• 대한예방한의학회지
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• 제25권3호
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• pp.15-24
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• 2021

Objectives : This study sought to identify the Korean medicine treatment satisfaction of 3,000 patients who are 19 or older with experiences of being treated with Korean medicine at Korean medicine clinics or Korean medicine hospitals after experiencing traffic accidents. Methods : Frequency analysis was carried out to identify the effectiveness and satisfaction of Korean medicine services, and independent sample t-test was carried out to compare the satisfaction of users with different characteristics. Lastly, cross analysis(chi-square) was carried out to examine the relation between satisfaction and willingness to recommend. Results : Firstly, 91.3% of the patients were satisfied with the medical services provided at Korean medicine clinics, with the most satisfactory Korean medicine treatments in the order of acupuncture, moxibustion, cupping, Korean physical therapy, herbal acupuncture, Chuna manual therapy, herbal medicine, and others. Secondly, 71.3% of the patients answered that outpatient treatment was appropriate while 65.3% of the patients answered that hospitalized treatment was appropriate regarding duration of treatment at Korean medicine clinics, mostly being satisfied with the treatment duration at Korean medicine clinics and Korean medicine hospitals. Thirdly, in a survey on effectiveness of Korean medicine treatment compared to occidental medicine treatment, 85.9% of the patients answered: "the effectiveness of Korean medicine treatment is higher compared to occidental medicine or similar". Conclusion : From the results of this study, it was identified that satisfaction of Korean medicine treatment is high in motor insurance, and that higher satisfaction led to higher willingness to recommend Korean medicine treatment to others. Based on such results, the expansion of the role of Korean medicine could be understood.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제25권2호
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• pp.65-72
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• 2014

Objectives : The objective of this study was to evaluate the treatment duration and adherence of osmotic-controlled release oral delivery system (OROS) methylphenidate for treatment of attention-deficit hyperactivity disorder (ADHD). Methods : A total of 843 children with ADHD were recruited : 213 children (25.3%) who had previously taken medications for ADHD and 630 drug-na$\ddot{i}$ve children (74.7%) were recruited. The dosage was adjusted according to the clinician's judgment. The primary efficacy endpoint of this study was treatment retention rate, which was estimated at Week 12 and Week 20 using the Kaplan-Meier curve. The Swanson, Nolan and Pelham-IV (SNAP-IV), Clinical Global Impression-Severity (CGI-S), Clinical Global Impression-Improvement, and the side effect rating scale were measured at every visit. Remission rates were presented based on SNAP-IV and CGI-S, respectively. Results : The treatment retention rate at 12 weeks and at 20 weeks was 76.2% and 66.8%, respectively. Divided according to 6-8, 9-11, 12-14 and 15-18 years of age, younger children tended to show a statistically higher treatment retention rate (p=.02). Based on SNAP-IV and CGI scores, children with better response to medication showed tendencies of statistically higher treatment retention rate. The most common adverse events included loss of appetite (7.1%) and insomnia (3.3%). There was no serious adverse event related to the treatment, such as death. Conclusion : The use of OROS methylphenidate for treatment of ADHD was safe and tolerable for children. In this study, lower age and better treatment response showed a statistically significant relationship with higher treatment adherence. Boys showed a trend of high treatment adherence. The treatment adherence at 20 weeks was satisfactory, however, the treatment adherence after 20 weeks showed a sharp decrease. Therefore, treatment persistence for six months after the beginning of ADHD treatment is important. In addition, the positive role of psycho-education for children and parents is necessary for increasing treatment adherence.

• International Journal of Industrial Entomology and Biomaterials
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• 제12권2호
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• pp.51-56
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• 2006

Use of products containing phytoecdysteroid (PE) as active principle has become popular in prominent sericultural areas of India for hastening larval maturation events and synchronizing cocoon spinning activities as an obvious advantage is assured. At times, the present recommendation of administering PE at the onset of spinning results in peak labour requirement at odd hrs. To enable making recommendation for the use of PE on $multi{\times}bivoltine$ silkworm hybrids based on the climatic conditions prevailing in different areas especially with regard to temperature, the experiment was taken up to determine proper treatment times so that the induced spinning will be more orderly and the labour can be leveraged more efficiently. Different brackets of low ($18-22^{\circ}C$), medium ($24-28^{\circ}C$) and high ($29-32^{\circ}C$) temperature were simulated during the latter half of V larval instar and cocoon spinning. PE was administered to $multi{\times}bivoltine$ silkworm ($BL67{\times}CSR101$) hybrid batches as per the recommended dose at three different times viz., 10 am, 4 pm and 10 pm. Three replicates of 100 larvae were maintained for each treatment. Absolute controls were also maintained in each temperature range to compare the results. Cumulative maturation percentage was recorded at 6 hrs interval to ascertain peak mounting span. The influence of the treatment on the cocoon traits also was studied. Based on the peak mounting span, it was evident that in low temperature 10 pm treatment would be better. In medium and high temperature, treatment at 4 pm proved to be a better option. The influence of the treatment times at different temperature range on labour management is discussed.

