• Journal of Pharmaceutical Investigation
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• 제14권3호
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• pp.105-121
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• 1984

The bioavailability of rifampicin (brand A, B and C) was studied and the dissolution by foamed plastic rotating method and basket rotating method was also investigated. The results were as follows; 1. In the case of foamed plastic rotating method, it was revealed that dissolution rate of brand C was most rapid, but in the case of basket rotating method the results revealed that brand B was most rapid. Also it was observed that the dissolution rate in artificial gastric juice was more rapid than one in artificial intestinal juice, and that Avicel added in capsule increased additively the dissolution rate, particulary brand B. 2. Relative systemic availability by urine data showed that the results from all capsules filled with brand A, B and C were identical but in the case of the ripamficin capsules filled with Avicel, the results showed that Avicel increased the availability of brand A and B. 3. Area under serum concentration curve $(0{\sim}8hrs)$ was in order of $brand\;A{\fallingdotseq}brand\;C$ > brand B, but Avicel increased significantly the AUC of brand B and showed no effect in others. 4. Relative systemic availability calculated with excreted amount of rifampicin in urine was similar in each rifampicin capsules. In rifampicin (A) and rifampicin (B), Avicel which added in capsules appeared increasing tendency in urine excretion of rifampicin, but in rifampicin (C) it did not appeared. 5. Area under serum concentration curve $(0{\sim}8hrs)$ in rifampicin capsules was in order of $rifampicin(A){\fallingdotseq}rifampicin(C)$>rifampicin(B). In rifampicin (B) with Avicel capsules, area under serum concentration curve (0-8hrs.) increased significantly and in others insignificantly.

• 한국정보처리학회논문지
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• 제2권6호
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• pp.985-994
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• 1995

본 논문에서는 높은 시스템 가용성을 제공할 뿐만 아니라 고장 발생시 데이타 손실이 없는 두 가지 hot standby 구조를 제안한다. 제안된 hot standby 구조의 성능 을 평가하기 위해서 hot standby 구조로부터 동기 unit 만을 제거한 warm standby 구 조를 고려하였으며, 각 구조에 대한 시스템 불가동률을 마르코프 상태도를 이용하여 구한 후 서로 비교 평가하였다. 본 연구 결과, 대부분의 경우 hot standby 구조가 warm standby 구조보다 훨씬 높은 가동률을 제공하였으며, 외부 동기 unit로 구성된 hot standby 구조가 내부 동기 unit로 구성 된 hot standby 구조보다 향상 약간 높은 시스템 가동률을 유지하였다. 각 구조에 대한 active set time과 personnel recovery rate 는 시스템 가동률에 거의 영향을 미치지 않았다. 그러나 data recovery time 이 임계치 이상으로 증가하는 경우에는 hot standby 구조와 warm standby구조 모두 시스 템 가동률이 급격히 저하되었고 특히 hot standby 구조의 성능 저하가 심하여 궁극적으로 warm standby 구조보다 시스템 가동률이 떨어지는 현상을 보였다.

• Journal of Nutrition and Health
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• 제26권6호
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• pp.783-792
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• 1993

This study examined the difference in growth rate between Korean breast-fed(BF) and formula-fed(FF) infants(n=31) at 1, 2 and 3 months postpartum. The results indicated that the growth rate was comparable between groups, but that of the BF infants tended to be slow during the first three months. The intakes of energy, protein and lipid except lactose of the FF infants were greater than those of the BF infants, however the difference in growth rate did not correlate to these variables. But these results suggest that the availability of nutrients might be different between the BF infants and the FF infants.

