• Clinical and Experimental Reproductive Medicine
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• 제2권2호
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• pp.41-46
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• 1975

Careful scruting of the data indicate that malnutrition actually limits fertility. Spermatogenesis may likewise be impaired by inadequate diet, particularly one that is very poor in protein. For those who are underweight, increased caloric intake stressing high protein content is recommended. Included are supplementary vitamins, particularly B complex, which stimulate the appetite. Injudicious dieting by the woman to conform to current standards of beauty may also result in malnutrition. This contributes to faulty oogenesis and, in extreme dieting, may produce a long-standing amenorrhea. Obsity may also reduce fertility. Since most cases of obesity are due to over-eating, the full cooperation of the patient must be enlisted. And no device is effective for breaking up fatty deposits. Instead, a program of exercise is recommended. The treatment of both malnutrition and obesity is directed toward general dietary habits either weight gain or weight reduction, with a well balanced high protein diet.

• Asian-Australasian Journal of Animal Sciences
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• 제18권1호
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• pp.61-65
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• 2005

The objective of this work was to investigate the nutritional requirements for the growth of Actinomyces sp. 9RCC5 isolated from the rumen of a native goat in Korea. The growth of strain 9RCC5 on the basal medium or the medium minus certain ingredients from the basal medium demonstrated that strain 9RCC5 showed absolute requirement of vitamin B complex mixture, while hemin and volatile fatty acids (VFA) were stimulatory to growth to some extent. The 9RCC5 strain grew well with casein hydrolysate as the sole added nitrogen source. However, neither a complex of 18 amino acids nor ammonium sulfate effectively replaced casein hydrolysate. Vitamins such as riboflavin and pantothenate were essential for growth, while thiamin and biotin were stimulatory. With regard to VFA, the growth was stimulated by acetic acid but inhibited by valeric acid. Relatively large quantities of $Na^+$, $K^+$ and $Ca^{2+}$ were absolutely required for growth. Supplementation of clarified rumen fluid to the basal medium in a range of 0-10% (vol/vol) resulted in an increased rate of growth as well as an increased extent of growth.

• 환경위생공학
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• 제6권2호
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• pp.17-31
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• 1991

The effects of environmental agents on health are great concern for all. It was recognized that each human has differential susceptibility to environmental effects. Susceptibility are changed by many factors includin gdevelopmpntal processes, genetic factors, nutritional stratus, preexisting disease conditions, life style and personal habits. Of all factors nutritional factors seem to be the area most modifiable. Consequently, It is an area that must be more thoroughly evaluated. In this paper, nutrient and environment interactions are reviewed briefly with published literatures. This paper deals with the influence of micronutrients(energy, protein and fat), Vitamins (vitamin 4, vitamin B-complex, vitamin C, vitamin D and vitamin I) and Minerals(calcium, iron, selenium, zinc and other minerls) on environmental effects. The role of arch nutrient was assessed in modifyine the expression of environmental pollutant toxicity with available litertures. In each nutrient section, the effect of environment was considered in following agents : heavy metals(lead, cadmium, mercury, silver and etc), inorganic agents(nitwits, sulfite, fluoride and etc), organic agents(benzene, carbon tatra-chloride, aflatoxin, auto dye, dialbrin etc), Irritant gas(ozone, carbon monooxide and etc), physical agents(X-irradiation, ultra violet, temperature and noise) and insectcides. The extent to which nutritional status modifies environmental effects 3nd its converse, how envirollments affects nutritional status is very complex. In deed, at the present time there are more than 50 chelnical/phycical agents that affect the nutrient metabolism and/or have their toxicity either directly diminished or enhanced by nutrients of those agents, small number of agents for each nutrients have sufficient evidence to warrant any reasonable degree of confidence in their hypothesized associtation. With these information at this present time it is hard to conclude that the recommended dietary allowance for each nutrient should be reconsidered.

