• Title/Summary/Keyword: Attention Deficit Disorder with Hyperactivity

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A Brief Replication Study Comparing Stimulants and Non-Stimulants for Attention-Deficit/Hyperactivity Disorder Treatment with a Focus on the Compliance, Efficacy, and Satisfaction

  • Roh, Hyosung;Kim, Bongseog
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.32 no.1
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    • pp.10-16
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    • 2021
  • Objectives: The aim of this study was to compare the compliance, efficacy, and satisfaction associated with methylphenidate and atomoxetine for treating attention-deficit/hyperactivity disorder (ADHD). Methods: The subjects were 44 patients who met the Diagnostic and Statistical Manual of Mental Disorder-5 diagnostic criteria for ADHD and were treated with methylphenidate or atomoxetine. The methylphenidate formulations included immediate release (IR), extended release (ER), and osmotic-controlled release oral delivery system (OROS). Patients and parents reported the average number of days per week the medication was taken. Efficacy was assessed using the ADHD Rating Scale. Satisfaction with medication scale (SAMS)-parent report form and SAMS-self-report form were used to evaluate parents' and patients' satisfaction, respectively. Results: Patients and parents were more satisfied with methylphenidate than with atomoxetine. There were no significant differences in the compliance with and efficacy of methylphenidate and atomoxetine. Compliance with methylphenidate IR and ER was markedly lower than that with OROS methylphenidate or atomoxetine. Conclusion: Methylphenidate OROS formulation can be considered a suitable option given its high rates of compliance, satisfaction, and efficacy.

Meta Analysis of Variables Related to Attention Deficit Hyperactivity Disorder in School-Age Children (학령기 ADHD 아동의 주증상과 관련변인에 관한 메타분석)

  • Park, Wan-Ju;Seo, Ji-Yeong;Kim, Mi-Ye
    • Journal of Korean Academy of Nursing
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    • v.41 no.2
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    • pp.256-268
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    • 2011
  • Purpose: The purpose of this study was to use meta-analysis to examine recent domestic articles related to attention deficit hyperactivity disorder (ADHD) in school-age children. Methods: After reviewing 213 articles published between 1990 and 2009 from and cited in RISS, KISS, and DBpia, the researchers identified 24 studies with 440 research variables that had appropriate data for methodological study. SPSS 17.0 program was used. The outcome variables were divided into five types: Inattention, hyperactive impulsive, intrinsic, extrinsic, and academic ability variables. Results: Effects size of overall core symptoms was 0.47 which is moderate level in terms of Cohen criteria and effects size of overall negative variables related ADHD was 0.27 which is small level. The most dominant variable related to ADHD was obtained from hyperactive-impulsive (0.70). Also academic ability (0.45), inattention (0.37), and intrinsic variables (0.29) had a small effect whereas extrinsic variables (0.13) had little effect on descriptive ADHD study. Conclusion: The results reveal that ADHD core symptoms have moderate effect size and peripheral negative variables related ADHD have small effect size. To improve the reliability of the meta-analysis results by minimizing publication bias, more intervention studies using appropriate study designs should be done.

A study on the relationship between attention deficit hyperactivity disorder, college adjustment, major satisfaction, and academic motivation in college students (대학생의 ADHD성향과 대학적응, 전공만족 및 학습동기의 관련성 연구)

  • Song, Kwui-Sook;Lee, Su-Jung
    • Journal of Korean society of Dental Hygiene
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    • v.21 no.3
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    • pp.311-318
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    • 2021
  • Objectives: The purpose of this study was to understand the level and patterns of college adjustment, major satisfaction, academic engagement, and attention deficit hyperactivity disorder (ADHD). This study examined the factors influencing adaptation to college life. Methods: This study was approved by the institutional review board of 00 university. We analyzed 166 survey data responses collected by distributing questionnaires from June 1 to July 2, 2020. Statistical product and service solutions version 23.0 was used for statistical analyses. The data were presented as frequencies and percentages or means and standard deviations, and pearson correlation analysis and multiple regression analysis were performed. Results: There was a significant difference in the average score of major satisfaction according to the type of college (university) and grades. For college adjustment, there was a significant difference in the average score according to major grades. Academic engagement showed a significant difference in the average score according to the college type and grade. Major satisfaction, college adjustment, and academic motivation showed significant positive correlations among the variables, whereas ADHD, major satisfaction, and college adjustment showed a significant negative correlation. Multiple regression analysis revealed that major satisfaction (p<0.001) and academic motivation (p<0.001) were factors affecting college adjustment (p<0.05). Conclusions: It is necessary to develop and apply specific and systematic adaptation programs to improve the understanding, control, and guidance methods for college students and to promote human relations, such as school life and social life.

