• Title/Summary/Keyword: Aniline

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KIPES2002 기념세미나-플렉소인쇄의 현황과 전망

  • Yu, Chang-Jun
    • 프린팅코리아
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    • s.4
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    • pp.60-64
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    • 2002
  • 플렉소 인쇄란 오프셋, 그라비어, 레터프레스, 스크린과 같은 하나의 인쇄 방법이다. 플렉소 인쇄는 1890년도 영국에서 "아니린(Aniline)인쇄" 라는 이름으로 등장, 발전을 거듭해 1951년 미국에서 공식 명칭을 공모, 1952년에 이르러 현재 사용하고 "Flexography" 라는 명칭을 얻게 되었다.

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Protective Effect of Diallyl Disulfide on the Bromobenzene-Induced Hepatotoxicity in Mice (Bromobenzene 간손상에 대한 Diallyl Disulfide의 예방효과)

  • Lee, Sang-Il;Yoon, Chong-Guk;Huh, Keun
    • The Korean Journal of Pharmacology
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    • v.26 no.2
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    • pp.185-192
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    • 1990
  • The present work was undertaken to investigate the protective effect of diallyl disulfide on the bromobenzene toxicity in mice. It was observed that the aniline hydroxylase and epoxide hydrolase activities were not changed by the treatment of diallyl disulfide for 5 days. But glutathione S-transferase activity was significantly increased. A striking enhancement of serum alanine aminotransferase activity and hepatic lipid peroxide content after bromobenzene administration was markedly decreased by diallyl disulfide pretreatment. These results indicate that the inducing effects of diallyl disulfide on the bromobenzene intermediate detoxifying enzyme such as glutathione S-transferase are believed to be a possible protective mechanism for the bromobenzene toxicity in mice.

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Interaction of ${\alpha}$-Ketoglutarate Dehydrogenase Complex with Allosteric Regulators Detected by a Fluorescence Probe, 1,1'-bi(4-aniline)naphthalene-5,5'-disulfonic acid, an Inhibitor of Catalytic Activity

  • Hong, Sung-Youl;Bak, Choong-Il;Ryu, Jae-Ha;Song, Byoung-J.;Huh, Jae-Wook
    • BMB Reports
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    • v.29 no.3
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    • pp.230-235
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    • 1996
  • The interaction of ${\alpha}-ketoglutarate$ dehydrogenase complex (${\alpha}-KGDC$) with a hydrophobic fluorescent probe [1,1'-bi(4-aniline)naphthalene-5,5'-disulfonic acid] (bis-ANS) was studied. The punfied ${\alpha}-KGDC$ was potently inhibited by bis-ANS with an apparent half maximal inhibitory concentration ($IC_{50}$) of 9.8 ${\mu}m$ at pH 8.0. The catalytic activities of both the E1o and E2o subunits were predominantly inhibited while that of the E3 component was hardly affected. The binding of bis-ANS to the enzyme caused a marked enhancement and blue shift from 523 nm to 482 nm in the fluorescence emission spectrum. The dissociation constant ($K_d$) and the number of binding sites (n) were calculated to be 0.87 mM and 158, respectively. Allosteric regulators such as purine nucleotides and divalent cations further increased the fluorescence intensity of the $bis-ANS-{\alpha}-KGDC$ binary complex. These data suggest that the binding of these allosteric regulators to ${\alpha}-KGDC$ may cause the conformational changes in the enzyme and that bis-ANS could be used as a valuable probe to study the interaction of the multi-enzyme complex and its allosteric regulators.

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Decomposition Characteristics of Aniline Treated in Fe2O3 Supported γ-Alumina Catalyst and O3 (Fe2O3γ-Al2O3 세라믹촉매와 오존을 이용한 아닐린의 분해특성)

  • Park, Byung-Ki;Suh, Jeong-Kwon;Lee, Jung-Min
    • Journal of the Korean Ceramic Society
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    • v.42 no.4
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    • pp.237-244
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    • 2005
  • We prepared the cylindrical $\gamma-alumina$ pellets of 5 mm in diameter and 10 mm in average length using amorphous alumina and pore generating agent. The pellets were immersed in an aqueous solution of the mixture of $Fe(NO_{3})_{3}{\cdot}9H_{2}O$ and $CH_{3}COOH$. They were then hydrothermally treated at $200^{\circ}C$ for 3 h in autoclave, dried and calcined. For the application as an environmental catalyst, we investigated the decomposition characteristics of aniline and the initiation characteristics of $OH^{\cdot}$ conversion action in $O_{3}$ environment with or without the $Fe_{2}O_{3}$ supported y-alumina catalyst and $O_{3}$ molecule.

The utility of sperm DNA damage assay using toluidine blue and aniline blue staining in routine semen analysis

  • Kim, Hee-Sun;Kang, Moon Joo;Kim, Sung Ah;Oh, Sun Kyung;Kim, Hoon;Ku, Seung-Yup;Kim, Seok Hyun;Moon, Shin Yong;Choi, Young Min
    • Clinical and Experimental Reproductive Medicine
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    • v.40 no.1
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    • pp.23-28
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    • 2013
  • Objective: The aim of the present study was to examine the relationship among male age, strict morphology, and sperm chromatin structure and condensation. Methods: Sperm samples from a total of 100 men underwent semen analysis, and sperm chromatin structure and condensation were assessed with toluidine blue (TB) and aniline blue (AB) tests. Results: Prevalence of strict morphology of less than 4%, and abnormal sperm chromatin structure and condensation did not show any statistically significant differences according to male age (p=0.605, p=0.235, and p=0.080). No significant correlation was demonstrated among age of male partners, strict morphology, and abnormal sperm chromatin structure using TB and AB tests. However, abnormal sperm chromatin condensation was positively associated with sperm chromatin structure (r=0.594, p=0.000) and showed negative correlation with strict morphology (r=-0.219, p=0.029). Conclusion: The tests for sperm chromatin condensation showed a significant association with strict morphology. Further study is needed to elucidate the relationship between clinical outcome and sperm chromatin tests.

The Effects of Houttuynia cordata on the Hepatic Bromobenzene Metabolizing Enzyme System in Rats and Isolation of Phenolic Compounds (흰쥐의 브로모벤젠대사계에 미치는 어성초의 영향과 페놀성 화합물의 분리)

  • Hur, Jong-Moon;Park, Ju-Gwon;Park, Sung-Jong;Lee, Jong-Ho;Sung, Nak-Ju;Choi, Myeong-Rak;Song, Sang-Ho;Kim, Moon-Sung;Choi, Jong-Won;Park, Jong-Cheol
    • Korean Journal of Pharmacognosy
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    • v.31 no.2
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    • pp.228-234
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    • 2000
  • Effects of Houttuynia cordata on the level of lipid peroxide and the enzyme activities of the liver were investigated in bromobenzene-induced rats. Lipid peroxide content in liver was increased by bromobenzene. It was decreased when the methanol extract from the aerial parts of H. cordata was treated to the rat. The methanol extract reduced the activities of aminopyrine N-demethylase and aniline hydroxylase that increased by bromobenzene, however did not affect glutathione S-transferase activity. The methanol extract recovered the activity of epoxide hydrolase activity that decreased significantly by bromobenzene. We suggest that under our experimental conditions the extract might play an important play in the prevention of hepatotoxicity by reduction of aminopyrine N-demethylase and aniline hydroxylase activities as well as enhancement of epoxide hydrolase activity. Six phenolic compounds have been isolated from H. cordata and identified by means of spectral analysis as protocatechuic acid, quercetin, apigenin, afzelin, hyperoside and quercitrin.

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