• 한국식품위생안전성학회지
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• 제22권1호
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• pp.1-14
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• 2007

The term, "food safety", has traditionally been viewed as a practical science aimed at assuring the prevention acute illnesses caused by biological microorganisms, and only to a minor extent, chronic diseases cause by chronic low level exposures to natural and synthetic chemicals or pollutants. "food safety" meant to prevent microbiological agents/toxins in/on foods, due to contamination any where from "farm to Fork", from causing acute health effects, especially to the young, immune-compromised, genetically-predisposed and elderly. However, today a broader view must also include the fact that diet, perse (nutrients, vitamins/minerals, calories), as well as low level toxins and pollutant or supplemented synthetic chemicals, can alter gene expressions of stem/progenitor/terminally-differentiated cells, leading to chronic inflammation and other mal-functions that could lead to diseases such as cancer, diabetes, atherogenesis and possibly reproductive and neurological disorders. Understanding of the mechanisms by which natural or synthetic chemical toxins/toxicants, in/on food, interact with the pathogenesis of acute and chronic diseases, should lead to a "systems" approach to "food safety". Clearly, the interactions of diet/food with the genetic background, gender, and developmental state of the individual, together with (a) interactions of other endogenous/exogenous chemicals/drugs; (b) the specific biology of the cells being affected; (c) the mechanisms by which the presence or absence of toxins/toxicants and nutrients work to cause toxicities; and (d) how those mechanisms affect the pathogenesis of acute and/or chronic diseases, must be integrated into a "system" approach. Mechanisms of how toxins/toxicants cause cellular toxicities, such as mutagenesis; cytotoxicity and altered gene expression, must take into account (a) irreversible or reversal changes caused by these toxins or toxicants; (b)concepts of thresholds or no-thresholds of action; and (c) concepts of differential effects on stem cells, progenitor cells and terminally differentiated cells in different organs. This brief Commentary tries to illustrate this complex interaction between what is on/in foods with one disease, namely cancer. Since the understanding of cancer, while still incomplete, can shed light on the multiple ways that toxins/toxicants, as well as dietary modulation of nutrients/vitamins/metals/ calories, can either enhance or reduce the risk to cancer. In particular, diets that alter the embryo-fetal micro-environment might dramatically alter disease formation later in life. In effect "food safety" can not be assessed without understanding how food could be 'toxic', or how that mechanism of toxicity interacts with the pathogenesis of any disease.

• Journal of Nutrition and Health
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• 제25권6호
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• pp.450-460
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• 1992

본연구는 사람을 대상으로하여 8주간 종류가 서로 다른 옥수수겨를 식이섬유질의 급원으로 기본식이에 첨가하여 먹였을 때 티아민, 나이아신 및 판로텐산의 체네 이용율을 살펴보고자 실시되었다. 실험식이의 종류의 옥수수겨를 첨가하지 않은 기본식이(Basal diet : B)와 이에 wet-milled fine(WF)/coarse(WC) corn bran이나 dry-milled fine(DF)/coarse(DC) corn bran을 첨가한 식이들로서 무작위법에 의하여 첫 4주간동안 일부의 피실험자는 B, WF, WC 식이를 급여 받았으며, 나머지 피실험자는 B, DF, DC를 급여받았다. 따라서, 각각의 피실험자들은 8주간의 실험기간동안 모든 실험식이를 섭취하였다. 비타민의 이용율을 측정하기 위하여 24시간 뇨를 채집하였으며 이들을 주별로 나누어 이들 비타민의 뇨중함량을 측정하였고 변을 채집, 건조하여 neutral detergent fiber(NDF)량을 측정하였다. 또한 매일 뇨증의 creatinine치를 측정하여 뇨의 완전한 채집을 도모하였으며 불완전한 채집으로 인한 실험오차를 줄여주기 위하여 비타민의 이용을 계산시 각 주별의 평균 creatinine치에 대하여 비타민 이용율을 보정하여 주었다. 실험분석 결과에 따르면 옥수수겨를 첨가한 식이를 먹는 경우 티아민, 나이아신 및 판토텐산의 생체 이용율이 저하되는 것으로 나타났으며 옥수수겨를 wet-milling 방법으로 처리한 식이의 경우 저하의 효과가 더운 현저한 것으로 보여졌다. 또한 옥수수겨의 처리방법을 막론하고 옥수수겨의 입자가 거친것이 비타민 이용율의 저하효과가 더욱 큰것으로 나타났다. 변건량과 변량에 있어서도 이와 유사한 양상을 보였고 특히 fecal trasit time이 wet-milled corn bran 식이군과 입자가 거친 옥수수군에서 빨랐다. 따라서 본 연구는 옥수수겨가 이들 세가지 B 비타민의 이용율을 저하시키는 것이 식이 섬유질의 종류에 따라서 영향을 받을 수 있음을 시사하고 있다.

