• Title/Summary/Keyword: Artificial organs

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Proximate Composition of Viscera of Major, Common and Some Chinese Carps Under the Effect of Different Fertilization Schemes and Feed Supplementation in Composite Culture System

  • Mahboob, Shahid;Sheri, A.N.
    • Asian-Australasian Journal of Animal Sciences
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    • v.11 no.2
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    • pp.196-200
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    • 1998
  • The proximate composition of viscera of six fish species viz., Catla catla, Labeo, rohita Cirrhina mrigala, Hypophthalmichthys molitrix, Ctenopharyngodon idella and Cyprinus carpio under the influence of artificial feed $(T_1)$, broiler manure $(T_2)$, buffalo manure $(T_3)$, N:P:K (25:25:0 $T_4$) and control pond $(T_5)$ has been studied on final harvest after the end of experimental period of one year. The overall comparison of six fish species under five different treatments showed that Cyprinus carpio remained the best for visceral total protein contents. The maximum visceral protein content was recorded in fishes under $T_2$ except Cirrhina mrigala, while the minimum under $T_5$. The comparison of five treatments showed that maximum (6.69) percentage of fat in viscera of fish was recorded under $T_2$, closely followed by $T_4$ while minimum (4.89) under the effect of $T_5$. Among the six fish species under five treatments Cyprinus carpio showed maximum accumulation/deposition of total fats in viscera.

Sonogram of coccygeus muscle in dairy cows with different gestational ages

  • Ulum, Mokhamad Fakhrul;Frastantie, Dilla;Purwantara, Bambang
    • Journal of Animal Science and Technology
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    • v.59 no.12
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    • pp.26.1-26.8
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    • 2017
  • Background: The change in size and weight of the female reproductive organs during gestation and birth might be affect the perineal muscles and this condition in dairy cow not been reported. This study aimed to assess the ultrasonographic image of coccygeus muscle in 11 inseminated dairy cows with different gestational ages and postpartum. Methods: Gestational age was calculated based on the record of artificial insemination and confirmed by using transrectal brightness mode ultrasonography. Perineal hair between the sacrum and ischium bones was shaved along 3-5 cm before being ultrasound. The images of perineal area were obtained by transcutaneous ultrasound using a 5.0 MHz transducer. The thickness and intensity of the coccygeus muscle were measured and analyzed by gestational status and postpartum to show the differences. Results: The results showed that the thickness of coccygeus muscle increased with the increase in gestational age. Muscle intensity only increased at young gestational age. However, it decreased with the increase in gestational age (P < 0.05). Conclusions: The ultrasound image of coccygeus muscle was affected by gestational status, thus this method may be used as one of the new methods of indirect gestational detection on dairy cows.

Status and Prospect of 3D Bio-Printing Technology (3D 바이오 프린팅 기술 현황과 응용)

  • Kim, Sung Ho;Yeo, Ki Baek;Park, Min Kyu;Park, Joung Soon;Ki, Mi Ran;Pack, Seung Pil
    • KSBB Journal
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    • v.30 no.6
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    • pp.268-274
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    • 2015
  • 3D printing technology has been used in various fields such as materials science, manufacturing, education, and medical field. A number of research are underway to improve the 3D printing technology. Recently, the use of 3D printing technology for fabricating an artificial tissue, organ and bone through the laminating of cell and biocompatible material has been introduced and this could make the conformity with the desired shape or pattern for producing human entire organs for transplantation. This special printing technique is known as "3D Bio-Printing", which has potential in biomedical application including patient-customized organ out-put. In this paper, we describe the current 3D bio-printing technology, and bio-materials used in it and present it's practical applications.

Phenotype of Hepartocyte Spheroids in Synthetic Thermo-reversible Extracellular Matrix

  • Park, Keun--Hong;Park, Ju-Young;Bae, You-Han
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.6 no.4
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    • pp.264-268
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    • 2001
  • Aggregates of specific cells are often regarded as better from in artificial organs and mammalian cell bioreactors in terms of cell-specific functionality. In this study, the morphology and liver specific functions of freshly harvested primary rat hepatocytes, which were cultivated as spheroids and entrapped in a synthetic thermo-reversible extracellular matrix, were examined and compared to a control (hepatocytes in single cell form). A copolymer of N-isopropylacrylamide(98 mole % in feed) and acrylic acid (poly (NiPAAm-co-AAC)), a thermo- reversible copolymer gel ma- trix, was used to entrap hepatocytes either in spheroids or single cells. During a 7-day culture pe-riod, the spheroids maintained higher viability and produced albumin and urea at a relatively con-stant rate, while, the single cell culture showed a slight increase in cell numbers and a reduction in albumin secretion Hepatocytes cultrured as spheroids present a potentially useful three-dimensional cell culture system for application in bioartificial liver device.