• 대한간호학회지
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• 제50권3호
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• pp.369-384
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• 2020

Purpose: The purpose of this study was to analyze anxiety and depression among infertile women at different time points during the first In Vitro Fertilization (IVF) or Intracytoplasmic Sperm Injection (ICSI) treatment through a systematic review and meta-analysis. Methods: Seven out of 3,011 studies were included for meta-analysis. To estimate the effect size, a meta-analysis of the studies was performed using the RevMan 5.3 program. We compared the measurement outcomes at three time points: before the start of treatment (T0), cancellation of treatment after pregnancy detection (T2), one to six months after treatment (T3). The effect size used was the standardized mean difference (SMD). Results: In comparing the different time points of the pregnant women from their cycle, significantly lower levels of depression were found at T2 than at T0. In non-pregnant women, anxiety at T2 and depression at T2 and T3 were significantly higher than those at T0. At T2 and T3, the non-pregnant women reported higher levels of anxiety and depression compared with the pregnant women. Conclusion: Anxiety and depression in infertile women undergoing the first IVF or ICSI are associated with the time points and pregnancy status after treatment. These findings suggest that attention should be paid to helping infertile women prepare for and cope with treatment and treatment failure.

• 대한약침학회지
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• 제12권4호
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• pp.77-88
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• 2009

Objectives : The purpose of this study was to compare the effect of acpuncture and electro-acupuncture of low(EA(L)) and high(EA(H)) frequency at Haegye(ST41) on intestinal hypomotility induced with loperamide in rats. Methods : We made suppressed state of intestinal motility with loperamide in rats and carried out needle retention acupuncture, low frequency electro-acupuncture and high frequency electro-acupuncture at ST41 in rats devided into pre-treatment group and post-treatment group. We fed charcoal to them after the treatment and measured the travel rate of charcoal in the gastrointestinal track to analyze which treatment is more effective in state of intestinal hypomotility. Results : None of acupuncture, EA(L) and EA(H) at ST41 had significant influences on intestinal motility of rat in normal state. Needle retention at ST41 did not significantly increase intestinal motility suppressed with loperamide in rats. Pre-treatment of EA(L) and EA(H) at ST41 significantly increased intestinal motility suppressed with loperamide in rats. Post-treatment of EA(L) and EA(H) at ST41 did not have significant influences on intestinal motility of rat in normal state. Conclusions : These results suggest that treatment of EA(L) and EA(H) at ST41 may be effective on gastric disorders such as intestinal hypomotility and its effect had more prevention than cure. Further study is necessary to know more effects of ST41 and electro-acupuncture of low and high frequency.

• 보건행정학회지
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• 제9권3호
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• pp.70-94
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• 1999

This paper was performed for a cost-effectiveness analysis of pharmacologic treatment of hypercholesterolemia. Agents modeled were cholestyramine, gemfibrozil. bezafibrate, lovastatin, pravastatin, simvastatin. Pharmacologic effectiveness was estimated by regression from reported clinical trials. Pharmacologic effects were expressed as the percent change of blood cholesterol level. Cost estimates included patients' travel expenses and time loss as well as resource consumption in the health care sector. Bezafibrate was the most efficient agent for reducing total cholesterol levels, having an cost over 1 year of ￦31.400 per percent reduction in total cholesterol. Simvastatin (10mg/d) was also efficient(￦33,100 per percent reduction). Chole styramine(8g/d) was least efficient at ￦90,200. For low-density lipoprotein cholesterol. simvastatin(10mg/d) was most efficient, at ￦23,200 per percent reduction, followed by lovastatin(20mg/d) at ￦28,000. Gemfibrozil was least efficient at ￦77,800 per percent reduction. For high-density lipoprotein cholesterol. bezafibrate(400mg/d) was most efficient at ￦39,300 per percent increase of high-density lipoprotein cholesterol. Cholestyramine was least efficient at ￦514,700. Analyses combining low-density lipoprotein cholesterol and high-density cholesterol effects suggest that bezafibrate(600mg/d) and simvastatin (10mg/d) were most efficient for reducing cardiovascular risk. The cost-effectiveness analysis results show that both simvastatin and bezafibrate could be efficient treatment. Simvastatin provide more effective treatment at higher cost, whereas bezafibrate is more cost-effective, as it may be less effective, at lower cost. Therefore, clinicians should choose reasonable treatment according to the patient's needs This pharmacoeconimc analysis will provide a guideline for efficient pharmacologic treatment and also be reference data for pricing new drugs.

