생약학회지 (Korean Journal of Pharmacognosy)

  • 제40권1호
  • /
  • Pages.70-76
  • /
  • 2009
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

공정서 수재생약 정유의 항생제 내성억제작용 검색 (II) - 36종 정유의 내성억제작용 -

The Screening of Antibiotics Resistance Inhibition of Herb Drugs entered in Korean Official Formulary (II) - Resistance Inhibition of 36 Essential Oils -

  • 발행 : 2009.03.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Thirty six essential oils from herb drugs entered in Korean official formulary, which are frequently used in oriental region, were tested for antibiotic resistance inhibition. When the oils were combined with ampicillin (Am) or amoxicillin (Amx) they showed significant inhibitory effects on the growth of multi-drug resistant Staphylococcus aureus SA2 in considerably low concentration. The most effective combinations were oils from Acanthopanacis Cortex ($0.49{\mu}g/mL$) with Am and Cnidii Rhizoma and Lonicerae Flos (2.77 and $2.79{\mu}g/mL$, respectively) with Amx as shown in minimum resistance inhibitory concentrations.

키워드

참고문헌

  1. Baird-Parker, A. C. (1972) Classification and identification of staphylococci and their resistance to physical agents. The Staphylococci, 1-20
  2. Oeding, P. (1983) Taxonomy and identification. Staphylococci and staphylococcal infections. Clin. Epidemiol. Aspects., 1: 1-31
  3. Reading, C. and Cole, M. (1977) Clavulanic acid: a beta-lactamase- inhibiting beta-lactam from Streptomyces clavuligerus. Antimicrob. Ag. Chemother., 11: 852-857
  4. Neu, H. C. and Fu, K. P. (1978) Clavulanic acid, a novel inhibitor of beta- lactamases. Antimicrob. Ag. Chemother., 14: 650-655 https://doi.org/10.1128/AAC.14.5.650
  5. Paisley, J. W. and Washington, Jr., J. A. (1978) Combined activity of clavulanic acid and ticarcillin against ticarcillinresistant gram-negative bacilli. Antimicrob. Ag. Chemother., 14: 224-227
  6. Ball, A. P., Geddes, A. M., Davey, P. G, Farrell, I. D. and Brooked, G. R. (1980) Clavulanic acid and amoxacillin: A clinical, bacteriological and pharmacological study. Lancet, March 22: 620-623
  7. Arnoff, S. C., Jacobs, M. R., Johening, S. and Yamabe, S. (1984) Comparative activities of the β-lactamase inhibitors YTR 830. Sodium clavulanate and sulbactam combined with amoxicillin or ampicillin. Antimicrob. Ag. Chemother., 26: 580 https://doi.org/10.1128/AAC.26.4.580
  8. Jacobs, M. R., Arnoff, S. C., Johening, S., Shales, D. M. and Yamabe, S. (1986) Comparative activities of the β-lactamase inhibitors YTR 830. Clavulanate and sulbactam combined with ampicillin and broad spectrum penicillins against defined $\beta$-lactamase-producing aerobic gram-negative bacilli. Antimicrob. Ag. Chemother., 29: 980 https://doi.org/10.1128/AAC.29.6.980
  9. Retsema, J. A., English, A. R., Girard, A., Lynch, J, E., Anderson, M., Brennan, L. Cimochowski, C., Haiella, J., Norcia, W. and Sawyer, P. (1986) Sulbactam/ampicillin: in vitro spectrum, potency and activity in models of acute infection. Rev. Infect. Dis., 8: S528 https://doi.org/10.1093/clinids/8.Supplement_5.S528
  10. Kuck, N. A., Jacobus, N. V., Petersen, P. J., Weiss, W. J. and Testa, R. T. (1989) Comparative in vitro and in vivo activities of piperacillin combined with the $\beta$-lactamase inhibitors tazobactam, clavulanic acid and sulbactam. Antimicrob. Ag. Chemother., 33: 1964 https://doi.org/10.1128/AAC.33.11.1964
  11. Kim, H. K., Park, S. W., Park, J. N., Moon, K. H. and Lee, C. K. (1995) Screening and isolation of antibiotic resistance inhibitors from herb materials. . Resistance inhibition of 21 Korean plants, Nat. Prod. Sci., 1: 50-54 https://doi.org/10.1016/S0378-8741(01)00411-1
  12. Park, J. N., Kim, H. K., Moon, K. H. and Lee, C. K. (1997) Screening and isolation of antibiotics resistance inhibitors from herb materials. . Inhibitory effects ofChwinamool(Aster scaber), Kor. J. Pharmacogn., 28: 162-165
  13. Lee, C. K., Kim, H. K., Moon, K. H. and Shin, K. H. (1998) Screening and isolation of antibiotic resistance inhibitors from herb materials. III. − Resistance inhibition of volatile components of Korean aromatic herbs. Arch. Pharm. Res., 21: 62-66 https://doi.org/10.1007/BF03216754
  14. Kim, H. K., Moon, K. H. Ryu S. Y., Moon D. C. and Lee, C. K. (1998) Screening and isolation of antibiotic resistance inhibitors from herb materials. IV. − Resistance inhibitors from Anethum graveolens and Acorus graminus. Arch. Pharm. Res., 21: 62-66 https://doi.org/10.1007/BF03216754
  15. Kim, H-K., Moon, K. H. and Lee, C. K. (2000) Screening and isolation of antibiotics resistance inhibitors from herb materials. V. − Resistance inhibition by acorenone from Acorus gramineus Solander. Nat. Prod. Sci., 6: 36
  16. Moon, K. H., Kwon, J. Y. Kim, H-K, Seo, B. S. and Lee, C. K. (2003) Effect of hexane extract of Acori graminei Rhizoma on the growth of chloramphenicol resistant bacteria. Nat. Prod. Sci., 9: 183-185
  17. Moon, K., Seo, B. S., Kim, H., Park, M. and Lee, C. K.(2004) Effects of essential oils of several aromatic plants on the growth of antibiotic resistant Staphylococcus aureus SA2. Yakhak-Hoeji, 48: 27-29
  18. Moon, K. H., Kwon, J. Y., Park, M., Kim, H. and Lee, C. K. (2004) Effects of hexane extract of Acori graminei Rhizoma on chloramphenicol acetyltrans- ferase of Staphylococcus aureus SA2. Yakhak-Hoeji, 48: 30-33
  19. Korean Food and Drug Administration (2007) The Korean Pharmacopoeia, Ninth ed., , Part 2
  20. Korean Food and Drug Administration (2007) The Korean Herbal Pharmacopoeia
  21. Lee, C. K. and Kim, D. (2008) The screening of antibiotics resistance inhibition of herb drugs entered in Korean official formulary (I). Kor. J. Pharmacogn., 39: 369-380