• Bulletin of the Korean Chemical Society
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• v.16 no.9
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• pp.831-834
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• 1995

The nature of hydrogen bonding between thioacetamide and azines has been thoroughly investigated using near IR absorption spectroscopy. The νN-H + amide II combination band in thioacetamide (TA) has been analyzed to determine the thermodynamic constants for the formation of hydrogen bonded 1:1 TA:azine complexes in CCl4 and CHCl3 solutions. The relative stabilities of TA-azine complexes (pyridine->1,2-diazine->1,3-diazine->1,4-diazine-TA) are in good agreement with the relative proton affinities of azines in the gas phase. The results serve as a basis for analyzing the factors which influence the hydrogen bonding formation of TA in nonaqueous solutions.

• Bulletin of the Korean Chemical Society
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• v.34 no.11
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• pp.3459-3462
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• 2013

• Korean Journal of Microbiology
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• v.36 no.3
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• pp.209-215
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• 2000

The purpose of U7is work was to iilvestigate the degradation of s-h~azine hel-hicidcs, ahilzine and simazine by TNT-degrader under several relevaut physicochemical environ~nental parameters. TNT-degrader showed effective degradability of atrazine and snnazine as well. Both atrazme (GO 1i1~11) and simazine ( 4 5 rng//) were completely degraded within 30 hrs and 4 days of incubation, respectively. As d ~ e concentrations of atrazine and sunazine increased in the media, the degradation ofthose compounds were delayed. Additional caubans were essential to degrade atrazine and simazule, and no degradation was achieved in the absence of additional carbons. The effect of supplemented nitrogens on the degradation of atrazine and sunazine was evalualed. Addition of a suppleinented nitrogen in he growth medium containing ah-azine or siinazine showed partial degr-adation olihose herbicides duriug the incubation period. However, complete degradation of atrazine and simazu~e was examined ul the absence or any supplemented nitrogens. Addltion of yeast extract in this study was inhibilory to atrazine aud siinazine degradations, respectively. TNT-degrader was a small Gram-negative cocco-bacillus. Physiological analysis using BIOLOG sysleln revealed that this strain was Ste~~ol~~opl~orno~~ns rrialtophilia.

• Journal of the Korean Chemical Society
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• v.56 no.1
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• pp.78-81
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• 2012

Aromatic 2,3-diazabuta-1,3-dienes in glacial acetic acid with isothiocyanate in the presence of catalyst $TiCl_4$ at room temperature produced via criss-cross cycloaddition reactions the corresponding perhydro[1,2,4]triazolo[1,2-a][1,2,4] triazole-1,5-dithiones in relatively high yields and short reaction time.

• Journal of Korean Society for Atmospheric Environment
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• v.18 no.5
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• pp.383-391
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• 2002

Six types of ozone passive samplers were fabricated with three different filter substrates and two colorants, and tested for their feasibility on atmospheric monitoring. These passive samplers are based on a colorant which fades (indigo carmine and ChromAir (K&M environmental Inc.)) or produces color (mixture of 3-methyl-2-benzothiazolinone acetone azine and 2-phenylphenol colorant) upon reaction with ozone, whose concentration can be determined by reflectance measurement of the color change. Three filters, namely Whatman No.1 paper, SG81 chromatography paper and Silica Gel coated on polyester (TLC Plates), were prepared and coated with two colorants. The response of these passive samplers in ozone chamber were tested and compared with ChromAir (K&M environmental Inc.) passive sampler. The response of Silica Gel filter impregnated with indigo carmine was the best at the constant concentration exposure.

• The Korean Journal of Pharmacology
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• v.4 no.1 s.5
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• pp.9-16
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• 1968

The author studied the hemolytic action of phenothiazine derivatives such as promazine, prochlorper azine, perphenazine and thiethylperazine on rabbit erythrocytes, and obtained the following results: 1. Promazine, prochlorperazine, perphenazine and thiethylperazine caused hemolysis in vitro in the following order: Thiethylperazine>perphenazine>prochlorperazine>promazine. 2. Cholesterol inhibited the hemolytic action of prochlorperazine, perphenazine and thiethylperazine, but had no effect on promazine hemolysis. 3. Dextrose, albumin and blood plasma protected erythrocytes against promazine, prochlorperazine, perphenazine and thiethylperazine. 4. The intravenous injection of promazine, prochlorperazine, perphenazine and thiethylperazine caused hemolysis in the same order as they did in vitro.

