• Toxicological Research
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• v.18 no.4
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• pp.363-367
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• 2002

Reactive of gen species (ROS) contribute to several cellular function and are involved in the regulation of signal transduction, gene expression, and proliferation. In the present study, we investigated the effect of $H_2O_2$ treatment on IgM secretion in LPS-stimulated murine B Iymphoma, CH12.LX. Cells were treated directly With $H_2O_2$ and stimulated with LPS. $H_2O_2$ treatment during 72 h time period inhibited IgM secretion in LPS-stimulated CH12.LX cells in a dose- and time-dependent manners. After treatment with 50 $\mu\textrm{M}$ $H_2O_2$ during 72 h time period, the level of IgM in LPS-stimulated CH12.LX cells was markedly decreased, whereas cell viability was not significantly changed. Addition of $H_2O_2$ concomitantly with LPS, or 12 h post-LPS stimulation, produced a significant inhibition of IgM secretion, Whereas inhibitory effect of $H_2O_2$ on IgM secretion was not observed when added 24 h after LPS stimulation. These findings suggest that $H_2O_2$ can inhibit the secretion of IgM in LPS-stimulated CH15.LX cells, and may alter the events necessary for terminal B cell differentiation.

• Food Engineering Progress
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• v.21 no.1
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• pp.88-92
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• 2017

We attempted to investigate antibacterial and proteolytic activities of bacteria isolated from three ethnic fermented seafoods in the east coast of South Korea, gajami sikhae, squid jeotgal, and fermented jinuari (Grateloupia filicina). Bacillus cereus ATCC 14579, Listeria monocytogenes ATCC 15313, Staphylococcus aureus KCTC 1916, Escherichia coli O157:H7 ATCC 43895, and Salmonella enterica serovar Typhimurium ATCC 4931 were selected to determine the antibacterial activity of the bacterial isolates. Among 233 isolates from the three foods, 36 isolates (15.5%) showed antibacterial activity against B. cereus ATCC 14579, the highest incidence of inhibition, followed by S. aureus KCTC 1916 (7.7%) and L. monocytogenes ATCC 15313 (6.0%). However, only five and three strains among the isolates exhibited inhibitory activity against Gram-negative indicators, E. coli ATCC 43895 and Sal. enterica ATCC 4931, respectively. The proteolytic activity of the isolates was determined via hydrolysis of skim milk after 24, 48, and 72 h incubation. After 72 h incubation, 72 out of 233 isolates (30.9%) showed proteolytic activity, and the isolates of fermented jinuari exhibited the highest incidence of proteolytic activity (60%, 36 isolates). These results suggest that ethnic fermented seafoods in the east coast of South Korea might be a promising source of bacterial strains producing antibacterial and proteolytic compounds.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.11a
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• pp.72-73
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• 2005

Stress behavior was studied to investigate the internal behaviors of boron, carbon, and nitrogen in the 1000${\AA}$-thick tungsten boron carbon nitride (W-B-C-N) thin films. The impurities in the W-B-C-N thin films provide stuffing effects that were very effective for preventing the interdiffusion between interconnection metal and silicon substrate during the subsequent high temperature annealing process. The resistivity of W-B-C-N thin film decreases as an annealing temperature increase. The W-B-C-N thin films have compressive stress, and the stress value decreased up to $4.11\times10^{10}dyne/cm^2$ as an $N_2$ flow rate increases up to 3 sccm.

