• 제목/요약/키워드: B-GT

검색결과 131건 처리시간 0.03초

국내 자생 동백나무(Camellia japonica L.) 추출물의 항산화 및 항미생물 활성 (Antioxidant and Antimicrobial Activities of The Extracts from Native Camellia japonica in Korea)

  • 이숙영;김선민;황은주;표병식
    • 한국자원식물학회지
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    • 제17권3호
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    • pp.314-322
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    • 2004
  • 동백나무의 잎과 꽃의 식용자원화를 위한 일환으로서 동백의 부위별 성분분석, DPPH radical 소거능에 의한 항산화활성, 및 항미생물 활성을 조사하였다. 수분 함량은 꽃과 어린 잎 부위에서 70% 이상의 함유율을 보였고, 조단백질의 함량은 꽃을 제외한 나머지 부위에서 3%이상이었으며, 지방 함량은 씨부위에서 23.08%로 많이 함유되어 있었다. 회분의 함량은 수피 부위에서 2.97%와 탄수화물의 함량은 에서 높게 나타났다. 항산화활성은 어린잎(RC$_{50}$=30.37$\mu\textrm{g}$/mL), 꽃봉오리 (RC$_{50}$=52.97$\mu\textrm{g}$/mL)와 꽃(RC$_{50}$=59.48 $\mu\textrm{g}$/mL)이 높은 활성을 보였으며 합성 항산화제인 BHT의 RC$_{50}$ 값이 584.04$\mu\textrm{g}$/mL의 활성 보다 높은 항산화 활성을 가지고 있음을 확인하였다. 동백을 각 부위별로 추출하여 병원성균과 식중독균, 식품과 관련이 있는 세균 및 효모 등 4균주에 대하여 항미생물 활성을 검토한 결과, 동백의 수피 부위가 P. vulgaris와 B. subtilis에 대한 높은 항균성을 나타내었으며, 특히, 어린잎은 C. albicans와 T. beigelii 모두에 대하여 매우 강한 활성을 나타내었다.을 나타내었다.

녹차 분말 함유 쌀스펀지 케이크의 품질특성 및 산화방지 활성 (Quality characteristics and antioxidant activity of rice sponge cake with added green tea powder)

  • 이민정;황은선
    • 한국식품과학회지
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    • 제48권4호
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    • pp.354-360
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    • 2016
  • 본 연구에서는 녹차 분말을 쌀가루 중량의 1, 3, 5%로 첨가하여 쌀스펀지 케이크를 제조하고 품질특성, 산화방지 활성과 관능적인 특성을 조사하였다. 수분함량은 녹차 분말을 첨가하지 않는 대조군에서 22.59%로 가장 낮았고, 녹차 분말 함량이 증가할수록 수분함량의 범위는 23.82-25.48까지 증가하였다. 케이크의 외관에서는 대조군과 녹차 분말을 1-3% 첨가한 실험군에 비해 녹차 분말을 5% 첨가하여 제조한 스펀지케이크의 부피가 현저히 감소함을 확인하였다. 텍스처 측정 결과, 녹차 분말 함량이 증가함에 따라 경도와 탄력성도 증가하였고, 부착성은 감소하였으며, 응집성, 씹힘성과 탄성은 대조군과 실험군 간에 유의적인 차이가 없었다. 녹차 분말 첨가의 쌀스펀지 케이크 외부 표면 색도 측정결과 $L^*$, $a^*$$b^*$값은 대조군이 가장 높았고, 녹차 분말 첨가량이 증가함에 따라 감소하는 경향을 보였다. 내부색의 경우는 녹차 분말 첨가량이 증가함에 따라 $L^*$값은 감소하였고, $a^*$$b^*$값은 유의적 증가하였다. 총 폴리페놀과 총 플라보노이드, 산화방지 활성 DPPH와 ABTS 라디칼 소거활성 및 환원력을 통해 살펴본 항산화활성은 녹차 분말 첨가량이 증가함에 따라 높게 나타남을 확인하였다. 관능평가인 색, 맛, 향기, 텍스처와 전반적인 만족도에 대한 9점 만족도를 기준으로 관능검사 결과 색에 대한 기호도 측정결과, 쌀가루 중량의 1% 수준에서 첨가할 경우, 향에 대한 선호도는 대조군보다 높았고, 3% 수준에서 첨가할 경우는 질감 및 전체적인 선호도는 대조군보다 높은 점수를 나타냈다.

