• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.1
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• pp.43-52
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• 2017

EtOAc fractions of Magnolia obovata (M. obovata) Bark extracts were studied for the potential ingredient as a safe and effective whitening cosmetic material. The concentration of active substances honokiol was determined by HPLC. In vitro, the fractions reduced the extracellular and intracellular melanin contents in B16F10 cells in dose dependently and inhibited extracellular melanin secretion ($IC_{50}=11.05{\mu}g/mL$). The $12.5{\mu}g/mL$ treatment of maximum concentration effectively inhibited up to about 60% to the amount of extracullular melanin. Also, the $12.5{\mu}g/mL$ treatment of maximum concentration effectively inhibited up to about 59% to the amount of intracullular melanin ($IC_{50}=10.85{\mu}g/mL$). The $IC_{50}$ value of ${\alpha}-arbutin$ used as a positive control was $59.99{\mu}g/mL$. So, EtOAc fractions of M. obovata Bark extracts showed whitening effect when compared with the non-treatment group. In case of in vivo study, Cosmetic cream with EtOAc fractions of M. obovata Bark extracts was approved by Ethics committee of KDRI (IRB number: KDRI-IRB-1537). As a result in progress for skin sensitization as well as assessment of skin irritation through repeated patch test, skin allergens was identified as non sensitizing agents. Also, cosmetic cream with EtOAc fractions of M. obovata Bark extracts showed significant topical whitening effect and reliable skin safety when compared with the non-treatment group. In conclusion, EtOAc fractions of M. obovata Bark extracts may be a useful cosmetic ingredient for effective skin whitening.

• Journal of Bio-Environment Control
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• v.31 no.4
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• pp.423-431
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• 2022

Due to increase of interest in 'carbon neutrality', attempts at agricultural use of CO₂ are increasing. In this study, we used the dry-ice made by CO₂ as by-product in thermoelectric power plant on CO₂ fertilization for production of leafy vegetable in greenhouses. The dry-ice was supplied on three leafy vegetable farms (Allium tuberosum Rottl. ex Spreng, Aster scaber, and Oenanthe stolonifera DC.) located in Hadong, Gyeongsangnamdo. Two greenhouses were used in each leaf vegetable crops, one greenhouse used as the control (non-treatment), other greenhouse used as supplied CO₂. For CO₂ fertilization, a gas sublimated from dry ice was supplied to the greenhouse using a specially designed prototype supply machine. A. tuberosum greenhouse has no difference of CO₂ concentration between the control, and CO₂ fertilization and shown high CO₂ concentration both greenhouses. However, the CO₂ concentrations in A. scaber and O. stolonifera greenhouses were increased in CO₂ fertilization treatment. The growth of A. scaber and O. stolonifera were increased in CO₂ fertilization, and the yield also increased to 36% and 25% than the control, respectively. As a result of economic analysis, the A. scaber has increase of income rate, however A. tuberosum and O. stolonifera has decreased income rate. Thus, the use of the dry-ice made by CO₂ as by-product in thermoelectric power plant has possibility to increase productivity of the leafy vegetable in greenhouse and have agricultural use value.

• The Journal of Korean Society for Radiation Therapy
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• v.34
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• pp.83-92
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• 2022

Purpose: To evaluate usefulness of Tomotherapy and Halcyon VMAT treatment in radiation therapy for bi-breast cancer Materials and Methods: For 10 patients with bi-breast cancer, volumetric modulated arc therapy(VMAT) treatment plan was established using helical Tomotherapy(Accuray. USA) with field width of 5.0-cm and pitch of 0.287, and Halcyon(Varian Medical System, Palo Alto, CA, Version 3.0 USA) of 6arc and 8arc. Prescribed dose was 42.4 Gy/16, and V _40.3Gy of Planning Target Volume(PTV) was 90%. The quality of plan was evaluated by comparing the dose to tumor and normal organs, and the efficiency was evaluated by comparing total MU and beam on time. Results: About three treatment plans(Tomotherapy, Halcyon 6Arc VMAT, Halcyon 8Arc VMAT) , the mean homogeneity index(H.I) of PTV were 1.07, 1.10, 1.11, and the mean conformity index(C.I) of PTV were 1.21, 1.16, 1.17, respectively. The average value of the dose assessment item for a normal organ is V _5Gy(%) of both lung was 36.3, 31.2, 29.7, and V _15Gy(%) were 18.6, 15.5, 14.6, respectively. The mean heart dose(Gy) were 4.17, 2.69, 2.51. Total MU were (7498.6, 2494.2, 2471.5), and beam on time(sec) were 462.5, 195.4, 198.0. Conclusion: Halcyon VMAT showed similar quality of treatment plan compared to helical Tomotherapy, while also protecting normal organs. In addition, the efficiency of radiotherapy increased due to a decrease in Beam On Time and MU.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.5
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• pp.680-689
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• 2016

