• Analytical Science and Technology
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• v.5 no.2
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• pp.1067-1082
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• 1992

• YAKHAK HOEJI
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• v.58 no.3
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• pp.190-199
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• 2014

The Korean Pharmaceutical Codex (KPC) analytical method of ambroxol hydrochloride and clenbuterol hydrochloride formulation is complicated and needed to carry out multiple processes during the test. To improve the low efficiency of analytical procedure that makes pharmaceutical laboratory consume much time and high cost to conduct the test of this formulation, this study was performed for simplifying the pretreatment process and optimizing conditions of the HPLC assay. The analytical procedure using HPLC was developed to establish analytical specification for ambroxol hydrochloride and clenbuterol hydrochloride formulations. The newly developed analytical method has good linearity ($R^2$ >0.999), specificity, precision (RSD<1.0%) and the recovery ranges of 98.50~101.84% for ambroxol, 98.29~101.35% for clenbuterol syrup and 98.66~101.71% for clenbuterol tablets. The LOQs were 0.204 ${\mu}g/ml$ for ambroxol, 0.021 ${\mu}g/ml$ for clenbuterol syrup and 0.073 ${\mu}g/ml$ for clenbuterol tablets. The new method was performed with commercially available samples to confirm analytical conditions and validated to be suitable for saving time and cost to control the quality of routine manufactured products. This analytical method will be used for revising the monograph of ambroxol hydrochloride and clenbuterol hydrochloride formulation in next supplement of KPC.

• Journal of the Korean Society of Hazard Mitigation
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• v.11 no.3
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• pp.111-116
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• 2011

Analytical solutions for laterally loaded piles were derived. Critical pile length which can be considered as the length for behaving as long pile was investigated varying with densities of sandy soils. Lateral behaviors obtained from analytical solution and numerical solution were also investigated. Non-dimensional critical pile lengths obtained from analytical solutions for three types of pile head boundary conditions were 2.3~3.2. By comparing analytical solutions with numerical solutions, distribution of pile deflection and that of moment were similar and it can be seen that pile head deflection obtained by analytical method is conservative. And the values of moments were not too different between analytical solution and numerical solution.

• International journal of steel structures
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• v.18 no.4
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• pp.1440-1463
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• 2018

The Wagner coefficient is a key parameter used to describe the inelastic lateral-torsional buckling (LTB) behaviour of the I-beam, since even for a doubly-symmetric I-section with residual stress, it becomes a monosymmetric I-section due to the characteristics of the non-symmetrical distribution of plastic regions. However, so far no theoretical derivation on the energy equation and Wagner's coefficient have been presented due to the limitation of Vlasov's buckling theory. In order to simplify the nonlinear analysis and calculation, this paper presents a simplified mechanical model and an analytical solution for doubly-symmetric I-beams under pure bending, in which residual stresses and yielding are taken into account. According to the plate-beam theory proposed by the lead author, the energy equation for the inelastic LTB of an I-beam is derived in detail, using only the Euler-Bernoulli beam model and the Kirchhoff-plate model. In this derivation, the concept of the instantaneous shear centre is used and its position can be determined naturally by the condition that the coefficient of the cross-term in the strain energy should be zero; formulae for both the critical moment and the corresponding critical beam length are proposed based upon the analytical buckling equation. An analytical formula of the Wagner coefficient is obtained and the validity of Wagner hypothesis is reconfirmed. Finally, the accuracy of the analytical solution is verified by a FEM solution based upon a bi-modulus model of I-beams. It is found that the critical moments given by the analytical solution almost is identical to those given by Trahair's formulae, and hence the analytical solution can be used as a benchmark to verify the results obtained by other numerical algorithms for inelastic LTB behaviour.

• International Journal of Computer Science & Network Security
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• v.21 no.3
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• pp.134-140
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• 2021

The development of technology speeds up the process of obtaining information and its analysis to track the level of corruption in different countries and develop countermeasures. This study examines the role of information and analytical support of anti-corruption policy as a tool for government accountability and analysis, evaluation, combating corruption in Eastern Europe. The purpose of the article is to identify the components of the information-analytical system that help reduce the level of corruption. The research methodology is based on a qualitative content analysis of the functioning of information and analytical systems of Ukraine used by anti-corruption bodies. A quantitative analysis of the CPI score was conducted, according to Transparency International, to identify the effectiveness of anti-corruption policies in developing countries. The results show similar trends in countries developing on the effect of the use of information and analytical systems in the implementation of anti-corruption policies, strategies and measures. The strategy to combat corruption mainly involves increasing the independence and powers of anti-corruption bodies. Therefore, the development of information and analytical support is aimed at automating the processes of pre-trial investigations and criminal proceedings, information protection. As a tool for accountability, information and analytical systems may be ineffective due to the abuse of power by higher anti-corruption bodies due to political pressure from elite structures. Restrictions on political will are a major problem for the effectiveness of anti-corruption policies.

• Wind and Structures
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• v.36 no.3
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• pp.161-174
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• 2023

The analytical model of tornado vortices plays an essential role in tornado wind description and tornado-resistant design of civil structures. However, there is still a lack of guidance for the selection and application of tornado analytical models since they are different from each other. For single-cell tornado vortices, this study conducts a comparative study on the velocity characteristics of the analytical models based on numerically simulated tornado-like vortices (TLV). The single-cell stage TLV is first generated by Large-eddy simulations (LES). The spatial distribution of the three-dimensional mean velocity of the typical analytical tornado models is then investigated by comparison to the TLV with different swirl ratios. Finally, key parameters are given as functions of swirl ratio for the direct application of analytical tornado models to generate full-scale tornado wind field. Results show that the height of the maximum radial mean velocity is more appropriate to be defined as the boundary layer thickness of the TLV than the height of the maximum tangential mean velocity. The TLV velocity within the boundary layer can be well estimated by the analytical model. Simple fitted results show that the full-scale maximum radial and tangential mean velocity increase linearly with the swirl ratio, while the radius and height corresponding to the position of these two velocities decrease non-linearly with the swirl ratio.

• Polymer Science and Technology
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• v.24 no.4
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• pp.352-360
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• 2013

• Analytical Science and Technology
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• v.28 no.3
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• pp.139-159
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• 2015

• Analytical Science and Technology
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• v.16 no.4
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• pp.1029-1040
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• 2003

• Analytical Science and Technology
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• v.14 no.5
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• pp.1083-1108
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• 2001