• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제19권2호
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• pp.112-119
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• 2008

Objectives : This study was conducted to examine whether there are qualitative differences in attention problem among children with various psychiatric disorders, including attention-deficit hyperactivity disorder (ADHD), depressive disorder, anxiety disorder, and tic disorder using clinical ADHD diagnostic system (ADS) T-scores. Methods : The subjects were 794 outpatient children aged from 5 to 15 years, including 540 children with ADHD, 95 children with depressive disorder, 86 children with anxiety disorder, and 73 children with tic disorder. Clinical T-scores on the ADS were calculated using the mean and standard deviations of four ADS variables for the ADHD group. Results : All four groups had T-scores on the ADS in the abnormal range. However, when comparing the clinical T-scores, the children with depressive and anxiety disorders performed better than the children with ADHD. We also found that although the four groups seemed to be similar in terms of clinical T-scores for omission and commission errors, there were significant differences in clinical T-scores for reaction time and the standard deviation of response time (RT) between the ADHD and other groups. Conclusions : We concluded that inattention and impulsivity might not be specific only to ADHD and that the clinical T-scores of RT and standard deviation of RT on the ADS could be used to discriminate between ADHD and other clinical groups.

• 대한한방내과학회지
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• 제38권5호
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• pp.650-657
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• 2017

Objective: This study was performed to report the effect of traditional Korean medicine as a treatment for laryngopharyngeal reflux (LPR) combined with depressive and anxiety disorder. Methods: We treated this patient with traditional Korean medicine and measured symptom severity using the reflux symptom index (RSI), Beck depression inventory (BDI), and Beck anxiety inventory (BAI). Results: After 3 weeks of treatment, most symptoms had decreased. The RSI score dropped from 21 to 8, BDI from 27 to 14, and BAI from 29 to 15. Conclusions: Traditional Korean medicine may be effective as a treatment for LPR combined with depressive and anxiety disorder, and a correlation may exist between LPR and psychological factors. However, more rigorous studies are required to identify exactly what treatment is most efficient for relieving LPR combined with depressive and anxiety disorder and whether LPR and psychological factors are clearly correlated.

• 대한불안의학회지
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• 제10권2호
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• pp.176-181
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• 2014

Objective : Despite high prevalence and effective treatments of panic disorder, lots of patients are not properly treated due to lack of awareness of the disorder. This study summarizes and presents the results from Public Awareness Survey of Panic Disorder during the Mental Health Exposition held in Seoul in April, 2014. Methods : A total of 401 participants who visited the booth of the Korean Academy of Anxiety Disorder agreed and completed the survey. The questionnaires comprised of three sections; first, after given a case of patient with panic disorder, participants were asked to choose a diagnosis and treatment options. Second, participants were asked to differentiate the symptoms of panic disorder from those of other mental disorders and answer where they acquired the knowledge of the disorder. Third, visual analogue scales were used to get more detailed information for several issues about panic disorder. The incidence and ratio for each question were provided and compared. Results : Among the participants, 78% reported a patient within the case need treatment, and 30% accurately recognized it was panic disorder. As for treatment needed, 40% selected psychotherapy by psychiatrists, 28% chose counseling by psychologist, 23% said that they can overcome it by self-care. Only 2% of participants selected the pharmacotherapy as treatment needed. Approximately 40% of participants have encountered information about the disorder from gossips of celebrities, 32% from mass-media, and merely 6% from medical professionals. About 80% of participants could discriminate the symptom of panic disorder from those of depression, schizophrenia, or generalized anxiety disorder. Conclusion : Our results suggest that substantial proportions of participants have the awareness of panic disorder, while as for treatment they were strongly biased against pharmacologic treatments. Most of their source of the awareness was not relied upon professional information. Efforts for giving correct information and increasing public awareness of panic disorder are needed to bridge a gap between professionals and general public.

• 대한불안의학회지
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• 제6권1호
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• pp.10-16
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• 2010

Researchers consider obsessive-compulsive disorder (OCD) to be an anxiety disorder, but it often shows comorbidity with other disorders in the affective spectrum. Epidemiological and clinical studies have shown a strong association between OCD and mood disorders. In addition, some reports show the patients with OCD have attentional-processing impairments regarding emotional information. However, research has not revealed the exact nature and degree to which OCD constitutes an affective problem. In this review, we discuss the affective aspects of OCD and the relationship between OCD and mood disorders.