• Journal of Korean Ophthalmic Optics Society
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• v.8 no.1
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• pp.29-33
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• 2003

There are reports that the myopia progression have been difference according to myopia degree and age. In this studies, we divided into three investigated groups. The A group is the lower elementary school(50), the B group is the high elementary school(50), the C group is the junior high school(50) and the D group is the high school students(50). The myopia progression have been compared with each group and most variable terms have been investigated. We have analyzed the refraction inspection record that were investigated to put on spectacles in three years(visiting three times or more). The subject of study were 200 persons(men 100, women 100), 1. The distribution of equivalence with ages : A group -2.72D, B group -2.90D, C group -3.53D, D group -3.96D. 2. The pupillary distance have been 57.4mm(A), 59.9mm(B), 61.6mm(C), 63.4mm(D). 3. On a monthly variation : -0.02D(A), -0.045(B), -0.050D(C), -0.025(D) in men, and -0.06D(A), -0.06D(B), -0.045(C), -0.04D(D) in women. 4. After due considering monthly variation and suppose that the variatting times of spectacles degress were time of refracting inspection. The result : 3.6 month for A group, 4.8 month for B group, 5.3 month for C group and 7.7 month for D group.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.18 no.1 s.116
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• pp.37-43
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• 2007

In this.paper, we introduce design and implementation results of the single balanced diode mixer for European point-to-point microwave radio in order to improve flatness performance. When a resonator such as RF filter is integrated with a mixer, impedance characteristic of 50 ohm is maintained only in RF band, not in LO band resulting deterioration of flatness performance because of LO power variation on the diode. In the paper, we suggest a design method of mixer integrated with image rejection filter and LO harmonic filter to have a better performance of flatness using embedding electrical length between filter and mixer's port. Frequency specification of fabricated mixer is $21.2{\sim}22.6\;GHz$ for RF, $19.32{\sim}20.72\;GHz$ for LO and 1.88 GHz+/-50 MHz for IF, respectively. Measured results show conversion loss of 8.5 dB, flatness of 2 dB, input PldB of 8 dBm, IIP3 of 15 dBm under LO power level of 10 dBm. Return losses of RF, LO and IF port are under -12 dB, -10 dB and -5 dB, respectively. Isolations of LO/RF and LO/IF are 20 dB and 50 dB, respectively.

• Proceedings of the Optical Society of Korea Conference
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• 1989.02a
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• pp.123-126
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• 1989

두 개의 모드가 간섭하는 LiNbO3 광도파로를 이용하여 기존의 편광 분리기와는 달리 두 개의 전극에 의해 두 편광의 출력을 임의로 조절할 수 있는 편광 분리기를 제작하였으며, 두 전극에 각각 52V, 72V를 걸어주어 20dB 이상의 분리도를 얻을 수 있다.

• Journal of Aquaculture
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• v.19 no.4
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• pp.254-260
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• 2006

A 6-week feeding trial was conducted to determine apparent protein and phosphorus digestibilities in order to evaluate nine different dietary protein sources in growing olive flounder, Paralichthys olivaceus. Nine diets containing fish meal analog ($BAIFA-M^{TM}$), white fish meal (WFM), flounder muscle powder (FMP), squid liver powder (SLP), leather meal (LM), soybean meal (SM), corn gluten meal (CGM), poultry by-product (PBP) or egg albumin(EA) were prepared by mixing a basal diet (BD) with one of nine test ingredients at the ratio of 7 to 3. Apparent protein digestibilities of FMP, SLP, WFM, SM, CGM, LM, PBP, $BAIFA-M^{TM}$, and EA were 94%, 92%, 86%, 82%, 75%, 72%, 72%, 71%, and 30%, respectively. Apparent phosphorus digestibilities of FMP, SLP, $BAIFA-M^{TM}$, LM, WFM, PBP, CGM, EA and SM were 77%, 72%, 65%, 55%, 54%, 50%, 20%, 20%, and 17%, respectively. Weight gain of fish fed FMP ($323^a$) was significantly higher than those of fish fed the other diets, and those of fish fed basal diet ($302^b$), SLP ($305^b$) and WFM ($308^b$) diet were significantly higher than those of fish fed SM ($274^c$), $BAIFA-M^{TM}\;(268^{cd}),\;PBP\;(261^{de}),\;LM\;(251^e),\;CGM\;(254^e)$ and EA ($181^f$). Based on the results of apparent protein digestibilities, apparent phosphorus digestibilities and weight gain, SLP, SM and $BAIFA-M^{TM}$ could be one of good protein source to replace fish meal in flounder diets.