• 한국식품과학회지
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• 제37권3호
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• pp.372-376
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• 2005

중온 열처리에 의한 후지 사과의 품질 개선을 위하여 임계 열처리 조건을 설정하였고, 임계 조건에서의 호흡 및 품질 특성을 조사하였다. 후지 사과의 온도에 따른 임계시간은 $40^{\circ}C$에서 180분, $45^{\circ}C$에서 60분, $50^{\circ}C$에서 25분, $55^{\circ}C$에서 3분, $60^{\circ}C$에서 1분, $65^{\circ}C$에서 20초였다. 호흡 특성에 대한 연구로 열처리 시 사과 내부의 가스 조성변화를 조사한 결과, 탄산가스 농도는 40, 45 및 $50^{\circ}C$의 경우 처리에 따라 급격한 증가 경향을 보인 후 저장 중 다시 감소하였으며, 반면 55, 60 및 $65^{\circ}C$ 처리에서는 처리직후부터 7일 후 까지 큰 변화를 나타내지 않았다. 열처리 사과의 산소가스 농도는 탄산가스 농도와 반대 경향을 나타내었다. 에틸렌 농도는 40, 45 및 $50^{\circ}C$에서 열처리한 사과의 경우 처리 직후 그 농도가 급격히 상승하였다가 처리1일 후부터 대조구보다 낮은 값을 나타내었다. 경도는 처리 7일째 $45^{\circ}C$ 및 $50^{\circ}C$에서 처리한 사과의 경우 대조구보다 각각 6.42%와 10.53%의 높은 값을 나타내었다.

• 대한족부족관절학회지
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• 제17권1호
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• pp.52-59
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• 2013

Purpose: The purpose of this study is to evaluate treatment results of multidisciplinary approach of critical ischemic limb with diabetic foot. Materials and Methods: From March 2005 to March 2012, 674 diabetic foot patients were analyzed. Among them, 85 patients were neuroarthropathic type, 383 patients were infectious type, and 206 patients were ischemic type. The subjects were 206 patients who had critical ischemic limbs and major or minor amputations were done. Various single or combined treatment method before amputation was performed. We investigated their ABI, HbA1c, main occlusion lesion, limb salvage and hospitalization period by various treatment method. Results: Major amputation was 27 cases, minor amputation was 179 cases. Mean HbA1c was 8.2%, and mean ABI was 0.66. Main occlusion lesion was 6 cases at common iliac artery, 13 cases at external iliac artery, 9 cases at internal iliac artery, 11 cases at common femoral artery, 23 cases at deep femoral artery, 52 cases at superficial femoral artery, 35 cases at popliteal artery, 40 cases at posterior tibia artery, 35 cases at anterior tibial artery, 28 cases at peroneal artery, and 13 cases at dorsalis pedis artery. Major amputations were decreased, minor amputations were increased, and hospitalization period was reduced by treatment of multidisciplinary approach. Conclusion: Treatment of multidisciplinary approach, which include preoperation percutaneus transluminal angioplasty, vascular surgery, and amputation, of critical ischemic limb with diabetic foot had advantages of limb salvage and hospitalization period reduction.

• 한국생활과학회지
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• 제9권4호
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• pp.483-489
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• 2000

The purpose of this study is to verify the effect of cellulase treatment on crease resistance of cotton. Cotton fabrics was treated with cellulase under different concentration at $50^{\circ}C$ for 40 min. Also to compare the effect of DMDHEU treatment, DMDHEU treatment was conducted before and after cellulase treatment, also with cellulase. Weight loss, crease resistance and tentile strength of each samples were measured and compared. Maximum weight loss showed at 1g/l con. with 40 min. treatment. Cellulase enzyme treatment was more effective than DMDHEU in the crease resistance and tensile strength. Crease resistant of cotton which treated under different condition with cellulase and DMDHEU showed in the order of cellulase+DMDHEU> cellulase> DMDHEU treatment. Also, tensile strength showed in the order of cellulase> cellulase+DMDHEU> DMDHEU. Among those treatment conditions, condition which treated with cellulase considered more effective to increase crease resistance while keeping tensile strength too.

• 조명전기설비학회논문지
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• 제29권12호
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• pp.28-32
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• 2015

In this work, we reported fabrication of sealing the glass substrate using laser treatment at low temperature for electrochemical luminescence (ECL) cell. The laser treatment at temperature is using laser diode. The glass substrate sealing by laser treatment tested at 3-10W, 2-5 mm/s for build and tested. The sealing laser treatment method will allow associate coordination between the two glass substrate was enclosed. The effect of laser treatment to sealing the glass substrate was found to have cracks and air gap at best thickness of about 550-600 im for condition 3 W, 3 mm/s. The surface of sealing was roughness which was not influent to electrodes It can reduce the cracks, crevices and air gaps as well, improves the performance viscosity in butter bus bar electrodes. Therefore, it is more effective viscosity between two FTO glasses substrate.