• Title/Summary/Keyword: Arylethanolamine

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Synthesis of Tetrahydrocarbazole Derivatives as Potent β3-Adrenoceptor Agonists

  • Ha, Jae-Du;Kang, Seung-Kyu;Cheon, Hyae-Gyeong;Choi, Joong-Kwon
    • Bulletin of the Korean Chemical Society
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    • v.25 no.12
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    • pp.1784-1790
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    • 2004
  • A series of 2-(3-chlorophenyl)-2-hydroxyethylamine derivatives containing a tetrahydrocarbazole linker were prepared and evaluated for their ${\beta}_3$-adrenoceptor agonistic activity. Several compounds showed potency comparable to CL-316243.