• 대한기관식도과학회지
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• 제7권2호
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• pp.161-167
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• 2001

Background and Objectives： Total laryngectomy is often required for advanced cases. But this operation induced the many inconvenience of basic daily life. Early diagnosis of laryngeal cancer is very important to prevent from this disastrous condition. In this point of view, mass screening test for early detection of laryngeal cancer is necessary. Screening test using voice has many advantages such as simple, less interventional. Voice collection by Automatic Response System(ARS) is comfortable and easy to got acoustic sample. Thus author tried to got the acoustic parameters which can differentiate normal, benign. and malignant laryngeal diseases and also checked the availability of parameters on neural network system. Materials and Methods: Author has evaluated the voice from 17 laryngeal cancer patients and 45 benign laryngeal disease patients who visited at Department of Otolaryngology, Pusan National University Hospital from May 1998 to April 2001, and 15 normal control. Author chose the sir Parameters (Jitt. vFo, Shim, vAm, NHR, SPI) that was thought to be related with voice collected by ARS among thirty-three parameters analysed by a Multi-Dimensional Voice Program (MDVP). Two-step neural network was used for the availability of six parameters. Results: The detection rate of normal voice by ARS voice analysis is 78.5% and detection rate of abnormal voice was 97.1 o/o. Among abnormal voice, the detection rate of benign laryngeal diseases and laryngeal cancers were 82.4 o/o, 70.6% respectively. Conclusion: Author concluded that six parameters and Matlab based neural network software may be effective in development of acoustic screening system for laryngeal cancer and further study should be necessary for development of new acoustic parameters.

• 대한산업공학회지
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• 제39권6호
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• pp.599-608
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• 2013

This study is intended to propose optimal maintenance organization to process industry, especially paper industry by analyzing maintenance organization of paper industry and finding out how the maintenance organization and the allocation of maintenance resources influence maintenance performance indices here in this paper. In this study, we analyzed the maintenance organization in detail and studied correlation between maintenance organization and equipment failure rate for the major top six domestic paper-mills in market share. According to the study, the maintenance organization has been changed in accordance with its business environment, but its performance was different by both the allocation way of maintenance resources and the structure of maintenance organization. For paper industry, whose availability is the most important key index that determines the success or failure of a business, it turns out to be the most effective strategy that operates the combination maintenance combined central maintenance with area maintenance and allocates the maintenance resources mainly for preventive maintenance. In particular, it turned out to be that there is the strong positive correlation between the rate of shift workers and the equipment failure rate. The results of this study is not limited to paper industry, but expandable to other industry. So it is expected that the direction of the maintenance organization would be given to the company which is struggling to improve its availability.

• 한국항해항만학회지
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• 제45권5호
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• pp.259-275
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• 2021

This study analyzed the decision-making process in ship finance for the choice between fixed and floating interest rates using behavioral finance theories. Results confirmed that causes and background of decision-making processes could be explicitly explained by the framework of behavioral finance theories. This study also determined whether decisions were irrational. A case-study research was applied as the methodology. Decision-making data on ship finance collected through narrative and questionnaire responses were analyzed and evaluated using behavioral finance theories. Theories of behavioral finance used in the analysis and research of this study included availability heuristic, anchoring effect, and opportunity cost theory. Narrative and survey responses were clearly explained by theories of behavioral finance. It was found that a shipping company suffered additional losses owing to decisions that included behavioral finance errors. Behavioral finance theories largely influenced the decision-making process of choosing between a fixed interest rate and a floating interest rate. Shipping finance decisions related to interest rate selections could be clearly explained by behavioral finance theories. Errors related to behavioral finance could result in irrational decisions. Thus, managers who are responsible for shipping finance should remain vigilant toward any behavioral finance errors when making shipping finance decisions.

• 정보보호학회논문지
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• 제23권2호
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• pp.279-286
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• 2013

최근 전력 수요의 급증으로 인한 전력난은 효율적 전력 사용을 위한 스마트그리드 기술의 중요성을 부각시키고 있다. 스마트그리드 네트워크의 필수구성요소인 스마트미터기의 가용성 취약점에 대한 실험적 내용이 보고되고 있다. 따라서 안전한 스마트그리드의 실현가능성을 위한 가용성 보호 메커니즘 고안이 필수불가결하다. 본 논문에서는 스마트그리드 구조 및 트래픽패턴의 특징 분석을 통해 스마트미터기에 대한 가용성 침해 공격을 탐지하고, 이상 트래픽을 발생하는 공격노드를 검출할 수 있는 메커니즘을 제안한다. 제안하는 탐지 메커니즘은 공격 탐지를 수행하는 시스템의 탐지 부하를 줄이고 적은 샘플 수에도 높은 탐지율을 제공하기 위해 근사엔트로피 기법을 사용한다. 또한 공격노드가 공격트래픽에서 변경할 수 없는 물리정보(CIR 또는 RSSI 등)를 이용하여 공격 탐지 및 공격노드 검출을 수행한다. 마지막으로 본 논문 제안 기법에 대한 시뮬레이션 결과, 탐지 성능과 실현가능성을 보인다.

