• Title/Summary/Keyword: Artificial skin

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The Effectiveness of Electroglottographic Parameters in Differential Diagnosis of Laryngeal Cancer (후두암 감별진단에 있어 성문전도(Electroglottograph) 파라미터의 유용성)

  • 송인무;고의경;전경명;권순복;김기련;전계록;김광년;정동근;조철우
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.14 no.1
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    • pp.16-25
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    • 2003
  • Background and Objectives : Electroglottography(EGG) is a non-invasive method of monitoring the vocal cord vibration by measuring the variation of physiological impedance across the vocal folds through the neck skin. It reveals especially the vocal fold contact area and is widely used for basic laryngeal researches, voice analysis and synthesis. The purpose of this study is to investigate the effectiveness of EGG parameters in differential diagnosis of laryngeal cancer. Materials and Methods : The author investigated 10 laryngeal cancer and 25 benign laryngeal disease patients who visited at the Department of Otolaryngology, Pusan National University Hospital. The EGG equipment was devised in the author's Department. Among various parameters of EGG, closed quotient(CQ), speed quotient(SQ), speed index(SI), Jitter, Shimmer, Fo were determined by an analysis program made with MATLAB 6.5$^{\circledR}$(Mathwork, Inc.). In order to differentiate various laryngeal diseases from pathologic voice signals, the author has used the electroglottographic parameters using the neural network of multilayer perceptron structure. Results : SQ, SI, Jitter and Shimmer values except those of CQ and Fo showed remarkable differences between benign and malignant laryngeal disease groups. From the artificial neural network, the percentage of differentiating the laryngeal cancer was over 80% in SQ, SI, Jitter, Shimmer except for CQ and Fo. These results indicated that it is possible to discriminate the benign and malignant laryngeal diseases by EGG parameters using the artificial neural network. Conclusion : If parameters of EGG which can reveal for the pathology of laryngeal diseases are additionally developed and the current classification algorithm is improved, the discrimination of laryngeal cancer will become much more accurate.

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Analysis of Reinforcement Effect of Hollow Modular Concrete Block on Sand by Laboratory Model Tests (실내모형실험을 통한 모래지반에서의 중공블록 보강효과 분석)

  • Lee, Chul-Hee;Shin, Eun-Chul;Yang, Tae-Chul
    • Journal of the Korean Geotechnical Society
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    • v.38 no.7
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    • pp.49-62
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    • 2022
  • The hollow modular concrete block reinforced foundation method is one of the ground reinforcement foundation methods that uses hexagonal honeycomb-shaped concrete blocks with mixed crushed rock to reinforce soft grounds. It then forms an artificial layered ground that increases bearing capacity and reduces settlement. The hollow modular honeycomb-shaped concrete block is a geometrically economical, stable structure that distributes forces in a balanced way. However, the behavioral characteristics of hollow modular concrete block reinforced foundations are not yet fully understood. In this study, a bearing capacity test is performed to analyze the reinforcement effectiveness of the hollow modular concrete block through the laboratory model tests. From the load-settlement curve, punching shear failure occurs under the unfilled sand condition (A-1-N). However, the filled sand condition (A-1-F) shows a linear curve without yielding, confirming the reinforcement effect is three times higher than that of unreinforced ground. The bearing capacity equation is proposed for the parts that have contact pressure under concrete, vertical stress of hollow blocks, and the inner skin friction force from horizontal stress by confining effect based on the schematic diagram of confining effect inside a hollow modular concrete block. As a result of calculating the bearing capacity, the percentage of load distribution for contact force on the area of concrete is about 65%, vertical force on the area of hollow is 16.5% and inner skin friction force of area of the inner wall is about 18.5%. When the surcharge load is applied to the concrete part, the vertical stress occurs on the area of the hollow part by confining effect first. Then, in the filled sand in the hollow where the horizontal direction is constrained, the inner skin friction force occurs by the horizontal stress on the inner wall of the hollow modular concrete block. The inner skin friction force suppresses the punching of the concrete part and reduces contact pressure.

