• Title/Summary/Keyword: Automatic Radiopharmaceutical Synthesis System

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Development of A Validation System For Automatic Radiopharmaceutical Synthesis Process Using Network Modeling (방사성의약품 합성 프로세스 검증을 위한 네트워크 모델링)

  • Lee, Cheol-Soo;Heo, Eun-Young;Kim, Jong-Min;Kim, Dong-Soo
    • IE interfaces
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    • v.24 no.3
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    • pp.187-195
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    • 2011
  • The automatic radiopharmaceutical module consists of several 2-way valves, couple of syringes, gas supply unit, heating(cooling) unit and sensors to control the chemical reagents as well as to help the chemical reaction. In order to control the actuators of radiopharmaceutical module, the process is tabulated using spread sheet as like excel. Unlike the common program, a trivial error is too critical to allowed in the process because the error can lead to leak the radioactive reagent and to cause the synthesis equipment failure during synthesizing. Hence, the synthesis process has been validated using graphic simulation while the operator checks the whole process visually and undergoes trial and error. The verification of the synthesis process takes a long time and has a difficulty in finding the error. This study presents a methodology to verify the process algebraically while the radiopharmaceutical module is converted to the network model. The proposed method is validated using actual synthesis process.

Development of One-channel Gamma ray spectroscope for Automatic Radiopharmaceutical Synthesis System (방사성 의약품 자동합성장치용 단채널 감마선 분광기 보드의 설계 및 제작)

  • Song, Kwanhoon;Kim, Kwangsoo
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.4
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    • pp.193-200
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    • 2014
  • In this paper, the prototype of one-channel gamma-ray spectroscope for automatic radiopharmaceutical systhesis system was designed and characterized. The prototype employed CZT (CdZnTe) spear detector for gamma-ray detection and employed analog-type signal processing method. A radioactive sample Co-60 was used for measuring performance of the gamma-ray spectroscope and energy spectrum is gained with bandwidth of 1173keV. The analog board is made up of SF (shaping filter) and PHA (peak and hold amplifier) for shaping CZT output signal appropriately and ADC (analog to digital converter) and FPGA (field programmable gate array) for drawing gamma-ray spectrum by counting the digitalized gamma-ray signal data.