• 대한두경부종양학회지
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• 제14권1호
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• pp.81-87
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• 1998

Fine needle aspiration cytology was used widely to select thyroid nodules for surgery. The result could be highly reliable for most malignancies and for benign nodules. The purpose of this study was to determine the value of frozen biopsy by directly comparing the results of preoperative fine needle aspiration cytology to frozen biopsy examination. In our university hospital, 103 patients with thyroid nodule were operated during the years 1996 through 1997. A comparison of accuracy of the fine needle aspiration cytology with frozen biopsy was made for 85 patients who underwent both procedures. The 85 patients were separated into two groups. The group I included 65 patients, whose preoperative fine needle aspiration cytology results were reported as benign or malignant lesion definitely. The group II included 85 patients, the patients whose reported fine needle aspiration cytologic result was suspicious for malignancy were regarded .as malignant lesion and results for follicular neoplasm were regarded as benign lesion. The accuracy of both procedures was compared on two group also. The sensitivity, specificity, and accuracy of frozen biopsy were 76.7%, 93.5%, and 85.2% in group I and 75.6%, 95.5%, and 85.9% in group II, respectively, compared with 63.3%, 87.1%, and 75.4% in group I and 65.4%, 81.8%, and 72.9% in group II for fine needle aspiration cytology. On benign lesion, the accuracy was 95.5% in frozen biopsy and 68.2% in fine needle aspiration cytology, 75.6% in frozen biopsy and 53.7% in fine needle aspiration cytology on malignant lesion. We conclude that although fine needle aspiration cytology is the reliable diagnostic test in the evaluation of thyroid nodule, frozen biopsy should be performed intraoperatively, because fine needle aspiration cytology is insufficiently sensitive for reliable surgical planning.

• Journal of Chest Surgery
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• 제26권4호
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• pp.329-332
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• 1993

Breakdown of the normal protective function of the larynx, either through primary or neurologic cause, leads to chronic aspiration, recurrent pneumonitis and possibly death. Lindemann`s tracheoesophageal diversion has three main advantages; first, it eliminates intractable aspiration in all patients who underwent the procedure, second, it preserves larynx, and third, if the underlying neurologic condition is recorved, the procedure can be reversed. We had performed tracheoesophageal diversion in two cases of intractable aspiration pneumonia patients. The postoperative courses were uneventful and they were receiving oral alimentation on the 22th and 9th postoperative days respectively, and could be discharged on 43th and 20th postoperative days respectively.

• Nuclear Medicine and Molecular Imaging
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• 제40권6호
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• pp.327-331
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• 2006

목적: 흡인 영상법은 흡인의 유무를 확인하고 흡인된 물질의 양을 정량화하기 위한 핵의학적 영상법이다. 본 연구의 최종 목적은 흡인 영상법으로 흡인과 흡인성 폐렴의 상관관계를 규명하는 것이고, 이 논문은 그 시도에 대한 예비적 보고이다. 대상 및 방법: 비디오투시연하검사에서 양성으로 확인된 10명의 환자들을 선택하였다 환자들이 Tc-99m tin colloid 92.5 MBq (2.5 mCi)을 넣은 반고형식을 먹은 직후 초기영상을 얻었고, 3시간 후에 지연영상을 얻었다. 식사한 양에 대한 흡인량의 비율인 흡인분율을 붕괴 보정을 이용한 방정식에 의하여 계산하였다. 결과: 5명의 환자들이 흡인 영상법에 의해 양성으로 판독되었다. 4명은 초기영상에서만 양성으로 판독되었고, 1명은 초기영상과 지연영상 모두에서 양성으로 판독되었다. 흡인분율은 0.11%, 0.11%, 0.81%, 그리고 0.11% 였다. 초기영상과 지연영상 모두에서 흡인된 환자의 흡인분율은 초기에 5.82%, 지연에 2.26% 였다. 결론: 흡인 영상법에 의해 시간의 경과에 따라 흡인의 위치를 확인할 수 있고 흡인된 물질의 양을 정량화 할 수 있다. 앞으로 환자에 대한 추적관찰이 필요하다.