A Study of the Stability and Moisturizing Effect of Non-Animal Cholesteric Liquid Crystal (비동물성 콜레스테릭 액정의 안정성과 보습효능에 관한 연구)

  • Woo, Byoung Young;Min, Dae Jin;Baek, Heung Soo;Kim, Shin Hyoung;Hwang, Joon Young;Park, Young Ho;Lee, John Hwan;Shin, Song Seok
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.40 no.2
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    • pp.141-153
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    • 2014
  • This study is about the development of cholesteric liquid crystals (CLCs), which are highly applicable to cosmetics formulation. The CLCs made from non-animal origin were chosen not only because they are free of animal viruses but also because they give a sense of security to the cosmetic consumers. Three kinds of new cholesteric derivatives (CI, CC, CN) were synthesized using non-animal cholesterol [NAB cholesterol (ARCH LONZA)], which was originally made by fermentation process. To develop high applicability to cosmetics formulation, we attempted to find out the optimum compositions in which CLCs can maintain their color over a wide range of temperature. The CLCs in 41 different compositions were prepared by the combinations of three cholesteric derivatives and a visual evaluation method was employed to determine the range of temperature at which the CLCs display their color. The 205 UV-VIS spectral data obtained from 41 CLCs at various temperatures were simultaneously analyzed to investigate the critical factors affecting the characteristics of the CLCs. Results showed that A4, A5, A6 and A7 were the best compositions to cosmetics formulation. A6 composition had a great moisturizing effect by the artificial skin test ($AmoReSkin^{TM}$).

Comparison Study on the Make-up Cultures between the Ching dynasty in China and the Edo Age in Japan based on their Aesthetic Consciousness (중국(中國) 청(淸) 왕조시대(王朝時代)와 일본(日本) 강호시대(江戶時代)의 미의식(美意識)에 따른 화장문화(化粧文化) 비교 연구)

  • Ahn, Hyun-soon;Koh, Jung-min
    • Cross-Cultural Studies
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    • v.27
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    • pp.59-79
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    • 2012
  • China and Japan are geographically close and the two countries had shared the Chinese Character Culture and the thoughts of Confucianism, Buddhism and Taoism since the ancient age. They also actively exchanged culture in various areas. Some cultural exchanges had been caused by surrounding environment and culture had been introduced to other country in a natural way; while some cultural exchanges had been forcibly introduced through artificial process. It is believed that such cultural phenomenon must have had impact on the make-up cultures of the two countries and it was assumed that there must have been commons and differences in the make-up cultures of the two countries. This study explored the historical background of the Ching dynasty of China and the Edo Age in Japan, which are in the same time frame, and studied the aesthetic consciousness of the two countries at the time. Then the make-up style of ladies in the two countries had been studied to find out how their aesthetic consciousnesses had been expressed in the make-ups of the two countries. Then the commons and differences in make-up skills between the two countries had been identified. According to the study results, the main stream of aesthetics during the Ching dynasty in China can be classified into Confucianism aesthetics and Taoism aesthetics. On the other hand, the main stream of aesthetics during the Edo Age in Japan can be classified into "mitate(見立)", "ikki(いき)" and "garumi(かるみ). The skin care in the make-up culture of Ching dynasty in China was based on "rouge (?脂, yanzhi)" and "powder(粉, fen)". The Ching ladies loved the make-up style using rouge. It had been same both in the high society and common people. The eyebrow care was delicate and curved so that the feminine beauty with elegant spirit could be emphasized. The lips had been expressed to be smaller and the ladies tried to express elegance and reliability, rather than frail and tender feminine image. The skin care in the make-up culture of Edo Age in Japan focused on even applying of white powder so that the face would look soft. The eyebrow make-up was a very important part of the make-up. The shapes of eyebrow had been advanced in various styles and there had been eyebrow make-up styles such as "crescent-shaped brow (三日月), "crane style brow (鶴眉) and "Tang style brow (唐眉). The lips had been applied of thick red color, imitating the make-up skill of the ladies in the entertainment business. The lips make-up skill expressing the lips in two colors had been quite popular. Among the make-up skills during the Edo Age in Japan, the "black teeth (齒黑)" can be said as the most unique make-up style of Edo Age.