• 대한안전경영과학회지
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• 제10권3호
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• pp.89-98
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• 2008

A preventive maintenance model, caller FNBM($\alpha$, $\delta$, $\gamma$)model, is proposed to decide an optimal repair number under achieved availability requirements(r) along with taking two types of failures (repairable or irrepairable) into account. In this model, the current system is replaced by a new one in case when it doesn't meet the achieved availability requirement, even though it is repairable failure; Otherwise it is replaced in time of the first irrepairable failure. Assumed that the j-th failure is repairable with probability ${\alpha}_j$ minimal repairs are allowed for repairable failure between replacements. Expected cost rate for preventive maintenance model is developed using NHPP(Non-Homogeneous Poisson Process) in order to determine the optimal number $n^*$, also numerical examples are shown in order to explain the proposed model. Since the proposed FNBM($\alpha$, $\delta$, $\gamma$)model includes Park FNBM model(1979) and Nakagawa FNBM(p)model(1983) this proposed model is thought to be better than previous model, especially for weapon system which requires availability as primary parameter.

• 한국작물학회지
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• 제38권5호
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• pp.458-465
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• 1993

양액재배를 통하여 질소가급도와온도 및 수분부족 조건에 따른 유모기 보리의 질소 흡수 및 동화와 생장의 변화를 조사하였던 바, 그 결과를 요약하면 다음과 같다. 1. 보리의 질소 흡수량은 양액의 질소가급도가 160ppm까지 높아질수록 증가하였으나 흡수된 질소의 동화는 80ppm에서 최고에 달하였고, 이보다 높아졌을 때는 체내에 무기능질소로 축적되었다. 2. 유묘기(3～4엽기)보리의 질소동화 및 건물생산은 엽중 질소농도가 약 3.4%일 때 최고에 달아혔다. 3. 유묘기 보리의 질소 흡수는 -2bar 이하의 수분 포텐셜 조건 또는 5$^{\circ}C$이하의 온도조건에서 현저히 감소하였다.

• 한국환경농학회지
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• 제23권2호
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• pp.104-110
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• 2004

이화학적 특성이 다른 4가지의 밭토양에 대한 규산질 비료를 처리하여 토양의 유효규산 함량과 pH 변화에 미치는 효과를 조사하였다. 토양의 이화학적 특성과 기존 유효규산 함량에 상관없이 토양 유효규산 함량은 규산질 비료 시용량에 비례하여 증가하였다. 규산질 비료의 유효화 정도는 토양마다 차이가 있었으며 최저 9.1%에서 최고 19.2% 정도의 비율을 나타냈다. 규산질 비료 100 kg/10a 수준의 처리는 용탈 등으로 제거되지 않는 한 10 cm 질이 표토에 평균적으로 100 mg/kg 정도의 유효규산을 공급할 수 있는 것으로 나타났다. 퇴비 혼합처리는 토양 유효규산 함량 증가에 큰 영향을 미치지 못했으며, 석회 처리는 유효규산 함량을 다소 증가시켰다. 토양 pH 변화는 모든 토양에서 규산질 비료 시비량에 비례하여 증가하였으며, 규산질 비료 100 kg/10a 처리로 토양 pH를 $0.1{\sim}0.2$ 단위 증가시킬 수 있는 것으로 나타났다. 따라서 산성 토양의 경우에는 규산질 비료의 시용과는 별도로 pH 교정을 위해 석회비료를 시용해야 할 것이다.