• Title/Summary/Keyword: Array Probe

Search Result 218, Processing Time 0.024 seconds

SNP Detection Using Indicator-free DNA Chip (비수식화 DNA를 이용한 유전자 검출)

  • Choi, Yong-Sung;Moon, Jong-Dae;Lee, Kyung-Sup
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2006.06a
    • /
    • pp.410-411
    • /
    • 2006
  • High throughput analysis using a DNA chip microarray is powerful tool in the post genome era. Less labor-intensive and lower cost-performance is required. Thus, this paper aims to develop the multi-channel type label-free DNA chip and detect SNP (Single nucleotide polymorphisms). At first, we fabricated a high integrated type DNA chip array by lithography technology. Various probe DNAs were immobilized on the microelectrode array. We succeeded to discriminate of DNA hybridization between target DNA and mismatched DNA on microarray after immobilization of a various probe DNA and hybridization of label-free target DNA on. the electrodes simultaneously. This method is based on redox of an electrochemical ligand.

  • PDF

Monitoring Cathodic Shielding and Corrosion under Disbonded Coatings

  • Varela, F.;Tan, M. YJ;Hinton, B.;Forsyth, M.
    • Corrosion Science and Technology
    • /
    • v.16 no.3
    • /
    • pp.109-114
    • /
    • 2017
  • Monitoring of corrosion is in most cases based on simulation of environmental conditions on a large and complex structure such as a buried pipeline using a small probe, and the measurement of thermodynamics and kinetics of corrosion processes occurring on the probe surface. This paper presents a hybrid corrosion monitoring probe designed for simulating deteriorating conditions wrought by disbonded coatings and for measuring current densities and distribution of such densities on a simulated pipeline surface. The concept of the probe was experimentally evaluated using immersion tests under cathodic protection (CP) in high resistivity aqueous solution. Underneath the disbonded area, anodic currents and cathodic currents were carefully measured. Anodic current densities were used to calculate metal loss according to Faraday's law. Calculated corrosion patterns were compared with corrosion damage observed at the surface of the probe after a series of stringent tests. The capability of the probe to measure anodic current densities under CP, without requiring interruption, was demonstrated in high resistivity aqueous solution. The pattern of calculated metal loss correlated well with corrosion products distribution observed at the array surface. Working principles of the probe are explained in terms of electrochemistry.

An Hybrid Probe Detection Model using FCM and Self-Adaptive Module (자가적응모듈과 퍼지인식도가 적용된 하이브리드 침입시도탐지모델)

  • Lee, Seyul
    • Journal of Korea Society of Digital Industry and Information Management
    • /
    • v.13 no.3
    • /
    • pp.19-25
    • /
    • 2017
  • Nowadays, networked computer systems play an increasingly important role in our society and its economy. They have become the targets of a wide array of malicious attacks that invariably turn into actual intrusions. This is the reason computer security has become an essential concern for network administrators. Recently, a number of Detection/Prevention System schemes have been proposed based on various technologies. However, the techniques, which have been applied in many systems, are useful only for the existing patterns of intrusion. Therefore, probe detection has become a major security protection technology to detection potential attacks. Probe detection needs to take into account a variety of factors ant the relationship between the various factors to reduce false negative & positive error. It is necessary to develop new technology of probe detection that can find new pattern of probe. In this paper, we propose an hybrid probe detection using Fuzzy Cognitive Map(FCM) and Self Adaptive Module(SAM) in dynamic environment such as Cloud and IoT. Also, in order to verify the proposed method, experiments about measuring detection rate in dynamic environments and possibility of countermeasure against intrusion were performed. From experimental results, decrease of false detection and the possibilities of countermeasures against intrusions were confirmed.

Controller Design for Decoupling of Scanning probe Data Storage System (두 축간 Coupling 을 고려한 Scanning probe Data Storage 시스템 제어기 설계)

  • Moon, Jun;Yun, Jae-Sang;Jeong, Ji-Young;Lee, Choong-Woo;Chung, Chung-Choo;Kim, Young-Sik
    • Transactions of the Society of Information Storage Systems
    • /
    • v.3 no.2
    • /
    • pp.73-80
    • /
    • 2007
  • Atomic Force Microscopy (AFM)방식을 이용한 Scanning probe Data Storage (SDS) 시스템은 array cantilever 를 이용하여 나노 단위로 데이터 읽기, 쓰기를 하는 시스템이다. 따라서 미디어가 있는 stage 의 x 축과 y 축 및 두 축간 coupling 을 고려한 제어기 설계가 요구된다. 본 논문은 SDS 시스템의 축간 coupling 을 고려하지 않은 기존의 제안된 LQG 에 PI 를 추가한 제어기 구조를 사용한다. 두 축간 coupling 공진의 영향을 최소화 하기 위해 convex optimization 으로 설계된 최적의 position profile를 기준 입력신호로 사용한다. 제안된 제어기를 SDS 시스템에 적용하여 모의실험을 하고 그 결과 position profile 로 인해 각 축간 coupling 공진 영향이 감소하여 tracking performance 가 기존의 LQG 제어기 보다 향상된 것을 확인한다.

