• Journal of Chest Surgery
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• 제35권2호
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• pp.102-112
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• 2002

배경: 본 연구는 대동맥근부를 침범한 상행대동맥류 환자에서 composite valve graft를 이용한 대동맥근부 치 환술 결과를 알아보고자 하였다. 대상 및 방법: 1995년 4월부터 2001년 6월가지 composite valve graft를 이용한 대동맥근부 치환술 환자 56명을 대상으로 후향적으로 조사하였다. 대동맥판막 폐쇄부전은 50명(89%), Mafan증후군이 18명(32%), 그리고 이엽성 대동맥판막이 7명(12.5%)에서 동반되었다. 진단은 대동맥판륜 확장증 30명(53.6%), 대동맥 박리증 13명(23.2%), 대동맥근부를 침범한 상행대동맥류 11명(17.6%), 그리고 대동맥염이 2명(3.6%)이였다. 대동맥 파열로 인한 심낭 압전 및 심인성 쇽은 2명에서 있었으며 과거에 심장이나 상행대동맥 수술을 받은 환자는 9명(16%)이었다. 근부치환술시 사용된 수술방법button술식 51명(91%), 변형 Cabrol 술식 4명, classic Bentall 술식을 1명에서 시행하였다. 동반수술은 대동맥궁 치환술 24명(43%), 관상동맥우회술 8명(14.3%), 승모판 성형술 2명 및 재치환술 1명, 기타 7명이었다. 평균 순환정지, 체외순환및 대동맥차단 시간은 각각 21$\pm$14분(6-60분), 186$\pm$68분과 132$\pm$42분이었다. 결과: 조기 사망은 1명(1.8%)에서 있었고 술후 합병증으로는 심기능 부전이 16명(28.6%), 출혈로 인한 재수술 7명(12.5%), 심낭삼출 2명, 그리고 기타가 6명이었다. 술후 생존자 55명중 53명(96.4%)에서 평균 23.2$\pm$18.7개월(1-75개월)을 추적하였다. 만기 사망은 외상성 뇌출혈로 사망한 1명을 포함해 2명(3.8%)이었으며 대동맥근부 치환술과 관련한 만기 사망률은 1.9%였다. 한편 술후 1년과 6년 survival rate는 각각 98.1$\pm$1.9%와 93.275.1%였다. 대동맥근부 치환술과 관련한 합병증으로 재수술이 2명에서 시행되었으며(3.8%), 1년과 6년 후 재수술로부터의 freedom rate는 각각 97.872.0%와 65.3$\pm$26.7%였다. 잔여 대동맥에 대한 수술은 술전에 동반된 흉복부대동맥류의 확장으로 2명에서 흥복부대동맥류 치환술을 시행하였다.

• Journal of Chest Surgery
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• 제24권1호
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• pp.36-40
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• 1991

Between November, 1981 and July, 1989, 4 patients, 3 male and 1 female patients ranging in age from 36 to 45 years, were operated on for aortic insufficiency associated with uncomplicated annuloaortic ectasia. All patients were in New York Heart Association class III. Two patients had clinical stigmata of the Marfan syndrome. The surgical treatment consisted of. supracoronary replacement of ascending aorta with vascular graft and replacement of the aortic valve in our first case. and composite graft replacement of the ascending aorta and aortic valve with reimplantation of the coronary arteries in subsequent 3 cases. Our first patient developed aneurysm of proximal aorta and pseudoaneurysm of distal aortic anastomosis 5 years postoperatively. One patient among the three patients with Ben-tall operation, died of ventricular fibrillation and myocardial failure during immediate postoperative period. Remaining 2 patients were in NYHA class I with follow-up of 16 months and 20 months respectively.

• Journal of Chest Surgery
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• 제23권3호
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• pp.488-500
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• 1990

Author compared the effect of surgical methods between 40 patients who received mitral valve replacement with complete excision of the mitral valve[resected group] and 41 patients who received mitral valve replacement with preservation of posterior chorda tendineae and posterior mitral leaflet[preserved group] from 1985. 2. to 1989. 4. at cardiothoracic department of Pusan National University Hospital.v 1. There was no significant difference between the preserved group and resected group in cardiopulmonary bypass time and aortic cross clamping time and NYHA classification. 2. In preserved group of Mitral stenosis and Mitral regurgitation, the left ventricular functions were much improved after mitral valve replacement than resected group, but there was not so difference between the preserved group and reserved group in Mitral steno-regurgitation. 3. There were remarkable decrease in complication rate in preserved group compared to resected group. And also the death rates were remarkably decreased in preserved group which was 4.9% compared to resected group which was 17.5%. As the preservation of the posterior mitral leaflet and chorda tendineae during mitral valve replacement in mitral valve disease showed significantly improved effects in the maintaining of left ventricular function and reducing the postoperative complication, I assume the preservation of posterior mitral leaflet and chordae during mitral valve replacement will bring better result.

