• 제목/요약/키워드: Assessing

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Comparison of MLE and REMLE of Linear Mixed Models in Assessing Bioequivalence based on 2x2 Crossover Design with Missing data

  • Chung, Yun-Ro;Park, Sang-Gue
    • Journal of the Korean Data and Information Science Society
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    • 제19권4호
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    • pp.1211-1218
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    • 2008
  • Maximum likelihood estimator (MLE) and restricted maximum likelihood estimator (REMLE) approaches are available in analyzing the linear mixed model (LMM) like bioequivalence trials. US FDA (2001) guides that REMLE may be useful to assess bioequivalence (BE) test. This paper studies the statistical behaviors of the methods in assessing BE tests when some of observations are missing at random. The simulation results show that the REMLE maintains the given nominal level well and the MLE gives a bit higher power. Considering the levels and the powers, the REMLE approach is recommended when the sample sizes are small to moderate and the MLE approach should be used when the sample size is greater than 30.

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콘크리트 초기 품질관리를 위한 CIMS의 개발성능 Test (Performance test of Concrete IoT Management System for concrete early-age quality control)

  • 이영준;최윤호;서항구;현승용;한민철;한천구
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2019년도 춘계 학술논문 발표대회
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    • pp.161-162
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    • 2019
  • The aim of the research is analyzing the performance of the concrete IoT management system invented with similar technique from 'G' company to certify the performance of CIMS. As a results, the compressive strength assessing performance was compared. Since both systems assess concrete compressive strength with maturity method based on measured concrete temperature, both systems measured concrete temperature similarly, and maturity was calculated similarly. Therefore, the assumed compressive strength values were similar for both systems. Therefore, through the test, compressive strength assessing performance of CIMS was considered as a similar level of the 'G' company's system. Furthermore, it is considered that the CIMS has an additional advantage of reusability, adding capability of additional sensor, and wider range of Bluetooth communication.

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항우울제의 복약 순응도 (Treatment Compliance of Antidepressants)

  • 이문수;고영훈;조숙행
    • 생물정신의학
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    • 제17권1호
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    • pp.5-14
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    • 2010
  • Depressive disorder is a chronic disabling condition with recurrent episodes. Medication noncompliance is a significant problem for effective management of depressive disorder. However, compliance with antidepressant medication is poor. There are difficulties in assessing compliance accurately. Various methods for assessing compliance are in use. A patient's compliance with antidepressant may be affected by many factors including the clinical characteristics of depression, pharmacologic properties of antidepressants, patients' characteristics, accessibility treatment, and doctor-patient relationships. For enhancing the treatment compliance, psychotherapeutic considerations in patient-therapist relationship are needed.

고 위험 임신과 신생아 상태와의 관계에 관한 연구 (A Study of the Assessing the High Risk Mothers and Influencing to Their Newborn Babies)

  • 이경혜;이자형
    • 대한간호학회지
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    • 제9권2호
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    • pp.7-15
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    • 1979
  • This study was undertaken to determine .the identify the relation between the high risk mother and their baby which then allows the nurse to assess and plen for the delivery of optimal health care to the high risk groups. This study was carried out between January through December 1978. This study sample consisted of 300 pregnant women who visited Ewha womens hospital during this time. The method used to for the collection of data was an“Antepartum High-risk pregnancy scoring form. The questionair included 4 categories: 1) reproductives history 2) Associated conditions 3) pre-sent pregnancy and 4) total risk score . The bind are as follows: 1. The frequency of high risk pregnancy women 149(49.7%) was highest. 2. In the investigation sample high risk factors were related to hypertension and toremia. 3. There was a difference in the high risk scores and newborn babys scores (r = 0.610). 4. Relationship between high risk pregnancy women and least of pregnant women was highest prenatal mortality. Implications of positive assessing of high risk factors by MCH nurse and community health nurses.

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A Bayesian Meta Analysis for Assessing Bioequivalence among Two Generic Copies of the Same Brand-Name Drug

  • Oh, Hyun-Sook
    • Communications for Statistical Applications and Methods
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    • 제13권2호
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    • pp.285-295
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    • 2006
  • As more generic drugs become available, the quality, safety, and efficacy of generic drugs have become a public concern. Specifically, drug interchangeability among generic copies of the same brand-name drug is a safety concern. This research proposes a Bayesian method for assessing bioequivalence between two generic copies of the same brand-name drug from two independent $2{\times}2$ crossover design experiments. Uninformative priors are considered for general use and the posterior distribution of the difference of two generic drug effects is derived from which the highest probability density interval can be evaluated. Examples are presented for illustration.

