• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 추계학술대회 논문집 Vol.21
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• pp.378-379
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• 2008

Recently, composite hollow bushings have been increasingly employed mainly from the various characteristics. Composite bushings are superior to porcelain bushings in several respects, including lighter weight, better anti-pollution and anti-explosion properties, and easer manufacturing. Filament wound GRP tubes which have various winding angle were manufactured by using a filament winding machine. This paper will show some design issues and winding condition for composite bushing. And, results show that the winding condition of composite GRP tubes can be used to improved their bending strength and pressure, For bending and pressure tested, tubes with the hybrid winding pattern show higher strength than those of unit winding pattern. Also, the influence of absorption was evaluated through such as measurement of the dye penetration test and water diffusion test, also aspects of surface state using scanning electron microscopy.

• 한국군사과학기술학회지
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• 제16권3호
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• pp.382-389
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• 2013

In anti-jamming GPS receiver, adaptive signal processing techniques in which the radiation pattern of adaptive array antenna of elements may be adaptively changed used to reject interference, clutter, and jamming signals. In this paper, I describes adaptive signal processing technique using the sample matrix inversion(SMI) algorithm. This adaptive signal processing technique can be applied effectively to wideband/narrowband anti-jamming GPS receiver because it does not consider the satellite signal directions and GPS signal power level exists below the thermal noise. I also analyzed the effects of covariance matrix sample size and diagonal loading technique on the system performance of five-element circular array antenna. To attain near optimum performance, more samples required for calculation covariance matrix. Diagonal loading technique reduces the system nulling capability against low-power jamming signals, but this technique improves robustness of adaptive array antenna.

• 한국컴퓨터정보학회지
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• 제14권1호
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• pp.287-297
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• 2006

본 논문에서는 하드카피 문서에 대한 새로운 재생산 방지 기법을 제안한다. 일반 프린터로 일반 용지에 출력한 원본 하드카피를 칼라 복사기로 복사하거나 스캐너로 스캔하여 다시 출력할 경우 원본 하드카피에 포함된 복사방지 패턴에 특별한 문구 패턴이 나타나 복사본임을 육안으로 구분할 수 있는 기술이다. 이를 위하여 본 논문에서는 하프톤 셀과 스폿을 사용하여 병치 감법혼합으로 농도가 잘 조절된 칼라패턴을 생성한다. 본 논문에서 제안한 하드카피 복사 방지 기법은 기존의 방법에 비해 고해상도 복사 방지 기법으로 유용한 방법이다.

• 한국기후변화학회지
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• 제9권3호
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• pp.209-221
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• 2018

The characteristics of heat wave events in Seoul are analyzed using weather station data from Korea Meteorological Administration (KMA) and European Centre for Medium-Range Weather Forecast (ECMWF) ERA-Interim reanalysis data from 1979 to 2016. Heat waves are defined as events in the upper 10th percentile of the daily maximum temperatures. The associated synoptic weather patterns are then classified into six clusters through Self-Organizing Map (SOM) analysis for sea-level pressure anomalies in East Asia. Cluster 1 shows an anti-cyclonic circulation and weak troughs in southeast and west of Korea, respectively. This synoptic pattern leads to southeasterly winds that advect warm and moist air to the Korean Peninsula. Both clusters 2 and 3 are associated with southerly winds formed by an anti-cyclonic circulation over the east of Korea and cyclonic circulation over the west of Korea. Cluster 4 shows a stagnant weather pattern with weak winds and strong insolation. Clusters 5 and 6 are associated with F?hn wind resulting from an anti-cyclonic circulation in the north of the Korean Peninsula. In terms of long-term variations, event frequencies of clusters 4 and 5 show increasing and decreasing trends, respectively. However, other clusters do not show any long-term trends, indicating that the mechanisms that drive heat wave events in Seoul have remained constant over the last four decades.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3735-3742
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• 2013

Background: Cardamom (Elettaria cardamom), also known as "Queen of Spices", has been traditionally used as a culinary ingredient due to its pleasant aroma and taste. In addition to this role, studies on cardamom have demonstrated cancer chemopreventive potential in in vitro and in vivo systems. Nevertheless, the precise poly-pharmacological nature of naturally occurring chemo-preventive compounds in cardamom has still not been fully demystified. Methods:In this study, an effort has been made to identify the proapoptopic, anti-inflammatory, anti-proliferative, anti-invasive and anti-angiogenic targets of Cardamom's bioactive principles (eucalyptol, alpha-pinene, beta-pinene, d-limonene and geraniol) by employing a dual reverse virtual screening protocol. Experimentally proven target information of the bioactive principles was annotated from bioassay databases and compared with the virtually screened set of targets to evaluate the reliability of the computational identification. To study the molecular interaction pattern of the anti-tumor action, molecular docking simulation was performed with Auto Dock Pyrx. Interaction studies of binding pose of eucalyptol with Caspase 3 were conducted to obtain an insight into the interacting amino acids and their inter-molecular bondings. Results:A prioritized list of target proteins associated with multiple forms of cancer and ranked by their Fit Score (Pharm Mapper) and descending 3D score (Reverse Screen 3D) were obtained from the two independent inverse screening platforms. Molecular docking studies exploring the bioactive principle targeted action revealed that H- bonds and electrostatic interactions forms the chief contributing factor in inter-molecular interactions associated with anti-tumor activity. Eucalyptol binds to the Caspase 3 with a specific framework that is well-suited for nucleophilic attacks by polar residues inside the Caspase 3 catalytic site. Conclusion:This study revealed vital information about the poly-pharmacological anti-tumor mode-of-action of essential oils in cardamom. In addition, a probabilistic set of anti-tumor targets for cardamom was generated, which can be further confirmed by in vivo and in vitro experiments.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.6001-6005
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• 2013

