• Journal of Korean Medical classics
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• v.19 no.3
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• pp.210-227
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• 2006

Many historians presume that several kings included the crown prince were killed by poison in the Jo-Soon dynasty. Above all, there is every possibility of killing the crown prince So-Hyoon(昭顯) by poison. The crown prince So-Hyeon was detained for 8 years in Sim-Yang(瀋陽). He died suddenly in two month from coming home. According to an authentic record, official death causes were malaria. But there is little possibility that a young crown prince die of malaria at the age of 34. His dead body shows change of skin color and bleeding from the ear, eye, mouth, and nose. This is the sufficient evidence that he was killed by poison. King In-Jo have a doubt that he was ousted from his post by crown prince So-Hyeon in conspiracy with cheong imperial court. Especially, after the crown prince So-Hyeon's death, owing to cold attitude that king In-Jo shows and a tragic affair that occurred to the crown prince's family, king In-Jo is under suspicion as the mastermind of the murder. Another poisoners are Jo-So Yong(趙昭容) and Lee-Hyeong Ik(李聲益). Jo-So Yong, a royal harem, intrigue against the couple of crown prince So-Hyoon. Lee-Hyeong Ik that win king In-Jo's favor take charge of the medical treatment. We supposed that toxic substance is arsenic poison.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.2
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• pp.269-277
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• 2009

"Kenjurok" is a set of medical records of Todo Yoshimasu, a Japanese docotr in the eighteenth century, who suggested that all diseases have originated from a poison, which is his own pathological term describing abnormal states of the body, The 54 records in "Kenjurok" were analyzed in statistical respects, including gender ratio, demographic distribution of patients, types of diseases, and herbal prescriptions used. Among 54 cases, male patients outnumbered female, as much as four times. The patients were quite evenly distributed according to ages. In 23 cases out of 54, abdomen palpation data were mentioned, Majority of the prescriptions used were originated from Sanghanron(傷寒論:Treaties on Febrile Diseases)/Geumgeyoryak(金匱要略: Synopsis of Golden Chamber). In frequency of use of prescriptions, however, showed somewhat different result, that is although Sanghan/Geumge prescriptions were used most often, esoteric prescriptions handed down in his family also composed significant part. The speculations derived from these statistical results are: Although Todo favored abdommen palpation to locate the poison and to decide a prescription, the proportion of abdomen palpation was not as high as expectation, He did use prescriptions not only in Sanghan/Geumge, but also other diverse prescriptions, rather often than not, which are regarded unique Japanese traditional prescriptions including poisonous minerals such as mercury and arsenic.

• Journal of Oral Medicine and Pain
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• v.8 no.1
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• pp.83-96
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• 1983

The purpose of this study was detection of the poison from the acute cyanide and aresenic poisoned rabbits, The author administered KCN and $AS_2O_3$ to rabbits and caused acute poisoning, then analysed the teeth, dental pulp and jaws of the rabbits chemicotoxicologically and observed the specimen histopathologically. 1. In subcutaneausly injected group of KCN, a large amount of cyanide was detected in blood and lung and a small amount of cyanide was detected in teeth and dental pulp, but was not detected in jaws. 2. In orally administered group of KCN a large amount of cyanide was detected in blood, lung and dental pulp and a small amount of cyanide was detected in teeth and jaws. 3. In orally administered group of $AS_2O_3$, arsenic was detected markedly in teeth and jaws, but was detected a little in dental pulp. 4. In orally administered and heat-treated group of KCN, the author could detected cyanide in teeth, dental pulp and jaws. 5. In suvcutanelusly injected group of KCN, orally administered group of KCN and orally dministered group of $AS_2O_3$, histopathologic findings showed the congestion and hemorrhage in dental pulp. 6. In orally administerd group of $AS_2O_3$, the congestion and hemorrhage in buccal mucosa were found and the basal cell degeneration and fibrosis were found in palatal mucosa.

• Applied Biological Chemistry
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• v.36 no.2
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• pp.93-98
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• 1993

The purpose of this study is to determine the physicochemical properties in soybean oil during the hydrogenation by addition of phosphorus compounds and sulfur compounds is increased in soybean oil, decreased oleic acid and increased linoleic acid and stearic acid contents were found. When the sulfur compounds content is increased, solid fat content is increased at $10.0^{\circ}C$ and $21.1^{\circ}C$ and gradually decreased at $33.3^{\circ}C$ and $37.8^{\circ}C$. Higher melting point in hydrogenated soybean oil is observed on addition of phosphorus compounds compared to addition of sulfur compounds. When the sulfur compounds content is increased, conditions of selective hydrogenation are observed. Lead and arsenic are detected at a concentration of 0.01 ppm in a few kinds at each step of the refining process of soybean oil.