Substituents Effect on Aziridine Chemistry: N-Inversion Energy, Reactivity and Regioselectivity of Nucleophilic Ring-opening

  • Park, Gyoo-Soon;Kim, Seok-Chan;Kang, Han-Young
    • Bulletin of the Korean Chemical Society
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    • 제26권9호
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    • pp.1339-1343
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    • 2005
  • The N-inversion energies and nucleophilic ring-opening reactions of N-substituted aziridine compounds are investigated using B3LYP/6-31+$G^*$ methods, where substituents (R) on the nitrogen atom has been H (1), Me (2), Ph (3), Bn (4), CHMePh (5), $CO_2Me$ (6), COPh (7) and $SO_2Ph$ (8). The N-inversion energy with X group are decreased as the following order: R = CHMePh (17.06 kcal/mol) $\gt$ Me (16.97) $\gt$ Bn (16.70) $\gt$ H (16.64) $\gt$ $SO_2Ph$ (12.18) $\gt$ Ph (8.91) $\gt$ COPh (5.75) $\gt$ $CO_2Me$ (5.48). For reactivity of the ring opening toward cyanide ion, the aziridine 6 (R=$CO_2Me$) is shown to be the most reactive one. During the ring opening of aziridine 6 by CN$^{\ominus}$, the torsional OCNC angle becomes near to $180^{\circ}$, where the geometry allows for the effective incorporation of electrons of the nitrogen atom to the C=O bond. It would be a possible driving force for nucleophilic ring opening reaction as well as decreasing the N-inversion energy barrier. Regarding to the regioselectivity, the orientation of nucleophile in ring opening reaction appears to be different in the case of 9 and 10. The results are discussed in terms of steric/electronic effect of the $C_2$-substituents.

The Anti-hepatotoxic Effect of Ginseng in Rats: Meta-analysis

  • Kook, Se-Jeong;Han, Hye-Kyoung;Kim, Gun-Hee;Choi, Ki-Heon
    • Journal of the Korean Data and Information Science Society
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    • 제19권3호
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    • pp.937-949
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    • 2008
  • The purpose of this meta-analysis was to investigate the anti-hepatotoxic effect of ginseng in rats induced with CC14 or TCDD, the toxicities that cause liver damages. Primary studies were collected from the ScienceDirect database, the DBpia, and the KISS. The data on the effect factors in plasma and in enzyme are listed as many as possible: The effect factors were alanine transaminase(ALT), aspartate transaminase(AST), liver aminopyrine N-demethylase(AD), liver aniline hydroxylase(AH), liver 3,4-Methylenedioxyamphetamine(liver MDA), cytochrome P450(P450), serum alkaline phosphatase(ALP), serum lactate dehydrogenase(LDH), cytochrome b5(Cyto b5), glutathione reductase (GR), Liver glutathione S-transferase(GST), liver glutamyltransferase (GT), Liver($\gamma$-GCS), serum liver 3,4-Methylenedioxyamphetamine(serum MDA), serum sorbitol dehydrogenase(SDH), serum total protein(TP), and serum $\gamma$-glutamyltransferase($\gamma$-GT). In order to investigate the effect of ginseng, the standard mean difference(HG) between the group of rats induced with toxicity(RH) and the group of rats induced with ginseng(RHG) were combined, and the significance of HGs were tested. The combined HGs checked the biases caused by heterogeneity among studies and the publication biases. Then they were adjusted by using the random effect model and trim and fill method. Although the publication biases were assumed, among all plasma factors the HGs of ALT, AST, serum MDA, SDH, TP, and $\gamma$-GT were significant, and among all enzyme factors the HGs of liver MDA, Cyto b5, GR, GST, and GT were significant. The treatment with ginseng significantly affected the plasma and enzyme levels in rats induced with toxicity.

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The Anti-hepatotoxic Effect of Ginseng in Rats: Meta-analysis

