• Journal of the Society of Naval Architects of Korea
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• v.46 no.6
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• pp.587-594
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• 2009

In the paper the effect of a stern-plate attached to a ship was taken into account. The relationship between the trim angle of a ship and the wave-resistance coefficient induced by the a stern-plate was studied using the potential flow analysis method. Numerical algorithm was described using the panel method and the vortex lattice method(VLM) to simulate the flow phenomena around a ship. The non-linearity of the free surface boundary conditions were considered using the iterative method and the IGE-GMRES(Incomplete Gaussian Elimination-The Generalized Minimal RESidual) algorithm was adopted to solve the linear equation at each iterative step. Numerical calculations were carried out to investigate the validity of the adopted algorithm using KCS(KRISO 3600 TEU Container) hull. Possible cases for attachment of the plate were checked. The results showed that the numerical algorithm could be physically appropriate.

• Journal of Veterinary Science
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• v.22 no.3
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• pp.25.1-25.16
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• 2021

Background: Malignant lymphoma is the most common hematopoietic malignancy in dogs, and relapse is frequently seen despite aggressive initial treatment. In order for the treatment of these recurrent lymphomas in dogs to be effective, it is important to choose a personalized and sensitive anticancer agent. To provide a reliable tool for drug development and for personalized cancer therapy, it is critical to maintain key characteristics of the original tumor. Objectives: In this study, we established a model of hybrid tumor/stromal spheroids and investigated the association between canine lymphoma cell line (GL-1) and canine lymph node (LN)-derived stromal cells (SCs). Methods: A hybrid spheroid model consisting of GL-1 cells and LN-derived SC was created using ultra low attachment plate. The relationship between SCs and tumor cells (TCs) was investigated using a coculture system. Results: TCs cocultured with SCs were found to have significantly upregulated multidrug resistance genes, such as P-qp, MRP1, and BCRP, compared with TC monocultures. Additionally, it was revealed that coculture with SCs reduced doxorubicin-induced apoptosis and G2/M cell cycle arrest of GL-1 cells. Conclusions: SCs upregulated multidrug resistance genes in TCs and influenced apoptosis and the cell cycle of TCs in the presence of anticancer drugs. This study revealed that understanding the interaction between the tumor microenvironment and TCs is essential in designing experimental approaches to personalized medicine and to predict the effect of drugs.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.4
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• pp.296-308
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• 2021

Electroencephalography (EEG) provides the most accurate and quickest diagnosis of epilepsy. It is also an important examination for the real-time evaluation of brain function and seizures, no matter where. In the field of epilepsy, it is appropriate for a clinical pathologist with considerable knowledge of EEG and clinical experience to perform the role of a Physician Assistant (PA). The electrode attachment method is based on the international 10-20 system. The EEG reading is mainly taken by longitudinal bipolar montage. However, a reading using only one montage may result in an error. Hence, two or more montages should be used for readings according to the clinical situation. In the EEG, electric potentials are seen as contour lines. The most important principle in EEG reading is under-reading, not over-reading. The higher the repetitions of the EEG recording, the greater the sensitivity of the reading. For a good reading, the EEG recording must be of good quality. So, the relationship between the neurologist and the EEG technician is very important. In the future, it is expected that the field of activities of the EEG technician with abundant EEG reading experience and clinical practical knowledge will be further expanded.

• Journal of the Korea Convergence Society
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• v.10 no.1
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• pp.299-305
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• 2019

The purpose of study was to investigate the effects of career decision efficacy, learning Flow, and academic achievement on department adaptation of dental hygiene students. The subjects of the study are self-administered surveys of 200 students who indicated their intention to participate. 181 questionnaires were analyzed using SPSS 18.0. The results of this study show that career decision efficacy, learning flow, academic achievement affect to major satisfaction, major confidences, major attachment. The results of this study show that career decision efficacy, academic achievement affect to major vision. Some dental hygienists students need support systems such as learning methods and educational environment that can improve academic achievement and learning commitment in order to help students adapt to their department. In addition, education and career support for career decision efficacy should be continuously maintained.

• Journal of Periodontal and Implant Science
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• v.49 no.2
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• pp.105-113
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• 2019

Purpose: An unresolved inflammatory state contributes to the pathogenesis of periodontal disease and metabolic syndrome (MetS). Therefore, the purpose of this study was to evaluate the role of lipoxin A4 (LXA4), a proresolving lipid mediator, in the association between periodontal disease and MetS. Methods: Sixty-seven patients with MetS and 65 patients without MetS were included in the study. Sociodemographic information was obtained via a questionnaire, and detailed medical diagnoses were made. Periodontal parameters (plaque index [PI], gingival index [GI], probing pocket depth [PD], and clinical attachment level [CAL]) and metabolic parameters were measured, and serum LXA4 levels were determined. The associations among MetS, periodontal parameters, and serum LX levels were evaluated by adjusted multivariate linear regression analyses. Results: Patients with MetS were older and had a higher body mass index than patients without MetS. Periodontal parameters (PI, GI, PD, and CAL) were higher in patients with MetS than in those without MetS. Serum LXA4 levels were higher in patients without MetS. Multivariate linear regression analysis indicated a positive association between MetS and periodontal parameters (PD and CAL). Negative associations were established between MetS and LXA4 levels, and between LXA4 and periodontal parameters (PI, PD, and CAL). Conclusions: The presence of higher values of periodontal parameters in patients with MetS and the negative relationship of LXA4 with MetS and periodontal disease may support the protective role of proresolving lipid mediators in the association between periodontal disease and MetS.