• 한국치위생학회지
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• 제19권3호
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• pp.387-397
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• 2019

Objectives: This study was conducted to examine the subjects' oral health status and changes in the oral environment after mouthwash with effervescent Vitamin C and its intake and to understand the impact on changes in the number of bacteria causing periodontal diseases in the oral cavity based on the oral health status and oral environmental condition. Methods: After obtaining approval from the Institutional Review Board of D-University, 45 people (24 in an experimental group and 21 in a control group) who participated in the oral health program were selected, among visitors of the Clinical Dental Hygienics Laboratory of D. University in B. Results: Based on the subjects' periodontal health status, the number of bacteria causing periodontal diseases in the oral cavity decreased in both experimental and control groups before and after the experiment. However, in the experimental group, it was significant when the Bleeding on Probing(BOP) level was below average, and Calculus index(CAL) was above average, in Aggregatibacter actinomycetemcomitans and the red complex. It was also significant when CAL was above average in the orange complex in the control group. Regarding bacterial changes in periodontal diseases based on the subjects' oral environmental condition, there was a significant change in the Adenosine Tri Phosphate (ATP : intraoral contaminants test) test in the oral cavity in A. actinomycetemcomitans and the red complex in the experimental group and in the O'Leary index in the control group. Further, there was a significant change in the orange complex in the ATP test in the experimental group. Conclusions: A comprehensive analysis of the results revealed that the oral health care program for dental hygiene decreased the number of bacteria causing periodontal diseases in the oral cavity in both experimental and control groups.

• 한국식품영양과학회지
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• 제45권7호
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• pp.980-989
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• 2016

본 연구에서는 아마란스 잎의 식품학적 가치를 향상시키고, 기능성 쌈 채소로의 육성과 활용에 기초자료를 제공하고자 국내에서 재배된 아마란스 Amaranthus cruentus와 Amaranthus hypochondriacus 어린잎의 영양성분을 비교 조사하였다. 아마란스 두 종류의 일반성분은 수분이 대부분을 차지하였으며, A. hypochondriacus보다 A. cruentus의 수분 함량이 더 높았다. 반면 A. hypochondriacus 잎의 조회분, 조단백, 조지방, 탄수화물 및 식이섬유 함량이 A. cruentus 잎보다 높았다. 아마란스 잎의 주요 유리당은 fructose와 glucose로 확인되었으며, fructose는 A. hypochondriacus의 잎에서, glucose는 A. cruentus의 잎에서 더 높게 측정되었다. 유기산은 succinic acid를 제외한 acetic, malic, fumaric acid가 검출되었으며, 아미노산은 methionine과 proline, tyrosine을 제외한 총 17가지가 함유되어 있는 것으로 확인되었다. 두 아마란스 잎 모두 필수 아미노산 함량보다 비필수 아미노산 함량이 더 높았으나 비필수 아미노산 중 glutamic acid의 함량이 가장 높게 함유되어 있어 이에 따른 감칠맛의 정미성이 있을 것으로 생각된다. 또한, 기타 아미노산으로 다양한 생리활성을 가진 taurine과 GABA(${\gamma}$-amino butyric acid)가 다량 함유되어 있어 기능성 쌈 채소로의 역할이 기대된다. 아마란스 두 종류의 무기질은 K이 대부분을 차지하였으며, 모든 무기질은 A. cruentus보다 A. hypochondriacus에서 높았다. 아마란스 잎의 지방산은 대부분 불포화 지방산이었으며, 그중에서도 오메가-3 지방산인 linolenic acid 함량이 높은 비중을 차지하고 있었다. A. cruentus와 A. hypochondriacus 잎의 ${\beta}$-carotene 함량은 각각 $478.72{\mu}g/100g$, $474.12{\mu}g/100g$으로 측정되었으며, 비타민 B군은 $B_2$, $B_3$, $B_5$만이 검출되었고 $B_1$, $B_6$, $B_{12}$는 검출되지 않았다. 또한 A. hypochondriacus 잎에는 A. cruentus 잎보다 더 많은 양의 항산화 비타민 C와 E를 함유하고 있었다. 이상의 결과로 아마란스 잎은 품종, 재배 지역 및 환경 등에 따라 각 함량에 차이는 있으나 다양한 영양성분을 함유하고 있는 것으로 조사되었으며, 이에 따라 기능성 쌈 채소로써의 이용성이 높을 것으로 기대된다.

