• 한국동물위생학회지
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• 제32권4호
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• pp.391-397
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• 2009

Eurasian eagle owl (Bubo bubo kiautschensis) is a natural monument (No. 324) and is also classified as an endangered wildlife grade II the Ministry of Environment of Korea. Eurasian eagle owl is threatened by the human being. But the efficient rescue and treatment for Eurasian eagle owl are still problematic, due to lack of basic data. In this study, to obtain basic resources for establishing more efficient rescue system, we held a physical examination and measured size physical part. In addition, we analyzed blood sample and feces samples and autopsy. We conduct the physical examination with measuring tapes and scales for 16 live features and 11 dead features. After inhalation anesthesia take the blood samples from wing vein. Blood samples are analyzed in hematologic and chemistric methods. We collected the feces through individual floor of cages from 12 live features and conducted the feces analysis. Autopsy was conducted for 11 dead samples. In physical examination, the mean body weight and total length of live features was 2.26${\pm}$0.35kg, 61${\pm}$2.38cm, the mean body weight and total length of dead features was 1.57${\pm}$0.51kg, 59.31${\pm}$3.51cm. Mean PCV was 46.57${\pm}$4.97%, while mean TPP was 3.49${\pm}$0.57g/dL. In feces sample analysis, 9 of 12 owls(75%) were infested by gastrointestinal helminths. The infection rates were: Trematoda (41.7%), Capilaria sp.(66.7%), acanthocephalans (25%). In autopsy, we confirmed 11 features were infested by duplicated infection of more than 2 helminths. Result of this study will be used for establishing reference range for physical features, blood analysis in Eurasian eagle owl. Therefore, to obtain basic resources for establishing more efficient rescue system, we have to make long-term conservation plans for Eurasian eagle owl.

• 대한예방한의학회지
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• 제15권1호
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• pp.37-47
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• 2011

Objectives : Previous studies have shown that Fructus mume (FM) has anti-platelet effects. The present study was performed to determine the acute oral toxicity and quality control of a crude extract of FM in ICR mice. Methods : We investigated the in vivo single dose acute toxicity of FM 95% ethanol extract. This test was orally administered once by gavage to 20 male and 20 female mice at dose levels of 0 (control group), 1250, 2500 and 5000mg/kg body weight, respectively. Mortalities, clinical findings, autopsy findings and body weight changes were monitored daily for the 14 days following the administration. HPLC analysis was performed for the simultaneous determination of ursolic acid and p-hydroxycinnamic acid in FM. Reverse-phase chromatography using a C18 column and photodiode array detection at 211 nm was used for quantification of the two maker components. The mobile phase for gradient elution consists of water and acetonitrile. Results : We observed survival rates, general toxicity, change of body weight, and autopsy. The mice did not die after single oral administration of maximum dose of FM. Autopsy of animal revealed no abnormal gross finding. Therefore, $LD_{50}$ value of FM for ICR mice was more than 5000mg/kg on oral route. The HPLC analysis showed that ursolic acid and p-hydroxycinnamic acid amounts to 9.75- and 0.12% in the extract with the retention times of 47.99- and 15.38 minutes, respectively. Conclusions : These results suggest that no toxic dose level of FM in mice is considered to be more than 5000mg/kg. Consequently, it was concluded that FM have no effect on acute toxicity and side effect in ICR mice. For the quality control of FM extract, simultaneous determination of ursolic acid and p-hydroxycinnamic acid was established.

• Toxicological Research
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• 제11권1호
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• pp.133-136
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• 1995

HRccine(HFRS-virus vaccine) was administered subcutaneously or intragastrically to Spargue Dawley rats and subcutaneously to Japanese white rabbits to investigate the acute toxicity. $LD_50$ values were above 600 times the expected clinical dose in both animals. There were no differences in body weight changes, clinical signs and autopsy findings between all treated groups and control group in both animals. Therefore, it was concluded that HRccine is a very safe substance.

• 한국임상수의학회지
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• 제16권1호
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• pp.235-238
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• 1999

Two Jindo dogs which show clinical signs of anorexia, weakness and exercise intolerance, were referred, and diagnosed as dirofilariasis by hematology, blood chemistry and ultrasonography. In hematology and blood chemistry, the presence of microfilariae in the blood, anemia, leukocytosis, hemoglobinuria and jaundice were revealed. In ultrasonography, heartworms were found in the right ventricle artery and pulmonary artery as structures of hyperechoic dots or streaks. In autopsy, forty odd and fifty odd of heartworms at dog 1 and dog 2, were ascertained respectively in the right ventricle and pulmonary artery.

• Journal of Chest Surgery
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• 제17권3호
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• pp.537-542
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• 1984

Bronchogenic cysts were considered rare entities but many have recently been discovered in mass roentgenographic surveys of the chest and autopsy. Their origin were considered might be congenital or developing process. The treatment of bronchogenic cyst is surgical resection. Thirteen cases of bronchogenic cysts which were confirmed by pathologically, were operated in the Thoracic & Cardiovascular Surgery Department of Catholic Medical College and reported with related literature.

• 한국환경보건학회:학술대회논문집
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• 한국환경보건학회 2006년도 Perspectives of Evironmental Health Issues in Asia-Pacific Region
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• pp.47-72
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• 2006

• Journal of Chest Surgery
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• 제12권3호
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• pp.240-246
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• 1979

A 15-year-old boy having a small VSD was readmitted with clinical manifestations of acute endocarditis and aortic regurgitation one month after open heart surgery. In spite of vigorous treatment with broad-spectrum antibiotics, high fever persisted. Pseudomonas aeruginosa was isolated just one time among several blood cultures. Progressive pulmonary infarction due to embolization. Progressive congestive heart failure and D.I.C. caused patient`s death. Aspergillus was found in autopsy specimen.

• 대한수의사회지
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• 제8권5호
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• pp.3-11
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• 1964

These reports are based upon the postmortem examination of wild animals obtained at Chang Kyung won zoo in Seoul since 1955 when the zoo was restored gradually after Korean war . $\cdot$ Formosan Deer(female, 12year-old) Primary adenocarcinoma

• 대한수의학회지
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• 제14권1호
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• pp.45-48
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• 1974

Four water monitors at Zoological Garden, Chang Gyeong Won, Seoul, died within a week after signs of anorexia, lethargy, and discharge from eyes, nasal and oral cavities. The autopsy findings of the four animals were similar. As a main lesion, the liver was congested and diffuse necrosis was observed. The terminal portions of the rectum were studded with numerous small ulcers causing rectal stenosis. Histopathologically, massive hepatic necrosis preceded by fatty changes were evident. The rectal lesions manifested coagulative necrosis and thrombosis in the mucosa and submucosa.

• 한국임상수의학회지
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• 제10권1호
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• pp.131-135
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• 1993

In this case, Grant's Zebra which had been bred and exhibited in Farmland Zoological Garden for 4 years, died after treated dystocia. Result in autopsy, she had large hepatic abscess, and blood chemistry were increased G07, GPT and total billirubin. The microbiological culture with the hepatic abscess idetified the Streptococcus equi. It is diagnosed of hepatic abscess which was caused by Streptococcus equi infection.