• 제목/요약/키워드: Autologous

검색결과 597건 처리시간 0.021초

Cystic Adventitial Disease of the Popliteal Artery: Resection and Repair with Autologous Vein Patch

  • Maeng, Young-Hee;Chang, Jee-Won;Kim, Sun-Hyung
    • Journal of Chest Surgery
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    • 제44권3호
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    • pp.266-268
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    • 2011
  • Cystic adventitial disease is rare, but it is one of the well-recognized causes of non-atherosclerotic arterial stenosis or obstruction. Despite one of its most common symptoms being chronic intermittent claudication, it may be misdiagnosed as arterial embolism when presented with acute ischemic symptoms. Surgical resection is recommended because of recurrence or a low success rate with aspiration or endovascular stent. We performed resection and repair with autologous vein patch for cystic adventitial disease of the popliteal artery of a 57-year-old man presenting with pain, pallor, and paresthesia, without any postoperative complications or recurrence.

농도분배에 따라 분리한 사람 적혈구 막에 관한 연구 (Studies of Density-Fractionated Human Ervthrocvte Membranes)

  • 정종문
    • 한국동물학회지
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    • 제37권4호
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    • pp.597-604
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    • 1994
  • Membranes obtained from the normal human RBC population were separated by continuous sucrose density gradient centrifugation and the density-fractionated membranes were then examined for changes in molecular markers. This study focuses on changes of (i) the membrane protein profile, (ii) differences in membrane-associsted enzyme activities, and (iii) the amount of autologous IgG bound. The following observations were made: (i) ratios for band 4. la over the sum of bands (4. la + 4.Ib) ranged from 0.58 to 0.79 for membranes of lowest density; (ii) significant changes in bound glyceraldehyde-3-phosphate dehydrogenase and acetvlcholinesterase activities were found; (iii) the amounts of autolosous IgG's attached to the red blood cells was highest in the membrane fraction of lowest density.

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선천성 대동맥판 협착증에서 폐동맥판 자가이식편을 이용한 대동맥판 교체술:동종판막을 쓰지 않는 Ross술식 (Aortic Valve Replacement with Pulmonary Autograft in Patient with Congenital Aortic Stenosis : Ross Procedure without Homograft -one case report -)

  • 이은상;윤태진;서동만
    • Journal of Chest Surgery
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    • 제32권3호
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    • pp.303-306
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    • 1999
  • 본 증례는 Ross 술식에서 동종판막이나 이종판막을 쓰지않고 자가 대동맥 조직과 심낭으로 우심실 유출로를 성공적으로 재건한 보고이다. 선천성 대동맥판막 협착증을 진단 받은 8세 환아에서 시행한 폐동맥 자가 이식편을 이용하여 대동맥판을 교체하고 자가 대동맥 조직과 심낭편으로 단엽 판막을 만들어 우심실 유출로를 재건하였다. 술후 검사에서 심실과 새로운 대동맥판의 기능이 좋아 투약없이 19개월째 외래 추적관찰 중이다.

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성문하 확장과 단단문합술을 동시에 이용한 기관 및 성문하 협착증 치험 2례 (Treatment of Laryngotracheal Stenosis: Combined Cricoid Augmentation by Autologous Cartilage and Laryngotracheal Anastomosis)

  • 정동학;김병훈;조정일;김영진
    • 대한기관식도과학회지
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    • 제3권1호
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    • pp.148-153
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    • 1997
  • Laryngotracheal stenosis is one of the most troublesome diseases in the Em field. Subglottic stenosis can be treated by a cricoid augmentation with rib cartilage. In case of tracheal stenosis, the treatment of choice is by tracheal end-to-end anastomosis after resection of the stenotic site. However, in case of subglottic stenosis combined with tracheal stenosis, it is hard to manage. Even though several methods(such as thyrotracheal anastomosis) have been tried, they have some limitations too much excision of normal trachea and too much pulling up of the trachea after resection of the stenotic lesion. The authors have managed two cases of laryngotracheal stenosis as an anterior and posterior subglottic augmentation with an autologous cartilage graft and laryngotracheal anastomosis. The first few weeks after the operation, we could do a decannulation successfully, but in one case the patient developed restenosis. Even though one case was unsuccessful, the authors believe that this method could be used in the treatment of laryngotracheal stenosis.

