• Title/Summary/Keyword: Approximate F Test

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Approximate analyses of reinforced concrete slabs

  • Vecchio, F.J.;Tata, M.
    • Structural Engineering and Mechanics
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    • v.8 no.1
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    • pp.1-18
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    • 1999
  • Procedures are investigated by which nonlinear finite element shell analysis algorithms can be simplified to provide more cost effective approximate analyses of orthogonally-reinforced concrete flat plate structures. Two alternative effective stiffness formulations, and an unbalanced force formulation, are described. These are then implemented into a nonlinear shell analysis algorithm. Nonlinear geometry, three-dimensional layered stress analyses, and other general formulations are bypassed to reduce the computational burden. In application to standard patch test problems, these simplified approximate analysis procedures are shown to provide reasonable accuracy while significantly reducing the computational effort. Corroboration studies using various simple and complex test specimens provide an indication of the relative accuracy of the constitutive models utilized. The studies also point to the limitations of the approximate formulations, and identify situations where one should revert back to full nonlinear shell analyses.

Estimation of Gauge R&R by Variance Components of Measurement ANOVA (측정 ANOVA의 분산성분에 의한 게이지 R&R 추정)

  • Choi, Sung-woon
    • Journal of the Korea Safety Management & Science
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    • v.12 no.1
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    • pp.199-205
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    • 2010
  • The research proposes the three-factor random measurement models for estimating the precision about operator, part, tool, and various measurement environments. The combined model with crossed and nested factors is developed to analyze the approximate F test by degrees of freedom given by Satterthwaite and point estimation of precisions from expected mean square. The model developed in this paper can be extended to the three useful models according to the type of nested designs. The study also provides the three-step procedures to evaluate the measurement precisions using three indexes such as SNR(Signal-To-Noise Ratio), R&R TR(Reproducibility&Repeatability-To-Total Precision Ratio), and PTR(Precision-To-Tolerance Ratio), The procedures include the identification of resolution, the improvement of R&R reduction, and the evaluation of precision effect.

A TRIPLE MIXED QUADRATURE BASED ADAPTIVE SCHEME FOR ANALYTIC FUNCTIONS

  • Mohanty, Sanjit Kumar
    • Nonlinear Functional Analysis and Applications
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    • v.26 no.5
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    • pp.935-947
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    • 2021
  • An efficient adaptive scheme based on a triple mixed quadrature rule of precision nine for approximate evaluation of line integral of analytic functions has been constructed. At first, a mixed quadrature rule SM1(f) has been formed using Gauss-Legendre three point transformed rule and five point Booles transformed rule. A suitable linear combination of the resulting rule and Clenshaw-Curtis seven point rule gives a new mixed quadrature rule SM10(f). This mixed rule is termed as triple mixed quadrature rule. An adaptive quadrature scheme is designed. Some test integrals having analytic function integrands have been evaluated using the triple mixed rule and its constituent rules in non-adaptive mode. The same set of test integrals have been evaluated using those rules as base rules in the adaptive scheme. The triple mixed rule based adaptive scheme is found to be the most effective.

Optimal Design of the Passenger Vehicle Aluminum Seat for Weight Reduction and Durability Performance Improvement (승용차용 알루미늄 시트의 경량화 및 내구성능 향상을 위한 최적설계)

  • Kim Byung-Kil;Kim Min-Soo;Kim Bum-Jin;Heo Seung-Jin
    • Transactions of the Korean Society of Automotive Engineers
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    • v.13 no.3
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    • pp.58-63
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    • 2005
  • In order to minimize weight of vehicle seat, an optimum design of aluminum seat is presented while satisfying stress and fatigue life constraints. In this study, the analysis model is validated by comparing it's stress with that of test. Then, two-level orthogonal array is used to estimate the design sensitivity for 7 design variables. Finally, the sequential approximate optimization (SAO) is performed using the constructed RSM models. The approximate RSM models are sequentially updated using the analysis results corresponding to the approximate optimum obtained during the SAO. After 14 analyses, the SAO gives an optimal design that can reduce 16.7$\%$ of weight while increasing 369$\%$ of fatigue life and satisfying stress constraint.

New Family of the Exponential Distributions for Modeling Skewed Semicircular Data

  • Kim, Hyoung-Moon
    • The Korean Journal of Applied Statistics
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    • v.22 no.1
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    • pp.205-220
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    • 2009
  • For modeling skewed semicircular data, we derive new family of the exponential distributions. We extend it to the l-axial exponential distribution by a transformation for modeling any arc of arbitrary length. It is straightforward to generate samples from the f-axial exponential distribution. Asymptotic result reveals two things. The first is that linear exponential distribution can be used to approximate the l-axial exponential distribution. The second is that the l-axial exponential distribution has the asymptotic memoryless property though it doesn't have strict memoryless property. Some trigonometric moments are also derived in closed forms. Maximum likelihood estimation is adopted to estimate model parameters. Some hypotheses tests and confidence intervals are also developed. The Kolmogorov-Smirnov test is adopted for goodness of fit test of the l-axial exponential distribution. We finally obtain a bivariate version of two kinds of the l-axial exponential distributions.