• Journal of Species Research
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• v.11 no.4
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• pp.266-277
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• 2022

The current surveys of Ulva in the subtidal area around Jeju Island give a chance to discover unrecorded green algal species of the Korean macroalgal flora. As a result of this investigation, we found Ulva adhaerens Matusmoto & Shimada, inhabiting the subtidal regions, up to 15 m deep, and conducted the DNA barcoding on plastid rbcL-3P and tufA regions with describing the morphological characteristics. Our specimens of U. adhaerens forms a monophyletic clade with the Japanese type specimen and U. piritoka Ngāti Kuri, Heesch & W.A. Nelson from New Zealand exhibiting each 0.3% sequence divergences, respectively, in the plastid rbcL-3P. The genetic variation of U. adhaerens clade is 1.0-3.9% in rbcL-3P and 4.8-9.8% in tufA to each Ulva species, including the generic type, U. lactuca Linneaus. The morphology of Korean U. adhaerens specimens is identical to the type specimens of U. adhaerens from Japan having the development of rhizoidal filaments from both of the cell layers of the distromatic blade and the extension of rhizoidal clumps with adhesive trait between blades by extended rhizoidal clumps at the basal blades. The thallus attachment to substrate is by numerous minute discoidal plates made up of rhizoids originating from the inner part of distromatic blades in basal. Although there are still some problems to resolve the relationship between U. adhaerens and U. piritoka in the rbcL dataset and the phylogenetic pattern of the Group II intron of rbcL, we propose the new record of U. adhaerens in Korean macroalgal flora based on the morphological characteristics of Korean specimens. Continued study of the genus Ulva by morphological and molecular assessment will delimit the species of Ulva, elucidate the relationships between them, and uncover the species diversity.

• The Journal of the Convergence on Culture Technology
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• v.8 no.6
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• pp.243-250
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• 2022

This study attempted to explore the essential meaning of emotional experiences of bereavement of with the mother, the main caregiver of adult women. For this purpose, three adult women who had experienced bereavement with their mother were subjected to an in-depth interview method about their life experiences and their meanings. The collected data were analyzed by applying Colaizzi Phenomenological research method. As a method of deriving the research results, four categories of "Bereavement Experience," "Emotional Experience," "Relationship Experience," "Growth Experience," were derived by conducting a study on the essence of the emotional experience experienced by an adult women who loss her mother and the effect on the life of herself and her family became. This study is meaningful in that it contributed to recovery and growth by healing with positive life changes according to the passage of time and the will to overcome despite the trauma of suffering and loss due to the death of the mother, the attachment target.

• The Journal of the Convergence on Culture Technology
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• v.8 no.5
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• pp.341-349
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• 2022

This study explored in-depth emotional experiences influenced by childhood trauma of adult female survivors. For this purpose, in-depth interviews were conducted with married adult women who experienced trauma in their childhood. The collected data were analyzed using Colaizzi phenomenological research method. As a result of the study, 7 categories were derived: 'children who cannot protect themselves', 'childhood trauma,' 'insecure attachment and good child syndrome,' 'difficulties in interpersonal relationships,' 'difficulties in raising children,' 'somatization symptoms,' 'finding myself who is lost.' In addition, this study aims to understand the psychological experience of children in the family and the relationship between parents and children and the growth experience of healing them by comparing and contrasting the two cases of trauma. The foundation for healthy ego-resilience and emotional well-being has been laid through the research results on negative and maladaptive emotional experiences reflected throughout the life of adult women who suffered childhood trauma.

• Korean Journal of Social Welfare Studies
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• v.41 no.3
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• pp.81-106
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• 2010

The purpose of this study was to find out correlation and predictors of recovery predictive factors for North Korean refugees experienced torture in South Korea. This survey was conducted on 205 North Korean refugees with questions on socio-demographic variables, mental health & personality variables, and social & economical variables. The influence of these variables was analysed. Result indicated that sex, age, disease, child living in the North, marriage experience in the North and the China were associated with post-traumatic stress of torture. Also, depression, rumination, self-efficacy, resilience, secure-attachment, social support from the South, economic difficulties predicted the recovery for North Korean refugees with torture experience. Finally, clinical intervention with healing relationship and human rights for North Korean refugees were discussed.

• Parasites, Hosts and Diseases
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• v.61 no.1
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• pp.2-14
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• 2023

Trichomonas vaginalis is a flagellated protozoan that causes trichomoniasis, a common nonviral sexually transmitted infection. T. vaginalis infection is asymptomatic in most infected men but can lead to chronic infection. The inflammatory response to chronic T. vaginalis infection may contribute to prostatic diseases, such as prostatitis and benign prostatic hyperplasia (BPH); however, studies on the relationship between T. vaginalis infection and prostate diseases are scarce. In this review, we discuss evidence from our studies on the involvement of T. vaginalis in the pathogenesis of prostate diseases, such as prostatitis and BPH. Studies of prostatitis have demonstrated that the attachment of T. vaginalis trophozoite to prostate epithelial cells (PECs) induces inflammatory cytokine production and inflammatory cell migration, leading to prostatitis. T. vaginalis also causes pathological changes, such as inflammatory cell infiltration, acinar changes, interstitial fibrosis, and mast cell infiltration, in prostate tissues of infected rats. Thus, T. vaginalis is considered an infectious agent that triggers prostatitis. Meanwhile, studies of prostatic hyperplasia revealed that mast cells activated by T. vaginalis-infected prostate cells secreted inflammatory mediators, such as β-hexosaminidase and tryptase, which promoted proliferation of prostate stromal cell (PSC). Moreover, interleukin-6 produced by proliferating PSCs induced the multiplication of BPH-1 epithelial cells as a result of stromal-epithelial interaction, suggesting that the proliferation of T. vaginalis-infected prostate cells can be induced through crosstalk with mast cells. These collective findings suggest that T. vaginalis contributes to the progression of prostatitis and prostatic hyperplasia by creating an inflammatory microenvironment involving PECs and PSCs.