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Endotoxin-induced inflammation disturbs melatonin secretion in ewe

  • Herman, Andrzej Przemyslaw;Wojtulewicz, Karolina;Bochenek, Joanna;Krawczynska, Agata;Antushevich, Hanna;Pawlina, Bartosz;Zielinska-Gorska, Marlena;Herman, Anna;Romanowicz, Katarzyna;Tomaszewska-Zaremba, Dorota
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.12
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    • pp.1784-1795
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    • 2017
  • Objective: The study examined the effect of intravenous administration of bacterial endotoxin-lipopolysaccharide (LPS) -on the nocturnal secretion of melatonin and on the expression of enzymes of the melatonin biosynthetic pathway in the pineal gland of ewes, taking into account two different photoperiodic conditions: short-night (SN; n = 12) and long-night (LN; n = 12). Methods: In both experiments, animals (n = 12) were randomly divided into two groups: control (n = 6) and LPS-treated (n = 6) one. Two hours after sunset, animals received an injection of LPS or saline. Blood samples were collected starting one hour after sunset and continuing for 3 hours after the treatment. The ewes were euthanized 3 hours after LPS/saline treatment. The concentration of hormones in plasma was assayed by radioimmunoassay. In the pineal gland, the content of serotonin and its metabolite was determined by HPLC; whereas the expression of examined genes and protein was assayed using real-time polymerase chain reaction and Western Blot, respectively. Results: Endotoxin administration lowered (p<0.05) levels of circulating melatonin in animals from LN photoperiod only during the first hour after treatment, while in ewes from SN photoperiod only in the third hour after the injection. Inflammation more substantially suppressed biosynthesis of melatonin in ewes from SN photoperiod, which were also characterised by lower (p<0.05) cortisol concentrations after LPS treatment compared with animals from LN photoperiod. In the pineal gland of ewes subjected to SN photoperiod, LPS reduced (p<0.05) serotonin content and the expression of melatonin biosynthetic pathway enzymes, such as tryptophan hydroxylase and arylalkylamine-N-acetyltransferase. Pineal activity may be disturbed by circulating LPS and proinflammatory cytokines because the expression of mRNAs encoding their corresponding receptors was determined in this gland. Conclusion: The present study showed that peripheral inflammation reduces the secretion of melatonin, but this effect may be influenced by the photoperiod.

Ship Positioning Using Multi-Sensory Data for a UAV Based Marine Surveillance (무인항공기 기반 해양 감시를 위한 멀티센서 데이터를 활용한 선박 위치 결정)

  • Ryu, Hyoungseok;Klimkowska, Anna Maria;Choi, Kyoungah;Lee, Impyeong
    • Korean Journal of Remote Sensing
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    • v.34 no.2_2
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    • pp.393-406
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    • 2018
  • Every year in the ocean, various accidents occur frequently and illegal fishing is rampant. Moreover, their size and frequency are also increasing. In order to reduce losses of life or property caused by these, it is necessary to have a means to perform remote monitoring quickly. As an effective platform of such monitoring means, an Unmanned Aerial Vehicle (UAV) is receiving the spotlight. In these situations where marine accidents or illegal fishing occur, main targets of monitoring are ships. In this study, we propose a UAV based ship monitoring system and suggest a method of determining ship positions using UAV multi-sensory data. In the proposed method, firstly, the position and attitude of individual images are determined by using the pre-performed system calibration results and GPS/INS data obtained at the time when images were acquired. In addition, after the ship being detected automatically or semi-automatically from the individual images, the absolute coordinates of the detected ships are determined. The proposed method was applied to actual data measured at 200 m, 350 m, and 500 m altitude, the ship position can be determined with accuracy of 4.068 m, 8.916 m, and 13.734 m, respectively. According to the minimum standard of a hydrographical survey, the ship positioning results of 200 m and 350 m data satisfy grade S and the results of 500 m data do grade 1a, where the accuracy is required for positioning the coastline and topography less significant to navigation order. Therefore, it is expected that the proposed method can be effectively used for various purposes of marine monitoring or surveying.