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A Study of Heavy Metal Contents in plants from Mt. Kwang-Duk Area (광덕산 식물체의 중금속 함량에 관한 연구)

  • 이기태;최한수
    • Environmental Analysis Health and Toxicology
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    • v.14 no.4
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    • pp.155-163
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    • 1999
  • Heavy metal accumulation in living organisms through food-wed can give serious damage on physiological responses for vital activities. The initiation of heavy metal supposed to begin from the bio-accumulation of plants. To establish basic data fur heavy metal contents in plants at the area without artificial contamination, both woody and herb plants at Mt. Kwang-Duk were studied. The content of heavy metals in various organs of plants were analyzed by ICP. The range of heavy metals in plants for Al, As, Cd, Co, Cr, Cu, Fe. Mn, Pb, Se and Zn were 1.019∼257.200ppm, O∼2.929ppm, 0∼0.079ppm, 0∼0.054ppm, 0.023∼3.007ppm, 0∼1.997ppm, 2.031∼148.500ppm, 1.069∼51.320ppm, O∼126.900ppm, 0.708∼4.927ppm and 0.846∼4.949ppm, respectively. The amount of heavy metals in plants are much less than that of soil except some species. In woody plants, it was detected that the metal contents of leaves were higher than that of stems especially in case of Al and Fe with statistical significance. There were significant differences between shoots and roots of herb plants in metal content of Al, Co and Fe. Those metals have more accumulated in roots comparing with shoots. Some species of plants had shown the difference tendency of heavy metal accumulation. Generally, most species had not exceeded over twice of mean value each other, and had various difference according to the kinds of heavy metals.

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Mechanical Behaviour of Non-Oxide Boride Type Ceramics Formed on The AISI 1040 Plain Carbon Steel

  • Sen, Saduman;Usta, Metin;Bindal, Cuma;UciSik, A.Hikmet
    • The Korean Journal of Ceramics
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    • v.6 no.1
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    • pp.27-31
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    • 2000
  • A series experiments were performed to evaluate mechanical behavior of non-oxide boride type ceramics formed on the AISI 1040 plain carbon steel. Boronizing was performed in a slurry salt bath consisting of borax, boric acid, and ferro-silicon at $950^{\circ}C$ for 2-6h. The AISI 1040 steel used as substrate material was containing 0.4%C, 0.13%Si, 0.65%Mn, 0.02%P, 0.014%S. The presence of non-oxide boride type ceramics $Fe_2B $ and FeB formed on the surface of steel was confirmed by metallographic technique and X-ray diffraction (XRD) analysis. The hardness of borides measured via Vickers indenter with a load of 2N reached a microhardness of up to 1800 DPN. The hardness of unborided steel was 185 DPN. The fracture toughness of borides measured by means of Vickers indenter with a load of 10N was about 2.30 MPa.$m^{1/2}$. The thickness of boride layers ranged from 72$\mu\textrm{m}$ to 145$\mu\textrm{m}$. Boride layers have a columnar morphology.

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Review of Experimental Tracheal Reconstruction (실험적 기관 재건술에 대한 고찰)

  • 성숙환;김용희
    • Korean Journal of Bronchoesophagology
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    • v.7 no.2
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    • pp.128-139
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    • 2001
  • The purpose of this study was to review the literatures of experimental tracheal reconstruction. Although there have been significant advancements in the surgical treatment of the long circumferential tracheal injuries, there still has been a difficult problem with high morbidity and mortality. The method for tracheal reconstruction after circumferential resection is preferred end-to-end anastomosis for defects up to 6 cm in length, but larger tracheal defects require the use of tracheal allograft, various artificial prosthesis or autogenous organs. The tracheal allotransplantation has been widely used as there was significantly improved the method of surgical technique, preservation and immunosuppression. But it has been limited by a number of factors such as few donor, limited use of immunosuppressant, delayed revascularization and re-epitheliazation. Experimental studies on the tracheal prosthesis have a long history and they tried to use silicone, polytetrafluoroethylene, polypropylene mesh, Dacron, Marlex mesh, external or internal stents. Other experimental studies were reported the use of autogenous tissues that were cartilage. jejunum, aorta, skin, muscle, periostium or esophagus. But a great variety of these protheses have been resulted unsatisfactory in a significant Proportion of cases. Alternatively, the tissue-engineering technique has showed a new approach to reconstruct trachea and much progress in tissue-engineering bas been made recently. In conclusion, although the tracheal allotransplantation and the use of prosthesis and allograft have been reported a lot of limitation to overcome, we could sooner expect good result of ideal tracheal prosthesis.

