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Retrospective Cohort Study on the Administration of Sedative for Delirium in Terminally Ill Cancer Patients and Survival Time (말기암환자의 섬망으로 인한 진정제 투약과 생존기간에 관한 후향적 코호트 연구)

  • Park, Hyoung Sook;Kim, Dae Sook;Bae, Eun Hee;Kim, Jung Rim;Seo, Jung Hwa;Yun, Jung Mi
    • Journal of Hospice and Palliative Care
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    • v.19 no.2
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    • pp.119-126
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    • 2016
  • Purpose: This study analyzed the difference in survival time of patients with delirium according to sedative medication. Methods: From January 2012 through December 2013, a retrospective cohort study was performed using the electronic medical records (EMR) of Pusan National University Hospital. Among 900 patients who died from cancer, we selected 240 who suffered delirium based on the EMR. The Nu-DESC delirium screening test was used to diagnose delirium. Results: The median length of delirium period was five days. Delirium characteristics were dominated by inappropriate behaviors (35.0%). Sedatives were administered in 72.1% of the cases. The most frequently used sedative was haloperidol which was used in 59.6% of cases. The delirium period significantly differed by patients' age (F=3.96, P=0.021), cancer type (F=3.31, P=0.010), chemotherapy (t=-3.44 P=0.001). The average survival time was 16.85 days for the sedative medication group and 9.37 days for the non-medication group, which, however, was not significant (t=1.766, P=0.079). Conclusion: In this study, the use of sedatives did not affect patients' survival time. Thus, appropriate sedative medication can be positively recommended to comfort terminal cancer patients and their families.

Effects of the Elevated Temperature and Carbon Dioxide on Vine Growth and Fruit Quality of 'Campbell Early' Grapevines (Vitis labruscana) (온도와 이산화탄소의 상승처리가 포도 '캠벨얼리'의 수체생육과 과실품질에 미치는 영향)

  • Son, In Chang;Han, Jeom-Haw;Cho, Jung Gun;Kim, Seung Heui;Chang, Eun-Ha;Oh, Sung Il;Moon, Kyung-Hwan;Choi, In-Myung
    • Horticultural Science & Technology
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    • v.32 no.6
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    • pp.781-787
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    • 2014
  • The effects of elevated temperature and $CO_2$ concentration on vine growth and characteristics of fruits of three-year-old 'Campbell Early' grapevine were investigated. The treatment groups consisted of a control group (ambient temperature and $390{\mu}L{\cdot}L^{-1}\;CO_2$), an elevated temperature group (ambient temperature + $4.0^{\circ}C$ and $390{\mu}L{\cdot}L^{-1}\;CO_2$), an elevated $CO_2$ group (ambient temperature and $700{\mu}L{\cdot}L^{-1}\;CO_2$), and an elevated $CO_2$/temperature group (ambient temperature + $4.0^{\circ}C$ and $700{\mu}L{\cdot}L^{-1}\;CO_2$). The average shoot length was 312.6 cm in the elevated $CO_2$/temperature group, which was higher than the other groups; with 206.2 cm in the control group and 255.6 cm and 224.8 cm in the elevated temperature group and elevated $CO_2$ group respectively. However, the shoot diameter showed a tendency of decreasing in the elevated temperature and elevated $CO_2$/temperature groups. The equatorial diameter of berries was increased in the higher carbon dioxide concentration, and the soluble solid content was the highest in the elevated $CO_2$ group, with $14.6^{\circ}Brix$ among all treatment groups and the lowest in the elevated temperature group ($13.9^{\circ}Brix$). The harvest date was approximately 11 d earlier in the elevated $CO_2$/temperature group and 4 to 2 days earlier in the elevated $CO_2$ group and elevated temperature group, respectively. Regarding the rate of photosynthesis and transpiration during the growth period, higher photosynthetic rates were observed in the elevated $CO_2$ group and the elevated $CO_2$/temperature group during the early stage of growth; however the photosynthetic rate was reduced dramatically in summer, which was contrary to transpiration.