• The Korean Journal of Zoology
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• v.34 no.4
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• pp.610-617
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• 1991

계배 근원세포의 분화 및 증식에 미치는 F3+의 영향을 조사하였다. 철이 없는 배양액은 근원 세포의 분화와 증식을 억제하는 것으로 나타났으며 , 따라서 근원세포의 분화에 철과 transferrin (Tf)은 필수적이다. 또한, 철 대신에 Co2+가 부착된 Tf가 첨가된 배양액에서도 근세포의 분화가 정상적으로 일어나는 것으로 나타났다. Lysosomotrophic amine(chloroquine, $\mu$M 수준;ammonium chloride, mM 수준)은 근세포의 분화와 증식을 억제시켰으며 , 근세포 분화의 철에 대한 의존성은 분화됨에 따라 둔화되었다. 세포내로의 T니 수송량은 MEM과 8102배양액에서 비슷하였고, 근세포가 분화됨에 따라 감소하였다. Lysosomotrophic azine은 최소한 3시간이 내에서는 세포내로 수송되는 Tf의 양에 영향을 미치지 못하였다.

• Archives of Pharmacal Research
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• v.18 no.3
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• pp.195-202
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• 1995

The thio, thio acetyl, oxime, and several hydrazone and azine derivatives of the antitumor alkaloid acronycine (1) were prepared. NMR spectroscopy was used to study the configurations around the C=N double bond in these acronycine derivatives. In the hydrazones and azines of acronycine the N-N bond assumes a syn configuration to the $C_6-OCH_3$ group, while the NO bond in the oxime and the N-N bond in noracronycine hydrazone and azines assumes an anti configuration.

• Journal of the Korean Chemical Society
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• v.45 no.5
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• pp.448-453
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• 2001

Pyrazoloazines are extremely useful in agriculture and medicine. The main objective of this article is to synthesize some new pyrazoloazines. Ethyl 3-amino-1H-pyrazole-4-carboxylate undergoes diazotization, couples with activated methylene compounds and cyclizes to form pyrazolo[5,1-c][1,2,4]tri-azine derivatives. The title compound also reacts with $\alpha$-substituted cinnamonitriles to produce pyrazolo[1,5-a]pyrimidine derivatives. Structures of newly synthesized compounds are established via chemical and spectral methods.

• Journal of Ginseng Research
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• v.39 no.2
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• pp.178-182
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• 2015

Background: Fermentation technology is widely used to alter the effective components of ginseng. This study was carried out to analyze the characteristics and antioxidant activity of ginseng seeds fermented by Bacillus, Lactobacillus, and Pediococcus strains. Methods: For ginseng seed fermentation, 1% of each strainwas inoculated on sterilized ginseng seeds and then incubated at $30^{\circ}C$ for 24 h in an incubator. Results: The total sugar content, acidic polysaccharides, and phenolic compounds, including p-coumaric acid, were higher in extracts of fermented ginseng seeds compared to a nonfermented control, and highest in extracts fermented with B. subtilis KFRI 1127. Fermentation led to higher antioxidant activity. The 2,2'-azine-bis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging activity was higher in ginseng seeds fermented by Bacillus subtilis than by Lactobacillus and Pediococcus, but Superoxide dismutase (SOD) enzyme activity was higher in ginseng seeds fermented by Lactobacillus and Pediococcus. Conclusion: Antioxidant activities measured by ABTS and SOD were higher in fermented ginseng seeds compared to nonfermented ginseng seeds. These results may contribute to improving the antioxidant activity and quality of ginseng subjected to fermentation treatments.