• 대한약침학회지
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• 제11권1호
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• pp.83-97
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• 2008

Objectives : We investigated the effects of distilled Rehmannia glutinosa Herbal Acupuncture on autonomic nervous system with the Heart Rate Variability(HRV) in adult man. as well as we tried to observe how distilled Rehmannia glutinosa Herbal Acupuncture on the balance of the autonomic nervous system. Methods : We investigated on 58 healthy volunteers consisted of 28 subjects in experiment(distilled Rehmannia glutinosa Herbal Acupuncture) group and 30 subjects in control(Normal Saline) group. Study form was a randomized, placebo-controlled, double-blind clinical trial. 28 subjects in experiment group were injected distilled Rehmannia glutinosa Herbal Acupuncture at $GB_{21}$(Kyonjong) and 30 subjects in control group were injected Normal Saline at $G_{21}$(Kyonjong). except of 2 subjects(in control group) who can't be measured and 6 subjects(2 in experiment group and 4 in control group) who move or make unforceable error during measuring. Finally 26 subject in experiment group and 24 subject in control group are studied. We measured HRV by PolyG-I on 7 times : before and after injection per 5 minutes during 30 minutes. The SPSS 10.0 for windows was used to analyze the data and the paired t-test(in group) and Student t-test(between two groups) were used to verify the result. Results : 1. After distilled Rehmannia glutinosa Herbal Acupuncture injection, Mean HRV is significantly low only for first 5 minute, SDNN is significantly high after 5 minute, Complexity is significantly low only from 20 minute to 25 minute. HRV index is significantly high for first 5minute and from 10 minute to after 10 minute. 2. HRV index of distilled Rehmannia glutinosa Herbal Acupuncture Group significantly increased from 25 minute to 30 minute, and pNN50 of Rehmannia glutinosa Herbal Acupuncture Group significantly decreased from 20 minute to 30 minute compared with those of Normal Saline group. 3. After distilled Rehmannia glutinosa Herbal Acupuncture injection, Ln(TP) and Ln(VLF) are significantly high after injection. Normalized LF is significantly high from 5 minute to 20 minute and from 25 minute and 30 minute. Normalized HF is significantly low from 5minute to 20 minute and from 25 minute and 30 minute. 4. Ln(TP) and Ln(VLF) of distilled Rehmannia glutinosa Herbal Acupuncture Group significantly increased from 20 minute to 25 minute compared with those of Normal Saline group. Conclusions : The results suggest that Rehmannia glutinosa Herbal Acupuncture in healthy adult man tend to activate the autonomic nervous system and parasympathetic nervous system compared to Normal Saline within normal range.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 합동 추계학술대회 논문집 정보 및 제어부문
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• pp.403-406
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• 2002

Autonomic nervous system keep the balance of internal environments against internal and external environment changes which affect the presence. These works play an important role of keeping our health as balancing homeostasis. But the abnormality of these abilities makes our presence feeble. To obtain these information of body, this paper will propose system-measure model which decides whether one is health or not, studying Heart Rate Variability.

• Safety and Health at Work
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• 제13권2호
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• pp.148-154
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• 2022

Background: Bus driving is a mentally demanding activity that requires prolonged attention to ensure safety. The aim of the study was to assess mental fatigue caused by driving a public bus and to find a profile of workers at higher risk. Methods: We evaluated changes of critical flicker fusion (CFF) (index of central arousal) and heart rate variability (HRV) (index of autonomic balance) in a 6-hour driving shift on a real route, in 31 professional bus drivers, and we tested the influence of personal factors such as sleep quality, BMI, and age. Paired t-test was used to test differences of CFF and HRV between both initial and final phase of driving, while multiple linear regression tested the influence of personal variables on the indexes of mental fatigue. Results: Results showed that CFF significantly decreased after 6 hours of bus driving (41.91 Hz, sd 3.31 vs. 41.15 Hz, sd 3.15; p = 0.041), and heart rate significantly decreased in the final phase of driving, with respect to the initial phase (85 vs. 78 bpm, p = 0.027). Increasing age (beta = -0.729, p = 0.022), risk of obstructive sleep apnea syndrome (beta = -0.530, p = 0.04), and diurnal sleepiness (beta = -0.406, p = 0.017) showed a significant effect on influencing mental fatigue. Conclusion: Elderly drivers at higher risk of sleep disorders are more prone to mental fatigue, when exposed to driving activity. Monitoring indexes of central arousal and autonomic balance, coupled with the use of structured questionnaires can represent a useful strategy to detect profile of workers at higher risk of mental fatigue in such duty.