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Therapeutic Effect of Autologous Activated Platelet-rich Plasma Therapy on Mid-dermal to Full-thickness Burns: A Case Series

  • Karina, Karina;Ekaputri, Krista;Biben, Johannes Albert;Hadi, Pritha;Andrew, Hubert;Sadikin, Patricia Marcellina
    • Archives of Plastic Surgery
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    • 제49권3호
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    • pp.405-412
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    • 2022
  • Although modern medicine has made great strides in the management of burn injuries, associated complications such as pain, infection, dyspigmentation, and scarring have yet to be fully dealt with. Although skin grafting and meshing are routinely performed on burn patients, this method poses a risk for adverse effects. Activated autologous platelet-rich plasma (aaPRP), which is increasingly used in the field of plastic surgery, contains growth factors beneficial for wound regeneration. Seven cases of burns with varying severity and conditions that were treated with intralesional subcutaneous injection and intravenous aaPRP are presented and discussed herein. This case series indicates that subcutaneous and intravenous aaPRP is a safe procedure with the potential to be an alternative when skin grafting cannot be done or as an adjunct treatment to skin grafting.

조직공학적 인조혈관의 생체 내 이식 실험 (In Vivo Experiment of Tissue-Engineered Artificial Vessel)

  • 임상현;조승우;홍유선;김병수;유경종;장병철;최차용
    • Journal of Chest Surgery
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    • 제37권3호
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    • pp.220-227
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    • 2004
  • 관상동맥 질환과 말초혈관 질환의 증가에 따라 직경 6 mm 이하의 소구경 혈관의 필요성이 증가하고 있다. 저자들은 조직공학적 방법을 이용하여 소구경 인공혈관을 제작하여 생체 실험을 시행하였다. 동종 판막을 얻어 이를 탈세포화시킨 후 피실험동물의 골수를 채취하여 탈세포화시킨 혈관용 지지체(scaffold) 위에 이식하였다. 이와 같이 하여 제작된 인공 혈관을 잡견의 양측 경동맥에 이식한 후 혈관이 막히거나, 8주가 되었을 때 이를 제거하여 조직학적 검사를 시행하였다. 자가 세포를 이식하지 않고 지지체만을 이식하였던 대조군 4마리 중 3마리의 혈관은 2주 이내에 모두 막힌 것을 확인하였고 나머지 한 마리의 혈관은 혈관류(aneurysm)가 발생하였다. 그러나 자가 세포를 이식한 실험군 4마리 중 2마리는 각각 4주와 6주까지 혈관의 개통성을 유지하였고, 나머지 2마리는 8주까지 혈관의 개통성을 유지하였다. 조직학적 검사 결과, 8주까지 개통성을 유지하였던 혈관은 정상의 혈관과 거의 유사한 조직학적 구조를 나타내었다. 자가 세포와 탈세포화된 지지체를 이용하여 제작한 인공혈관은 조직학적 검사 결과 정상과 유사한 구조로 재생이 가능함을 보여주었다.

구순구개열 환자에서의 이종골 이식재를 통한 견치의 맹출 (CANINE ERUPTION THROUGH BIO-$OSS^{(R)}$ GRAFT IN PATIENTS WITH CLEFT LIP & PALATE)

  • 김지훈;최병호;장채리
    • 대한장애인치과학회지
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    • 제6권2호
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    • pp.105-111
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    • 2010
  • 이종골의 치아맹출에 대한 기존 문헌 및 동물실험 연구를 바탕으로, 자가골 및 동종골 이식이 어려운 구순구개열 환자에서 이종골(Bio-$Oss^{(R)}$)을 이식하여 성공적으로 매복된치아의 맹출을 유도하였고, 치근의 형성 및 치아의 골내 이동도 정상적으로 이루어졌다.

