• Title/Summary/Keyword: Aromatic herb drug

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The Screening of Antibiotics Resistance Inhibition of Herb Drugs entered in Korean Official Formulary (I) (공정서 수재생약 정유의 항생제 내성억제작용 검색(I))

  • Lee, Chung-Kyu;Kim, Dong-Myeong
    • Korean Journal of Pharmacognosy
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    • v.39 no.4
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    • pp.369-380
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    • 2008
  • The essential oils from 73 aromatic herb drugs entered on Korean official formularies were tested for antibioticresistance inhibitory effect. When the oils were combined with ampicillin (Am) or amoxicillin (Amx) they showed significant inhibitory effects on the growth of multi-drug resistant Staphylococcus aureus SA2 in considerably low concentration. The most effective combination were oils from Magnoliae Flos or Piperis longi Fructus ($25{\mu}g/mL$)-Am or Amx ($4{\mu}g/mL$).

The Screening of Antibiotics Resistance Inhibition of Herb Drugs entered in Korean Official Formulary (II) - Resistance Inhibition of 36 Essential Oils - (공정서 수재생약 정유의 항생제 내성억제작용 검색 (II) - 36종 정유의 내성억제작용 -)

  • Kim, Dong-Myeong;Heo, Kyung-Hee;Moon, Kyung-Ho;Lee, Chung-Kyu
    • Korean Journal of Pharmacognosy
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    • v.40 no.1
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    • pp.70-76
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    • 2009
  • Thirty six essential oils from herb drugs entered in Korean official formulary, which are frequently used in oriental region, were tested for antibiotic resistance inhibition. When the oils were combined with ampicillin (Am) or amoxicillin (Amx) they showed significant inhibitory effects on the growth of multi-drug resistant Staphylococcus aureus SA2 in considerably low concentration. The most effective combinations were oils from Acanthopanacis Cortex ($0.49{\mu}g/mL$) with Am and Cnidii Rhizoma and Lonicerae Flos (2.77 and $2.79{\mu}g/mL$, respectively) with Amx as shown in minimum resistance inhibitory concentrations.

Screening and Isolation of Antibiotic Resistance Inhibitors from Herb Materials-Resistance Inhibition of Volatile Components of Korean Aromatic Herbs

  • Lee, Chung-Kyu;Kim, Hye-Kyung;Moon, Kyung-Ho;Shin, Kuk-Hyun
    • Archives of Pharmacal Research
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    • v.21 no.1
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    • pp.62-66
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    • 1998
  • The resistance inhibitory activities of 54 odorant mixtures (essential oil) from 41 Korean aromatic herbs were tested against multi-drug resistant Staphylococcus aureus SA2, which has resistances to 10 usual antibiotics including chloramphenicol. As results, combinations of 28 kinds of samples from 21 herbs and chloramphenicol have resistance inhibitory activities in dose dependent manner.

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