Standard Clinical Procedure(Critical Pathway) on Dental Conscious Sedation for the Disabled Children (장애아동 진정치료에 대한 표준진료지침의 개발)

  • Kim, Minsu;Bae, Youngeun;Kim, Jiyeon;Jo, Anna;Yoon, Hyunseo;Song, Eunju;Jeong, Taesung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.42 no.3
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    • pp.226-232
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    • 2015
  • Critical pathway (CP) defines the optimal care process, sequencing and timing of intervention by multidisciplinary health care teams for a particular diagnosis and procedure. The aim of the study was to evaluate the clinical usefulness and the satisfaction of patients and dental staff after implementation of a critical pathway for the dental treatment of disabled children and adolescents under conscious sedation. Thirty patients are divided in two groups (Pre-CP and CP) at the department of Pediatric Dentistry of Pusan National University Dental Hospital. The satisfaction levels of patients/guardians and the staff members were collected by survey questionnaire. The parents' satisfaction was significantly improved after the implementation of CP. Also, medical/dental staff members were highly satisfied with its usefulness. The application of a critical pathway for disabled children and adolescents might be useful and improve the satisfaction of the parents and medical/dental staff members.

The evaluation of electrical properties for $LiNi_xMn_{2-x}O_4$ Nano powders by Ultra sonic pyrolysis (초음파 분무연소법에 의한 $LiNi_xMn_{2-x}O_4$ 분말의 전기적 특성 평가)

  • Oh, Hyo-Jin;Lee, Nam-Hee;Yoon, Cho-Rong;Czoska, Anna;Nam, Sang-Chul;Park, Kyeong-Soon;Lee, Nae-Sung;Kim, Sun-Jae
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.05a
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    • pp.113-116
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    • 2006
  • 자발착화 연소반응법 (Glycine Nitrate Process)을 응용한 초음파분무열분해장치를 이용하여 이차전지의 양극재료인 Ni치환형 $LiMn_2O-4$ 분말을 합성하였고, 각각의 하소온도에 따른 분말의 특성을 평가하였다. 전구용액은 산화제로 $Mn(NO_3)_2{\cdot}6H_20$EX>, $LiNO_3$, $Ni(NO_3)_2{\cdot}6H_20$를 사용하였고, 자발착화 에너지를 공급하기 위한 연료로는 glycine를 사용하였다. 분말의 결정상을 확인하기 위해 X-선 회절 시험을 시행하였으며, 각각의 조성별로 ICP측정결과 여러 조성들($LiNi_xNm_{2-x}O_4\;0{\leq}x{\leq]0.5$) 중 $LiNi_{0.3}Nm_{1.7}O_4$의 분말이 비교적 우수한 특성을 나타내었지만, 전기화학적 특성 평가 결과 이론용량값에 미치지 못하는 용량값을 나타내었다. 이것은 분말 합성 시 미량의 미 반응된 유기물들이 분말 표면에 피복되어 전기적 성질을 변화시키고 있기 때문임을 확인하였다. 이러한 특성을 개선하고자 추가적으로 하소 공정을 실시하여 전지의 성능를 평가 하였다. 분말의 미세구조와 형태, 크기, 전기 화학적 특성을 관찰하여 하소 전 후의 분말을 비교하였다.

