• Title/Summary/Keyword: Asymmetry technique

Search Result 120, Processing Time 0.025 seconds

Transbilayer Effects of n-Alkanols on the Fluidity of Phospholipid Model Membranes

  • Yun, Il;Kang, Jung-Sook
    • Archives of Pharmacal Research
    • /
    • v.15 no.2
    • /
    • pp.152-161
    • /
    • 1992
  • Selective quenching of 1, 6-diphenyl-1, 3, 5-hexatriene (DPH) by trinitrophenyl groups was utilized to examine the transbilayer fluidity asymmetry of model membranes of phospholipids (SPMVPL) extracted from synaptosomal plasma membrane vesicles (SPMV). The polarization (P), anisotropy (r), limiting anisotropy $(r_\infty$), and order parameter (S) of DPH in the inner monolayer were 0.019, 0.014, 0.018, and 0.047, respectively, greater than calculated for the outer monolayer of SPMVPL. Selective quenching of DPH by trinitrophenyl groups was also utilized to examine the effects of n-alkanols on the individual monolayer structure of SPMVPL. n-Alkanols fluidized the hydrocarbon region of bulk SPMVPL and the potencies of n-alkanols up to 1-nonanon increased with carbon chain length. It appears that the potencies in bilayer fluidization increase by 1 order of magnitude as the carbon chain length increases by two carbon atoms. The cut-off phenomenon was reached at 1-decanol, where further increase in hydrocarbon length resulted in a decrease in pharmacological activity. The n-alkanols had greater fluidizing effects on the outer monolayer as compared to the inner monolayer of SPMVPL, even though these selective effects tended to become weaker as the carbon chain length increased. Thus, it has been proven that n-alkanols exhibit selective rather than nonselective fludizing effects within transbilayer domains of SPMVPL.

  • PDF

Development of a Customized Helmet Design System for Patients with Plagiocephaly (사두증 환자를 위한 맞춤형 헬멧 몰드 디자인 시스템 개발)

  • Kang, Yeonghoon;Park, Hyeryeon;Kim, Sungmin
    • Fashion & Textile Research Journal
    • /
    • v.24 no.4
    • /
    • pp.443-450
    • /
    • 2022
  • This study developed a three-dimensional helmet mold design software that can design helmets for treating the infant plagiocephaly (flat head syndrome) using three-dimensional head scan data. For this, the three-dimensional head data of sixth SizeKorea body measurement project as well as the data produced by a head modeling software were used to prepare the head shape data of plagiocephaly patients. A total of 14 landmarks and 10 dimensions of heads required for helmet mold shape design and plagiocephaly diagnosis were automatically measured using an anthropometric analysis software. Using the software developed in this study, plagiocephaly can be diagnosed not only visually by three-dimensional head data visualization but also quantitatively by calculating the medically defined indices such as cranial index, which measures the proportions of the head, and the cranial vault asymmetry index, which measures the asymmetry of the head. The basic shape of the helmet mold was automatically generated based on the head scan data. Additionally, it is possible to fine tune the shape of the mold to reflect individual characteristics by using a free form deformation technique. Finally, the designed helmet mold was converted into the data that can be printed on a three-dimensional printer for generating the actual prototype.

The Clinical Study of Muscle Energy Technique (MET) Performed on Sternocleidomastoid Muscle of Acute Nuchal Pain Patients on Meridian Electromyography (급성 경항통 환자의 흉쇄유돌근에 대한 근 에너지 기법(MET) 시술 후의 경근전도 변화 연구)

  • Ahn, Jae-Min;Cho, Dong-In;Park, Dong-Su;Jeong, Su-Hyeon;Kim, Soon-Joong
    • Journal of Korean Medicine Rehabilitation
    • /
    • v.24 no.1
    • /
    • pp.93-100
    • /
    • 2014
  • Objectives To evaluate the clinical utility of MET performed on sternocleidomastoid muscle of acute nuchal pain patients, we measured a change of meridian electromyography. Methods We compared electrical activity before and after MET performed on sternocleidomastoid muscle of acute nuchal pain patients in same group (n=20) in isometric exercise state during five seconds. We analyzed amplitudes and areas of electrical activity and asymmetry index (AI). Results 1. After MET performed on sternocleidomastoid muscle of acute nuchal pain patients, maximum voluntary isomeric contraction (MVIC) was significantly increased more than before MET performed (p<0.005). 2. Comparing with before MET performed on sternocleidomastoid muscle of acute nuchal pain patients, muscle fatigue after MET performed on sternocleidomastoid muscle of acute nuchal pain patients decreased but there was no significant difference. 3. Comparing with before MET performed on sternocleidomastoid muscle of acute nuchal pain patients, asymmetry index (AI) after MET performed on sternocleidomastoid muscle of acute nuchal pain patients decreased but there was no significant difference. Conclusions According to above results, after performing MET on sternocleidomastoid muscle of acute nuchal pain patients, maximum voluntary isomeric contraction (MVIC) increased significantly, so it is certain that performing MET on sternocleidomastoid muscle has a clinical effect.

