• 한방안이비인후피부과학회지
• /
• 제24권3호
• /
• pp.65-73
• /
• 2011

Background : There are findings indicating that the autonomic nervous system (ANS) is affected negatively in atopic dermatitis (AD). Heart rate variability (HRV) is a tool to examine ANS. But, studies investigation the relationship between AD and HRV is rare. Objective : The aim of this study was to investigate the correlation between atopic dermatitis severity and HRV and to find out the role of ANS in AD. Methods : Retrospective chart review was performed. The Severity Scoring Atopic Dermatitis (SCORAD) index and HRV parameter was investigated and analyzed. Results : There were 55 patients (25males and 30 females) who met the criteria. Objective SCORAD had significant positive correlation with HRT and Subjective SCORAD had significant negative correlation with SDNN, TP and VLF. Intensity item of SCORAD index had negative correlation with most HRV parameters, but TP, LF and LF/HF ratio had significant positive correlation with dryness. Conclusion : This study supports the concept that atopic dermatitis is a stress-responsive disorder and involves autonomic nervous system dysfunction.

• Clinical and Experimental Pediatrics
• /
• 제59권11호
• /
• pp.451-455
• /
• 2016

Purpose: Neurocardiogenic syncope (NCS) is the most frequent cause of fainting during adolescence. Inappropriate cardiovascular autonomic control may be responsible for this clinical event. The head-up tilt test has been considered a diagnostic standard, but it is cumbersome and has a high false-positive rate. We performed a study to evaluate whether P-wave dispersion (PWD) could be a useful electrocardiographic parameter of cardiac autonomic dysfunction in children with NCS. Methods: Fifty-four patients with NCS (28 boys and 26 girls; mean age, $12.3{\pm}1.4$ years) and 55 age- and sex-matched healthy controls were enrolled. PWD was obtained as the difference between maximum and minimum durations of the P wave on standard 12-lead electrocardiography in all patients and controls Results: The value of PWD was significantly higher in the syncope group than in the control group ($69.7{\pm}19.6$ msec vs. $45.5{\pm}17.1$ msec, respectively; P<0.001). The minimum duration of P wave was shorter in the syncope group than in the control group ($43.8{\pm}16.8$ msec vs. $53.5{\pm}10.7$ msec, respectively; P<0.001). Left atrial volume was not different between the groups on transthoracic echocardiography. Conclusion: PWD on echocardiography could be used as a clinical parameter in patients with NCS.

• 대한한방부인과학회지
• /
• 제24권3호
• /
• pp.109-115
• /
• 2011

Objectives: To characterize autonomic dysfunction in patients with Cold hypersensitivity, their heart rate variability(HRV) were measured and analyzed with cold hypersensitivity patients, compared with those of normal population. Methods: We studied 56 patients visiting Gangnam Kyung-hee korean hospital from 1st January 2010 to 31th December 2010. Heart rate variability were obtained from 28 female patients who suffer from cold hypersensitivity and 28 healthy female controls in resting state. We studied the difference of Heart rate variability between two groups by Independent T-test using SPSS for windows(version 17.0). Results: Standard deviation of NN interval(SDNN), total power(TP), Very low frequency(VLF) in patients with cold hypersensitivity were significantly different with those of controls. While no significant differences were observed in square root of mean squared differences of successive NN intervals (RMSSD), low frequency (LF) and high frequency(HF). Conclusions: The decreased values of heart rate variability(HRV) study means that they may have some kinds of imbalance in autonomic nervous system in cold hypersensitivity patients. heart rate variabiliry(HRV) study might be a tool of diagnosis and predictors in cold hypersensitivity patients.

• 대한한방내과학회지
• /
• 제19권2호
• /
• pp.7-16
• /
• 1998

Background and Purpose The increasing evidence for neurally mediated cardiac damage and sudden death has focused attention on the central autonomic control of cardiac function. Power spectral analysis of heart rate variability(HRV) can detect autonomic consequences of stroke. We performed power spectral analysis of heart rate variability from 24-hour holter recording to identify cerebral hemispheric lateralization and gender effect in cardiac autonomic control. Methods Data were obtained from 24-hour holter recordings in 30 consecutive patients with hemispheric brain infarction in the subacute phase. We analysed the time domain and frequency domain measures of HRV and ST segment by hemispheric lateralization and Gender. Results ST segment was depressed in women compared with man. There was no statistically significant differences between right and left hemisphere stroke patients in any standard index of HRV and ST segment changes. Conclusions These data are partial consistent with evidence from the recent literature that two cerebral hemispheres and gender have a differential influence on the nature and severity of cardiac dysfunction. We think the prospective and definite study was necessary.