  • Kook, Se-Jeong;Han, Hye-Kyoung;Kim, Gun-Hee;Choi, Ki-Heon
    • Journal of Ginseng Research
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    • 제32권2호
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    • pp.161-170
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    • 2008
  • The aim of this meta-analysis was to systematically investigate the anti-hepatotoxic effect of ginseng in rats induced toxicity which damage to liver. Primary researches were gained on the ScienceDirect database, the DBpia, and the KISS, and the data about the effect factors in plasma and in enzyme were listed as many as possible. The effect factors were alanine transaminase (ALT), aspartate transaminase (AST), liver aminopyrine N-demethylase (AD), liver aniline hydroxylase (AH), liver 3,4-Methylenedioxyamphetamine (liver MDA), cytochrome P450 (P450), serum alkaline phosphatase (ALP), serum lactate dehydrogenase (LDH), cytochrome b5 (Cyto b5), glutathione reductase (GR), Liver glutathione S-transferase (GST), liver glutamyltransferase (GT), Liver (${\gamma}-GCS$), serum liver 3,4-Methylenedioxyamphetamine (serum MDA), serum sorbitol dehydrogenase (SDH), serum total protein (TP), serum ${\gamma}-glutamyltransferase$ (${\gamma}-GT$). To investigate the effect of ginseng, the mean difference (MD) between the group of rats induced by toxicity (RH) and the group of rats induced by toxicity with ginseng (RHG) were combined, and the significance of MDs were tested. The combined MDs were checked the biases caused by heterogeneity among studies and the publication biases, and adjusted by using random effect model and trim and fill method, respectively. The effect about ALT, AST, ALP, LDH, SDH, TP and ${\gamma}-GT$ in plasma factors were significant, and about AD, liver MDA, P450, Cyto b5, GR, GST, GT and ${\gamma}-GCS$ in enzyme factors were significant. The treatment with ginseng supplementation was significantly effected on plasma and enzyme factors of damaged-rats.

기관소음의 수중전파에 관한 연구 (The Underwater Propagation of the Noise of Ship's Engine)

  • 박중희
    • 수산해양기술연구
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    • 제16권2호
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    • pp.69-76
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    • 1980
  • This paper describes the measurement of the underwater noises produced by the engine vibration around the engine room of stern trawler MIS Sae-Ba-Da(2275GT, 3,600 PS) and pole kner M/S Kwan-Ak-San (243 GT, 1000 PS) while the ship is stopping. The underwater noise pressure level was measured with the underwater level meter of which measuring range is 100 to 200 dB(re bLPa). A and B denotes the maximum pressure level measured at right beneath the bottom of the engine room, while the main engine of the Sae-Ba-Da revoluted at 750 and 500 rpm, respectively. C denotes that of the main engine of the Kwan-Ak-San revoluted at 350 rpm, and D that of the generator of the Sae-Ba-Da revoluted at 720 rpm. Thus A, B, C and D were set for the standard sound source for the experiment. The results obtained are as follows: 1. The noise Pressure level at A, B, C and D were 170.5,165,153 and 158dB, respectively. 2. When the check points distanted vertically 1, 10, 20, 30, 40, 50m from the sound source, the underwater noise presure levels were 170.5, 155, 148, 144 and 138 dB and the directional angle was 116\ulcorner in case of A. 3. The sound level attenuated at the rate of 20dB per 10" meters of the horizontal distance from the sound sources. 4. The frequency distribution of the noise was 100Hz to 10KHz and predominant frequency was 700 to 800Hzminant frequency was 700 to 800Hz

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하부 사이클 추가에 의한 MCFC 시스템의 성능향상 (Enhancement of MCFC System Performance by Adding Bottoming Cycles)

  • 지승원;박성구;김동섭
    • 대한기계학회논문집B
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    • 제34권10호
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    • pp.907-916
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    • 2010
  • 고온형 연료전지인 MCFC 발전시스템에 가스터빈, 유기매체 랜킨 사이클, 순산소 연소 사이클 등 다양한 하부 사이클을 추가한 통합시스템들의 성능을 비교 해석하였다. MCFC 시스템의 성능과 운전조건을 바탕으로 하여 각 추가 시스템의 주요 설계 변수 변화에 따른 통합시스템의 성능 변화를 해석하였고 이로부터 각 시스템의 최적 성능을 도출하였다. 각 시스템을 비교하여 MCFC와 최적의 결합을 나타내는 시스템을 분석하였는데, MCFC/OXY 시스템이 MCFC 단독 시스템에 비하여 가장 큰 출력 증가를 나타내었으며, MCFC/GT 시스템의 효율 증가가 가장 큰 것으로 나타났다.

전력용변압기 단선 보호용 NGR 성능 개선 (The Improvement of NGR for Power Transformer Open Circuit Protection)

  • Kang, Y.W.;Shim, E.B.;Kwak, J.S.
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2004년도 추계학술대회 논문집 전기설비전문위원
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    • pp.83-88
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    • 2004
  • As the electric system is getting larger to meet the increasing demand for electric power, the rating of power apparatus is becoming inevitably higher in its working voltage and larger in its capacity. According to KEPCO reports, power transformers in the KEPCO system have undergone troubles such as winding short insulation breakdowns every year since 1981. the cause of this troubles were high one line grounding fault currents in KEPCO systems that had direct grounding systems. KEPCO has installed the NGR(neutral grounding reactor) to lower this fault current and reduced winding short insulation breakdowns in power transformers. But when a circuit breaker opened a no load bus, some trips of circuit breakers for protecting transformer have occurred by mal-operation of 59GT(overvoltage ground relay) that detect disconnection of NGR. Therefore, in this paper, we analyzed the cause and examined the effect of time delav circuit to prevent wrong operation of 59GT.