A Comparison of Pelvic Tilt Before and After Manipulation of Sacroiliac Joint in the Patients with Low Back Pain (요통환자의 천장관절에 대한 도수교정 전과 후의 골반경사 비교)

  • Oh, Seung-Gil;Lee, Jin-Haeng
    • Journal of Korean Physical Therapy Science
    • /
    • v.7 no.2
    • /
    • pp.579-595
    • /
    • 2000
  • The purposes of this study were to compare pelvic tilt before and after manipulation of sacroiliac joint in 31 low back pain patients (11 males, 20 females) with sacroiliac joint dysfunction. The sacroiliac joint of patients was manipulated on the side of anterior pelvic tilt, using the technique described by Stoddard (1962) and Greenmann (1996). I used this technique because it usually eliminated sacroiliac joint dysfunction in one treatment session. SPSS for window computer system was used to analyze the data. Also t-test was performed for comparison of pelvic tilt angle before and after manipulation, and Pearson product-moment correlation analysis was performed for intratester reliability for measurements of pelvic tilt angle before and after manipulation. The result were as follows: 1. Intratester reliability was good for measures of pelvic tilt (r=.98). 2. The pelvic tilt after manipulation was significantly decreased (mean=$3.40^{\circ}$) compared with the pelvic tilt before manipulation (p=.001). All subjects showed asymmetrical right versus left pelvic tilt before manipulation. 40% of subjects showed decreased asymmetrical right versus left pelvic tilt after manipulation, and 60% of subjects showed symmetrical right versus left pelvic tilt after manipulation. I think that pelvic tilt asymmetry with hypomobility due to loss of joint play could be symmetrized by manipulation or mobilization, but pelvic tilt asymmetry with unilateral pelvic muscle shortening could not be symmetrized by manipulation or mobilization without relaxation and stretching of shortened muscles.

  • PDF

Measurement and Excitation Techniques for Modal Testing of Rotating Machinery (회전 기계의 모드 시험을 위한 측정 및 가진 방법)

  • 권계시;이종원
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 1998.04a
    • /
    • pp.238-243
    • /
    • 1998
  • Measurement technique using only one sensor for complex modal testing of the asymmetric rotor is proposed. The reverse directional frequency response function of asymmetric rotor, which is known to be indicative of the degree of asymmetry in a symmetric rotor, is also shown to be identified with simplest technique requiring only one sensor and one excitor. It lessens the testing efforts and its practicality is verified by numerical simulation. The measurement and excitation techniques for complex modal testing are also summarized so that the efficient complex modal testing can be possible according to the kind of rotor system.

  • PDF

Interference Resolving Radio Resource Allocation Scheme in a TDD-OFDMA/FDD-CDMA Hierarchical Over lay Cellular System

  • Lee, Yeonwoo;Kim, Kyung-Ho
    • Journal of Korea Multimedia Society
    • /
    • v.16 no.7
    • /
    • pp.862-869
    • /
    • 2013
  • In order to support a cell-independent traffic asymmetry, the conventional TDD system cannot avoid crossed time slot (CTS) interference. Moreover, the TDD/FDD hierarchical overlay cellular systems is taken into account as a generally accepted cell model in a heterogeneous radio environment. In this paper, we propose an interference resolving radio resource allocation technique in a TDD-OFDMA cellular system that overlays a FDD-CDMA cell. In our proposed scheme, we exploit under-used FDD-CDMA uplink resource by TDD mobile abiding by a region based time slot(TS) allocation which in turn mitigates CTS interference considerably. It is demonstrated that combined with under-used resource utilization scheme based on mobile's location, the proposed technique can reduce CTS interference considerably and support the asymmetric traffic in TDD system.

Start-up In-rush Current Reduction Technique of Asymmetrical Half-Bridge DC/DC Converter for PC Power Supply (PC 파워 서플라이용 비대칭 하프브리지 DC/DC 컨버터의 초기 구동시 돌입전류 제거 기법)

  • Kim Jae-Kuk;Lee Sung-Sae;Oh Won-Sik;Kim Jung-Eun;Moon Gun-Woo;Gil Chang-Hyun;Cho Ja-Ryong
    • Proceedings of the KIPE Conference
    • /
    • 2006.06a
    • /
    • pp.251-253
    • /
    • 2006
  • This paper presents a start-up in-rush current reduction technique of asymmetry half-bridge DC/DC converter for PC power supply. The proposed converter is composed center-tapped half-bridge converter with blocking capacitor. The proposed converter can reduce the severe in-rush current when the proposed converter is power up. The validity of this study is confirmed from the experimental results.