Mouse Single Oral Dose Toxicity Test of Red Koji Fermented Scutellariae Radix Aqueous Extracts (홍국 발효 황금의 마우스 단회 경구투여 독성시험)

  • Park, Jae-Chan;Choi, Hae-Yun;Kim, Jong-Dae
    • Herbal Formula Science
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    • v.21 no.1
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    • pp.186-199
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    • 2013
  • Objectives : The objectives of this study was to obtain acute information (single oral dose toxicity) of Red-Koji (Monascus purpureus 12002) Fermented Scutellariae Radix Aqueous Extracts (fSR), has been traditionally used in Korean medicine for treating various diseases including inflammatory diseases. Methods : In order to observe the 50% lethal dose (LD50), approximate lethal dosage (ALD) and target organs, fSR powders were once orally administered to female and male ICR mice at dose levels of 2,000, 1,000, 500 and 0 (control) mg/kg (body weight.). The mortality and changes on body weight, clinical signs and gross observation were monitored during 14days after single oral treatment of fSR with organ weights and histopathological observations of 12 types of principle organs. Results : After single oral treatment of fSR, we could not find any mortality and toxicological evidences up to 2,000 mg/kg treated group, the limited dosages in rodents, on the body and organ weights, clinical signs, gross and histopathological observations, except for some accidental findings. Conclusions : The results obtained in this study suggest that the LD50 and ALD of fSR in both female and male mice after single oral treatment were considered as over 2,000 mg/kg because no mortalities were detected up to 2,000 mg/kg and can be safety used in clinics.

Single-Dose Toxicity and Four Week Repeated-Dose Toxicity Study on Tensolin-F® (3,9-diferuloyl-6-oxopterocarpen) (Tensolin-F® (3,9-diferuloyl-6-oxopterocarpen)의 단회 독성시험 및 4주 반복투여 독성시험)

  • Kim, Keun-Su;Park, Sung-Min;Lee, Nam-Jin;Pyo, Hyeong-Bae;Chai, Hee-Yul;Jung, Yu-Ri;Lin, Chun-Mai;Kim, Sun-Hee;Lee, Hye-Young;Kang, Jong-Koo
    • Toxicological Research
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    • v.23 no.4
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    • pp.405-413
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    • 2007
  • This study was to investigate single and repeated-dose toxicities of Tensolin-$F^{(R)}$, an anti-wrinkle agent, in Sprague-Dawley (SD) rats or ICR mice. In single-dose oral toxicity study, the test materials were administered once by gavage to male and female SD rats at dose levels of 0 and 2,000 mg/kg. No dead animals and abnormal necropsy findings were found in control and Tensolin-$F^{(R)}$ treated group. Therefore, the approximate lethal dose of Tensolin-$F^{(R)}$ was considered to be higher than 2,000 mg/kg in rats. In the 4-week repeated oral toxicity study, the test material was administered once daily by gavage to male and female ICR mice at dose levels of 0, 25, 50 and 100 mg/kg/day for 4-weeks. In the results, no abnormality was observed in mortality, clinical findings, body weight changes, food and water consumptions, opthalmoscopic findings, necropsy findings, histopathological findings. In hematological analysis, there was a trend of increase in reticulocyte at male 25 mg/kg, although such changes were in normal ranges. On the other hand, there was a trend of decrease in hemoglobin at female 50, 100 mg/kg, such changes were in normal ranges. In addition, serum biochemical parameters including sodium, BUN and chloride increased at 25, 50 and 100 mg/kg. Relative organ weights of right testis, brain, lung and left epididymis were increased in 100 mg/kg groups of male rats in contrast to not change in female groups. However, these changes of relative organ weights, hematological and serum biochemical parameters were not accompanied with related signs such as histopathological changes or clinical findings. In conclusion, 4-week repeated oral dose of Tensolin-$F^{(R)}$ to ICR mice did not cause apparent toxicological change at the dose of 25, 50, 100 mg/kg body weight. Consequently the no-observed-adverse-effect level (NOAEL) for Tensolin-$F^{(R)}$ in ICR mice following gavage for at least 4-week is higher than 100 mg/kg/day.