Our aim was to explore anti-cell proliferative and anti-angiogenic potential of andrographolide by analyzing the expression pattern of cell proliferative (PCNA, Cyclin D1) and angiogenic (VEGF) markers during 7, 12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis. DMBA painting three times a week for 14 weeks in the buccal pouch of golden Syrian hamsters resulted in oral tumors which were histopathologically diagnosed as well differentiated squamous cell carcinoma. Immunohistochemical (PCNA, VEGF) and RT-PCR (Cyclin D1) studies revealed over expression of PCNA, VEGF and Cyclin D1 in the buccal mucosa of hamsters treated with DMBA alone. Oral administration of andrographolide at a dose of 50 mg/kg bw to hamsters treated with DMBA not only suppressed the histological abnormalities but also down regulated the expression of PCNA, VEGF and Cyclin D1. The results of the present study suggest that andrographolide suppressed tumor formation in the buccal mucosa of hamsters treated with DMBA through its anti-cell proliferative and anti-angiogenic potential.

• Biomolecules & Therapeutics
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• 제17권1호
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• pp.79-85
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• 2009

Polyphenolic compounds are reported to have various pharmacological activities such as anti-oxidative, anti-cancerous, anti-inflammatory and anti-aging effects. Although numerous papers explore their functional roles in many different cellular actions, not many studies handle their structural features in anti-inflammatory responses. In this study, therefore, we examined structural role of substituted transstilbenes in their NO inhibitory and NF-${\kappa}B$ suppressive activities. Of 10 compounds tested, 4 compounds (cinnamic acid, resveratrol, piceatannol and curcumin) displayed NO inhibitory activities in a dose-dependent manner. Similarly, these compounds blocked LPS-induced cytotoxicity of RAW264.7 cells. All NO inhibitory compounds also inhibited $I{\kappa}B{\alpha}$ phosphorylation, a hallmark for NF-${\kappa}B$ activation. However, these inhibitory compounds exhibited distinct suppressive pattern in tumor necrosis factor (TNF)-${\alpha}$- or phorbol-12-myristate-13-acetate (PMA)-induced NF-${\kappa}B$ and AP-1 activation. According to structure-activity relationship study, polarity and size of ring B seem to be important for diminishing NO production. Therefore, our data suggest that substituted trans-stilbenes can be developed as novel anti-inflammatory drug or further developed as lead compounds for another improvement.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2003년도 봄 학술발표논문집 Vol.30 No.1 (B)
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• pp.4-6
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• 2003

디자인 패턴과 안티 패턴의 원리는 혼합되어 사용되어진다. 디자인 패턴은 소프트웨어 품질에 대하여 공격적인 예방치료에 목적을 두며, 안티 패턴은 품질 이슈에 대하여 체계적인 진단을 수행하는 것이다. 품질에 대한 국제 표준으로는 ISO/IEC 9126, ISO/IEC 12119등이 있다. 최근에는 이러한 품질에 관련된 문제점들을 해결하기 위하여 디자인 패턴과 안티 패턴에 대한 연구가 활발히 이루어지고 있다. 본 논문에서는 현재 대표적으로 사용되어지는 디자인 패턴과 안티 패턴을 ISO/IEC 9126의 품질 특성별로 분류하고 이들간의 상호 연관성에 대하여 연구하였다.

• 인터넷정보학회논문지
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• 제14권4호
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• pp.25-33
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• 2013

RFID 시스템에서는 다중 태그가 동일한 주파수로 동시에 리더의 요청에 응답하기 때문에 발생하는 태그 충돌을 중재하는 절차가 필수적이다. 이 절차를 충돌 방지 알고리즘이라 하며 RFID 시스템에서 가장 핵심적인 기술이다. 본 논문에서는 다중 태그의 고속 식별을 위한 4-BPSA(4-Bit Pattern Slot Allocation) 알고리즘을 제안한다. 제안한 알고리즘은 슬롯을 사용하는 트리 기반의 알고리즘으로서 4비트 패턴에 따른 슬롯 할당 기법을 이용하여 정확한 예측을 통해 빠르고 효율적으로 태그를 식별한다. 알고리즘에 대한 수학적 성능 분석을 통해 worst-case에서 4-BPSA의 시간 복잡도가 O(n)이며 기존의 알고리즘에 비해 성능이 개선되었음을 보인다. 또한 MATLAB을 이용한 시뮬레이션 실험을 통한 알고리즘의 성능 평가 결과에 의거해 4-BPSA 알고리즘이 태그당 평균 0.7회의 질의를 수행하며 태그의 개수와 상관없이 안정적인 성능을 보이는 것을 검증하였다.

• Journal of Preventive Medicine and Public Health
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• 제25권2호
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• pp.172-179
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• 1992

The author investigated the zinc concentrations in sera of 110 methamphetaimine abusers (male 87, female 23) and of 41 healthy official workers(male 29, female 12) using inductively coupled plasma emission spectrometer. The serum zinc concentrations were analysed according to hepatitis C virus antibody(Anti HCV), hepatitis B surface antigen(HBsAg) and alanine aminotransferase(ALT) value in both groups. The analytical results were obtained as follows 1. The mean zinc concentration of MAP abuser group($298.5{\pm]246.9{\mu}g/100ml$) was 2.5 times higher than that of control group($118.8{\pm}25.4{\mu}g/100ml$). 2. The distributions of zinc concentration in both groups were skewed pattern. 3. The zinc concentrations were higher in Anti HCV-positive group and abnormal ALT value group than Anti HCV-negative group and normal ALT value group. But HBs-Ag positive group had lower zinc concentration than HBs-Ag negative group. 4. The number of anti HCV-positive subjects was increased and the zinc concentrations were decreasd in proportion to the abusing duration of MAP.