  • PDF

Noninvasive blood glucose monitoring system based on NIR spectroscopy with a contact pressure control device

  • Kang, Na-Roo;Baek, Ju-Hyun;Woo, Young-Ah;Kim, Hyo-Jin
    • Proceedings of the PSK Conference
    • /
    • 2003.10b
    • /
    • pp.67.3-68
    • /
    • 2003
  • The purpose of this study is to improve repeatability of a non-invasive blood glucose measurement. The portable NIR system that was newly integrated by our lab includes a tungsten halogen lamp, a specialized reflectance fiber optic probe and a photo diode array type InGaAs detector, which was developed by a microchip technology based on the lithography. Reflectance NIR spectra of finger tip were recorded by using a fiber optic probe. The probe was fixed in the system and subjects put their finger on the probe head. (omitted)

  • PDF

Planar near-field antenna measurement method based on symplectic relation and reaction concept

  • Cho, Yong-Heui
    • International Journal of Contents
    • /
    • v.6 no.2
    • /
    • pp.6-9
    • /
    • 2010
  • Using symplectic relation and reaction concept, we propose a planar near-field antenna measurement method. A generalized probe compensation equation is deduced to obtain the probe correction formulation. To verify our approach, a reflector antenna with $1{\times}2$ horn array is fabricated and measured in the near-field measurement facility. The near-field measurement results are compared with the physical optics (PO) simulation. The results of measurement and simulation agree very well near to the mainbeam.

Signal Analysis of Eddy Current Array Probe According to Size Variation of FBH Defects (배열 와전류 프로브의 FBH 결함 크기 변화에 따른 신호 해석)

  • Kim, Ji-Ho;Lim, Geon-Gyu;Lee, Hyang-Beom
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.29 no.2
    • /
    • pp.137-144
    • /
    • 2009
  • In this paper, the signal analysis of eddy current array probe was performed to analyze the electromagnetic characteristics with the variation of FBH(flat bottomed hole) defects size on steam generator tube in NPP(nuclear power plants) using the electromagnetic finite element method. To obtain the electromagnetic characteristic of probes, the governing equation was derived from Maxwell's equations, and the individual problem was analyzed by using the 3-dimensional finite element method. For the simulation FBH defects were used. The depth of FBH defects were 20%, 40%, 60%, 80% and 100% of steam generator(SG) tube thickness, and it was assumed that the defects were located on the tube outside. And the operation frequencies of 100 kHz, 300 kHz and 400 kHz were used. Material of specimen was Inconel 600 which is usually used for SG tubes in NPP. The signal difference could be observed according to the size variation of depth of FBH defects and operation frequencies. The results in this paper can be helpful when the ECT(eddy current testing) signals from EC array probe are evaluated and analyzed.

Integrated Type DNA Chip Array and Gene Detection Using an Indicator-free DNA (집적형 DNA칩 어레이 및 비수식화 DNA를 이용한 유전자 검출)

  • Choi, Yong-Sung;Lee, Kyung-Sup
    • Proceedings of the KIEE Conference
    • /
    • 2006.07c
    • /
    • pp.1322-1323
    • /
    • 2006
  • This research aims to develop the multiple channel electrochemical DNA chip that has the above characteristic and be able to solve the problems. At first, we fabricated a high integration type DNA chip array by lithography technology. It is able to detect a plural genes electrochemically after immobilization of a plural probe DNA and hybridization of non-labeling target DNA on the electrodes simultaneously.

  • PDF

Fabrication of Combined Probes for Interstitial hyperthermia and Brachyradiotherapy (고 선량율 근접 및 온열치료 병용 삽입관의 제작과 특성)

  • Chu, Sung-Sil;Kim, Sung-Kyu
    • Proceedings of the Korean Society of Medical Physics Conference
    • /
    • 2004.11a
    • /
    • pp.85-87
    • /
    • 2004
  • We fabricated flexible thermoradiotherapy probes to alternated combination with Interstitial hyperthermia and Brachyradiotherapy thermoradiotherapy probe was coated by gold plate on polyethylene brachytherapy probe. When Agar phantom was heated 15 minute with 30 W radiofrequency power, temperature increased as 5oC for polyethylene probe and 20oC for gold coated polyethylene probe. We observed that the 1 cm square array would heat a volume with a 1.25 cm radius circular field cross section to therapeutic temperatures (90% relative SAR using Tm) and the 2 cm square array with a 1.75 cm radius rectangular field with central inhomogeneity. With 2 cm long electrode implants, we observed that the 1 cm square array would heat a 3 cm long sagittal section to therapeutic temperature (90% relative SAR using Tm). The histopathological changes associated with RF heating of normal canine brains have been correlated with thermal distributions. RF needle electrode heating was applied for 50 min to generate tissue temperatures of 43${\circ}$C. We obtained a quarter of the heated tissue material immediately after heating and sacrificed at intervals from 7${\sim}$30 days. The acute stage was demonstrated by liquefactive necrosis, pyknosis of neuronal element in the gray matter. Mild gliosis occurring around the necrosis was demonstrated in the last sacrificed (days30)canine brain.

  • PDF

Fabrication and Characterization of 32x32 Silicon Cantilever Array using MEMS Process (MEMS 공정을 이용한 32x32 실리콘 캔틸레버 어레이 제작 및 특성 평가)

  • Kim Young-Sik;Na Kee-Yeol;Shin Yoon-Soo;Park Keun-Hyung;Kim Yeong-Seuk
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.19 no.10
    • /
    • pp.894-900
    • /
    • 2006
  • This paper reports the fabrication and characterization of $32{\times}32$ thermal cantilever array for nano-scaled memory device applications. The $32{\times}32$ thermal cantilever array with integrated tip heater has been fabricated with micro-electro-mechanical systems(MEMS) technology on silicon on insulator(SOI) wafer using 9 photo masking steps. All of single-level cantilevers(1,024 bits) have a p-n junction diode in order to eliminate any electrical cross-talk between adjacent cantilevers. Nonlinear electrical characteristic of fabricated thermal cantilever shows its own thermal heating mechanism. In addition, n-channel high-voltage MOSFET device is integrated on a wafer for embedding driver circuitry.