• 말소리와 음성과학
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• 제9권4호
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• pp.9-17
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• 2017

The aim of this study is to examine whether Chinese Korean learners (CKL) can correctly produce the aspiration in 'a lenis obstruents /k/, /t/, /p/, /ʧ/+/h/ sound' sequence at the lexical and post-lexical level. For this purpose 4 Korean native speakers (KNS), 10 advanced and 10 intermediate CKL participated in a production test. The material analyzed consisted of 10 Korean sentences in which aspiration can be applied at different prosodic boundaries (syllable, word, accentual phrase). The results showed that for KNS and CKL, the rate of application of aspiration was different according to prosodic boundaries. Aspiration was more frequently applied at the lexical level than at the post-lexical level and it was more frequent at the word boundary than at the accentual phrase boundary. For CKL, pronunciation errors were either non-application of aspiration or coda obstruent omission. In the case of non-application of aspiration, CKL produced the target syllable as an underling form and they did not transform it as a surface form. In the case of coda obstruent ommision, most of the errors were caused by the inherent complexity of phonological process.

• 대한임상독성학회지
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• 제13권2호
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• pp.95-102
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• 2015

Purpose: Drug overdose is easily found in the emergency department (ED). Sedative-hypnotics overdose causes the aspiration pneumonia in patients with decreased mental status. The purpose of this study was to investigate the risk factors of aspiration pneumonia in patients poisoned with sedative-hypnotics. Methods: One hundred seventy eight patients who were poisoned with sedative-hypnotics and who visited ED between 2009 and 2015 were included. This study was conducted retrospectively, with collection of data by review of medical records. We collected the data concerning the characteristics of patients and classified them into two groups based on the development of aspiration pneumonia. Logistic regression analysis was performed to investigate the factors for the development of aspiration pneumonia. Results: Thirty five patients had an aspiration pneumonia during their hospital stay in 178 patients. The age, amount of ingestion, Glasgow Coma Scale (GCS) score at admission, a history of hypertension and diabetes mellitus, and the hypotension at admission were significantly different between two groups in univariate analysis. The age, amount of ingestion and GCS score at admission were associated with the development of aspiration pneumonia in the multivariate logistic regression analysis (OR 1.028 (95%CI, 1.002-1.056, p=0.037), 1.026 (95%CI, 1.004-1.043, p=0.001), 0.737 (95%CI, 0.683-0.915, p=0.002)). All patients with aspiration pneumonia were discharged without a sequelae. Conclusion: The development of aspiration pneumonia in the patients of sedative-hypnotics overdose is associated with old age, amount of drug ingestion, and GCS score at admission.

• 한국수정란이식학회지
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• 제12권1호
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• pp.111-116
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• 1997

The present study was carried out to produce in vitro fertilized embryos with immature follicular oocytes collected by transvaginal aspiration from Holstein cows. A simple aspiration apparatus consists of two stainless steel tubes, an inner tube (needle holder; 1.2cmdiameter, 55cm long) and an outer tube (1.5cm diameter, 4Scm long), and a hand-operated vacuum pump was used. Under epidural anesthesia, the needle guide was passed into the vagina of the cow to a point next to the cervix. An ovary was placed against the wall of the vagina over the end of the aspiration needle by rectal manipulation. As the needlepassed into the ovary, an assistant was asked to apply vacuum(l00mrnHg) and the ovary was manipulated back and forth in all directions over the needle. When all sites of the ovary was aspirated, the needle was withdrawn and the needle guide was moved to the other side of ovary and the procedure was repeated. When the oocyte aspiration procedure was finished, collected fluid was transported to laboratory. Oocytes surrounded with at least 1 layer of cumulus cells were matured, fertilized and cultured in vitro. The results were as follows; Ninety seven oocytes were collected by transvaginal aspiration from seventeen Holstein cows(5.7 /head). The number of oocytes surrounded with at least 1 layer of cumulus cells were 60(61.9%). Following in vitro maturation, fertilization and culture, the cleavage and development rate to morula+blastocyst were 83.3% and 30.0%, respectively. From this study, transferable in vitro fertilized embryos could be produced with imma- ture follicular oocytes collected by transvaginal aspiration from Holstein cows using a simple aspiration apparatus.