Study on the Utilization of Sawdust Bedding Barn for Dairy Cows (착유우의 톱밥발효우사 이용연구 제 1 보 : 낙농가의 톱밥발효우사 형태별 이용효과 비교)

  • Kweon, Du-Jung;Kweon, Ung-Gi;Ki, Wang-Seok;Lee, Kee-Jong;Han, Jeong-Dae;Jung, Suk-Chan;Kang, Seung-Won;Kang, Sang-Lyol;Jung, Hyoung-Sup;Chang, Hak-Joo
    • Journal of Animal Environmental Science
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    • v.1 no.1
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    • pp.9-19
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    • 1995
  • This study was carried out to investigate the effect of sawdust bedding barn on manure handing, management labour and physiological aspect of dairy cows, and then to establish the criteria on the optimum utilization method of sawdust bedding barn. 46 tie stall barns and 49 sawdust bedding barns were surveyed to cmopare the milk productivity between two different barns, and also 5 tie stall barns, 15 sawdust bedding barns and 1 rice hull bedding barn were selected to study the utilization situation of sawdust barn in Kyung-Ki province area. The major results obtained were as follows; 1. The roof material of sawdust barn were consisted of 66% vinyl house, 23% PVC light and 11% slate and galvanum coated tin. Most of the floor structure was earth ground with the rate of the approximately 82%. 2. The average occupied area of sawdust bed per cow was 15.2 $m^2$, depth that 30 cm and the utilization period was 12 months. 3. Milk Yield was significantly higher at sawdust barn than at tie stall barn(P<0.01). Bacterial and somatic cell count in raw milk were less at the sawdust barn than in tie stall barn. However, there was not significance difference between two barns. 4. The labour hour needed to cow management in the sawdust barn was approximately 48% of that of tie stall barn. 5. The temperature and moisture content measured in sawdust bed were closely affected by seasonal ambient temperature. The skin and hair of cow were much cleaner at the PVC light roofed sawdust barn than any other roof materials. 6. The additives used for improving of fermentation did not show any effect on temperature and moisture content in sawdust bed. When the ambient temperature was $30.4^{\circ}C$, the surface temperature of measured 1 cm above the sawdust bed was $12.2^{\circ}C$ lower and the temperature of 100 cm above the sawdust bed was $2.4^{\circ}C lower under shading net facility than that of vinyl roofed one.7. The hoof length of miking cow was 7.95 cm in tie stall and 9.19 cm in sawdust barn with high significance (P<0.01). And disease occurence such as mastitis and foot-rot tended to decrease in the sawdust barn. 8. The number of total bacteria and coliform bacteria were less in the sawdust bed compared with earth ground resting area. And a parasite strongyloides papillosus was detected but without any infected cow. 9. The nitrate($NO_3N$) content in non-roofed earth ground resting area and earth ground under the sawdust bed was likely to pollute the ground water. 10. In economic point of view, rice hull bedding barn was the cheapest among different systems. And in the sawdust bedding barn PVC light + slate roofed barn was most desirable, and vinyl roofed one the least.

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Environmental and Biological Effects at Narodo, in the Southern Water of Korea, on Bloom of Ichthyotoxic Dinoflagellates Cochlodinium polykrikoides (유해성 Cochlodinium polykrikoides 최초 발생에 관한 나로도 해역의 환경학적 특성 및 식물플랑크톤 군집 구조)

  • Cho Eun Seob
    • Journal of Life Science
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    • v.15 no.2 s.69
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    • pp.225-230
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    • 2005
  • The aim of this study was to examine the fluctuation in phytoplankton assemblages with regarding to environmental conditions and nutrients, which were surveyed quarterly over the fours seasons (February, May, July, and October). In turn, an understanding of biological effects should provide insights into a wide range of initiated Cochlodinium blooms in Narodo. Sampling was carried out throughout 2001 on the coasts of Busan (St. 1), Yeosu (St. 2), Narodo (St. 3), Kohung (St. 4), and Kwangdo (St. 5). The maximum surface water temperature was recorded in July, and it ranged from 20 to $22^{\circ}C$. Salinity showed no great variation, which maintained itself in the range of 29-34 psu. The maximum surface salinity was recorded in February, which was about 34 psu. The chlorophyll $\alpha$ concentration of the surface water ranged from 0.01 to $1.3\;{\mu}g\;1^{-1}$. The concentrations of $NH_{4}-N $ were persistently high from February to October; in particular, the peak was observed at St. 1 in February and May (0.15 and $0.19\;{\mu}mol\;1^{-1}$, respectively), while it was detected at St. 2 in July and October (0.22 and $2.2\;{\mu}mol\;1^{-1}$ respectively). Similar trends to those for $NH_4-N $ were observed in the concentrations of $NO_{2}-N$ and $NO_{3}-N$. In contrast to nitrogen, a distinct peak of $NO_{4}-P$ at St. 3, 4, and 5 was observed throughout year $(0.01-0.1\;{\mu}mol\;1^{-1}$ except for October. At St. 1 encounter a peak of cell number of 30,000 and $13{\times}10^3$ cells $1^{-1}$, respectively, in July and October. During the period of this study, the majority of the taxa were diatoms. The dinoflagellates were rather abundant after February, in particular at St. 3, 4, and 5 which attained an abundance of $10\~20\%$without marked fluctuation during the period of this study. At St. 3, the highest average cell width, $178.11\;{\mu}m$, was recorded: the highest cell length, $337.72\;{\mu}m$, was measured in July. Consequently, dinoflagellates bloom in July at Narodo influenced by warm water current are not only associated with a desirable development of cell morphometric characteristics, but also with the health growth of C. polykrikoides. During the period of this study, warm water currents caused an increased water temperature in Narodo, but did not change the amount of nutrients.

