• 대한치과교정학회지
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• 제16권2호
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• pp.81-97
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• 1986

The purpose of this study was to investigate the factors which cause the differences in the percentage of anterior overbite in spite of normal molar relationship in terms of skeletal, dental and dentoalveolar relations. The models and cephalograms taken from 154 subjects, 89 of shallow overbite and 65 of deep overbite ranging from 18 to 29 years of age were studied and analyzed statistically. The results were as follows. 1. In determining the percentage of anterior overbite, the significant differences were higher in the dental and dentoalveolar factors than in the skeletal factors and were higher in the proportional and angular measurements than in linear measurements. 2. The factor which had the greatest influence on the percentage of anterior overbite was the proportional parts of the dental and dentoalveolar heights. 3. The most influencing factor which determined the percentage of anterior overbite was the SN-MP angle among the skeletal factors.

• 디자인학연구
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• 제13권
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• pp.45-53
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• 1996

80년대의 거품경제 붕괴 후로는 가격, 용도, 품질, 실질 성 등 상품 기본가치를 중시하는 성숙된 소비사회로 전환될 수 있는 가치를 상품이 실현하고 있는 가이며, 딸서 기본에 충실하고 합리적인 차별화를 제시하는 등 소비자가 자신의 실생활에 있어서 중요하게 생각하고 있는 가치관과 조화를 이루는 상품성이다. 이러한 조건 속에서 소비자 수요의 단순한 발견에 의해 디자인 개념을 설정하는 것을 뛰어 넘어 소비자의 다양한 수요를 이끌어 갈 수 있고 기업의 시장 우위확보를 위한 경쟁력 제고 및 정체성 정립을 위한 방법의 하나로 디자인 인자 지향적 프로세스(factor oriented process)를 기초로 한 다원적 프로세스(multi-sequential process)를 제안한다. 이 인자 지향적 프로세스는 프로세스 내부의 요인 분석(分析) 및 특히 이들의 합성(合成)을 중시하여 이에 의해 새로운 해결안을 그 특성으로 하고 디자인 개발에 합리적인 근거를 제시하도록 한다. 이는 합성과정이란 분류된 인자의 특성에 의해 인자들을 체계적으로 조합하는 과정에 내재하는 제한 요소 사이의 상관관계를 분석하여 우위 인자(dominant factor)를 발견하고 이에 의해 가능한 몇 가지 코드를 만들어 디자인 개념의 방향을 제시하게 되어 디자인 모체를 만드는 과정이다. 다원적 디자인 프로세스란 폭 넓은 접근 방법으로 안으로는 제품 내에 존재하는 우위 인자의 규명에 의한 차별화된 대안들을 찾아내고 밖으로는 관련제품과의 연계성(連繫性)까지 고려한 선행 인자(anterior factor-다 가치 적 기준으로 디자인 방향을 결정해 주는 방향인자)를 찾아내 디자인 방향의 당위적 결정을 유도하는 디자인 프로세스이다.

• 한국의류학회지
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• 제26권1호
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• pp.15-26
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• 2002

The purpose of this study was to classier the somatotype of late middle-aged women and to analyze the characteristics of each somatotype. The subjects were 337 late middle-aged women and their age range os from 45 to 59 fears old. Data were collected through anthropometry and photometry and analyzed by factor analysis, cluster analysis and discriminant analysis. The results were as follows; 1. The result of factor analysis indicated that 9 factors were extracted through factor analysis and those factors comprised 83.56 percent of total valiance. 2. Using factor scores, cluster analysis was carried out and the subject were classified into 4 cluster. Each cluster was classified as their body front and side view contour. Type 1 is tall, slim, and lower balk is flat on the side. Type 2 is standard and lean-back type on the side. Type 3 is standard height and weight, H type in front, and belly-protruded on the side. Type 4 is short, fat, and the side is hip-protruded. 3. According to the stepwise discriminant analysis, the 9 important items in classifying the somatotype of the late middle-aged women are as follows ; lower back tilt angle, hip depth(back) -back waist depth(back), bust depth(fore) - anterior waist depth(fore), jugular fossa point(fore), upper back tilt angle, burst breadth -waist breadth, right shoulder tilt, height of shoulder - height of anterior waist, abdomen breath. The correct classification rate for these items is as exact as 84.62%.