• 한방재활의학과학회지
• /
• 제19권2호
• /
• pp.241-250
• /
• 2009

Objectives : To study autonomic nervous system dysfunction of Low Back Pain(LBP) patients, using spectral analysis of Heart Rate Variability(HRV). Methods : HRV of 190 patients was measured and seperated into two groups, those with LBP(n=95) and healthy controls(n=95). HRV was measured by SA-6000(Medicore, Korea) for 5 minutes after 5 minutes' resting. Results : 1. Mean heart rate(MHRT) of the experimental group was slightly higher than that of the control group, but did not show significant difference(P=0.428). The square root of the mean squared differences of successive normal-to-normal intervals(RMSSD), logarithmic very low frequency power(Ln VLF) and low frequency power/high frequency power ratio(LH/HF ratio) were not significantly low between experimental group and control group(P=0.16, 0.130, 0.537). 2. The standard deviation of all the normal-to-normal intervals(SDNN), logarithmic total power(Ln TP), logarithmic low frequency power(Ln LF) and logarithmic high frequency power(Ln HF) were significantly low between experimental group and control group(P=0.03, 0.005, 0.001, 0.007). 3. Ln LF of acute group was significantly low compared with those of chronic group(P= 0.039). Conclusions : This study suggests the activity and imbalance of autonomic nervous system in LBP is low. Also sympathetic nervous system of acute LBP is lower than that of chronic LBP. Further study of HRV related to LBP is needed in the clinical medicine.

• 대한간호학회지
• /
• 제51권3호
• /
• pp.294-304
• /
• 2021

Purpose: This study aimed to investigate objectively measured physical activity (PA) in institutionalized older adults with mild cognitive impairment (MCI) and to elucidate the influence of autonomic nervous function, salivary cortisol, and PA on cognitive functions based on neurovisceral integration model. Methods: Overall cognitive function was evaluated using the mini-mental state examination (MMSE) and executive function was evaluated using semantic verbal fluency test and clock drawing test. Actigraph for PA, HRV and sAA for autonomous function, and the geriatric depression scale for depression were used. Saliva specimens were collected in the morning for sAA and cortisol. Results: Ninety-eight older adults from four regional geriatric hospitals participated in the study. They took 4,499 steps per day on average. They spent 753.93 minutes and 23.12 minutes on average in sedentary and moderate-to-vigorous activity, respectively. In the multiple regression analysis, lower salivary cortisol level (β = - .33, p = .041) and greater step counts (β = .37, p = .029) significantly improved MMSE score. Greater step count (β = .27, p = .016) also exerted a significant influence on verbal fluency, and greater sAA (β= .35, p = .026) was significantly associated with a better clock drawing test result. Conclusion: Salivary cortisol, sAA and physical activity were significantly associated with cognitive functions. To prevent older adults from developing dementia, strategies are needed to increase their overall PA amount by decreasing sedentary time and to decrease salivary cortisol for cognitive function, and to maintain their sympathetic nervous activity for executive function.

• 대한정형도수물리치료학회지
• /
• 제1권1호
• /
• pp.9-14
• /
• 1995

인체에서 발생하는 체열을 과학적으로 이용하여 질병을 진단하고 치료과정을 관찰하고 예후를 추측할 수 있는 Thermography는 현대의학의 임상 여러분야에서 응용할 수 있는 유용한 진단장비에 속한다 하겠다. 인체의 피부온도는 좌우 대칭적으로 온도분포를 나타내며 여러가지 생리학적인 원인에 의하여 온도는 변화할 수 있으며, 그러한 온도변화는 여러 질병과의 연관성을 갖게 된다. Thermography는 유방암세포의 증식에 따른 유방체표면의 초기온도 상승을 screening 함으로서 조기에 유방암을 발견할 수 있으며, 척추의 신경근 자극에 따른 체열분포를 파악함으로서 신경근의 이상유무 및 척추질환을 진단할 수 있으며, 말초 혈액순환 장애 등으로 인한 질환에 있어서도 뚜렷한 체표면 온도분포를 나타내 줌으로서 혈액순환의 장애분포를 시각적으로 관찰할 수 있는 이점을 지니고 있다. 또한 정형 물리치료 분야에 속하는 근-골격계 질환에 있어서의 근육통, 압통점, 염좌, 염증질환 등을 구별할 수 있고 나아가 치료 전후에 적외선 체열검사를 실시해 봄으로서 치료전이나 치료결과에 대한 객관적인 평가를 할 수 있다는데 큰 의의가 있다고 하겠다.