원전의 부분충수운전에 대한 동적 신뢰도평가 (A New Method for Assessing Dynamic Reliability for the Mid-loop Operation)

  • 제무성;박군철
    • 한국안전학회지
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    • 제11권2호
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    • pp.52-59
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    • 1996
  • This paper presents a new approach for assessing the dynamic reliability in a complex system such as a nuclear power plant. The method is applied to a dynamic analysis of the potential accident sequences which may occur during mid-loop operation. Mid-loop operation is defined as an operation to make RCS water level below the top of the flow area of the hot legs at the junction with the reactor vessel for repairs and maintenance of steam generators and reactor coolant pumps for a specific time. The Idea behind this approach consists of both the use of the concept of the performance achievement/requirement correlation and of a dynamic event tree generation method. The assessment of the system reliability depends on the determination of both the required performance distribution and the achieved performance distribution. The quantified correlation between requirement and achievement represents a comparison between two competing variables. It is demonstrated that this method is easily applicable and flexible in that it can be applied to any kind of dynamic reliability problem.

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교통영향평가제도 개선방안 연구

  • 이한준;권영인;조준행
    • 대한교통학회지
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    • 제7권2호
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    • pp.71-87
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    • 1989
  • The objectives of this study are first, to evaluate the actual performance of the Transportation Impact Assesment System of Korea, second, to find the institutional problems of the system, and third, to seek for the best improvement of the system. Total 70 assessment reports performed in 1988 and judgements of the municipal councils of the reports were inspected. And the legal system of all levels were reviewed. According to the results, there are some needs to expand the number of cities subject to the assessment system. And the several regulations about the qualification of the agents assessing transportation impacts, the composition and operation of the municipal councils, and the timing of assessing the impacts are turned out improper. A proper alternative of amendment of the regulations are recommended. And the establishment of central council for judging assessments of hudge facilities, adoption of joint assessment of facilities bellow the standard, post occupancy assess ent, and transportation fee system were also recommended.

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Applying Gamification and Assessing its Effectiveness in a Tourism Context: Behavioural and Psychological Outcomes of the TripAdvisor's Gamification Users

  • Sigala, Marianna
    • Asia pacific journal of information systems
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    • 제25권1호
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    • pp.179-210
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    • 2015
  • Despite the increasing adoption of gamification and its huge potential in tourism, research in gamification is still limited. As preliminary findings show that the effectiveness of gamification depends on the context of its application and the players' use of the gamified app, this paper fills in these gaps: by exploring and analysing the application of gamification in a specific e-commerce tourism context; and assessing the gamification's effectiveness by measuring the players' gamification usage and the latter's behavioural and psychological outcomes. The gamified TripAdvisor website and its Facebook enabled gamification app are used as the specific context of the study. Findings from a survey conducted on TripAdvisor users provide useful practical and theoretical implications to gamification designers and researchers alike on how game mechanics can be designed for enhancing the users' motivation, flow, task involvement and engagement with the 'play' tasks, and so, increasing the gamification's effectiveness.

수완계 진동에 대한 인체 영향 평가 기법의 비교 분석 (Comparison and Analysis on the Assessment Methods of Human Effects of Hand-arm Vibration)

  • 정완섭;권휴상
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2001년도 추계학술대회논문집 II
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    • pp.1361-1364
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    • 2001
  • The recent national contract (Ecotechnopia 21) supported by the ministry of environment puts much significance on new issues for the assessment of human effects arising from vibration and noise exposed to human. This paper focuses only on hand-arm vibration since it has been a major problem in protecting vibration exposure to human. To set up a systematic way of assessing adverse effects of hand-arm vibration, surveys were made on recent international standards and researches related to hand-arm vibration. The measurement and evaluation methods of hand-arm transmitted vibration, the relationship between vibration exposure and effects on health, and the assessment methods of nerve dysfunctions are addressed in this paper. Those methods are linked into a logical way of assessing effects of hand-arm vibration on human. Finally, the current activities and achievements in this work are briefly summarised.

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인체 진동소음의 인체영향에 대한 국내외 기술조사 : 인체 진동 (investigation on Human Effects of Vibration and Noise Exposed on Human: I. Human Vibration)

  • 정완섭;권휴상
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2001년도 추계학술대회논문집 II
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    • pp.691-694
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    • 2001
  • The recent national contract (Ecotechnopia 21) supported by the ministry of environment puts much significance on new issues for the assessment of human effects arising from vibration and noise exposed to human. This paper focuses only on hand-arm vibration since it has been a major problem in protecting vibration exposure to human. To set up a systematic way of assessing adverse effects of hand-arm vibration, surveys were made on recent international standards and researches related to hand-arm vibration. The measurement and evaluation methods of hand-arm transmitted vibration, the relationship between vibration exposure and effects on health, and the assessment methods of nerve dysfunctions are addressed in this paper. Those methods are linked into a logical way of assessing effects of hand-arm vibration on human. Finally, the current activities and achievements in this work are briefly summarised.

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