Whitening Effects of Angelica dahurica Radix Ethanol Extract (백지 에탄올추출물의 미백효능 연구)

  • Kim, Pil-Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.9
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    • pp.4038-4045
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    • 2011
  • To investigate whitening Effects of Angelica dahurica Radix Ethanol Extract (ADEE), we used melan-a cell line, brown guinea pig, and HMB-45. We treated with ADEE of 6.25, 12.5, 25, and 50 ${\mu}g/m{\ell}$ concentration in order to evaluate the effect of ADEE on cell viability and on morphological observation of melan-a cells. Also we were induced the artificial tanning spots by 1,500 mJ/$cm^2$ of ultraviolet B radiation on the backs of brown guinea pigs (approximately 450~500g) and then the test agent of $30{\mu}{\ell}$ was applied on the spots twice a day, five days a week, for five weeks respectively. The visible whitening effect was evaluated once a week. At the end of the experiment, the animals were sacrificed under anesthetization. The artificial tanning spots were obtained by biopsy punch and stained with HMB-45 to observe the gp100 proteins which were melanosomes. Our results show that cell viability was not reduce at ADEE concentrations between 6.25 and 50 ${\mu}g/m{\ell}$, melanin synthesis and melanocyte dendricity were decreased in ADEE treated melan-a cells increasing ADEE concentration. In the gross observation, ADEE treated groups had lower pigmentation than the vehicle control groups. And in the histological observation, ADEE treated groups had lower melanocytes than the vehicle control groups. Also in the quantitative analysis of the gp100 proteins using image analysis software, ADEE treated groups had a significantly lower value (p<0.001) than the vehicle control group and this resultsagreed with the results of observation under microscope. From these results, weconcluded that ADEE had positive whitening effect.

Scab (Venturia nashicola) Resistant Pear, "Wonkyo Na-heukseong 2" (배 검은별무늬병 저항성 "원교 나-흑성 2호")

  • Shin, Il-Sheob;Hwang, Hae-Sung;Shin, Yong-Uk;Heo, Seong;Kim, Ki-Hong;Kang, Sam-Seok;Kim, Yoon-Kyeong
    • Korean Journal of Breeding Science
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    • v.41 no.3
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    • pp.354-357
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    • 2009
  • "Wonkyo Na-heukseong 2" was selected from a cross between "Kiyomaro", late season European cultivar with highly resistance and "Mansoo", late season Asian cultivar with long storability, large size and low susceptibility to pear scab made in 1997 at the National Institute of Horticultural & Herbal Science of Rural Development Administration in Korea. "Kiyomaro", released cross between "Taiheiyo" and "Bartlett" with scab resistance caused by Venturia nashicola in Japan, with no visual symptoms on any leaves was used as scab resistant source after field investigation and artificial inoculation test during 1997~1999. "Wonkyo Na-heukseong 2" blooms 1 day earlier than "Mansoo" and 3 days later than "Kiyomaro" in 2008. It is strong in tree vigor and upright-spreading in tree habit. It is classified as highly resistant to pear scab as "Kiyomaro" and "Bartlett", and cross-compatible with parental variety and Korean major pear varieties such as "Niitaka" and "Wonwhang". The average optimum harvest time of "Wonkyo Na-heukseong 2" was approximately 180 days after full bloom and it matured about 20 days shorter than parental varieties. The fruit is spindle in shape and yellowish greenish brown in skin color. Average fruit weight was 484 g and soluble solids content was $13.2^{\circ}Brix$. The flesh had medium to high juice and negligible grit. Its fruit was crisp like Asian pear.

Design and SAR Analysis of Wearable Antenna on Various Parts of Human Body, Using Conventional and Artificial Ground Planes

  • Ali, Usman;Ullah, Sadiq;Khan, Jalal;Shafi, Muhammad;Kamal, Babar;Basir, Abdul;Flint, James A;Seager, Rob D.
    • Journal of Electrical Engineering and Technology
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    • v.12 no.1
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    • pp.317-328
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    • 2017
  • This paper presents design and specific absorption rate analysis of a 2.4 GHz wearable patch antenna on a conventional and electromagnetic bandgap (EBG) ground planes, under normal and bent conditions. Wearable materials are used in the design of the antenna and EBG surfaces. A woven fabric (Zelt) is used as a conductive material and a 3 mm thicker Wash Cotton is used as a substrate. The dielectric constant and tangent loss of the substrate are 1.51 and 0.02 respectively. The volume of the proposed antenna is $113{\times}96.4{\times}3mm^3$. The metamaterial surface is used as a high impedance surface which shields the body from the hazards of electromagnetic radiations to reduce the Specific Absorption Rate (SAR). For on-body analysis a three layer model (containing skin, fats and muscles) of human arm is used. Antenna employing the EBG ground plane gives safe value of SAR (i.e. 1.77W/kg<2W/kg), when worn on human arm. This value is obtained using the safe limit of 2 W/kg, averaged over 10g of tissue, specified by the International Commission of Non Ionization Radiation Protection (ICNIRP). The SAR is reduced by 83.82 % as compare to the conventional antenna (8.16 W/kg>2W/kg). The efficiency of the EBG based antenna is improved from 52 to 74 %, relative to the conventional counterpart. The proposed antenna can be used in wearable electronics and smart clothing.