• Journal of Chest Surgery
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• 제21권4호
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• pp.727-733
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• 1988

Two cases of the discrete membranous subaortic stenosis were experienced at the Department of Thoracic & Cardiovascular Surgery, National Medical Center, Seoul, Korea. Case I was 31 years old male with a history of aortic valve replacement[Ionescu-Shiley, 19mm] at the other hospital in 1980. Heart failure was noticed 6 years later. On cardiac catheterization, pressure gradient between left ventricle 4 aorta was 104 mmHg, but subvalvular aortic stenosis was not detected by preoperative 2-D echo <% left ventriculogram. Above case revealed stenoinsufficiency of the prosthetic valve. Under the diagnosis of the prosthetic valve failure, re-do aortic valve replacement[Bjork-Shiley, 23 mm] was done. During operation, the discrete membranous subaortic stenosis was incidentally found, and it was completely resected. So we thought that above discrete membranous subaortic stenosis was not detected at first operation, and it was progressed during 6 years, and accelerated the degeneration of the prosthetic valve. Case II was 20 years old female. Her complaints were exertional dyspnea, angina, syncope, which were aggravated since 5 years ago. 2-D echo <% left ventriculogram revealed the discrete membranous subaortic stenosis. Pressure gradient was 20 mmHg, but her symptoms were serious. Associated cardiac anomaly was the persistent left superior vena cava without connection with right superior vena cava. Complete excision of the membranous tissue was done. Post-operative pressure gradient between left ventricle & aorta was absent, and her complaints were nearly subsided. Both cases were type I according to the Newfeld classification of the discrete subvalvular aortic stenosis, and complete excision of the membranous tissue was done without myotomy or mymectomy. And short-term follow-up results[Case I:2 years, Case II: 1 ~ years] were good except soft systolic murmur[grade II/VI] at the aortic area in both cases.

• Journal of Chest Surgery
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• 제51권4호
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• pp.231-240
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• 2018

Background: Analyses of the efficacy and safety of transcatheter aortic valve replacement (TAVR) in most countries have been based on outcomes obtained in accordance with national practice guidelines and monitoring protocols. The purpose of this study is to share our experience regarding the process for establishing guidelines and monitoring protocols for the use of TAVR in Korea, in the hopes that it may be helpful to others undergoing a similar process in their own country. Methods: The Korean guidelines for TAVR were established on June 1, 2015 in through a tri-party agreement involving the Department of Health and Welfare, the Korean Society of Thoracic and Cardiovascular Surgery and the Korean Society of Cardiology. We agreed to monitor the guidelines transparently and to exchange opinions regarding amendments or continuation of its contents after 3 years of monitoring. Results: The monitoring meetings were not held as regularly as agreed, and monitoring was also made difficult by insufficient and incomplete data. Nevertheless, during the meetings, measures to improve the monitoring process were discussed, and accordingly, an agreement was made to continue the monitoring process, with the aim of completing data collection by 2018. Conclusion: Compliance with guidelines is critical for assessing the efficacy and safety of TAVR. Moreover, the TAVR monitoring process must be properly conducted for an accurate evaluation to be made. Any country planning to introduce TAVR may encounter difficulties with regards to the optimal initiation strategy and subsequent monitoring. Nevertheless, continued efforts should be made to persuade the government and the corresponding medical societies to facilitate the optimal application of TAVR.

• Journal of Chest Surgery
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• 제45권2호
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• pp.80-84
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• 2012

Background: The aim of this study is to evaluate our institutional results of the aortic valve replacement through minimally invasive approaches compared with conventional sternotomy. Materials and Methods: From August 1997 to July 2010, 838 patients underwent primary isolated aortic valve replacement. Of them, 73 patients underwent surgery through minimally invasive approaches (MIAS group) whereas 765 patients underwent surgery through the conventional sternotomy (CONV group). Clinical outcomes were compared using a propensity score matching design. Results: Propensity score matching yielded 73 pairs of patients in which there were no significant differences in baseline profiles between the two groups. Patients in the MIAS group had longer aortic cross clamp than those in the CONV group ($74.9{\pm}27.9$ vs.. $66.2{\pm}27.3$, p=0.058). In the MIAS group, conversion to full sternotomy was needed in 2 patients (2.7%). There were no significant differences in the rates of low cardiac output syndrome (4 vs. 8, p=0.37), reoperation due to bleeding (7 vs. 6, p=0.77), wound infection (2 vs. 4, p=0.68), or requirements for dialysis (2 vs. 1, p=0.55) between the two groups. Postoperative pain was significantly less in the MIAS group than the conventional group (pain score, $3.79{\pm}1.67$ vs. $4.32{\pm}1.56$; p=0.04). Conclusion: Both minimally invasive approaches and conventional sternotomy had comparable early clinical outcomes in patients undergoing primary isolated aortic valve replacement. Minimally invasive approaches significantly decrease postoperative pain.