• 복식
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• 제58권6호
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• pp.35-41
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• 2008

The purposes of this study lied in the analysis and classification of neck-base circumference shapes of the women in their twenties, by the application of three-dimensional automatic measurement data of human body, and thereby in the understanding of neck-base circumference shapes by the classified type. The findings are as follows: 1. The comparison of three-dimensional human body measurement items relating to the neck-base circumference part of the women in their twenties indicated that the largest individual difference was found in cervicale-center-anterior neck radius than in other items. 2. The factor analysis, which was conducted to extract the factors constituting the neck-base circumference, showed the shape of cervicale(factor 1), the shape of section neck(factor 2), the thickness of neck(factor 3), the shape of anterior neck(factor 4), and the shape of side neck(factor 5). 3. The classification of the neck-base circumference shapes resulted in three types. Type 1 was the shape of a reverse triangle hanging forward, Type 2 was that of a circle, and Type 3 was that of an oval open to the sides.

• 대한족부족관절학회지
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• 제15권4호
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• pp.195-200
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• 2011

Impingement syndrome of the ankle is defined as painful mechanical limitation of full ankle movement secondary to osseous and/or soft tissue abnormality. These conditions occur more commonly in active people and athletes probably because recurrent subclinical injury is an important factor in development of the syndrome. Impingement syndromes of the ankle are categorized according to their anatomical site around the ankle joint. Anterolateral, anterior and posterior impingement has been extensively described in the orthopaedic literature. The purpose of this article is to review the clinical feature and management of anterior impingement syndrome of the ankle.

• 한국발생생물학회지:발생과생식
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• 제27권4호
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• pp.221-226
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• 2023

A stem cell niche provides an environment that governs stem cell maintenance and division. Thus, the development of a proper niche is of prime importance to stem cell behaviors. Mechanisms of niche development are beginning to be revealed in the Drosophila male gonad. Niche cells are initially dispersed throughout the gonad, then assemble at its apical tip through the anterior migration of posteriorly located niche cells. The molecular mechanisms of this migration and assembly are still poorly understood. Here we show evidence suggesting that Lin28, an RNA-binding protein and regulator of let7 genesis, might be an intrinsic factor for the anterior migration of niche cells. We found that a dispersed, ectopic niche, a phenotype observed with anterior migration defects, occurs in lin28 mutant gonads. This phenotype is rescued by expression of lin28 in the niche cells. These findings suggest that Lin28 might be required for the anterior migration of niche cells.

• Clinics in Shoulder and Elbow
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• 제18권1호
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• pp.1-1
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• 2015

• 대한치과보철학회지
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• 제57권4호
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• pp.467-474
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• 2019

최근 들어 치아의 심미적인 개선을 위해 전치부 보철 치료를 하는 경우가 많다. 하지만 전치부 심미 보철치료이후 환자가 발음, 저작 등 기능적으로 불만족스럽게 생각하는 경우가 종종 있다. 전치부는 심미적으로 중요할 뿐만 아니라 교합과 관련하여서도 중심위 다음으로 중요한 전방유도가 성립되는 부분으로, 잘못된 전방유도 설정으로 인해 구치부의 교합간섭을 초래할 수 있다. 또한 새롭게 설정된 전치부 보철물의 전방유도가 환자의 기능로(envelope of function)과 조화를 이루지 않을 시 환자가 불편감을 나타낼 수 있다. 본 증례는 전치부 심미 보철 이후 부정확한 발음 및 안정적인 접촉이 없어서 불안정한 교합, 전반적인 불편감을 호소하는 환자에서 체계적인 진단과 치료과정을 통해 보철물을 재수복하여 환자와 술자 모두에게서 심미적으로, 그리고 기능적으로 만족스러운 결과를 얻었기에 보고하는 바이다.