Convergence Approach to the Incidence of Visual Function Problems by the Type of ADHD in Children (ADHD 아동의 유형별 시각 기능의 문제 발생률에 대한 융복합적 접근)

  • Cho, Hyung-Chel;Ro, Hyo-Lyun
    • Journal of the Korea Convergence Society
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    • v.12 no.2
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    • pp.113-120
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    • 2021
  • The objective of this study is to identify the visual function impairment of children with each type of attention deficit hyperactivity disorder(ADHD). The subjects of this study were 49 children diagnosed with ADHD with visual function out of the normal range. The type of ADHD was investigated using the Korean-ADHD Rating Scale and visual function test. The attention deficit type(69.4%) of ADHD was the most common type among children with ADHD with vision problems. Although their overall naked-eye visual acuity was good, about 50% of the subjects showed problems with visual function. For those with the attention deficit type of ADHD, the myopia-related refractive error was high. For those with the hyperactivity type of ADHD, the astigmatism-related refractive error was higher. For those with vergence function disorder, convergence insufficiency was the most common. As there were differences in the visual impairment characteristics of children with different types of ADHD, it is necessary to approach a child's problem behavior through examination and screening for visual function disorders.

ASSESSMENT OF CHILDREN WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER (주의력결핍과잉활동 장애의 평가)

  • Oh, Kyung-Ja
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.1 no.1
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    • pp.65-76
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    • 1990
  • Behavioral characteristics of Attention Deficit Hyperactivity Disorder (ADHD) are aften observed in normal children. As a result, it is at times difficult to distinguish behavior disorder of clinical significance and normal developmental phenomenon. In addition, symptoms of ADHD can vary greatly depending on situations and social context, creating considerable difficulties in assessment. Therefore it is important to obtain information from various sources and in diverse situations. It is also desirable to quantify the severity of the problems whenever possible and determine their clinical significance by comparing the data to developmental norms. Specifically, various assessment methods such as interview with parent and child, behavior rating scales, behavioral observation and psychological testing were reviewed with discussion on merits and limitatious of each. It was emphasized that systematic and comprehensive assessment utilizing appropriate methods is necessary for accurate diagnosis and treatment evaluation of ADHD.

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Determining a BMDL of Blood Lead Based on ADHD Scores Using a Semi-Parametric Regression

  • Kim, Ah-Hyoun;Ha, Min-A;Kim, Byung-Soo
    • The Korean Journal of Applied Statistics
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    • v.25 no.3
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    • pp.389-401
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    • 2012
  • This paper derives a benchmark dose(BMD) and its 95% lower confidence limit(BMDL) using a semi-parametric regression model for small lead based changes in attention-deficit hyperactivity disorder(ADHD) scores in the first wave of the Children's Health and Environment Research(CHEER) survey data, which have been regularly collected in South Korea since 2005. Ha et al. (2009) showed that the appearance of ADHD symptoms had a borderline trend of increasing with the blood lead concentration. Butdz-J${\o}$rgensen (EFSA, 2010a) derived the BMDL of lead corresponding to a benchmark region of 1 full intelligent quotient (IQ) score using the raw data in Lanphear et al. (2005, EHP). European Food Safety Authority (EFSA, 2010b) determined the BMDL of $1.2{\mu}g/dl$ as a reference point for the characterization of lead when assessing the risk of the intellectual deficit measured by IQ scores. Kim et al. (2011) indicated that an even lower BMDL could be obtained based on the ADHD score; however, the BMDLs depended heavily upon the model assumptions. We show in this paper that a semi-parametric approach resolves the model dependence of BMDLs.

An Open-Label Study of OROS-Methylphenidate for Neuropsychological Changes in Children and Adolescents with Attention-Deficit Hyperactivity Disorder (주의력 결핍 과잉 행동 환자에서 OROS-Methylphenidate 투여 후 신경심리학적 변화에 대한 개방 연구)

  • Kook, So-Dahm;Kim, Joo-Young;Cheon, Keun-Ah;Jhung, Kyungun;Song, Dong-Ho
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.24 no.3
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    • pp.157-163
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    • 2013
  • Objectives : Previous studies reported that attention-deficit hyperactivity disorder (ADHD) resulted from a deficit of selective attention and sustained attention. In this study, we assessed the result of methylphenidate-induced changes of the cerebral frontal executive functions in patients with ADHD. Methods : The subjects in this study consisted of 16 ADHD patients whose age ranged from 7 to 12. We used ADHD Diagnostic System (ADS) for the attention improvement, and the Stroop Test for the executive function response to pharmacotherapy with MPH. Results : After pharmacotherapy with methylphenidate for 12 weeks, the study group showed improvement in the clinical aspects through Clinical Global Impression-Severity, ADHD-rating scale and Inattention/Overactivity With Aggression Conner's Parents Rating Scale. In the ADS test, only in auditory task there was a decrease of both the response time and the standard deviation of the response time significantly. In the Stroop Test, there was a decrease in the word task, color task and color-word task significantly. Conclusion : Our results show that psychostimulant medication improves neuropsychological function, including the cerebral frontal executive function. This study implies that we have to consider the improvement of executive function, as well as attention when evaluating the efficacy of treatment.