• 초등상담연구
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• 제10권1호
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• pp.95-108
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• 2011

이 연구는 초등학생의 직업포부를 형성하는 과정에 영향을 주는 요인들을 살펴 이에 대한 경험적 자료를 마련하는데 그 목적이 있다. 이러한 목적에 따라 초등학생의 개인적 특성 변인 중에서도 인지적 측면인 학업성취와 정의적 측면인 자아존중감, 환경적 측면인 부모의 학력을 변인으로 정하여 직업포부 수준과 어떤 관계가 있는지 연구문제를 설정하였다. 이 연구결과 성별에 따른 직업포부 수준은 여학생이 남학생보다 높게 나타났으며, 학년에 따라서는 통계적으로 유의미한 차이를 보이지 않았다. 그리고 초등학생의 학업성취는 직업포부 수준과정적인 상관관계를 보였으며, 자아존중감과 직업포부 수준의 관계는 통계적으로 유의하지 않았다. 학업성취와 자아존중감을 예측변인으로 했을 때 4학년의 경우에는 직업포부 수준의 9%, 6학년은 12%를 설명하였고, 부모의 학력에 따른 초등학생의 직업포부 수준은 통계적으로 유의미한 차이를 보이지 않았다. 특히 초등학생 4, 6학년이 직업의 특성뿐만 아니라 학업성취, 즉 자신의 능력을 함께 고려하여 직업포부를 결정한다는 것을 알 수 있었다.

• Reproductive and Developmental Biology
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• 제30권3호
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• pp.207-212
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• 2006

본 연구는 물리적 탈핵 방법인 aspiration 방법과 squeezing 방법을 사용해 핵이식된 소 체세포 복제란의 발달능을 조사하였다. 두 방법에 의해 탈핵된 수핵란에 한우 귀피부 세포를 융합하여 체외에서 $7{\sim}8$일간 배양하여 발육능을 검사하였다. 배양 7일째 배반포 발달율은 aspiration 방법($31.9{\pm}13.4%$)과 squeezing 방법($33.6{\pm}15.7%$) 간에 차이가 없었다. 또한 배양 8일째 배반포 발달율도 squeezing 방법($35.3{\pm}15.1%$)과 aspiration 방법($37.8{\pm}10.4%$) 간에 차이가 없는 것으로 나타났다. 배양 7일째 배반포의 평균 세포수에 있어 각 처리 간에 차이가 없는 것으로 조사되었으며(aspiration: $110.3{\pm}39.2$, squeezing $103.7{\pm}42.8$), 세포자연사의 비율에 있어서도 역시 유의적인 차이가 없는 것으로 조사되었다(aspiration: $2.8{\pm}2.6%$, squeezing: $4.3{\pm}4.4%$). 본 연구의 결과는 물리적 탈핵 방법인 aspiration 방법과 squeezing 방법 모두 소 체세포 복제수정란의 생산을 위한 유용한 방법임을 보여준다.

• 대한기관식도과학회지
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• 제7권2호
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• pp.140-145
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• 2001

Background and Objectives： Intractable aspiration in patients with impaired protective function of the larynx often results in multiple episode of aspiration pneumonia, repeated hospitalizations and expensive nursing care. The purpose of this study was to review the authors’experience and Patient outcome with the laryngotracheal separation (LTS) procedure. Materials and Methods A retrospective review of 9 patients who underwent LTS between 1996 and 2001 was conducted. Ages ranged from 3 to 72 years. Results : Seven patients were expected to have morbid aspiration as a consequence of acquired neurologic injuries and two were congenital neurologic injuries. Two patients had a postoperative fistula, which was well controlled with local wound care and minor procedure. Following LTS, aspiration was effectively controlled in all patients and four were able to tolerate a regular diet. Conclusion : LTS is a low-risk, successful. definitive procedure which decreases the potential for aspiration, pulmonary complication, hospitalizations and increases quality of life, especially in patent with irreversible upper airway dysfunction and Poor speech potential.

• Journal of Yeungnam Medical Science
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• 제21권1호
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• pp.127-131
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• 2004

A laryngeal mask airway (LMA) has many advantages in the management of airway emergencies or the treatment of patients in whom intubation is difficult, but the use of LMA during positive ventilation may seem inappropriate to protect the airway because of the risk of pulmonary aspiration of regurgitated gastric contents. We experienced aspiration pneumonia after general anesthesia using LMA in patient who suffered from panperitonitis. It is considered that the main reason for aspiration pneumonia was a leakage of gastric content through the space surrounding the nasogastric tube while under high airway inflation pressure. We concluded that when LMA or the Proseal laryngeal mask airway (PLMA) is chosen for the use in difficult intubations, careful patient-suitability selection and the correct knowledge of LMA and PLMA are needed to protect the airway against aspiration.