A Survey on the Effect of Crate Type and Harvest Season on Preslaughter Condition and Mortality of Broiler (어리장 형태와 계절이 육계 출하환경 및 폐사에 미치는 영향)

  • Kim Dong-Hun;Park Beom-Young;Hwang In-Ho;Cho Soo-Hyun;Kim Jin-Hyung;Lee Jong-Moon
    • Food Science of Animal Resources
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    • v.26 no.1
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    • pp.37-42
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    • 2006
  • The current study was conducted to investigate the effect of types of crate and season on transport condition and mortality, and ultimately to identify the best practice for reducing economic lose. Total loading weight stocking density, transport and lairage times and mortality were surveyed from the management data sheet of two companies for each first week of January, April, August and October, An average loading weight, length of transport and lairage times and mortality were 3.9 ton, 96 min, 478 min and 0.6%, respectively. Mortality after lairage was not significant between two types of crate. In addition, container type crate showed higher loading weight and stocking density than box type one. Spring and winter had significantly higher mortality with 0.7 and 0.8%, respectively, then summer and fell of 0.5%. An interaction between crate type and season on mortality showed that mortality for box type on was higher in spring and winter with 0.8 and 0.7%, respectively, compared to summer and fall of 0,3 and 0.4% respectively. In the case of container type crate, spring, fall and winter had greatly different death into with 0.7, 0.5 and 0.8%, respectively, while there was no difference between spring and summer, and between summer and winter, Mortality after transportation was similar between both crate type, with higher rate for spring and winder than other seasons. The result was likely related to death of exposure due to extended waiting time without heating facility.

Influence of Elevated CO2 and Air Temperature on Photosynthesis, Shoot Growth, and Fruit Quality of 'Fuji'/M.9 Apple Tree (CO2 및 기온 상승이 '후지'/M.9 사과나무의 광합성, 신초생장 및 과실품질에 미치는 영향)

  • Kweon, Hun-Joong;Sagong, Dong-Hoon;Park, Moo-Yong;Song, Yang-Yik;Chung, Kyeong-Ho;Nam, Jong-Chul;Han, Jeom-Hwa;Do, Gyung-Ran
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.15 no.4
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    • pp.245-263
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    • 2013
  • This study was conducted to find out the influence of elevated atmospheric $CO_2$ concentrations and air temperature on photosynthesis and fruit quality of 'Fuji'/M.9 apple trees and to investigate these to the effects of climate change during the last four years (2009-2012). The treatments employed were: 'Ambient' (ambient temperature + ambient $CO_2$ concentration); 'High $CO_2$' (ambient temperature + elevated $CO_2$ concentration); 'High Temp'. (elevated temperature + ambient $CO_2$ concentration); and 'High $CO_2$ + High Temp'. (elevated temperature + elevated $CO_2$ concentration). The elevated temperature plots were maintained at $4^{\circ}C$ higher than ambient air temperature, while the elevated $CO_2$ plots were maintained at 700 ${\mu}mol{\cdot}mol^{-1}$. Annual treatment period was applied from end of April to beginning of November for four years. Results showed that elevated $CO_2$ decreased stomatal conductance and leaf SPAD value, but increased photosynthetic rate, intercellular $CO_2$ concentration (Ci), and starch content of mesophyll tissue. In the vegetative growth, elevated temperature increased total number of shoot and total shoot growth per tree, but elevated $CO_2$ decreased average shoot length. In the fruit quality, elevated $CO_2$ increased soluble solid content, fruit red color, and ethylene production. In conclusion, elevated $CO_2$ increased photosynthetic rate of apples during the early growth, but effect of increased photosynthetic rate due to elevated $CO_2$ was decreased during latter growth stage. Elevated temperature, on the other hand, tended to decrease photosynthetic rate of apples during the early growth, but that tended to increase during latter growth stage. Both elevated $CO_2$ and temperature tended to decrease the degree of decreased photosynthetic rate due to each factor.