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Constructing a Heterotopia of Migrant Space: 'Weekend Flat' of Filipino Migrant Care-givers in Tel Aviv, Israel (헤테로토피아로서의 이주 공간: 텔아비브 필리핀 노인돌봄노동자들의 '주말아파트'를 중심으로)

  • Lim, Anna
    • Journal of the Korean Geographical Society
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    • v.51 no.6
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    • pp.799-817
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    • 2016
  • This article aims to reveal the ways in which a "space of difference" is produced and interpret the space as a heterotopic space, drawing the case of Filipino elderly care-givers in Israel. The in-betweens and temporariness of the migrants'experiences in the Israeli society lead to the creation of a heterotopic space. Paying attention to their particular life rhythm as live-in care-givers, namely weekdays-workplace and weekend-flat, this article explores how the migrant care-givers build their own society through a variety of spatial practices and multiple social relations based on the flat. In making the flat a perfect form of a lifestyle for their own, the migrants inscribe their presence in the flat in unique ways for different purposes, in a way different to that which surrounds it. However, the structure of flat not only signifies the migrants' marginality but also reflects the challenging position. The flat has functions in relation to all other space that remains, even if such connection often creates effects of contrast and difference. In this light, the flat is not merely an alienated and circumscibed exotic migrant enclave but a heterotopic space which is dynamically constructed in relation to other sites in the wider societal order.

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An Intravenous Injection Simulator using Augmented Reality for Veterinary Education (증강현실 기술을 사용한 수의학 교육용 정맥 주사 훈련 시뮬레이터)

  • Lee, Jun;Seo, Anna;Kim, WonJong;Kim, Jee-In;Lee, SeungYeon;Eom, KiDong
    • Journal of the HCI Society of Korea
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    • v.7 no.2
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    • pp.25-34
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    • 2012
  • A veterinary student learns and experiences veterinary processes though experiments and practices using real animals. However, animal protection laws regulate animal experiments and restrict number of the experiments on laboratory animals, veterinary students would have less chances of the experiments and the practices for their veterinary training with real animals. This paper proposes a simulator for veterinary education based on augmented reality (AR). We selected an intravenous injection procedure for the simulation because the injection procedure is the most frequently used procedure during veterinary training and the most difficult stage for beginning veterinary students. The proposed AR simulator provides with a tangible prop, of which shape looks like a leg of a real dog. It also has a injection simulator, which receives user's input and sends force feedbacks to indicate results of the injection simulation. We developed a WorkBench type AR system with an LED display and cameras for visual information processing. Finally, we evaluated its performance through experiments and user studies to check its acceptance level and usability of the proposed system. We compared the proposed system with a traditional video based education and an AR based system using a head mounded display (HMD). The results that the proposed system showed better performances over these systems.

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CNN-Based Hand Gesture Recognition for Wearable Applications (웨어러블 응용을 위한 CNN 기반 손 제스처 인식)

  • Moon, Hyeon-Chul;Yang, Anna;Kim, Jae-Gon
    • Journal of Broadcast Engineering
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    • v.23 no.2
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    • pp.246-252
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    • 2018
  • Hand gestures are attracting attention as a NUI (Natural User Interface) of wearable devices such as smart glasses. Recently, to support efficient media consumption in IoT (Internet of Things) and wearable environments, the standardization of IoMT (Internet of Media Things) is in the progress in MPEG. In IoMT, it is assumed that hand gesture detection and recognition are performed on a separate device, and thus provides an interoperable interface between these modules. Meanwhile, deep learning based hand gesture recognition techniques have been recently actively studied to improve the recognition performance. In this paper, we propose a method of hand gesture recognition based on CNN (Convolutional Neural Network) for various applications such as media consumption in wearable devices which is one of the use cases of IoMT. The proposed method detects hand contour from stereo images acquisitioned by smart glasses using depth information and color information, constructs data sets to learn CNN, and then recognizes gestures from input hand contour images. Experimental results show that the proposed method achieves the average 95% hand gesture recognition rate.