The present study evaluated the validation method for isoflavone contents of fermented soybean extracts by bioconversion as well as their antioxidant activities. Our results show that the total isoflavone contents of non-fermented and fermented soybean extract ranged between 119.8 to $637.7{\mu}g/g$ and between 567.3 to $2,074.6{\mu}g/g$, respectively. Moreover, fermented soybean extracts had higher contents of isoflavone aglycones, including daidzein, glycitein, and genistein than non-fermented soybean extracts as well as lower contents of isoflavone glucosides such as daidzin, glycitin, and genistin. FRAP and ORAC values ranged between 0.15 to 0.22 and between 195.24 to $753.79{\mu}M$ Trolox equivalents/g in non-fermented and fermented soybean extracts, respectively. These results indicate that fermented soybean extracts had higher total isoflavone contents and antioxidant activities than non-fermented soybean extracts. Bioconversion process in this study may have the potential to produce isoflavone-enriched natural antioxidant agents with high added value from soybean matrices.

• Korean Journal of Soil Science and Fertilizer
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• v.43 no.5
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• pp.728-733
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• 2010

This study was carried out to estimate carbon emission using LCA and to establish LCI database of potato production system. Potato production system was categorized into the fall season potato and the spring season potato according to potato cropping type. The results of collecting data for establishing LCI D/B showed that input of fertilizer for fall season potato production was more than that for spring season potato production. Input of pesticide for spring season potato production was much more than that for fall season potato production. The value of field direct emission ($CO_2$, $CH_4$, $N_2O$) were 2.17E-02 kg $kg^{-1}$ for spring season potato and 2.47E-02 kg $kg^{-1}$ for fall season potato, respectively. The result of LCI analysis focussed on the greenhouse gas (GHG), it was observed that carbon footprint values were 8.38E-01 kg $CO_2$-eq. $kg^{-1}$ for spring season potato and 8.10E-01 kg $CO_2$-eq. $kg^{-1}$ for fall season potato; especially for 90% and 6% of $CO_2$ emission from fertilizer and potato production, respectively. $N_2O$ was emitted from the process of N fertilizer production (76%) and potato production (23%). It was observed that characterization of values of GWP were 8.38E-01 kg $CO_2$-eq. $kg^{-1}$ for spring season potato and 8.10E-01 kg $CO_2$-eq. $kg^{-1}$ for fall season potato.

• Journal of the Korean Society of Groundwater Environment
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• v.5 no.3
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• pp.129-140
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• 1998

In this study two sites were selected to investigate groundwater contamination and spatial relationship between pollution level and its source. One is the Asan area, agricultural district where pollution sources are scattered. The other is the Gurogu area of Seoul city, industrial district where industrial complex and residential areas are located. Groundwater samples collected from these districts were analysis for chemical constituents. The attribute value files of the chemical constituents of groundwater and the spatial layers have been constructed and the pollution properties have been investigated to find out spatial relationships between the groundwater constituents and pollution sources using CIS. Relatively high contents of Si and HCO$_3$ in groundwater from the Asan area reflect the effect of water-rock interaction, whereas high contents of Cl, NO$_3$, SO$_4$and Ca in groundwater from the Gurogu area are due to the pollution of various sources. Pollution over the critical level of Korean Dinking Water Standard has been investigated from 15 sampling sites out of 40 in the Asan area, and 33 sampling sites out of 51 in the Gurogu area. There is pollution of NO$_3$, Cl, Fe, Mn, SO$_4$and Zn in groundwater from the Gurogu area, and that of NO$_3$, SO$_4$and Zn in groundwater from the Asan area. Principal pollution in both areas is NO$_3$contamination. Deep groundwater from the Asan area is not contaminated with NO$_3$except for one site and most of shallow groundwater near the potential point sources such as factory and stock farm is contaminated seriously. Groundwater from the Gurogu area has been already polluted seriously considering the fact of contamination of deep groundwater. This study reports a spatial relationship between the pollution level and pollution source using GIS.

• Journal of Korea Water Resources Association
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• v.54 no.9
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• pp.719-730
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• 2021

The objective of this study is to develop the water quality and aquatic ecosystem model for Andong lake using SWAT-WET (Soil and Water Assessment Tool-Water Ecosystem Tool) and to evaluate the applicability of WET. To quantify the pollutants load flowing into Andong lake, a watershed model of SWAT was constructed for Andong Dam basin (1,584 km²). The calibration results for Dam inflow and water quality loads (SS, T-N, T-P) were analyzed that average R² was more than 0.76, 0.69, 0.84, and 0.60 respectively. The calibrated SWAT results of streamflow and nutrients concentration was used into WET input data. WET was calibrated and validated for water temperature, dissolved oxygen, and water quality concentration (T-N, T-P) of Andong lake. The WET calibrated results was analyzed that PBIAS was +19%, -13%, +4%, and +26.5% respectively and showed that it was simulated to a significant level compared with the observation data. The observed dry weight (gDW/m²) of zoobenthos was less than 0.5, but the average value of simulation was analyzed to be 0.8, which is because the WET model considers zoobenthos with a broader concept. Although accurate calibration is difficult due to the lack of observed data, SWAT-WET can analyze the effects of environmental change in the upstream watershed on the lake based on long-term simulation based on watershed model. Therefore, the results of this study can be used as basic data for managing the aquatic environment of Andong lake.