• 수면정신생리
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• 제26권2호
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• pp.104-110
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• 2019

목 적 : 본 연구의 목적은 불면을 주소로 대학병원 정신건강의학과 외래를 내원한 환자들 중 불면 장애를 단독으로 진단 받은 환자 군과 불면 장애와 함께 우울 장애 또는 불안 장애를 진단 받은 환자 군들의 인구학적 특성 및 State-Trait Anxiety Inventory (STAI) 결과 차이를 살펴봄으로써, 그들의 특징들을 조사하는 것이다. 방 법 : 2006년 1월 1일부터 2018년 12월 31일까지 불면을 주소로 대학병원 정신건강의학과 외래를 내원한 환자들 중 DSM-IV-TR의 불면 장애 진단기준을 만족하는 것과 동시에 STAI를 시행했던 환자들의 기록들을 후향적으로 분석하였다. 불면 장애를 진단 받은 환자들은 주로 해당 질환만 진단받은 군, 불안 장애를 같이 진단 받은 군, 우울 장애를 함께 진단 받은 군으로 분류되었는데, 각 군들 간의 인구학적 특성 및 STAI 결과에 대하여 비교 분석하고자 하였다. 결 과 : 해당기간 동안 불면을 주소로 정신건강의학과를 방문하여 불면 장애를 진단받고, STAI를 시행한 환자는 총 329명이고, 그 중 99명은 우울 장애를, 61명은 불안 장애를 동시에 진단받았다. 세 환자 군들 사이에서 나이, 성비와 같은 인구학적 특성의 차이는 없었으며, 공통적으로 50대부터 70대의 환자들의 비율이 불면 장애만 진단받은 환자 군에서는 71.8% 우울장애 또는 불안장애를 함께 진단받은 군들은 각각 77.1%, 73.8%로 높았다. STAI-I의 평균 점수는 불면 장애와 불안장애를 함께 진단받은 군은 51.85 ± 10.16, 우울장애를 함께 진단받은 군은 54.18 ± 10.32로 불면 장애를 단독으로 진단 받은 환자 군의 평균인 44.55 ± 8.89 보다 높았으나, 불안 장애 또는 우울 장애를 함께 진단 받은 군들 사이의 차이는 통계적으로 유의하지 않았다. 이와 유사하게 STAI-II의 평균점수는 불면 장애와 불안 장애를 함께 진단받은 군은 49.98 ± 8.31, 우울 장애를 함께 진단받은 군은 53.19 ± 10.13으로 불면 장애만을 진단받은 환자들의 평균(42.71 ± 8.84) 보다 높았으나, 두 군들 간의 차이는 통계적으로 유의하지 않았다. 결 론 : 불면을 주소로 방문한 환자들 중 불면 장애 만을 진단받은 환자 군과 우울 장애 또는 불안 장애를 함께 진단 받은 환자 군들의 인구학적 특성은 유사하지만, STAI-I과 STAI-II 평균은 낮았다. 추후 이를 기반으로 동반질환 등을 포함한 다른 인구학적 특성을 반영하고, 더 많은 수의 불면장애 환자들을 대상으로 STAI-I와 II의 차이를 비교하는 것이 필요할 것 이다.

• 생물정신의학
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• 제16권1호
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• pp.37-45
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• 2009

Objectives : It is reported that panic disorder is frequently comorbid with other psychiatric illnesses. The aim of this study was to investigate differences of psychiatric comorbidity according to age of onset of panic disorder. Methods : Three hundred-two patients participated in the study. All the patients were evaluated by clinical instruments for the assessment the presence of other comorbid psychiatric disorders and various clinical features; Korean version of Mini International Neuropsychiatric Interview, Self-report questionnaires(Beck Anxiety Inventory, Beck Depression Inventory, Anxiety Sensitivity Index and State-Trait Anxiety Inventory) and clinical rating scale (Hamilton Anxiety Scale, Hamilton Depression Scale and Global Assessment of Functional score). Chi-square test was used to determine the difference between early onset and late onset panic disorder. Results : Forty percent of panic patients were found to have at least one comorbid psychiatric diagnosis. There were no differences among the groups divided by number of comorbidity in sex, agoraphobia comorbidity, duration of panic disorder, except onset age of panic disorder. Early onset group had more comorbidy with social phobia, agoraphobia, PTSD. We also found that Early onset panic disorder patients were more likely to experience derealization, nausea, parethesia than late onset panic disorder patients. Conclusion : The results of our study are in keeping with previous data from other parts of the world. Our finding suggest that earier onset of panic disorder related to more psychiatric comorbidity.