• Journal of Chest Surgery
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• 제43권3호
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• pp.260-265
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• 2010

배경: 복합 인공 판막 도관(composite valve graft) 치환술은 다양한 대동맥 근부 질환들에 사용되어 왔다. 이 연구의 목적은 이 술기에 대한 중기 결과를 알아보는 데 있다. 대상 및 방법: 1992년부터 2009년까지 대동맥 근부 복합 인공 판막 도관 치환술을 받은 39명의 환자를 대상으로 후향적 조사를 하였다. 환자들의 평균 나이는 $49.2{\pm}16.4$세였고, 평균 추적 관찰 기간은 $64.2{\pm}53.4$개월이었다(최대 기간, 176개월). 결과: 4명(8.6%)의 병원 내 사망이 있었고 모두 응급 대동맥 박리인 경우였다. 4명의 만기 사망이 있었는데 2명은 잔류 대동맥류, 1명은 경막하 출혈, 1명은 판막 주위 역류가 원인이었다. 생존율은 각각 1년, 5년, 10년에 93.5%, 85.0%, 85.0%였다. 추적 관찰 기간 동안 3명의 환자에서 뇌혈관 사고가 발생하였고, 뇌혈관 사고로부터의 자유율은 각각 1년, 5년, 10년에 97.0%, 92.0%, 80.0%였다. 모든 뇌혈관사고는 출혈과 연관된 합병증이었다. 결론: 복합 인공 판막 도관을 이용한 대동맥 근부 치환술은 좋은 결과를 보여 왔다. 그러므로 이 술기는 다양한 대동맥 근부 질환의 치료에 좋은 방법이라 할 수 있다.

• Journal of Chest Surgery
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• 제31권10호
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• pp.1009-1013
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• 1998

대동맥근부를 포함한 대동맥 판막 심내막염은 적극적인 내과적 및 외과적 치료를 해도 염증의 재발이나 사망률이 높은 질환이다. 자가폐동맥판막을 이용하여 전대동맥근부치환술은 이식편이 생체 조직이고, 면역학적으로도 안전한 조직이라 술후 항응고요법이 요구되지 않는 술식이다. 저자들은 38세된 여자환자에서 대동맥근부를 포함한 대동맥 판막 심내막염 환자에서 Ross술식을 이용하여 성공적으로 치험하였고 수술후 3개월간 추적중 양호한 상태이다.

• Journal of Chest Surgery
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• 제21권2호
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• pp.283-290
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• 1988

St. Jude Medical cardiac valve replacement was performed in 90 consecutive patients from Jan. 1984 to Dec. 1987. 54 had mitral, 12 had aortic and 24 had multiple valve replacement. Follow up extended for 1 to 47 months[mean 17.1 month] with a cumulative period of 1351 months. The overall actuarial survival rate at 4 years was 87.1% and overall hospital mortality was 6.7%. The linearlized incidence of thrombotic obstruction, thromboembolism, valve failure was 0.8% / pt. yr. each. The lower incidence of valve related mortality or morbidity was statistically significant. The performance of the St. Jude Medical mechanical valve was excellent compared to other substitute valves and has low incidence of thromboembolism or valve failure.

• Journal of Chest Surgery
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• 제32권6호
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• pp.591-594
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• 1999

대동맥판상부 협착증은 발살바동 상부에서부터 협착이 존재하는 비교적 흔치않은 선천성 질환이다. William 증후군없이 선천적으로 대동맥판 상부 협착증과 대동맥 좌관상판엽의 형성부전으로 인한 대동맥판 폐쇄부전증으로 진단받은 39세 여자환 悶“\ulcorner대동맥판막 치환술 및 Vascutek graft를 이용한 판탈롱 대동맥성형술을 시행 하였다. 환자의 술후경과는 좋았고 술후 9일째 퇴원하였다.