Morphometric Study on the Arterial Palmar Arch of the Hand (손바닥 동맥활에 관한 형태계측 연구)

  • Park, Bong Kwon;Jang, Soo Won;Choi, Seung Suk;Ahn, Hee Chang
    • Archives of Plastic Surgery
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    • v.36 no.6
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    • pp.691-701
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    • 2009
  • Purpose: Deviations of arterial palmar arches in the hand can be explained on the embryological basis. The purpose of this study was to provide new information about palmar arches through cadaver's dissection. The values of the location and diameter in these vessels were analyzed in order to support anatomical research and clinical correlation in the hand. Methods: The present report is based on an analysis of dissections of fifty - three hands carried out in the laboratory of gross anatomy. A reference line was established on the distal wrist crease to serve as the X coordinate and a perpendicular line drawn through the midpoint between middle and ring fingers, which served as the Y coordinate. The coordinates of the x and y values were measured by a digimatic caliper, and statistically analyzed with Student's t - test. Results: Complete superficial palmar archs were seen in 96.2 % of specimens. In the most common type of males, the superficial arch was formed only by the ulnar artery. In the most common type of females, the superficial arch was formed anastomosis between the radial artery and the ulnar artery. The average length of the superficial and deep palmar arch is $110.3{\pm}33.0mm$ and $67.9{\pm}14.0mm$ respectively. Regarding the superficial palmar arch, ulnar artery starts $-16.1{\pm}5.1mm$ on X - line, and $2.5{\pm}24.5mm$ on Y - line. Radial artery appears on palmar side $7.7{\pm}3.2mm$ on X - line, and $20.9{\pm}10.9mm$ on Y - line. But radial artery starts on $6.3{\pm}3.6mm$ on X - line, and $3.4{\pm}5.1mm$ on Y - line. Digital arteries of superficial palmar arch starts on $6.1{\pm}3.7mm$, $33.9{\pm}8.8mm$ on index finger, $1.8{\pm}3.4mm$, $40.1{\pm}7.3mm$ on middle finger, $-3.2{\pm}4.9mm$, $42.6{\pm}7.0mm$ on ring finger, and $-8.9{\pm}5.1mm$, $42.5{\pm}80mm$ on little finger in respective X and Y coordinates. Radial artery of deep palmar arches measured at the palmar side perforating from the dorsum of hand. It's coordinates were $9.7{\pm}4.8mm$ on X - line, $21.7{\pm}10.2mm$ on Y - line. Ulnar artery was measured at hypothenar area, and it's coordinates were $-20.4{\pm}6.3mm$ on X - line, and $30.6{\pm}7.4mm$ on Y - line. Conclusions: Anatomically superficial palmar arch can be divided into a complete and an incomplete type. Each of them can be subdivided into 4 types. The deep palmar arch is less variable than the superficial palmar arch. We believe these values of the study will be used for the vascular surgery of the hand using the endoscope and robot in the future.

Radiation Therapy in Elderly Skin Cancer (노령의 피부암에서 방사선치료)

  • Kim, Jin-Hee
    • Radiation Oncology Journal
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    • v.26 no.2
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    • pp.113-117
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    • 2008
  • Purpose: To evaluate the long term results(local control, survival, failure, and complications) after radiation therapy for skin cancer in elderly patients. Material and Methods: The study spanned from January 1990 to October 2002. Fifteen elderly patients with skin cancer were treated by radiotherapy at the Keimyung University Dongsan Medical Center. The age distribution of the patients surveyed was 72 to 95 years, with a median age of 78.8 years. The pathologic classification of the 15 patients included squamous cell carcinoma(10 patients), basal cell carcinoma(3 patients), verrucous carcinoma(1 patient) and skin adnexal origin carcinoma(1 patient). The most common tumor location was the head(13 patients). The mean tumor diameter was 4.9 cm(range 2 to 9 cm). The radiation dose was delivered via an electron beam of 6 to 15 MeV. The dose range was adjusted to the tumor diameter and depth of tumor invasion. The total radiation dose ranged from $50{\sim}80$ Gy(mean: 66 Gy) with a 2 Gy fractional dose prescribed to the 80% isodose line once a day and 5 times a week. One patient with lymph node metastasis was treated with six MV photon beams boosted with electron beams. The length of the follow-up periods ranged from 10 to 120 months with a median follow-up period of 48 months. Results: The local control rates were 100%(15/15). In addition, the five year disease free survival rate(5YDFS) was 80% and twelve patients(80%) had no recurrence and skin cancer recurrence occurred in 3 patients(20%). Three patients have lived an average of 90 months($68{\sim}120$ months) without recurrence or metastasis. A total of 9 patients who died as a result of other causes had a mean survival time of 55.8 months after radiation therapy. No severe acute or chronic complications were observed after radiation therapy. Only minor complications including radiation dermatitis was treated with supportive care. Conclusion: The results suggest that radiation therapy is an effective and safe treatment method for the treatment of skin cancer in elderly patients who achieved a good survival rate and few minor complications.