Clinical and Neuropsychological Characteristics of Adult Alcohol Use Disorder Patients with or without Attention-Deficit Hyperactivity Symptom (성인 알코올사용장애 환자에서 주의력결핍 과잉행동 증상 유무에 따른 임상적 및 신경심리학적 특성)

  • Jo, Jung Min;Lee, Dong Jun;Jung, Kyung Hi;Oh, Song In;Ahn, Dong Hyun
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.25 no.4
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    • pp.209-216
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    • 2014
  • Objectives : Alcohol use disorder (AUD) is often comorbid with adult attention-deficit hyperactivity disorder (ADHD) and other psychiatric illnesses. When associated with other mental problems, the prognosis of the AUD can be more serious. This study shows research on the clinical and neuropsychological characteristics according to whether or not ADHD symptoms and AUD were comorbid. Methods : A total of 64 adult inpatients who completed AUD scales about adult ADHD, alcohol dependence, depression, anxiety, and impulsiveness. They also completed neuropsychological tests about attention and executive function. According to the Adult ADHD Self-Report Scale score, patients were categorized into two groups (ADHD symptom positive/negative group). Results : Fourteen among the 64 subjects were part of the ADHD symptom positive group (21.9%). They had statistically significant shorter abstinence periods and a higher rate of history of 'rule violation during school' and 'physical damage in childhood' compared to the ADHD symptom negative group. Conclusion : The comorbidity rate with ADHD symptom in adult AUD is higher than the general population. The ADHD symptom positive group suffered from more severe and refractory AUD. Considering the more frequent history of rule violation during school in the ADHD symptom positive group, the association between ADHD and AUD may be mediated by conduct disorder. Therefore we suggest the necessity of careful evaluation and intervention in children and adolescents with ADHD and conduct disorder.

Classification and Family Characteristics of Attention-Deficit Hyperactivity Disorder Children (주의력결핍-과잉행동 아동의 범주화와 가족환경 특성)

  • Wun, Jung-Ja;Kim, Yeong-Hee
    • Journal of the Korean Home Economics Association
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    • v.36 no.8
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    • pp.123-140
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    • 1998
  • The purpose of this study was to verify preschool children can be classified of Attention-Deficit Hyperactivity Disorder (ADHD) children across situation. It also was to examine differences among groups according to sex and age, and to investigate the family caracterisitcs of ADHD groups. The subjects of this study consisted of 228 preschool chilren (147 boys and 136 girls aged from 3- to 7- year-old) drawn from five Child Care Centers in Chung-Ju. Data were analyzed by the frequency, percentages, Cronbach's ${\alpha}$ coefficient, ${\chi}^2$-test, F-test, Tukey post-hoc test, and Pearson correlation using SAS program. The results were as follows: 1. Preschool children could be classified by four diagnostic groups across situation; (1) 168 children (59%) of the control group (no disorder of ADHD), (2) 49 children (17%) of ADHD-Home group (ADHD only at home), (3) 43 children (15%) of ADHD-School group (ADHD only at school), and (4) 23 children (8%) of ADHD-PH group (ADHD both at home and at school). Ratings by parents and by teachers correlated very low with each other, as in previous studies. These results confirm the findings that ADHD be classified across situation. 2. There were significant differences among four groups according to sex and age. In the ADHD-PH groups, the boys is 3 times higher than the girls and the children aged 6- to 7-year-old was shown highly distributed in the pervasive ADHD.

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The Comorbidity of Attention Deficit Hyperactivity Disorder and the Effect of Methylphenidate on it (주의력 결핍 과잉 운동 장애 환자들의 약물치료 효과 및 Comorbidity에 관한 연구)

  • Lee, Jong-Bum;Park, Hyung-Bae
    • Journal of Yeungnam Medical Science
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    • v.10 no.1
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    • pp.166-178
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    • 1993
  • The objectives of this study were to evaluate the effect of methylphenidate on attention deficit hyperactivity disorder (ADHD) and the comorbidity of the disorder, using child attention problem checklist to 56 (male: 38, female: 18) patients from, March 992 to February 1993. The results were as follows: Among 56 subjects, ADHD alone were 20 (335.71%) subjects, and with one additional diagnosis were 31 (55.35%) subjects and with two additional diagnosis were 5 (8.93%) subjects. There was significant improvement on symptoms in the scores rated by teachers in 7th and 28th day after menthlphenidate administration compared to baseline score (P<0.05) and 28th day score showed significant improvement compared to 7th day score (P<0.05) and 28th day score showed significant improvement compared to 7th day score (P<0.05). There was significant improvement on symptoms in the scores rated by parents in 28th day after methylphenidate administration improvement compared with 7th day score. In single administration of methylphenidate in Sunday morning score compared to afternoon score (P<0.05). In the administration of significant improvement on symptoms compared with the Sunday morning rating score of parents (P<0.05) and the 28th day comparison was also showed significant improvement on symptoms in the scores rated by teachers compared with the scores rated by parents on symptoms (P<0.05). Among group comparison, all groups showed significant improvements (P<0.05) except conduct disorder & oppositional defiant group.

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