Inhibitory effect of glyceollin isolated from soybean against melanogenesis in B16 melanoma cells

  • Lee, Young-Sang;Kim, Hyun-Kyoung;Lee, Kyung-Ju;Jeon, Hye-Won;Cui, Song;Lee, You-Mie;Moon, Byung-Jo;Kim, Yong-Hoon;Lee, Young-Sup
    • BMB Reports
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    • v.43 no.7
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    • pp.461-467
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    • 2010
  • Natural products with non-toxic and environmentally friendly properties are good resources for skin-whitening cosmetic agents when compared to artificial synthetic chemicals. Here, we investigated the effect of glyceollin produced to induce disease resistance responses of soybean to specific races of an incompatible pathogen, phytophthora sojae, on melanogenesis and discussed their mechanisms in melanin biosynthesis. We found that glyceollin inhibits melanin synthesis and tyrosinase activity in B16 melanoma cells without cytotoxicity. To elucidate the mechanism of the effect of glyceollin on melanogenesis, we conducted western blot analysis for melanogenic enzymes such as tyrosinase, tyrosinase-related protein-1 (TRP-1), and TRP-2. Glyceollin inhibited tyrosinase and TRP-1 protein expression. Additionally, glyceollin effectively inhibited intracellular cAMP levels in B16 melanoma cells stimulated by $\alpha$-melanocyte stimulating hormone ($\alpha$-MSH). These results suggest that the whitening activity of glyceollin may be due to the inhibition of cAMP involved in the signal pathway of $\alpha$-MSH in B16 melanoma cells.

Characteristics of BGsome-Coated Illite as a Face Powder (BGsome이 코팅된 일라이트 및 이를 함유한 페이스 파우더의 특성)

  • Lim, Jin Kyong;Jin, Byung Suk
    • Applied Chemistry for Engineering
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    • v.24 no.2
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    • pp.126-131
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    • 2013
  • BGsome coating on the surface of illite powder was attempted to impart skin affinity and improve various characteristics of the powder for makeup cosmetics. BGsome is a type of hydrated liquid crystalline vesicles prepared by the hydration of 1,3-butylene glycol (BG) dissolved lecithin. BGsome droplets were coated through wet process and the coated powders were analyzed by TGA, SEM, and particle size measurements. Effect of BGsome coating on the physical properties, such as flow-ability, dispersibility, spreadability, and adhesion, were examined. The repose angle of BGsome-coated illite was decreased, which means that BGsome coating improves the flowability of the powder. Dispersibility, spreadability, and adhesion of the coated illite were also improved remarkably. The result of adhesion tests showed that the BGsome-coated illite was evenly adhered onto artificial leather surface with almost no lumps. The flowability, dispersibility, spreadability and adhesion of face powders containing the BGsome-coated illite were also improved.

Fusarium Fruit Rot of Posthavest Oriental Melon (Cucumis melo L. var. makuwa Mak.) Caused by Fusarium spp. (Fusarium spp.에 의한 수확 후 참외 열매썩음병)

  • Kim, Jin-Won;Kim, Hyun-Jin
    • Research in Plant Disease
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    • v.10 no.4
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    • pp.260-267
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    • 2004
  • Fusarium spp. were isolated from the postharvest fruit rot of oriental melon fruits at commercial fruit markets in Korea during 2001 to 2003. The decayed fruits were covered with the fungal mycelia and eventually soft rotted. The disease started at the fruit stalk area, the calyx end of the fruit and skin of fruit. As the disease advanced, white to pinkish mycelia covered with the surface of decayed fruit. The cultural and morphological characteristic of Fusarium spp. were compared with descriptions of those reported previously, and identified as Fusarium equiseti, F. graminearum, F. moniliforme, F. proliferatum, F. sambucinum, and F. semitectum. Pathogenicity of the isolates was proved by artificial wound and unwound inoculation onto the healthy fruits. Two days after inoculation, aerial mycelia were noticed on the wound inocultion region of the fruit and developed soft rot symptoms. Although Fusarium spp. causing fruit rot disease in oriental melon have been reported in Korea, identification of the those species was not described. Therefore, this is the first report of Fusarium spp. causing postharvest fruit rot on oriental melon in Korea.