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Safety of long-term subcutaneous free flap skin banking after skin-sparing mastectomy

  • Verstappen, Ralph;Djedovic, Gabriel;Morandi, Evi Maria;Heiser, Dietmar;Rieger, Ulrich Michael;Bauer, Thomas
    • Archives of Plastic Surgery
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    • 제45권2호
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    • pp.146-151
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    • 2018
  • Background A persistent problem in autologous breast reconstruction in skin-sparing mastectomies is skin restoration after skin necrosis or secondary oncological resection. As a solution to facilitate reconstruction, skin banking of free-flap skin has been proposed in cases where the overlying skin envelope must be resected, as this technique spares the patient an additional donor site. Herein, we present the largest series to date in which this method was used. We investigated its safety and the possibility of skin banking for prolonged periods of time. Methods All skin-sparing mastectomies and immediate autologous breast reconstructions from December 2009 until June 2013 at our institution were analysed. Results We identified 31 patients who underwent 33 free flap reconstructions in which skin banking was performed. Our median skin banking period was 7 days, with a maximum duration of 171 days. In 22.5% of cases, the banked skin was used to reconstruct overlying skin defects, and in 9.6% of cases to reconstruct the nipple-areolar complex. Microbiological and histological investigations of the banked skin revealed neither clinical infections nor malignancies. Conclusions In situ skin banking, even for prolonged periods of time, is a safe and cost-effective method to ensure that skin defects due to necrosis or secondary oncological resection can be easily reconstructed.

Autologous Fat Graft in the Reconstructed Breast: Fat Absorption Rate and Safety based on Sonographic Identification

  • Kim, Hong Youl;Jung, Bok Ki;Lew, Dae Hyun;Lee, Dong Won
    • Archives of Plastic Surgery
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    • 제41권6호
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    • pp.740-747
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    • 2014
  • Background Autologous fat graft has become a useful technique for correction of acquired contour deformity in reconstructed breasts. However, there remains controversial regarding the efficacy and safety of the practice for reconstructive breast surgery. Methods A retrospective review was performed on 102 patients who had secondary fat grafting after breast reconstruction. Fat harvest, refinement and injection were done by Coleman's technique. All patients were followed up postoperatively within 1 month and after 6 months including physical examination and ultrasonography. In 38 patients, the reabsorption rate was calculated by serial changes of thickness between skin and pectoral fascia in the ultrasonic finding. Locoregional recurrence rate was compared with control group of 449 patients who had breast reconstruction without fat graft in the same time period. Results Average 49.3 mL fat was injected into each breast. The most common location of fat graft was upper pole, followed by axilla, lower and medial breasts. During 28.7 months of average follow-up period, 2.9% of total patients had symptoms of palpable mass on fat graft side and ultrasonography identified fat necrosis and cyst formation in 17.6% of the patients. Calculated fat reabsorption rate was 32.9%. Locoregional recurrence was occurred in 1 patient (0.9%) and the rate was not different significantly with control group (2%). Conclusions Although further studies are required to provide surgeons with definitive guidelines for the implementation of fat grafting, we propose autologous fat graft is an efficient and safe technique for secondary breast reconstruction.

악교정 수술후 혈액학적 변화에 대한 연구 (A HEMATOLOGIC STUDY OF ORTHOGNATHIC SURGERY PATIENTS)

  • 이종석;고승오;정길중;임대호;백진아;신효근
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제29권2호
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    • pp.157-166
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    • 2007
  • Moderns have desire likely to be further good-looking concomitant with a qulitative advancement of the life. Orthognathic surgery for the correction of dentofacial deformities is a common elective procedure. It's possible to occur many complication during the operations and especially, an excessive bleeding of those may be fatal and so a tranfusion is performing for the prevention and management of that. The most notable of these for reduction of blood loss is the utilization of induced hypotensive anesthetic technique to reduce the mean arterial pressure between 55 and 60 mmHb. Another method for dealing with blood loss following orthognathic surgery is the transfusion of blood obtained as an autologous tranfusion or from banked blood. Some of the disadvantage of banked blood are overcome with the use of predeposited autologous transfusion. But currently, surgeons try so that even autologous transfusion may not transfuse the patients. We made a comparative study of hematologic change and transfusion requirement based on a series of 200 patients who had an orthognathic surgical procedure at Chonbuk National University during the period 2001-2005. This study is to make a comparative analysis of an post-operative hematologic (Hemoglobin, Hematocrit, Red blood cell) change and duration of the procedure under induced hypotensive anesthesia in healthy orthognathic patients.