• Biomolecules & Therapeutics
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• v.11 no.3
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• pp.190-195
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• 2003

To assess the genotoxicity of AS6, several classical toxicological tests were performed. In Ames test, AS6 did not show any transformation of revertant with or without S-9 metabolic activating system, indicating the lack of mutagenic effect of the compound. To assess clastogenic effect, in vivo micronucleus and in vitro chromosomal aberration assays were performed using male ICR mice and Chinese hamster lung (CHL) fibroblast cells, respectively. Chromosomal aberration was not induced regardless of the presence of S-9 metabolic activating system. In addition, AS6 did not cause any increase in the incidence of micronucleated polychromatic erythrocytes at any of the dose levels, suggesting little clastogenicity in vitro or in vivo. Taken together, these results demonstrate that AS-6 has no mutagenic effect in our test system.

• Proceedings of the Korea Association of Information Systems Conference
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• 2005.12a
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• pp.359-366
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• 2005

As the ubiquitous computing technology (uT) is prevailing, applying uT is more likely to transform the legacy way of doing business to a new way with the goals of ubiquitous computing: strategic use of information resources by using them everywhere, every time, with any devices for any services. These opportunities naturally require the provision to assess the degree of the transformation from the legacy IT-based e-business to the uT-based business. However, research about assessing the degree of u-transformation has been still very few. Moreover, even deciding what is ubiquitous or not is obscure. Hence, this paper aims to propose the methodology for assessing the degree of u-transformation oriented by the teleology of ubiquitous service, which intends to fully make use of uT in creating new business of next generation. Through the literature review, we developed the methodology to check whether the provided service is ubiquitous or not based on the capabilities that technologies have. and then, the methodology developed to assess the technical requirements that the uT should have when the transformation is considered through the focus group interview based on the literature review of the capability. A two-layered approach is introduced to assess not only the level of ubiquity but also the degree of u-transformation.

• Journal of Pharmacopuncture
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• v.27 no.2
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• pp.154-161
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• 2024

Objectives: The objective of this study was to assess the genotoxicity of a no-pain pharmacopuncture (NPP) extract developed in 2022 using a bacterial reverse mutation assay, aiming to further substantiate the safety profile of NPP. Methods: The genotoxicity evaluation involved a bacterial reverse mutation assay to assess the mutagenic potential of NPP extracts with and without metabolic activation. Histidine-requiring Salmonella typhimurium strains (TA98, TA100, TA1535, and TA1537) and tryptophan-requiring Escherichia coli strains (WP2uvrA) were used in the assay. Results: The NPP extract did not induce a revertant colony count exceeding two times that of the negative control at any dose level in any of the tested strains, both with and without metabolic activation. Additionally, no growth inhibition or precipitation was observed in the presence of NPP. Conclusion: Based on the findings, it can be concluded that the NPP extract exhibited no mutagenic potential in the in vitro genotoxicity tests conducted.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.22 no.52
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• pp.109-116
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• 1999

Flow Shop with Multiple Processors(FSMP) scheduling involves sequencing jobs in a flow shop where, at any processing stage, there exists one or more identical processors. Any methodology to determine the optimal mean flow time for this type of problem is NP-complete. This necessitates the use of sub-optimal heuristic methods to address problems of moderate to large scale. This paper presents global lower bounds on FSMP mean flow time problems which may be used to assess the quality of heuristic solutions when the optimal solution is unknown.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.14 no.3
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• pp.181-187
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• 2014

Dealing with uncertainty is always a challenging problem. Intuitionistic fuzzy sets was presented to manage situations in which experts have some membership and non-membership value to assess an alternative. Hesitant fuzzy sets was used to handle such situations in which experts hesitate between several possible membership values to assess an alternative. In this paper, the concept of intuitionistic hesitant fuzzy set is introduced to provide computational basis to manage the situations in which experts assess an alternative in possible membership values and non-membership values. Distance measure is defined between any two intuitionistic hesitant fuzzy elements. Fuzzy technique for order preference by similarity to ideal solution is developed for intuitionistic hesitant fuzzy set to solve multi-criteria decision making problem in group decision environment. An example is given to illustrate this technique.