• Journal of Acupuncture Research
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• 제29권4호
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• pp.43-53
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• 2012

Objectives : This study was accomplished to investigate the effects of moxibustion at Jeonjung($CV_{17}$) on the heart rate variability(HRV) in healthy adults. And based on that, we tried to find out how moxibustion at Jeonjung($CV_{17}$) effects on the activity and balance of the autonomic nervous system Methods : We investigated on 50 healthy volunteers consisted of 24 subjects in moxibustion group and 24 subjects in control group. On the other hand, two volunteers were ruled out by standard of elimination. The study was established by randomized trial. Moxibustion was applied at Jeonjung($CV_{17}$) and rested during 10 minutes in moxibustion group. No treatment was executed in control group. We measured HRV 3 times : baseline measurement and after treatment in moxibustion group(after rest in control group) twice. The SPSS 12.0 for windows was used to analyze the data by paired t-test, Wilcoxon signed ranks test(in group) and Independent t-test, Mann-Whitney U-test (between the groups). Results : 1. In moxibustion group, mean HRT decreased significantly. Ln(VLF) increased significantly. Ln(TP) decreased significantly at $2^{nd}$ time and increased significantly at $3^{rd}$ time. SDNN, RMSSD, PSI, Ln(LF), Ln(HF), Normalized LF, Normalized HF and LF/HF ratio were not affected. 2. In control group, PSI and normalized HF decreased significantly. SDNN, Ln(TP), Ln(VLF), normalized LF and LF/HF ratio increased significantly. Mean HRT, RMSSD, Ln(LF) and Ln(HF) were not affected. Conclusions : This study suggest that moxibustion at Jeonjung($CV_{17}$) makes no effects on the balance of the autonomic nervous system.

• 사상체질의학회지
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• 제19권3호
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• pp.176-187
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• 2007

1. Objectives The purpose of this research is to find out the Sasang Constitutional difference in Heart Rate Variability. 2. Methods We enrolled 8498 workers who tested for Heart Rate Variability(HRV) from September 1, 2005 to November 28, 2005 except works whose body constitusions were undetermined according to QSCCII. 3. Results & Conclusions The result of HRV of autonomic activity and stress resistance were arranged in the order of Soeumin, Soyangin and Taeumin. On the other hand Stress Index and Fatigue Index were arranged in the order of Taeumin, Soyangin and Soeumin. But autonomic balance was no significance relationship between Sasang Constitutions. This research has shown that there is a statistical significance between the HRV and Sasang Constitutions. The findings indicated that HRV could be useful mean to make a diagnosis of Sasang Constitution or apprehended Constitutional differences.

• Journal of Korean Biological Nursing Science
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• 제11권1호
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• pp.32-41
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• 2009

Purpose: This study was to identify the effects of aroma inhalation therapy on heart rate variability and anxiety in the context of urodynamics study. Method: The data were collected from 64 patients who were receiving urodynamics at the C University Medical Center in Seoul, 23 in the experimental group, 22 in the placebo group and 19 in the control group. In the experiment, the subjects of the experimental group inhaled a mixture of lavender and bergamot for 5 min, the subjects of the placebo group inhaled geranyl acetate oil for 5 min and the subjects of the control group relaxed for 5 min. The instruments used in this study included the state anxiety inventory and heart rate variability. Result: The score of state anxiety was no significant differences between the three groups after aroma-inhalation. Also, the sympathetic nerve activity and parasympathetic nerve activity was no significant differences between the three groups after aroma-inhalation. Autonomic nerve balance was maintained significantly in the experimental group as compared to the control groups after aroma-inhalation. Conclusion: The aroma inhalation therapy was very effective in balancing the autonomic nervous system in the patients undergoing urodynamic study.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.406-409
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• 1997

In this paper, the power spectral analysis and fractral dimension analysis of heart rate variability(HRV) were performed to evaluate effects of orthostatic stress with head-up tilt on autonomic nervous system(ANS) for 24 young and healthy subjects(age: $24{\pm}5yr$.). The ECG and respiration signals were recorded at the tilt angle of $0^{\circ},\;15^{\circ},\;30^{\circ},\;45^{\circ},\;70^{\circ}$ and $90^{\circ}$ successively for 5 minutes per each stage under the condition of frequency controlled respiration (0.25Hz). Heart rate(HR) gradually increased as the angle increased. Similarly, according to the increment of angle, normalized low frequency(LF) component(0.05-0.15Hz) gradually increased, whereas normalized high frequency(HF) component (0.20-0.30Hz) was reduced. From these results it is speculated that orthostatic stress, head-up tilt, results in the prevalence of sympathetic tone in autonomic balance with the increment of sympathetic tone and the decrement of parasympathetic tone, which seems to mean that autonomic nervous system plays a major role in compensating for disturbances of cardiovascular system due to it.

