• Title/Summary/Keyword: Anti-crossing behavior

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Modal Analysis of Point and Discretized Continuous Spectra for Metal-Insulator-Metal Waveguides in the Terahertz Region

  • Hur, Jun;Choo, Hosung;Park, Jong-Eon
    • Journal of Electrical Engineering and Technology
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    • v.13 no.4
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    • pp.1644-1654
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    • 2018
  • Eigenvalue distributions for a periodic metal-insulator-metal waveguide, classified into the point spectrum and the discretized continuous spectrum (DCS), are investigated as functions of frequencies, gap widths, and periods. Muller's method is suggested for solving exact eigenvalues, and we propose the scheme for finding proper initial values in the Muller's method by considering only ${\Re}e({\varepsilon}_r)$ in the dispersion equation. We then find that anti-crossing behavior, repulsive effect between the point spectrum and the DCS, becomes stronger when the real parts of the roots in the point spectrum have smaller values. Finally, we examine the transmittances of a single subwavelength slit for real metals using the mode matching technique. The transmittances in real metals similarly follow those of the perfect electric conductor (PEC) at low frequencies, while the patterns at higher frequencies begin to differ from the PEC.

The Anti-depressive Effect of Samul-tanggahyangbuja on Chronic Mild Stress in Ovariectomized Rats (만성 스트레스 모델에서 사물탕가향부자의 항우울 효과)

  • Jeong, Ji-Hye;Choi, Chang-Min;Seo, Yun-Jung;Cho, Han-Baek;Kim, Song-Baek
    • The Journal of Korean Obstetrics and Gynecology
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    • v.26 no.4
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    • pp.30-47
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    • 2013
  • Objectives: The purpose of the present study is to investigate anti-depressive effects of Samul-tanggahyangbuja (SGH) on ovariectomized and chronic mild stress (CMS) induced rats. Methods: Ovariectomized rats were exposed to CMS for 4 weeks. Changes of depression behavior were tested by using sucrose intake test (SIT), elevated plus maze (EPM), forced swimming test (FST) and Morris water maze test (MWMT) in rats until being orally medicated with SGH (100 or 400 mg/kg/day). In addition, the serum levels of corticosterone (CORT), IL-4, IL-$1{\beta}$ and changes of 5-HT in the brain were measured. Results: 1. SGH 400 mg/kg treated group (SGH 400) significantly increased amount of sucrose intake compared with the control group (p<0.05). 2. SGH 100 mg/kg treated group (SGH 100) and SGH 400 significantly increased the time spent in the open arms of the EPM compared with the control group (p<0.01). SGH 400 also significantly increased the number of crossing of the open and closed arms compared with the control group (p<0.05). 3. SGH significantly shortened the immobility time in FST compared with the control group (SGH 100 p<0.05, SGH 400 p<0.01). 4. SGH significantly increased performance of acquisition trials compared with the control group (p<0.05, on day 4, 5 of SGH 100 and 400). SGH 400 also significantly increased performance of retention trials compared with the control group (p<0.05). 5. The serum levels of corticosterone and IL-4 were not significantly different among the groups. There were no changes on the serum levels of corticosterone, IL-$1{\beta}$ and IL-4 after administration with SGH. 6. SGH 400 significantly increased the level of 5-HT in the hippocampus compared with the control group (p<0.05). SGH significantly increased the levels of 5-HT in the hypothalamus compared with the control group (SGH 100 p<0.05, SGH 400 p<0.01). Conclusions: These results suggest that SGH has the anti-depressive effect on ovariectomized rat and affect 5-HT system rather than hypothalamic-pituitary-adrenal (HPA) axis and immune system.

The Effect of Gyogam-dan on Depression and Immunity on Repeated Stress in Ovariectomized Rats (교감단이 우울행동과 면역기능에 미치는 효과)

  • Cheong, Hyun-Cheol;Kim, Song-Baek;Seo, Yun-Jung;Cho, Han-Baek;Choi, Chang-Min
    • The Journal of Korean Obstetrics and Gynecology
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    • v.26 no.3
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    • pp.18-32
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    • 2013
  • Objectives: In this research, the effect of Gyogam-dan (GGD) on depression and immunity were assessed in ovariectomized rats subjected to repetitive stress. GGD is the prescription consisting of Poria cocos and Cyperi Rhizoma. Methods: Ovariectomized rats were repeatedly stressed over a 2-week period. After GGD (100 or 400 mg/kg) were orally administered, Elevated Plus Maze (EPM) and forced swimming test (FST) were performed to evaluate depressive and anxiety response. As well, the change of corticosterone (CORT) and the change of interleukin-$1{\beta}$ (IL-$1{\beta}$) and interleukin-4 (IL-4) in blood serum and in brain were mesured. Results: 1. In the EPM, there were no statistically significant differences among the groups. 2. In the FST, immobility time significantly decreased in rats of each experiment group compared with the control group (p<0.01). 3. Serum CORT level were decreased in 400 mg GGD group (p<0.05). 4. On IL-$1{\beta}$ and IL-4 measurement in the serum and brain, there were not significant increase or decrease compared with the control group. Conclusions: These results suggest that GGD is effective to reduce depression-behavior in ovariectomized rats. However, GGD do not has significant efficacy to reduce anxiety-behavior in EPM test. Measurement of serum CORT level reveals significant decrease and it shows anti-depressant like effect. Results on immunity are not significant.