• Wind and Structures
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• v.36 no.2
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• pp.75-90
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• 2023

Turbulent wind flow over hilly terrains has been extensively investigated in the scientific literature and main findings have been included in technical standards. In particular, turbulent wind flow over nominally two-dimensional hills is often adopted as a benchmark to investigate wind turbine siting, estimate wind loading, and dispersion of particles transported by the wind, such as atmospheric pollutants, wind-driven rain, windblown snow. Windblown sand transport affects human-built structures and natural ecosystems in sandy desert and coastal regions, such as transport infrastructures and coastal sand dunes. Windblown sand transport taking place around any kind of obstacle is rarely in equilibrium conditions. As a result, the modelling of windblown sand transport over complex orographies is fundamental, even if seldomly investigated. In this study, the authors present a wind-sand tunnel test campaign carried out on a nominally two-dimensional sinusoidal hill. A first test is carried out on a flat sand fetch without any obstacle to assess sand transport in open field conditions. Then, a second test is carried out on the hill model to assess the sand flux overcoming the hill and the morphodynamic evolution of the sand sedimenting over its upwind slope. Finally, obtained results are condensed into a dimensionless parameter describing its sedimentation capability and compared with values resulting from other nominally two-dimensional obstacles from the literature.

• Wind and Structures
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• v.8 no.2
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• pp.79-88
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• 2005

This paper deals with a unified way for calculating vortex-induced vibrations (Aeolian vibrations in transmission line parlance) of undamped single overhead conductors. The main objective of the paper is to identify reduced parameters which would unify the predicted vibration response to the largest possible extent. This is actually done by means of a simple mathematical transformation resulting, for a given terrain (associated to a given wind turbulence intensity), into a single, unified response curve that is applicable to any single multi-layered aluminium conductor. In order to further validate the above process, the predicted, unified response curve is compared with measured response curves drawn from tests run on a full-scale test line using several aluminium-conductor-steel-reinforced (ACSR), all-alloy-aluminium-conductor (AAAC) and aluminium-conductor-alloy-reinforced (ACAR) conductors strung at different tensions. On account of the expected scatter in the results from such field tests, the agreement is shown to be good. The final results are expressed by means of only four different curves pertaining to four different terrain characteristics. These curves may then be used to assess the vibration response of any undamped single, multi-layer aluminium conductor of any diameter, strung at any practical tension.

• 한국신재생에너지학회:학술대회논문집
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• 2010.11a
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• pp.191-191
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• 2010

As many researchers want to predict or assess more about wind condition and wind power generation, CFD(Computational Fluid Dynamics) analysis method is very good way to do predict or assess wind condition and power generation. But CFD analysis is needed much knowledge of aerodynamics and physical fluid theory. In this paper, Auto-Wind CFD analysis program will be introduced. User does not need specific knowledge of CFD or fluid theory. This program just needs topographical data and wind data for initial condition. Then all of process is running automatically without any order of user. And this program gives for user to select and set initial condition for advanced solving CFD. At the last procedure of solving, Auto-Wind program shows analysis of topography and wind condition of target area. Moreover, Auto-Wind can predict wind power generation with calculation in the program. This Auto-Wind analysis program will be good tool for many wind power researchers in real field.

• Journal of the Korean Society of Safety
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• v.23 no.4
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• pp.72-78
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• 2008

In any form of construction work, it is essential that accidents be prevented at every stage from foundation preparation to build completion. For this, it is necessary to use models that can assess risk and provide instruction for safe work processes so that the risk of accidents is reduced. Currently, however, very few models can perform these tasks. In this paper, we presents a model that assesses risk quantitatively by analyzing risk factors involved in stage of construction such as foundation work, erection work, structural work, equipment work, finishing work and etc work. The model performs assessment based on examples of accidents and by investing actual conditions during construction. In addition, we presents in this paper a safety management system was developed to assess risk during construction and to effectively train laborers.

• Earthquakes and Structures
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• v.6 no.3
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• pp.237-250
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• 2014

This paper experimentally investigates the seismic performance of RC columns retrofitted with Super Reinforcement with Flexibility (SRF), which is a polyester fiber reinforced polymer. A total of three specimens with a scale factor of 1/2 were constructed and tested in order to assess the structural behavior of the retrofitted RC columns. One specimen was a non-seismically designed column without any retrofit, while others were retrofitted with either one or two layers of the polyester belt with urethane as the adhesive. Static cyclic testing with a constant axial load was conducted to assess the seismic performance of the retrofitted RC columns. It is concluded that the SRF retrofitting method increases the strength and ductility of the RC columns and can also impact on the failure mode of the columns.