Effects of Post Individualities on Treatability of Small Diameter Japanese Larch (Larix Leptolepis) with ACQ and CCA (낙엽송 원주상 소경목의 원목성상과 방부 처리성)

  • Kim, Yeong-Suk;Hong, Soon-Il;Yun, Jeong-Hee
    • Journal of the Korean Wood Science and Technology
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    • v.34 no.1
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    • pp.52-60
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    • 2006
  • This study investigated how wood properties (i.e., annual rings, sapwood, heartwood, and cracks) might affect preservative treatment in Japanese larch (Larix leptolepis) round-wood product. We specially focused on small-diameter (~10 cm diameter) wood that is commercially sold in market. Among 100 wood samples, the groups of sample with 13~16, 17~20 annual rings represented 33 and 27 in each frequency, while 2~3 and 4~5 mm annual ring width accounted for 72 and 68 in frequency. More than a half (54%) of wood samples contained a mix of heartwood and sapwood in its surface. The rest (46%) had only heartwood exposed in the wood surface. A wide range of checks were showed in the wood samples, but the highest frequency was observed in samples with 1~6 surface (1~14 mm in size) checks and 1~4 end-grain (8~14 mm in size) checks in each round-wood sample. Pressure treatment resulted in a wide range of penetration of ACQ (Alkaline Copper Quat) into the wood, showing $4.3{\pm}4.19mm$ penetration in the wood samples contained a mix of heartwood and sapwood in its surface. However preservative treatment was much less effective for the heartwood only wood samples, ranging average 1.3 mm with ACQ and 1.1 mm with CCA (Chromated Copper Arsenate). These penetration results shown in heartwood samples did not meet the penetration standard that is required for H3 by the Korean Forest Service in relation to wood preservation treatment. These low penetration results were not significantly improved even if we incised wood samples to improve treatment effect, showing only small increase of 0.7 mm with ACQ and 0.6 mm with CCA. When preservative treatment was tested with heartwood, penetration of preservatives decrease with increase of annual rings per a cross-section area (r=0.5345). We also found that the length and number of check had no effect on preservative treatment, showing r=0.1301 and r=0.1802, respectively.

A Prospective Study on Emergency Room Utilization in Children with Nonsurgical Gastrointestinal Disorders (비외과적 소화기질환 환아들의 응급실 이용양상에 대한 전향적 조사연구)

  • Lee, Kyung-Ja;Tchah, Hann
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.4 no.1
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    • pp.54-62
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    • 2001
  • Purpose: There have been few reports about common gastrointestinal diseases in children visiting emergency room. The aim of this study was to present basic data and their meanings about emergency room utilization in children with nonsurgical gastrointestinal disorders. Methods: The authors prospectively studied 1,228 consecutive children with gastrointestinal diseases, amongst 6,179 nonsurgical pediatric patients who visited the emergency room of Seoul Red Cross Hospital from Jan. 1st 1998 to Dec. 31st 1999. Results: 1) First visit was 60.7% of total visits and 30.7% were between 1 and 3 years of age while 80.4% were below 6 years of age. Male patients were predominant by a ratio of 1.3:1. 2) The peak month of visits was December (12.1%), and the peak time of visits was between 8:00 pm and midnight (35.9%). Average length of stay at emergency room of the total patients were 0.86 hour. 3) Five major diseases were acute gastroenteritis (44.3%), fecal impaction &/or constipation (21.3%), acute gastritis (16.4%), intussusception (4.6%), and infantile colic (4.3%) in order. 4) 19.6% of the total patients were hospitalized. Conclusion: There were differences in various distributions regarding each nonsurgical gastrointestinal disease entity in children visiting emergency room even though distributions of the total patients in our study were not so different from those in previous reports by others.

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