• Journal of Nutrition and Health
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• v.55 no.1
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• pp.155-173
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• 2022

Purpose: This study was undertaken to update the Nutrition Quotient for Elderly (NQ-E), which reflects dietary quality and behavior among Korean older adults. Methods: The first 29 items of the measurable food behavior checklist were obtained from a previous NQ-E checklist, recent literature reviews, and national nutrition policies and recommendations. One-hundred subjects (50 men and 50 women) aged ≥ 65 years living in the Seoul Metropolitan Area, including Gyeonggi Province, completed a pilot survey from March to April 2021. Based on the results of the pilot study, we conducted factor analysis and frequency analysis to determine whether the items of the survey were properly organized and whether the distribution of answers for each evaluation item was properly distributed. As a result, we reduced the number of items on the food behavior checklist and used 23 items for the national survey. Nationwide, 1,000 subjects (472 men and 528 women) aged > 65 years, completed the checklist survey, which was applied using a face-to-face survey method from May to August 2021. The construct validity of the NQ-E 2021 was assessed using confirmatory factor analysis, LISREL. Results: Seventeen food behavior checklist items were selected for the final NQ-E 2021. Checklist items addressed three factors: balance (8 items), moderation (2 items), and practice (7 items). Standardized path coefficients were used as the weights of items to determine nutrition quotients. NQ-E and three-factor scores were calculated according to the weights of questionnaire items. Conclusion: The updated NQ-E 2021 produced by structural equation modelling provides a suitable tool for assessing the dietary quality and behavior of Korean older adults.

• Korean Journal of Construction Engineering and Management
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• v.15 no.1
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• pp.87-100
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• 2014

Environmental problems and the shortage of natural resources are currently gathering more attention in Korea and international countries. With these problems, it is reported that most current domestic buildings are emitting approximately 138 million tons of greenhouse gas. According to a recent report from the investigation of Korean housing population, the total number of households is approximately 12.9 millions, and the apartments that were built more than 15 years ago amounted to 3.1 millions. This shows that the rates of old apartment housings are increasing. Therefore, it is necessary to consider the deteriorated facilities and environmental improvement. Also, the construction industry is benefited by improving these housings which may need either remodeling or reconstruction. Environmental friendly buildings are a rising consideration for remodeling and reconstruction projects; it helps to determine many business matters in construction. The main purpose of this research is to improve environmental condition in apartments with comparison analysis between remodeling and reconstruction alternatives. This research is focused on characteristics of remodeling and reconstruction and it sets up the same condition with each level in order to evaluate the value of environmental friendliness and analyze its definition. The result of this research provides a unique emitting rate at a novel framework and this will cause the reduction of $CO_2$. It is analyzed that the remodeling construction can reduce the great amount of $CO_2$. Therefore, it will be a good decision guideline in selecting the most eco-friendly alternative to improve environment for building construction. Although reconstruction is a popular alternative nowadays in Korea, this research can provide a reason why decision makers should put more emphasis on remodeling as an environment-friendly alternative.

• Journal of the Korean Society of Radiology
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• v.15 no.6
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• pp.803-811
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• 2021

In this study, the exposure amount of IASCC test worker was evaluated by applying the process simulation technology. Using DELMIA Version 5, a commercial process simulation code, IASCC test facility, hot cells, and workers were prepared, and IASCC test activities were implemented, and the cumulative exposure of workers passing through the dose-distributed space could be evaluated through user coding. In order to simulate behavior of workers, human manikins with a degree of freedom of 200 or more imitating the human musculoskeletal system were applied. In order to calculate the worker's exposure, the coordinates, start time, and retention period for each posture were extracted by accessing the sub-information of the human manikin task, and the cumulative exposure was calculated by multiplying the spatial dose value by the posture retention time. The spatial dose for the exposure evaluation was calculated using MCNP6 Version 1.0, and the calculated spatial dose was embedded into the process simulation domain. As a result of comparing and analyzing the results of exposure evaluation by process simulation and typical exposure evaluation, the annual exposure to daily test work in the regular entrance was predicted at similar levels, 0.388 mSv/year and 1.334 mSv/year, respectively. Exposure assessment was also performed on special tasks performed in areas with high spatial doses, and tasks with high exposure could be easily identified, and work improvement plans could be derived intuitively through human manikin posture and spatial dose visualization of the tasks.