• Annals of Clinical Neurophysiology
• /
• 제25권1호
• /
• pp.32-37
• /
• 2023

Background: Type 2 diabetic mellitus (T2DM) is an emerging global pandemic which is associated with lots of co-morbidities and reported vascular dysfunctions. T2DM associated vascular dysfunctions leads to vasculopathy in the form of altered peripheral vascular dynamics. Cold stress test (CST) is a reliable sympathetic reactivity test used for assessing vascular dysfunctions. In this study we are trying to quantify vascular dysfunctions in T2DM patients non invasively by various parameters of photoplethysmography (PPG) of cold stress test. Methods: Case control study had done in referral health center AIIMS, Raipur. Parameters are recorded by finger-PPG before, during and after CST (1 min) in 2 groups, control (n = 20 healthy volunteers) and case (n = 20 diagnosed T2DM patients). Results: Due to cold stress, PPG parameter peak amplitude was significantly decreased in both healthy and T2DM groups (p <0.001 and p <0.001, respectively). However, recovery trend of amplitude was significantly slow in T2DM compared to healthy subjects. Another PPG parameter peak to peak interval was significantly higher in healthy group compared to T2DM patients. Conclusions: This study showed that T2DM patients has significant deranged pulse volume parameters like amplitude and peak to peak interval can be used to objectively quantify the vasculopathy in T2DM patients by using sympathetic reactivity to cold stress.

• 한국응용과학기술학회지
• /
• 제35권2호
• /
• pp.445-453
• /
• 2018

본 연구는 일회성 호흡훈련 피드백이 중년여성의 HRV-자율신경시스템 변화에 미치는 영향을 분석고자 하였다. 연구대상자는 중년여성(40-60세) 총 24명을 호흡군 12명, 통제군 12명으로 무선할당하여 일회성 호흡 훈련을 실시하였다. 호흡군의 피드백 훈련은 총 15분 동안 실시되었으며, 10분 간 전문가 지도에 따른 호흡 자각 훈련 후 5분 간 자율호흡 훈련을 실시하였다. 자료의 분석은 SPSS WIN 20.0으로 반복측정 변량분석(Repeated Measures ANOVA)을 실시하였으며, 이를 통해 얻어진 결론은 다음과 같다. 중년여성들은 일회성 호흡 훈련 후 SDNN, RMSSD, LF, HF가 유의하게 높아졌으며, 호흡군이 통제군보다 SDNN, RMSSD, LF, HF이 유의하게 높아진 것으로 나타났고, Mean HR과 LF/HF는 집단과 시기의 주효과, 집단과 시기의 상호작용효과 모두 유의한 차이는 나타나지 않았다. 이상의 결과로 일회성 호흡훈련 피드백은 중년여성들의 SDNN, RMSSD, 교감활성, 부교감활성에 효과적이며, 이러한 호흡 훈련 프로그램은 자율신경계 균형 능력을 향상시켜 중년여성들의 스트레스 완화 및 자율신경실조증을 회복할 수 있는 운동중재의 효용 가치를 기대할 수 있다고 사료된다.

• Pediatric Infection and Vaccine
• /
• 제10권1호
• /
• pp.114-122
• /
• 2003

본 저자들은 상기도 감염 후 발열과 배뇨곤란, 하지의 근력저하를 주소로 내원한 7세 환아에서, 급성 횡단성 척수염 증상으로 시작하여 의식 변화와 호흡부전의 급성 파종성 뇌척수염으로 진행한 1례에서 enterovirus 71을 증명하고 고용량 methylprednisolone 정주 후 증상의 호전을 경험하였기에 문헌 고찰과 함께 보고하는 바이다.