• 대한의용생체공학회:의공학회지
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• 제33권3호
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• pp.141-147
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• 2012

In this paper, we have investigated effects of two specific meditations (Chinese qigong meditation and Kundalini yoga meditation) on the heart rate variability (HRV), which is a well-known quantitative measure of autonomic balance, of skilled students. To analyze the effects, the MIT/BIH physionet database was utilized. The database includes RR intervals of eight skilled Chinese qigong meditators (5 women and 3 men; age range 26-35) and four skilled Kundalini yoga meditators (2 women and 2 men; age range 20-52). RR intervals of each subject were measured before and during the meditations. For HRV analysis, we have used typical four HRV parameters - the low frequency to high frequency power ratio (LF/HF ratio), SD2/SD1 ratio, sample entropy, and fractal dimension. The LF/HF ratio was calculated by the autoregressive spectrum and the SD2/SD1 ratio was derived from the Poincar$\grave{e}$ plot. The sample entropy was computed from the phase space plot and the fractal dimension was estimated by the Higuchi's algorithm. In the experiments, the Wilcoxon signed rank test was employed because we used small datasets and compared HRV parameters before and during the meditations. As a result, we have found increment of the LF/HF and SD2/SD1 ratios in both meditations; whereas the sample entropy is decreased during the meditations. In addition, the fractal dimension is increased during the Chinese qigong meditation; whereas it is decreased during the Kundalini yoga meditation. The results show that the sympathetic nervous system is generally more activated in skilled Chinese qigong and Kundalini yoga meditators, but the activation of the parasympathetic nervous tone is suppressed.

• 대한의용생체공학회:의공학회지
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• 제14권4호
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• pp.349-354
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• 1993

To investigate the relations between the physical constitutions, the acid-base balance, and the autonomic nervous function, the blood gas, the heart rate and the concentrations of Na, K of serum were measured pre-and poststimulation. As the result, it is shown that in the normal condition the macro-negative(strong liver- weak lung type) is the metabolic alkalosis, the macro-positive (strong lung-weak liver type) is the metabolic acidosis, the micro-negative(strong kidney-weak spleen type) is the alkalosis and the micro-positive (strong spleen-weak kidney type) is the acidosis. And the ntacro-positive and micro-positive are the sympathetic lead, the macro-negative and micro-negative are the parasympathetic lead. In the macro-positive and micro-positive subjects, the concentration of K in serum is relatively high. This si coincided with the acidosis. But in the macro-negative and micro-negative subjects, the concentration of K in serum is relatively low. This is coincided with the alkalosis.

• Journal of Dental Anesthesia and Pain Medicine
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• 제24권4호
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• pp.273-283
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• 2024

Background: This study evaluated the effect of remimazolam and propofol on changes in autonomic nerve activity caused by surgical stimulation during orthognathic surgery, using power spectrum analysis of blood pressure variability (BPV) and heart rate variability (HRV), and their respective associations with cardiovascular fluctuations. Methods: A total of 34 patients undergoing Le Fort I osteotomy were randomized to the remimazolam (Group R, 17 cases) or propofol (Group P, 17 cases) groups. Observables included the low-frequency component of BPV (BPV LF; index of vasomotor sympathetic nerve activity), high-frequency component of HRV (HRV HF; index of parasympathetic nerve activity), balance index of the low- and high-frequency components of HRV (HRV LF/HF; index of sympathetic nerve activity), heart rate (HR), and systolic blood pressure (SBP). Four observations were made: (1) baseline, (2) immediately before down-fracture, (3) down-fracture, and (4) 5 min after down-fracture. Data from each observation period were compared using a two-way analysis of variance with a mixed model. A Bonferroni multiple comparison test was performed in the absence of any interaction. One-way analysis of variance followed by Tukey's multiple comparisons test was performed when a significant interaction was observed between time and group, with P < 0.05 indicating statistical significance. Results: Evaluation of autonomic nerve activity in comparison with baseline during down-fracture showed a significant increase in BPV LF (P < 0.001), an increasing trend in HRV LF/HF in Group P, and an increasing trend in HRV HF in Group R. There were no significant differences in HR or SBP between the two groups. Conclusion: During down-fracture of Le Fort I osteotomy, sympathetic nerve activity was predominant with propofol anesthesia, and parasympathetic nerve activity was predominant with remimazolam anesthesia.