• Journal of Veterinary Clinics
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• v.36 no.4
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• pp.212-218
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• 2019

This study evaluates the drug delivery and biocompatibility of latanoprost imbedded disk in rabbit eye by assessing pharmacokinetics (PK), clinical signs, and histopathologic findings. During 84 days of experimental period, 48 New Zealand Rabbit (NZW) eyes were divided into control group which received no treatment and test material group which latanoprost were implanted intrasclerally. Pharmacokinetic assessment was performed to evaluate the drug delivery for 3 months. For biocompatibility, clinical signs were observed and histopathological analysis was done at 3 months post-operatively. The concentration of latanoprost in the iris tissue was maintained during the experimental period and the highest level of latanoprost was found at 4 weeks. However, the latanoprost was not found in the aqueous humor. Macroscopically, there was no evidence of clinical signs except for temporary hyperemia, neovascularization and edema immediately after surgery. On histopathological examination, there were no abnormal findings such as hyperemia, neovascularization, and edema in the eye tissues. The latanoprost imbedded disks has effectively released the drug into the adjacent tissue with high compatibility. Therefore, this study suggests that the drug delivery system with intrascleral latanoprost imbedded implants might be a novel approach as a treatment option for glaucoma.

• Korean Journal of Applied Biomechanics
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• v.30 no.4
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• pp.301-309
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• 2020

Objective: This study aimed to investigate the effect of white noise on dynamic balance in patients with stroke during walking. Method: Nineteen patients with chronic stroke (age: 61.2±9.8 years, height: 164.4±7.4 cm, weight: 61.1±9.4 kg, paretic side (R/L): 11/8, duration: 11.6±4.9 years) were included as study participants. Auditory stimulus used white noise, and all participants listened for 40 minutes mixing six types of natural sounds with random sounds. The dynamic balancing ability was evaluated while all participants walked before and after listening to white noise. The variables were the center of pressure (CoP), the center of mass (CoM), CoP-CoM inclined angle. Results: There is a significant increase in the antero-posterior (A-P) CoP range, A-P inclination angle, and gait speed on the paretic and non-paretic sides following white noise intervention (p<.05). Conclusion: Our findings confirmed the positive effect of using white noise as auditory stimulus through a more objective and quantitative assessment using CoP-CoM inclination angle as an evaluation indicator for assessing dynamic balance in patients with chronic stroke. The A-P and M-L inclination angle can be employed as a useful indicator for evaluating other exercise programs and intervention methods for functional enhancement of patients with chronic stroke in terms of their effects on dynamic balance and effectiveness.

• Asian Journal of Innovation and Policy
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• v.4 no.1
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• pp.55-75
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• 2015

The purpose of this study is to find what competence determines the employment of college students using data from the K-CESA (Korea Collegiate Essential Skills Assessment) of a Korean university during 2009-2014. This test comprises of 6 categories of competence: self-management, global readiness, interpersonal relationship, resource/information/technology handling, communication and comprehensive reasoning. In addition to these competences, we add the comprehensive variable, grade point average. In order to identify the qualities of employment, employment was classified into 3 types: all employment, employment in decent jobs and employment in the top 500 companies. Results are as follows: For all employment and decent jobs, GPA and comprehensive reasoning were the meaningful variables. However in case of the top 500 companies, interpersonal relationship was added. Based on the analysis, this study suggests the fundamental concepts of college students' job competence: job specific competence, job basic competence, and basic competence.

• STI Policy Review
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• v.1 no.4
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• pp.29-39
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• 2010

Science, technology, society and humanities (STSH) fusion research is aimed at creating new research areas and methods that can resolve complicated issues in society that cannot be solved by a single academic discipline. This study identifies initiatives that can promote STSH fusion research in Korea. We review the definition and characteristics of STSH fusion research to analyze the necessity of STSH fusion research with a focus on the structural changes in the S&T environment. The emergence and diffusion of generic technologies, transition to post catch-up innovation mode, and the evolution of policy to the third generation innovation policy are identified as notable changes. This paper briefly reviews the status of fusion research underway and presents initiatives to promote STSH fusion research.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2003.05a
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• pp.48-49
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• 2003

• Proceedings of the Korea Technology Innovation Society Conference
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• 2001.11a
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• pp.133-140
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• 2001