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TAH(Total Artificial Heart) Virtual Surgery Using Multi-Volume Visualizing Technique (다중 체적 가시 기법을 이용한 완전인공심장의 가상 수술)

  • Lee, D.H.;Kim, J.H.;Kim, N.K.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.11
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    • pp.587-589
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    • 1997
  • The virtual surgical trial of TAH is very important in some points as follows. The chests of patients who is under heart-disease are various types of undefine form. It is hard to say that there exist the standard shape of TAH and the position to surgern. So, the virtual surgery system is very important in realizing TAH surgery of human. We have implemented virtual surgery system of TAH that supporting multi volume fitting trial. We have acquired CT images of patients with DICOM format. Each organ of patients was segmented in 2-dimensional CT images. 3-dimensional objects were made with marching cube algorithm and save as file in VRML format. Virtual fitting trial was performed on Cosmo-World; a VRML editor. The collision points of TAH with other organs were well observed. And the best position and angles were determined and saved or each case. We believed that this virtual surgery will be helpful in TAH surgery and TAH customizing.

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Treatment of Chronic Wound in a Patient with Systemic Vasculitis (전신성 혈관염 환자의 족부 만성 창상의 치험례)

  • Lim, Jin Soo;Kim, Hyung Jun;Joo, Hong Sil;Choi, Yun Seok
    • Archives of Plastic Surgery
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    • v.33 no.1
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    • pp.116-119
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    • 2006
  • Management of chronic wound has been a great problem to many surgeons because the wound is usually associated with an underlying disease of the patient. Without accurate diagnosis and treatment of the disease, the wound can not be healed. Systemic vasculitis is a rare systemic disease which causes inflammation and obstruction of the vessels. This autoimmune disease involves multiple organs and may inflict skin wound spontaneously without traumas. It would improve or aggravate the wound in proportion to the activities of the disease. Our experience is a case of 28-year-old female who has had chronic ulcers on her right foot, especially on the great toe for 1 year. Although she had several operations of sympathectomy, debridement and artificial dermal graft, her wound was not improved. She has been diagnosed as systemic vasculitis during the evaluation for histopathology and cause of fever and pancytopenia. After medical treatments, she had the operation of adipofascial turnover flap coverage and skin graft, and the wound was improved without any complication or relapse. The diagnosis and treatment of the underlying disease should be ahead of the management of chronic wound.

In Vivo Blood Compatibility of PU-PEO-SO3 as Coating Material for Blood Sac of Left Ventricular Assist Device ( LVAD) (좌심실보조장치의 혈액주머니용 코팅재료로서 PU-PEO-SO3의 in vivo 혈액적합성에 관한 연구)

  • 한동근;김종원
    • Journal of Biomedical Engineering Research
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    • v.15 no.1
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    • pp.19-26
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    • 1994
  • Sulfonated poly (ethyleneoxide)-grafted polyurethane (PU-PEO-$SO_3$) prepared by bulk modification was coated on a blood sac for electrohydraulic left ventricular assist device (ELVAD) implanted in dogs and its in vivo blood compatibility on shear stress was studied as compared with untreated Po. The effect of the wall shear stress on the protein adsorption unlike platelet adhesion is dependent on the surface characteristics of the material, although less proteins seem to be adsorbed in the region of the high shear stress. The thickness of total proteins adsorbed on PU-PEO-SOJ (400 ${\AA}$) by trans¬mission electron microscopy(TEM) was considerably lower than that of untreated PU(l,000~1,600 ${\AA}$), but PU-PEO-$SO_3$ showed high albumin adsorption, low fibrinogen and IgG adsorption, and low platelet adhesion as compared with untreated PU, suggesting that PU-PEO-$SO_3$ is more in vivo blood compatible. Therefore, it appears that such a blood compatible PU-PEO-$SO_3$ is useful for blood contacting biomaterials including artificial organs.

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