• 동의신경정신과학회지
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• 제25권4호
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• pp.319-332
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• 2014

Objectives: This study was conducted to evaluate the clinical effects of group therapy for Panic disorder patients based on Mindfulness & Li-Gyeung-Byun-Qi therapy. Methods: The FFMQ, BDI, STAI, STAXI, Panic attack, Anticipatory anxiety and subjective improvement of three Panic disorder patients were compared pre- and post-treatment when given Mindfulness & Li-Gyeung-Byun-Qi therapy. Results: 1) After the patient in case 1 underwent 5 weeks of group therapy for Panic disorder, the Mindfulness meditation score was slightly improved, anxiety and depression were significantly decreased, and expression of anger was also improved. In addition, the Panic attack and Anticipatory anxiety became more stable in the objective evaluation, while 'Extreme improvement' was shown in the subjective evaluation. 2) After the patients in case 2 and 3 underwent 5 weeks of group therapy for Panic disorder, Mindfulness meditation scores were slightly improved, anxiety and depression were significantly decreased, and expression of anger was also improved. In addition, the Panic attack and Anticipatory anxiety became more stable in the objective evaluation, while 'Moderate improvements' were shown in the subjective evaluation. Conclusions: As per the results in these cases, it was shown that group therapy for Panic disorder utilizing Mindfulness & Li-Gyeung-Byun-Qi therapy was effective to maintain meditation and control the emotions of anxiety, depression, anger and so on. Therefore, it was considered that expansion of clinical utilization through the standardization of a group therapy program for Panic disorder is needed. Furthermore, it was also considered that a comparative study of the effects of previous cognitive programs for Panic disorder according to the objectified and standardized manual is needed in the future.

• 동의신경정신과학회지
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• 제9권2호
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• pp.161-169
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• 1998

A clinical analysis was carried out for 19 patients who was treated in Dept. of Neuropsychiatry of Taejon Oriental Medicine Hospital from I aug. 1997 to 31 Jul. 1998 and was ruled out as anxiety disorder. The results were summarized as follows. 1. In the distribution of the sex, ratio between female and male was 1:2.8, distribution of the age was even each age, and the primary motive of the onset were psychological trauma, question of money, discord of a household. 2. As for the duration in disease, the duration from a week to a month had a majority of all, and the most duration of the addmission-treatment was a week. 3. The most common symptom were palpitation ·anxiety, headache·dizziness, chest discomfort, the cases of generalized anxiety disorder and atypical anxiety disorder was a large number. 4. In the aromatherapy of absorptive method, the sort of many used essential oil were Lavenda and Rosewood, in the massage, that were Peppermint and Rosemary. 5. The most used recipes were BUNSIMKIYEM(分心氣飮) HACHULBOSIMTANG(夏朮補心湯), CHUNGGANSOYOSAN(淸肝逍遙散), BANHABAEKCHUCHUNMATANG(半夏白朮天麻湯), CUIBIONDAMTANG(歸脾溫膽湯) etc. 6. In the judgement of efficacy, 9 cases showed good efficacy, 9 cases showed no change, 1 case showed excellent efficacy.

• 동의신경정신과학회지
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• 제33권3호
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• pp.317-327
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• 2022

Objectives: To examine clinical effects of Korean medical treatment on depressive disorder. Methods: Medical records of 102 patients diagnosed with depressive disorder who were treated with Korean medical treatment (herbal-medication, acupuncture, Korean psychotherapy) for at least 12 weeks and measured psychological scales (Beck Depression Inventory-II (BDI-II), State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and State-Trait Anger Expression Inventory (STAXI)) every 4 weeks were analyzed. Results: After 12 weeks of treatment, BDI-II, STAI-X-1/2, BAI, and STAXI-S/T all decreased statistically significantly. STAI-X-1 and BAI were significantly decreased throughout the treatment interval (comparisons every 4 weeks). The other four scales decreased significantly from 0 to 4 weeks and from 8 to 12 weeks. Conclusions: Treatment for depressive disorder with Korean Medicine was effective not only in improving overall symptoms of depressed patients, but also in improving accompanying anxiety, anger, and physical symptoms. In addition, since all scores were gradually decreased, continuous treatment would be important.

• 대한불안의학회지
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• 제1권1호
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• pp.25-30
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• 2005

In the 40 years since the first benzodiazepine was brought into clinical use there has been a substantial growth in understanding the molecular basis of action of these drugs and the role of their receptors in anxiety disorders. Benzodiazepine receptors are present throughout the brain with the highest concentration in cortex, and it potentiate and prolong the synaptic action of the inhibitory neurotransmitter GABA. Central benzodiazepine receptors and $GABA_A$ receptors are part of the same macromolecular complex. Abnormalities of these $GABA_A$-benzodiazepine receptors as a result of drug challenge tests and neuroimaging studies may underlie some anxiety disorders. The role of $GABA_A$-benzodiazepine receptors in the action of benzodiazepine and as a factor in anxiety disorder, in both animal and humans including knock-out and knock in technique, may lead to new anxiolytics that have potentially significant therapeutic gains without unwanted side effects.