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두시 하태독법의 IL-4 활성 조절이 D. farinae 유도 아토피유사피부염 발병 조절에 미치는 효과 (The Effect of Douchi Hataedock Treatment for Dermatophagoides Farinae-Induced Atopic Dermatitis-like Skin Lesions by Controlling IL-4 Activity)

  • 안상현;김재규;천진홍;김기봉
    • 대한한방소아과학회지
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    • 제31권1호
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    • pp.43-51
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    • 2017
  • Objectives Hataedock method is a Korean medical therapy which removes fetal toxin by orally administering herbal decoction to neonates. This study was to observe skin damage and anti-inflammatory effect via regulating IL-4 activity in NC/Nga mice which were induced atopic dermatitis (AD)-like skin lesion by Dermatophagoides (D.) farinae after applying Douchi Hataedock method. Methods NC/Nga mice with 3 weeks of gestational age were used. Each 10 mice were allocated to the control group (Ctrl), the AD-induced group (AE), and the group which induced AD after administering Douchi extract (GT). After 4 weeks from administering Douchi extract to the mice, the primary AD was induced by applying D. farinae extract 6 times per week for 3 weeks and then the secondary AD was induced by the same method after 1 week from the primary AD induction. To identify the skin damage and anti-inflammatory effect, we observed LxR, IL-4, Fc ${\varepsilon}$ receptor, substance P, and $NF-{\kappa}B$. Results The GT group showed alleviation of skin injury and decrease in capillary angiogenesis. Stratum corneum damage, epithelial cell hyperplasia, lymphocyte infiltration, and capillary distribution relatively decreased in the GT group. LxR-positive reaction in the GT group were increased by 53% than that of the AE group. IL-4 production, $Fc{\varepsilon}$ receptor activity, and substance P-positive reaction in the GT group were decreased by 82%, 42%, and 82% respectively compare to those of the AE group. $NF-{\kappa}B$-positive reaction in the GT group were decreased by 15% compare to that of the AE group. Conclusions Hataedock method with Douchi extract alleviated AD via reducing inflammatory cytokines secreted at the early stage of AD. Thus, Douchi Hataedock method has a beneficial effect for the prevention and treatment of AD.

식이불포화지방산을 섭취한 Apo E KO Mice에서의 녹차의 항동맥경화억제 효과 (Anti-atherosclerotic Effect of Green Tea in Poluynsaturated Fatty Acids-treated Apo E KO Mice)

  • 김효숙;이명숙
    • Journal of Nutrition and Health
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    • 제44권6호
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    • pp.465-473
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    • 2011
  • Dietary fatty acids are under intense research to identify anti-atherogenic mechanisms, so we investigated green tea powder (GT) as a protector against atherogenesis originating from lipid peroxidation such as 4-hydroxynonemal (4-HNE) and malondialdehyde (MDA) in different dietary fatty acid-treated apo E KO mice. Growth rate and dietary efficiency were lower in apo E KO mice with or without LA compared to wild type. Plasma total cholesterol (TC) and triacylglycerol (TG) did not correspond to values in other tissues, but TG in heart tissue decreased significantly by GT after linoleic acid (LA) or docosahexaenoic acid (DHA) was administered. LA induced apoptosis as evidenced by changes in aorta morphology and immunohistochemistry. Lipid peroxides (LPO) was increased in apo E KO mice with or without LA corresponding to the accumulation of 4-HNE or MDA in the proximal aorta above the atria. GT consumption tended to reduce the primary causal mechanism of atherogenic phenomena such as oxidizability in both LA and DHA treated atherogenic mice. A high polyunsaturated fatty acids (PUFA) diet involved the changes on stress-induced apoptotic signaling by increasing caspase 3, cytochrome c, and nuclear factor-${\kappa}B$ in the heart tissue, but decreasing the bcl-2 protein. However, GT remarkably reduced the expression of apoptotic signaling, in contrast to the PUFA diet. Therefore, the potential of GT as an anti-atherosclerotic dietary antioxidant was tested in this study.