Studies on the Comparison of Physicochemical Properties and the Presumption of Sensory Quality of Japonica Rice Varieties Cultivated in Korea and Japan (한국과 일본의 자포니카종 쌀에 대한 이화학적 특성의 비교 및 관능품질의 추정에 관한 연구)

  • 홍원표;이성갑;박승남
    • The Korean Journal of Food And Nutrition
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    • v.14 no.6
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    • pp.596-604
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    • 2001
  • Twelve varieties of Korean rice and ten varieties of Japanese rice were selected. After being milled. they were analyzed about various physicochemical properties such as moisture, protein and amylose, a -amylase activity, gelatinization properties. And after being cooked with proper amount of water texture and other physical properties were measured by Texturometer, Tensipresser and Rheolograph-micro. Finally the sensory evaluation test was carried out. The results were as follows. 1. In case of protein contents, amylose contents and $\alpha$-amylase activity, Korean rice had a slightly higher value than Japanese As a consequence. Korean rice showed a little stronger hardness and a little weaker stickiness compared with Japanese rice. 2. Amylose contents showed very high correlation with other physicochemical properties and peak viscosity and gelatinization temperature of RVA, the ratio of stickiness to hardness( -Hl/Hl ) of Texturometer and the tan $\delta$(the ratio of dynamic loss to dynamic viscoelasticity) of Rheolograph-micro showed high correlation with other analyzed properties. 3. The ( -/+)work balance of low compression test(25% ) of Tensipresser analysis(texture analysis on the surface of cooked rice) and tan f of Rheolograph-micro showed very high correlation with sensory evaluation results. By using this parameters as major independent variables, some trials to derive high confidence multiple regression equations were accomplished. By the equations it would be possible to make an approximate pre-estimate of eating quality for unknown japonica rice.

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Dot-Blot Immunoassay of Fasciola gigantica Infection using 27 kDa and Adult Worm Regurge Antigens in Egyptian Patients

  • Kamel, Hanan H.;Saad, Ghada A.;Sarhan, Rania M.
    • Parasites, Hosts and Diseases
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    • v.51 no.2
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    • pp.177-182
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    • 2013
  • The purpose of the present study was to evaluate the potential role of the 27-Kilodalton (KDa) antigen versus Fasciola gigantica adult worm regurge antigens in a DOT-Blot assay and to assess this assay as a practical tool for diagnosis fascioliasis in Egyptian patients. Fasciola gigantica antigen of an approximate molecular mass 27- (KDa) was obtained from adult worms by a simple elution SDS-PAGE. A Dot-Blot was developed comparatively to adult worm regurge antigens for the detection of specific antibodies from patients infected with F. gigantica in Egypt. Control sera were obtained from patients with other parasitic infections and healthy volunteers to assess the test and compare between the antigens. The sensitivity, specificity, positive and negative predictive values of Dot-Blot using the adult worm regurge were 80%, 90%, 94.1%, and 69.2% respectively, while those using 27-KDa were 100% which confirms the diagnostic potential of this antigen. All patients infected with Fasciola were positive, with cross reactivity reported with Schistosoma mansoni serum samples. This 27-KDa Dot-Blot assay showed to be a promising test which can be used for serodiagnosis of fascioliasis in Egyptian patients especially, those presenting with hepatic disease. It is specific, sensitive and easy to perform method for the rapid diagnosis particularly when more complex laboratory tests are unavailable.

Mouse Single Oral Dose Toxicity Test of Lactobacillus-fermented Araliae Continentalis Radix Aqueous Extracts (fACR) (독활의 복합 유산균 발효 추출액의 마우스에 대한 단회경구투여 독성시험)

  • Jung, Young-Mi;Ku, Sae-Kwang;Lee, Dong Sub;Kwon, Kisang
    • Journal of Life Science
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    • v.26 no.2
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    • pp.204-211
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    • 2016
  • The objective of this study was to obtain acute (single) oral dose toxicity information on Lactobacillus-fermented Araliae Continentalis Radix aqueous extracts (fACR) in female and male ICR mice, as compared with Araliae Continentalis Radix aqueous extracts (ACR). After administering a single oral dose of fACR, no treatment-related mortalities were observed within 14 days after the end of treatment up to 2,000 mg/kg, the maximum dosage for rodents of both sexes; moreover, no fACR treatment-related changes in the body and organ weights, clinical signs, necropsy, and histopathological findings were detected in this experiment. In addition, no ACR 2,000 mg/kg treatment-related mortalities, clinical signs, body and organ weights, or gross and histopathological findings were observed, as compared with equal genders of vehicle control. The results obtained in this study suggest that fACR is non-toxic in mice and is, therefore, likely to be safe for clinical use. The LD50 and approximate LD in female mice and male mice, respectively, were considered after a single oral dose of fACR over 2,000 mg/kg, the maximum dosage for rodents. In addition, no specific targets or clinical signs were detected in the present study. ACR 2,000 mg/kg-treated mice also did not show any treatment-related mortalities, clinical signs, changes to body and organ weights, or gross and histopathological findings, as compared with equal genders of vehicle control.