  • PDF

Simultaneous Maxillo-Mandibular Distraction Osteogenesis in Hemifacial Microsomia: a Case Report (상하악에 동시 다발성 골신장술을 이용한 반안면왜소증의 치험례)

  • Kim, Il-Kyu;Park, Jong-Won;Lee, Eon-Hwa;Yang, Jung-Eun;Chang, Jae-Won;Pyun, Yeong-Hun;Ju, Sang-Hyun;Wang, Boon
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.32 no.5
    • /
    • pp.447-453
    • /
    • 2010
  • The hemifacial microsomia is characterized by variable underdevelopment of the craniofacial skeleton, external ear, and facial soft tissues. So, patients with hemifacial microsomia have an occlusal plane canting and malocclusion with facial asymmetry. Distraction osteogenesis (DO) with an intraoral or extraoral device is a technique using tension to generate new bone with gradual bone movement and remodeling. DO has especially been used to correct craniofacial deformities such as a hemifacial microsomia, facial asymmetry, and mandible defect that could not adequately be treated by conventional reconstruction with osteotomies. It has a significant advantage to lengthen soft and hard tissue of underdeveloped site without bone graft and a few complication such as nerve injury or muscle contracture. A 13-years old girl visited our clinic for the chief complaint of facial asymmetry. She had a left hypoplastic maxilla and mandible, occlusal plane canting and malocclusion. We diagnosed hemifacial microsomia and lanned DO to lengthen the affected side. Le Fort I osteotomy, left mandibular ramus and symphysis osteotomy were performed. The internal distraction devices fixed with screw on maxillary and mandibular ramus osteotomy sites. External devices were adapted to lower jaw for DO on symphysis osteotomy site and to upper jaw for rapid maxillary expansion (RME). At 7days after surgery, distraction was started at the rate of 1mm per day for 13days, and after 4months consolidation periods, distraction devices were removed. Simultaneous multiple maxillo-mandibular distraction osteogenesis with RME resulted in a satisfactory success in correcting facial asymmetry as well as occlusal plane canting for our hemifacial microsomia.

STEP OSTEOTOMY TECHNIQUE THROUGH INTRAORAL APPROACH FOR MANDIBULAR DISTRACTION (Callus distraction method를 이용한 하악골 신장술;계단골절단술식의 적용)

  • Kim, Myung-Jin;Yun, Pill-Young;Shin, Dong-Joon;Kim, Soo-Kyung;Kim, Jong-Won;Kim, Kyoo-Sik
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.22 no.2
    • /
    • pp.254-261
    • /
    • 2000
  • Since callus distraction technique was applied clinically for the correction of dentofacial deformity to the patients with hemifacial dysplasia by McCarthy in 1992, many surgeons have tried to apply this method to the maxillofacial region. But this technique has some drawbacks. One of the disadvantages of this technique is extensive scar formation in the facial area, which is a sequelae of extraoral approach for supraperiosteal dissection of the periosteum overlying the mandible. Recently, we have made an effort to perform this technique through intraoral approaches to prevent scar formation on the submandibular area and modified the design of the osteotomy, that is step osteotomy technique, to increase the raw bone surface on both osteotomized segments. The rationale for the application of this step osteotomy technique is to increase the amount of regenerated bone and the length of distraction, to avoid damage of inferior alveolar neurovascular bundle, and to increase initial stability of the splitted segments. Step osteotomy procedure can be done with fine micro-osteotomy saw through subperiosteal tunneling. Extraoral pins should be inserted before making the osteotomy. Since 1994 we have applied this technique at 8 sites In 5 patients with mandibular deficiencies: 2 cases of hemifacial microsomia, 1 case of developmental facial asymmetry and 2 cases of mandibular bony defect. Mandibular elongation have been achieved from 12 to 20mm in length. 1 out of 8 site, we experienced non-union in the case of mandibular body defect. Some skeletal relapse and growth retardation phenomenon have been observed in some cases with the longest follow-up of 48 months.

  • PDF

Chair side measuring instrument for quantification of the extent of a transverse maxillary occlusal plane cant

  • Naini, Farhad B.;Messiha, Ashraf;Gill, Daljit S.
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.41
    • /
    • pp.21.1-21.3
    • /
    • 2019
  • Background: Treatment planning the correction of a transverse maxillary occlusal plane cant often involves a degree of qualitative "eyeballing", with the attendant possibility of error in the estimated judgement. A simple chair side technique permits quantification of the extent of asymmetry and thereby quantitative measurements for the correction of the occlusal plane cant. Methods: A measuring instrument may be constructed by soldering the edge of a stainless steel dental ruler at 90° to the flat surface of a similar ruler. With the patient either standing in natural head position, or alternatively seated upright in the dental chair, and a dental photographic retractor in situ, the flat under-surface of the horizontal part of this measuring instrument is placed on a unilateral segment of a bilateral structure, e.g. the higher maxillary canine orthodontic bracket hook. The vertical ruler is held next to the contralateral canine tooth, and the vertical distance measured directly from the canine bracket to the flat under-surface of the horizontal part of the measuring instrument. Results: This vertical distance quantifies the overall extent of movement required to level the maxillary occlusal plane. Conclusions: This measuring instrument and simple chair side technique helps to quantify the overall extent of surgical levelling required and may be a useful additional technique in our clinical diagnostic armamentarium.