• 치위생과학회지
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• 제14권4호
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• pp.468-476
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• 2014

본 연구는 국민건강영양조사 제4기 자료를 이용하여 한국 성인에서 비타민 섭취와 치주염과의 관련성을 구명하고자 하였다. 국민건강영양조사 원시자료에서 건강조사와 구강검진 및 식이조사에 모두 참여한 19세 이상 성인 6,245명의 자료를 추출한 후 복합표본설계를 반영하기 위하여 가중치를 고려한 통계분석을 실시하였다. 대상자의 인구사회학적 특성, 전신건강상태와 행태, 구강건강상태와 행태 및 비타민 섭취 5분위에 따른 치주염 유병률의 차이를 ${\chi}^2$-검정을 이용하여 분석하였으며, 로지스틱 회귀분석을 이용하여 인구사회학적 특성, 전신건강상태와 행태 및 구강건강상태와 행태를 보정한 비타민 섭취와 치주염과의 관련성을 분석하였다. 치주염 유병률은 성별, 나이, 결혼상태, 교육, 수입에 따라 통계적으로 유의한 차이가 있었으며(p<0.05), 주관적 건강상태, 심혈관질환 여부, 당뇨 여부, 음주행태, 흡연상태, 및 BMI에 따른 차이도 통계적으로 유의하였고(p<0.05), 칫솔질 횟수, 주관적 구강건강상태, 구강위생용품 사용여부에 따른 차이도 통계적으로 유의하였다(p<0.05). 한편 고려된 비타민 중 비타민 A와 레티놀 및 비타민 B2 섭취가 적을수록 치주염 유병위험이 통계적으로 유의하게 높았고, 인구사회학적 특성과 전신건강상태와 행태 및 구강건강상태와 행태를 보정한 후에는 비타민 B2에서만 통계적으로 유의한 관련성이 있었다(OR: Q1=1.00, Q2=0.72, Q3=0.73, Q4=0.76, Q5=0.84). 따라서 적절한 비타민 B2의 섭취는 치주염 유병위험을 감소시킴으로써 한국 성인 인구의 지속적인 치주건강을 유지하는 데 도움이 될 수 있을 것으로 생각된다.

• Nutritional Sciences
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• 제7권4호
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• pp.223-234
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• 2004

The aim of this study was to investigate intake of health foods and supplements and its associated factors in middle and old-aged adults in order to contribute to health promotion of Korean population by providing a guide for proper use of health foods and supplements. About 69% of the subjects reported that they were currently taking health foods and supplements or had experiences of having them in the past, whereas 31.2 % reported they had never taken them. The most commonly used type of health foods and supplements was vitamin C as reported by 41.8% followed by others such as lactobacillus products, multi-vitamins, tonic medicine and cardiotonic drug, artificially processed Ginseng foods, vitamin B complex, enzyme supplement, calcium, aloe, apricot extract products, chitosan products, loyal honey, squalene, refined fish oil and iron products. The major reason for taking health foods and supplements was 'to protect the weak constitution' with 155 (42.1%) responses, and the motive for the intake was the suggestion from family-relatives with 235 (63.9%) responses, and the place of purchase was pharmacy with 140 (38.0%) responses, the average monthly expense was 20,000-40,000 won with 140 (26.2%) responses, and effects after the intake was 'so and so' with 180 (33.6%) responses as the highest. More health foods and supplements were consumed as age and education were statistically significantly increased (p<0.05). For health and lifestyle and the intake of health foods and supplements, perceived health status, the presence of illness, and the presence of health management were statistically significant (p<0.05). Male subjects than female subjects and the 30s than the 405 and 50s were appeared to have poorer dietary behaviors (p<0.05). For the health locus of control and the intake of health foods and supplements, the health locus of control score was 22.82 for consumers and 22.79 for non-consumers, showing no significant difference. Logistic regression analysis was performed to find out major factors that affect the intake of health foods and supplements, in which gender, education, smoking, perceived health status, the presence of illness, and health management were significant to the intake of health foods and supplements. It is shown that subjects with perception and attitude of 'health foods and supplements are useful in health maintenance and disease prevention' and 'the information and variety for health foods and supplements are great' have higher probability of taking health foods and supplements.