• Clinical and Experimental Reproductive Medicine
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• 제23권3호
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• pp.269-275
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• 1996

Biosynthesis and secretion of anterior pituitary hormones are under the control of specific hypothalamic stimulatory and inhibitory factors. Among them, Growth Hormone Releasing Hormone (GHRH) is the major stimulator of pituitary somatotrophs activating GH gene expression and secretion. Human GHRH is a polypeptide of 44 amino acids initially isolated from pancreatic tumors, and the gene for the hypothalamic form of GHRH is organized into 5 exons spanning over 10 kilobases (kb) on genomic DNA and encodes a messenger RNA of 700-750 nucleotides. Several neuropeptides classically associated with the hypothalamus have been found in the extrahypothalamic regions, suggesting the existence of novel sources, targets and functions. GHRH-like immunoreactivity has been found in several peripheral sites, including placenta, testis, and ovary, indicating that GHRH may also have regulatory roles in peripheral reproductive organs. Furthermore, higher molecular weight forms of the GHRH transcripts were identified from these organs (1.75 kb in testis; 1.75 and >3 kb in ovary). These tissue-specific expression of GHRH gene suggest the existence of unique regulatory mechanism of GHRH expression and function in these organs. In fact, placenta-specific and testis-specific promoters for GHRH transcripts which are located in about 10 kb upstream region of hypothalamic promoter were reported. The use of unique promoters in extrahypothalamic sites could be refered in a different control of GHRH gene and different functions of the translated products in these tissues. Somatotrophs and lactotrophs have been thought to be derived from a common bipotential progenitor, the somatolactotrophs, which give origins to either phenotypes. Although the precise mechanism responsible for the lactotroph differentiation in the anterior pituitary gland has not been yet clalified, there are several candidators for the generation of lactotrophs. In human, the presence of GHRH peptides with different size from authentic hypothalamic form in the normal anterior pituitary and several types of adenoma were demonstrated. Recently our group found the existence of immunoreactive GHRH and its transcript from the normal rat anterior pituitary (gonadotroph> somatotroph> lactotroph), and the GHRH treatment evoked the increased proliferation rate of anterior pituitary cells in vitro. The transgenic mouse models clearly shown that GHRH or NGF overexpression by anterior pituitary cells induced development of pituitary hyperplasia and adenomas particularly GH-oma and prolactinoma. Taken together, we hypothesize that the pituitary GHRH could serve not only as a modulator of hormone secretion but as a paracrine or autocrine regulator of anterior pituitary cell proliferation and differentiation. Interestingly enough, the expression of Pit-1 homeobox gene (the POU class transcription factor) was confined to somatotrophs, lactotrophs and somatolactotrophs in which GHRH receptors are expressed commonly. Concerning the mechanism of somatolactotroph and lactotroph differentiation in the anterior pituitary, we have focused following two possibilities; (1) changes in the relative levels or interactions of both hypothalamic and intrapituitary factors such as dopamine, VIP, somatostatin, NGF and GHRH; (2) alterations of GHRH-GHRH receptor signaling and Pit-1 activity may be the cause of lactotroph differentiation or pituitary hyperplasia and adenoma formation. Extensive further studies will be necessary to solve these complicated questions.

• 대한치과교정학회지
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• 제6권1호
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• pp.65-69
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• 1976

A patient (Hellman dental age IIIA) who had anterior cross bite due to functional factor was treated with activator. Following results were obtained: 1) Anterior cross bite was crorrected 3 months after the initial application of the appliance. 2) Comparing pretreatment records with posttreatment, the main effects were labioversion of upper incisors, increase of upper arch length and downward-backward rotation of the mandible. 3) There was no damage on teeth and periodontal tissues and the patient had normal occlusion 1 year after the treatment.