소기업의 프로세스 심사는 재정 및 인적 자원의 한계로 실행되기 어려운 여건을 가지고 있다. 이러한 소규모 조직의 프로세스 심사 과정과 심사 대상 프로세스는 일반적으로 중견 또는 대기업을 대상의 그것과는 차별적으로 적용되어야 한다. 본 연구에서는 소규모 조직의 소프트웨어 프로세스 개선을 위한 프로세스 심사 방법을 제안하였고 실제로 2개 기업에 적용하여 보았다. 여기에서 심사 대상 프로세스를 선정하는 것이 중요한 부분을 차지하는데, 이는 해당업체가 주관적으로 필요하다고 생각하는 "업체선정" 프로세스와 전문가가 객관적으로 중요하다고 판단하는 "전문가선정" 프로세스를 조합하는 방법을 취했다. 여기서 "전문가선정" 심사 대상 프로세스의 선정은 전문가들을 대상으로 한 2차에 걸친 델파이 설문조사 결과를 분석한 최종 산출물이다. 그리고, 선정된 심사 대상 프로세스를 중심으로 두 업체의 소프트웨어 프로세스를 시범적으로 심사하여 보았다.체의 소프트웨어 프로세스를 시범적으로 심사하여 보았다.

• Journal of Korea Technology Innovation Society
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• v.4 no.2
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• pp.143-156
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• 2001

Technology evaluation is one of the key issues in discussions on the development of evaluation methods. This paper deals with some methods for the evaluation of new energy technologies, which were appraised by MAUT from various outlooks: economics, environment, and resource saving. MAUT is considered to be the proper method for evaluating the next generation energy technology, since it can evaluate alternatives that comprise basic criteria. This paper analyzes a priority order of 13 new energy technologies selected by groups of energy technology experts through two steps. Converted utility technology shows the highest value in economics.

• Knowledge Management Research
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• v.11 no.5
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• pp.25-36
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• 2010

It is widely known that KMS (Knowledge Management System) plays a role of facilitator that contributes to upgrading the organizational performance. Despite this widespread belief, actual operation of KMS has been stalled at the level of being used only for the plain knowledge administration, not reaching the level of utilizing KMS strategically. In this sense, this case study suggests three successful KMS operation strategies-personalization strategy, socialization strategy, and technological strategy. Cases adopted in this study include HIRA(Health Insurance Review & Assessment Service) and KORAIL (Korea Railroad) where KMS has been successfully utilized to improve their organizational innovation and performance as well. Through scrutinizing the two cases, it was concluded that the proposed three KMS operation strategies have potentials of being generally applied to other KMS operation cases.

• Proceedings of the Korea Technology Innovation Society Conference
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• 2017.05a
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• pp.501-535
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• 2017

이 연구는 한국 학계가 그간 많은 성장을 일구어 왔음에도 질적 수준에 대해서 지속적인 비판을 받고 있는 현 상황에 의문을 갖고 연구를 시작하였다. 최근 연구의 질적 수준 제고를 위해 연구개발 성과평가 제도가 전면적인 변화를 겪고 있음에도 정작 한국 학술연구의 질적 수준 문제가 어떠한 양상으로 나타나고 있는지 과학적인 증거를 제시하고자 하는 노력은 지금까지 매우 미흡했다. 이에 이 연구에서는 한국 연구의 양적 성장과 질적 성장 간의 괴리가 어떠한 양상으로 나타나는지 가시적인 일면을 제시하기 위하여 한국 연구자가 포함된 모든 SCI 논문을 수집하고 이를 대학, 출연연, 기업, 해외기관, 기타 소속 저자로 구분하여 양적 추세와 피인용횟수 추세를 비교하고자 하였다. 분석결과 해외기관 소속 저자와 국내기관 소속 저자 간에 유의미한 수준의 피인용횟수 격차가 나타나고 있으며, 이러한 격차는 시간의 흐름에 따라 해소되지 않고 있는 것을 확인하였다. 또한 분야별로 격차가 다르게 나타나 생화학 분자생물학이나 신경과학 신경학 등의 분야에서 피인용횟수의 격차가 보다 높게 나타나고 있었다. 이러한 결과는 최근 한국 공공연구 영역에서 전면적으로 일어나고 있는 질적 평가체제로의 전환 움직임에 대해서 그 세부적인 설계와 차등 요건의 적절성에 대해 다시 한 번 생각해볼 수 있는 계기를 제공한다.

• Journal of Applied Reliability
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• v.11 no.1
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• pp.59-81
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• 2011

Six Sigma has been disseminated into a variety of areas. It is believed that a stepwise understanding of Six Sigma's DMAIC is required for successes of unit projects. Meanwhile, infra-structure factors, such as leadership, organization, personnel management, educational system, etc., are also important to safely implant the Six Sigma into the whole enterprise and to thoroughly create the culture of innovation and enterprise. Careful analysis of those elements makes it possible to draw common connection between Project Management and the Six Sigma. This study drives the success elements for the successful adoption of the Six Sigma in the Korea Western Power Co., Ltd., of which management was evaluated as one of the tops based on the results of 2007 Management Innovation Assessment and arranges the similarity of like this factor and Enterprise Project Management. The results of this study are expected to provide a useful guideline for the adoption of the Six Sigma in whole company level.