The relationship between organizational climate and resource linkage skills of social workers in community welfare centers: The mediating effect of reflective thinking (지역사회복지관 조직풍토와 사회복지사의 자원연계기술과의 관계: 성찰적 사고의 매개효과)

  • Park, Mijin;Hyun, Anna
    • Korean Journal of Social Welfare Studies
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    • v.48 no.2
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    • pp.203-231
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    • 2017
  • The purpose of this study is to examine the impact of organizational climate on the resource linking skills of social workers working in community welfare centers as well as the mediating effects of reflective thinking in these relationships. To test the mediating effects, we set up a research model based on previous studies on the organizational climate, resource linkage skills, and reflective thinking of social workers. The subjects of this study were social workers in community welfare centers in the Busan metropolitan city. Data were collected using mail surveys, and data from 526 respondents were used for the final analysis. The main results are as follows. First, the organizational climate of community welfare centers has a statistically significant impact on social workers' resource linkage skills. In other words, the more the social workers recognize positively about the organizational climate, the more the utilization of resource linkage skills increases. Second, reflective thinking has a mediating effect in the relationship between the organizational climate and resource linkage skills of social workers in community welfare centers. Based on the study results, practical suggestions for improved resource linkage skills and reflective thinking of social workers in community welfare centers were suggested, and practical implications and future research were discussed.

Factors Affecting the Life Satisfaction of Foreign Workers in Korea : Focusing on Educational Mismatch, Discrimination and Empowerment (외국인근로자의 삶의 만족도에 대한 영향요인 연구 : 학력 미스매치, 차별경험, 임파워먼트를 중심으로)

  • Kim, Anna;Choi, Seung-ah
    • Korean Journal of Social Welfare Studies
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    • v.48 no.2
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    • pp.331-357
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    • 2017
  • In this study, we explored the degree to which foreign workers in Korea are satisfied with their lives. We examined the extent of the respondents'educational mismatch, their experiences of discrimination, and the empowerment influence on their degree of life satisfaction. Based on this, we developed practical implications to improve foreign workers'life satisfaction in the country. The results show that life satisfaction significantly rises as the respondents'educational credentials increasingly match with the criteria for their respective jobs, given that they have not experienced discrimination and their empowerment level is high. Based on these outcomes, we proposed the following important policy measures: mediation and diminishing educational mismatch during job searches, establishing legal and institutional frameworks to prevent discrimination, and placing greater emphasis on efforts to improve foreign workers'empowerment. We expect our findings to provide an important empirical basis for efforts to facilitate foreign workers'integration into Korean society. This study is the first attempt to apply concepts such as foreign workers'empowerment and educational mismatch -as defined by the Organisation for Economic Cooperation and Development's Programme for the International Assessment of Adult Competencies (OECD PIAAC) -to foreign workers in Korea.

Youth Poverty and Employment (청년 빈곤 및 고용실태 분석)

  • Kim, Anna;Hong, Hyunwoo
    • Korean Journal of Social Welfare Studies
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    • v.49 no.2
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    • pp.93-124
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    • 2018
  • Using the Korean Survey of Household Finances and Living Conditions panel data from 2012~2016, this study analyzed youth (19~34 years) poverty and employment and examined the factors that affect employment status. The analysis revealed an increase in the proportion of young people who are students or jobless; the economic conditions of the young people varied by factors such as marital status, education, job status, and loans; and the government public transfer policy had little impact on reducing the relative poverty rate of the youth. We also examined the factors affecting the youth's employment status and the risk of being employed in low-paid jobs, using multi-logit and logit regression model respectively. Considering employment status, the older and more educated the youth were, the less frequently they were employed in temporary or daily jobs instead of regular ones, but there was no difference between genders in terms of having temporary or daily jobs. A logit analysis on the determinants of low-paid jobs demonstrated that women, the less educated, spouses or children of the household, and temporary or daily workers have a greater probability of working at low-paid jobs. As women became older, their risk of having low-paid jobs increased, which demonstrated the phenomenon of "lock-in" at low-paid jobs. Temporary or daily workers of all age groups faced a higher risk of lowpaid employment, which stood out for the youth. Based on these results, we suggest that government employment and welfare policies should consider individual characteristics of the youth and their life cycle, along with efforts to supply decent jobs, continuously and stably.