으로 가정했을 경우 재무수익률(FIRR)이 26.15%로 추정되었으며, 이는 방글라데시의 할인율 10%보다 2.6배가 높게 나타났다. 방글라데시의 할인율을 10%로 볼 경우 B/C Ratio는 1.077이며 NPV는 US$ 101,663로 추정되었다. 따라서 본 사업은 방글라데시의 농촌경제를 활성화 시키고 가난한 농민들의 복지를 증대시키는데 있어 매우 중요한 농업정책으로써, 방글라데시의 타 지역에도 확대 보급함은 물론 재정적 지원을 지속해 나가야 할 것으로 판단된다.