• 한국정보통신설비학회:학술대회논문집
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• 2007.08a
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• pp.3-6
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• 2007

In this paper, a hybrid dual band LNA(Low Noise Amplifier) with a tunable matching circuit using varactor is designed for 433MHz and 912MHz RFID reader. The operating frequency is controlled by the bias voltage applied to the varactor. The measured results demonstrate that S21 parameter is 16.01dB and 10.72dB at 433MHz and 912MHz, respectively with a power consumption of 19.36mW. The S11 are -11.88dB and -3.31dB, the S22 are -11.18dB and -15.02dB at the same frequencies. The measured NF (Noise Figure) is 15.96dB and 7.21dB at 433MHz and 912MHz, respectively. The NF had poorer performance than the simulation results. The reason for this discrepancy was thought that the input matching is not performed exactly and a varactor in the input matching circuit degrades the NF characteristics.

• Journal of IKEEE
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• v.13 no.3
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• pp.72-79
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• 2009

This paper describes a compact microstrip active antenna with dual polarization. The antenna, receiving both a left-hand circularly polarized wave and a right-hand circularly polarized wave, has a function of polarization diversity. A square-shaped empty room is located on the inside of the microstrip radiator so that the size has been reduced. And slots are added around feeding point to improve input matching. Also, amplifier and switching circuitry are placed at the empty room to increase antenna gain and to select one of the circular polarizations, respectively. The proposed antenna has been applied to GPS(global positioning system). The measurement results show that it has 10dB-impedance bandwidth, 3dB axial bandwidth of about 50MHz, 3dB beamwidth of 90degree, and gain of 13dBi, respectively, for RHCP. Also, it has 3dB axial bandwidth of about 50MHz, 3dB beamwidth of 84 degree, and gain of 12dBi, respectively, for LHCP.

• Applied Microscopy
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• v.29 no.3
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• pp.363-376
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• 1999

This study aims to demonstrate the effect of chitosan oligosaccharide on the ultrastructural changes in the mouse liver toxicated by carbon tetrachloride $(CCl_4)$. A healthy male ICR mouse that weighted $27{\pm}2gm$ was used for experiment. The experimental group was divided into three groups; the group A; the pretreated group with chitosan oligosaccharide, the group B; the simultaneous group, the group C; treated only the $CCl_4$. The group A was simultaneously treated with chitosan oligosaccharide and $CCl_4$ after pretreated with chitosan oligosaccharide for 7 days. The group B injected $CCl_4$ and chitosan oligosaccharide to the intraperitoneal. The group C injected with only $CCl_4$ to the intraperitoneal. The results were as follow: In the group A, the nuclear membrane and the mitochondria were observed almost normal in shapes at overall the time. Some lamellae of the RER (rough endoplasmic reticulum) destructed until 48 hours but ribosome attached. The destructed lamellae reformed at 72 hours but the smooth membrane vesicles not observed. The lysosomes observed at 72 hours. At 96 hours, all organelles showed in normal shapes. In the group B, changes of nuclear membranes were relatively lighter than group C. Mitochondria observed normal shape through the time. Parts of RER reformed the lamellae, other parts dilated inner cavity. And lipid droplet observed around the 24 hours. Glycogen and lysosome observed 48 hours and 72 hours, respectively. In the group C, nuclear membrane was irregular and nuclear cytoplasm condensed through the time. The lamellae of RER destructed from 24 to 96 hours. Smooth membrane vesicles observed in the cytoplasm at 48 ours. Mitochondria was less effected by toxic. And from the 24 hours, the variable sizes of lipid droplets observed in tile cytoplasm. These results suggest that chitosan oligosaccharide attenuates the toxic effect of the carbon tetrachloride in the mouse liver.